WO2005007068A1 - Systeme d'emballage de nicotine - Google Patents
Systeme d'emballage de nicotine Download PDFInfo
- Publication number
- WO2005007068A1 WO2005007068A1 PCT/NZ2004/000156 NZ2004000156W WO2005007068A1 WO 2005007068 A1 WO2005007068 A1 WO 2005007068A1 NZ 2004000156 W NZ2004000156 W NZ 2004000156W WO 2005007068 A1 WO2005007068 A1 WO 2005007068A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gel
- nicotine
- packaging system
- mouth
- packaging
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Definitions
- the invention relates to a nicotine or tobacco product and in particular to a novel packaging system for nicotine or tobacco products in the form of a liquid or gel.
- Tobacco products are predominately smoked. Exceptions to this are tobacco snuff, chewing tobacco, tobacco lozenges and buccal tobacco products.
- Smoking tobacco has well documented deleterious risks on the user from the toxic effects of nicotine and the combustion of tars and related chemicals in tobacco. There are similar local and systemic risks associated with tobacco snuff, chewing tobacco, tobacco lozenges and buccal tobacco products.
- the primary agent that drives people to smoking or using tobacco products is the vsry addictive chemical nicotine.
- nicotine shares the toxic effects with other chemicals in tobacco such as the tars. When smoked these effects are also imposed upon bystanders, not necessarily by choice.
- the invention needs to deliver nicotine rapidly to the user to come close to the rapidity of nicotine delivery from smoking a cigarette.
- the invention's delivery system will mimic the ritual of smoking behaviour, that is, repetitive hand to moilh administration.
- the invention needs to be manufactured at a cost that will not be prohibitive for the consumer.
- the invention provides a gel containing a tobacco concentrate.
- the tobacco concentrate contains a standardised level of nicotine.
- the tobacco concentrate preferably contains little or no fibre and more preferably contains minimal tars.
- the nicotine content per unit of the gel is preferably between 0.1 and 20 mg.
- the gel has a disintegration time of less than 2 minutes at body temperature.
- the gel is preferably soluble in saliva.
- the gel may be packaged in a system that allows the user to mimic the hand to mouth repetitive administration of a standard cigarette when delivering the gel to their mouth.
- the gel is preferably packaged in a system including a plastic envelope on a backing card and the system is adapted to be manually disrupted to expel the gel.
- the gel may contain natural or artificial flavouring and/or sweeteners to make it palatable.
- the opening of the packaging system and delivery of the gel to a user's mouth mimics the hand to mouth action of smoking a cigarette.
- a point of weakness is found at one position in the system such that in use, the system can be opened by a user to release the gel by breaking the package at the point of weakness.
- the package may be opened by a user applying pressure to the point of weakness.
- the point of weakness may be at the mid point along the packaging system's length or may be situated to one side of the packaging system.
- the invention provides a nicotine deliver ⁇ ' system including: a packaging system containing a gel.
- the gel containing a concentrate including a standardized level of nicotine; and wherein the packaging system is adapted to be opened by a user such that the gel is able to be released into the user ' s mouth.
- the invention provides a packaging system for a nicotine gel comprising: a) a plastic sealing system adhered to a backing sheet; b) a nicotine gel concentrate inside the plastic sealing system; c) a position of weakness in the packaging system such that the application of pressure to the position of weakness results in the opening of the plastic sealing system and possible removal of the nicotine containing gel.
- Figure 1 is a packaging system for the gel;
- Figure 2 shows the gel packaging system after use;
- Figure 3 shows a further embodiment of a gel packaging system
- Figure 4 shows a further embodiment of a gel packaging system
- Figure 5 shows a further embodiment of a gel packaging system
- Figure 6 shows a further embodiment of a gel packaging system.
- the product is a nicotine delivery system including a nicotine-containing gel packaged in a delivery system that is adapted to be opened by a user such that the nicotine- containing gel is delivered to the user ' s mouth mimicking the hand to mouth movement of a smoker when smoking a cigarette.
- Figure 1 shows a card shaped pack 2.
- the pack 2 has a semi-rigid backing material 4.
- the backing material 4 may be made from one or more sections and may be made of any suitable material.
- a first layer of thin plastic film 6 is sealed onto one side of the backing material 4.
- a second piece of plastic film 8 extends above the first, the two pieces of film 6 and 8 being sealed together at the ends of the backing material A and B.
- a breaking point 14 in the backing material 4 is provided.
- the breaking point 14 may be formed due to a weakness in the backing material 4. Examples of this would be the incorporation of a weaker material at this point, a physical groove or score in a semi-rigid material.
