WO2004107985A1 - Procede et dispositif de prelevement, de transport et de conservation d'echantillons de selles - Google Patents

Procede et dispositif de prelevement, de transport et de conservation d'echantillons de selles Download PDF

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Publication number
WO2004107985A1
WO2004107985A1 PCT/DE2004/001106 DE2004001106W WO2004107985A1 WO 2004107985 A1 WO2004107985 A1 WO 2004107985A1 DE 2004001106 W DE2004001106 W DE 2004001106W WO 2004107985 A1 WO2004107985 A1 WO 2004107985A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
sample
stool sample
sampler
volume
Prior art date
Application number
PCT/DE2004/001106
Other languages
German (de)
English (en)
Inventor
Walter Sarstedt
Original Assignee
Sarstedt Ag & Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarstedt Ag & Co. filed Critical Sarstedt Ag & Co.
Priority to EP04738575A priority Critical patent/EP1628578A1/fr
Publication of WO2004107985A1 publication Critical patent/WO2004107985A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0038—Devices for taking faeces samples; Faecal examination devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber

Definitions

  • the invention relates to a method and a device for transferring a removed stool sample for its transport and / or storage in a container which has a piston means at its closure-side end.
  • the spoon If the spoon is ejected into the container while the entire device is held vertically, the stool sample on or in the spoon comes into contact with the liquid medium. However, it cannot be avoided that part of the sample adheres to the spoon and is then not completely washed around by the medium. In addition, the spoon remains as a waste product in the sample and medium mixture to be analyzed, with which a stool sample of the same volume cannot be achieved.
  • a device for achieving sample sections of equal volume is known from DE 197 31 831 C2, but requires several components. The person taking the sample is therefore required to work with the multi-part device with a high level of successive steps.
  • Another disadvantage is the guidance of the sample volume sampler. This has only one leading edge and can dodge if used improperly. Even with great care by the person taking a sample, it cannot be ruled out that a required sample ejector will not hit the opposite opening when it is inserted laterally into a sampling opening and consequently cannot exit there. The sample ejector hits the opening edges on the right or left. However, this prevents a sample of the same volume.
  • a stool sample is sucked into a sample vessel with the aid of a negative pressure generated by a piston rod arrangement.
  • the entire sample container is then placed in a transport and / or storage housing, which is then closed.
  • the stool sample remaining in the sample container will age and e.g. reacts with the air and dries up.
  • the invention is therefore based on the object of creating a method and an apparatus of the type mentioned at the outset without the disadvantages described, which in particular enable samples of the same volume with little effort or fewer work steps.
  • a small-volume sampler of a certain absorption capacity that can be temporarily removed from the container is completely filled with the stool sample, then from the The closure side is inserted deep into the container and the entire stool sample taken, with the sampler remaining in the container, is pressed out of the sampler with the piston means and emptied into the container.
  • a stool sample can thus be simply wiped off with the help of a spatula or the like until it is flush with the edge of the circumferentially closed receiving space of the sampler, optionally provided with a ventilation slot, until the receiving space is completely filled. This means that the same amount can always be achieved for each sample.
  • the axially displaceable piston means withdrawn for filling acts as a defined volume limiter.
  • the much smaller sample volume compared to the container volume can then be emptied into the container in a targeted and complete manner by pressing in the piston means. If this is preferably filled with a medium that is liquid to preserve the stool sample, the defined small-volume stool sample is washed around the entire circumference of the medium immediately after it has been ejected and remains throughout the entire transport and / or storage period.
  • the piston means is arranged in a sample-receiving space which is designed like a stopper on a closure lid of the container and immerses to a limited depth in the container.
  • the closure means preferably embodied as a cap that can be screwed onto the container, not only reduces the components required for the sample-taking device with the associated simple handling due to its one-piece design with the sample-receiving space.