- the breaking point 14 of the semi-rigid material may occur at any point or extremity on/within the semi-rigid material.
- the film can be either formed from one piece or multiple pieces joined together.
- the film is flexible and can be made from plastic, metal foil, composite foils, paper film or any other suitable material.
- the semi-rigid material may either partially or completely enclose the film.
- the semi-rigid material may be composed of plastic, plastic composite, cardboard, composite or bonded mats, metals, metal composites or any material that may impart semi-rigid characteristics.
- the semi-rigid material may be any shape, examples of which are to be found in Figures
- Figure 1 shows one preferred example of the packaging system for nicotine or tobacco gel or liquids.
- the packaging system 2 is opened at the break point 14 by bending the semi-rigid material 4 either side of the break point 14 together.
- the film breaks and expels the gel 12 from inside the packaging system 2. This is shown in Figure 2.
- the user then brings the opened packaging system up to their mouth and tips the gel into their mouth.
- the bringing up of the packaging system towards the user's mouth mimics the hand to mouth action of a cigarette smoker when smoking a cigarette.
- Any tobacco or nicotine gel or liquid may be used inside the packaging system.
- a preferred example of a tobacco gel containing standardised nicotine is prepared as follows:
- Tobacco concentrate is prepared by first extracting solensol and organic acids using a dry super critical fractionated extraction (SCFE) process (high pressure, low temperature CO2) from the raw tobacco. The solensol and organic acid component is then discarded;
- SCFE dry super critical fractionated extraction
- the raw tobacco then undergoes a wet SCFE to remove the nicotine containing components.
- the rest of the tobacco is then discarded.
- the wet SCFE product is the tobacco concentrate that is used for the active ingredient in the gel;
- Nicotine/Tobacco concentrate Base 1000 *as per required dosage
- Peppermint Flavour 2 Water to volume to 1 litre Ginger
- Ginger Flavour 2 Water to volume to 1 litre
- the advantages of the present invention include: 1. A non-combustible tobacco product.
- the product is for oral use.
- the product contains a standardised amount of nicotine.
- the product contains minimal tar.
- the product contains minimal organic fibre.
- the product is palatable.
- the products delivery system can mimic the hand to mouth ritual of smoking a cigarette.
- the invention provides a product that can be used by smokers to assist them to quit smoking or to replacing smoking a traditional type cigarette.
- the nicotine system will reduce the health risk to smokers who use it.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ52711503 | 2003-07-22 | ||
NZ527115 | 2003-07-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005007068A1 true WO2005007068A1 (fr) | 2005-01-27 |
Family
ID=34075194
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/NZ2004/000156 WO2005007068A1 (fr) | 2003-07-22 | 2004-07-22 | Systeme d'emballage de nicotine |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2005007068A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021127097A3 (fr) * | 2019-12-19 | 2021-09-10 | Juul Labs, Inc. | Compositions de gel de nicotine à base organique |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988003803A1 (fr) * | 1986-11-18 | 1988-06-02 | Forschungsgesellschaft Rauchen Und Gesundheit Mbh | Capsule a administration orale avec un milieu fluide contenant de la nicotine |
GB2299756A (en) * | 1995-03-29 | 1996-10-16 | Gilbert Falkingham Clayton | Gelatinous pastille containing nicotine |
US5799663A (en) * | 1994-03-10 | 1998-09-01 | Elan Medical Technologies Limited | Nicotine oral delivery device |
US20020125164A1 (en) * | 2000-12-21 | 2002-09-12 | Bassinson Oscar M. | Personal medical dispensing card |
-
2004
- 2004-07-22 WO PCT/NZ2004/000156 patent/WO2005007068A1/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988003803A1 (fr) * | 1986-11-18 | 1988-06-02 | Forschungsgesellschaft Rauchen Und Gesundheit Mbh | Capsule a administration orale avec un milieu fluide contenant de la nicotine |
US5799663A (en) * | 1994-03-10 | 1998-09-01 | Elan Medical Technologies Limited | Nicotine oral delivery device |
GB2299756A (en) * | 1995-03-29 | 1996-10-16 | Gilbert Falkingham Clayton | Gelatinous pastille containing nicotine |
US20020125164A1 (en) * | 2000-12-21 | 2002-09-12 | Bassinson Oscar M. | Personal medical dispensing card |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021127097A3 (fr) * | 2019-12-19 | 2021-09-10 | Juul Labs, Inc. | Compositions de gel de nicotine à base organique |
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