  • it also simultaneously provides the space for receiving an amount of stool sample which is always of the same volume and also serves as a carrier for the axially displaceable piston means which ejects the sample.
  • FIG. 1 shows a longitudinal section of an overall device for transporting and / or storing a stool sample with a closure cap, which always enables the same volume to be taken into a receiving space, with a piston arranged in the receiving space, in its retracted position;
  • Fig. 2 is an illustration as shown in FIG. 1 with the piston pressed in.
  • a means 1 for taking or receiving the stool sample 2 in the exemplary embodiment consists of a screw cap 3 with an integrally formed one, which provides for constant volume withdrawals Sampler 5 having receiving space 4.
  • a piston 6 is arranged axially displaceably in the tubular receiving space 4 and is connected to a plunger 8 for actuation from the outside via a piston rod 7.
  • the retracted end position of the piston 6 according to FIG. 1 is defined in a defined manner by a stop 9 formed in the screw cap 3.
  • the piston rod 7 is provided with a holding means 10 that projects over a neck 11 that extends the stop 9, but overcomes it easily under the action of the pressing force.
  • the upper edge of the collar 11 simultaneously forms a stop for the tappet 8, so that the ejection stroke is also limited to the necessary extent.
  • an always equal volume of sample can be given, e.g. be filled up with the help of a spatula so that the stool sample completely fills the volume of the receiving space 4 delimited by the withdrawn piston 6 and is flush with the lower, free edge of the tubular sampler 5.
  • a quantity of a stool sample 2, which has been defined in this way by means 1, is transported and / or stored according to the exemplary embodiment into a storage medium 12, which is filled with a storage medium 12 and is opposite the receiving space 4 in Volume of much larger container 13 transferred.
  • the screw cap 3 is screwed onto the container 13 (cf. FIG. 1), and when the piston 6 is then pressed down into its ejection position according to FIG. 2 by means of the plunger 8, the stool sample 2 falls down. From the first contact with the shelf life medium 12 and then continuously during the entire transport or the storage period, it is completely washed around the medium 12.
  • the screw cap 3 secures the closure of the container 13 during the entire residence time.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne un procédé de transfert d'échantillons de selles prélevés (2), consistant à transporter et/ou à conserver lesdits échantillons dans un contenant (13) présentant un élément piston (6, 7, 8) sur son extrémité côté fermeture. Selon ledit procédé, un élément de prélèvement d'échantillons (5) de faible volume, présentant une capacité de réception définie, pouvant être temporairement retiré du contenant, est entièrement rempli d'échantillons de selles, logé profondément dans le contenant (13) de façon délimité par le côté de fermeture, et l'ensemble des échantillons de selles prélevés (2) est expulsé hors de l'élément de prélèvement d'échantillons (5) au moyen de l'élément piston (6, 7, 8), ce dernier restant dans le contenant (13), et vidé dans le contenant (13). A cet effet, l'élément piston (6, 7, 8) est logé dans un espace de réception d'échantillons (4) profondément immergé dans le contenant de façon délimitée par un élément de fermeture (3) du contenant (13), conçu à la manière d'un bouchon.
PCT/DE2004/001106 2003-05-30 2004-05-26 Procede et dispositif de prelevement, de transport et de conservation d'echantillons de selles WO2004107985A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04738575A EP1628578A1 (fr) 2003-05-30 2004-05-26 Procede et dispositif de prelevement, de transport et de conservation d'echantillons de selles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2003124913 DE10324913A1 (de) 2003-05-30 2003-05-30 Verfahren und Vorrichtung zur Stuhlprobenentnahme
DE10324913.3 2003-05-30

Publications (1)

Publication Number Publication Date
WO2004107985A1 true WO2004107985A1 (fr) 2004-12-16

Family

ID=33482380

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2004/001106 WO2004107985A1 (fr) 2003-05-30 2004-05-26 Procede et dispositif de prelevement, de transport et de conservation d'echantillons de selles

Country Status (3)

Country Link
EP (1) EP1628578A1 (fr)
DE (1) DE10324913A1 (fr)
WO (1) WO2004107985A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015139645A1 (fr) * 2014-03-20 2015-09-24 单希杰 Dispositif de retenue de fluide corporel scellé jetable
CN107044918A (zh) * 2017-03-07 2017-08-15 无锡圣诺亚科技有限公司 大便取检器
EP2720616B1 (fr) 2011-06-14 2021-02-24 Frost Diagnostika GmbH Dispositif pour le prélèvement et le traitement d'un échantillon
US11002646B2 (en) 2011-06-19 2021-05-11 DNA Genotek, Inc. Devices, solutions and methods for sample collection
US11572581B2 (en) 2002-06-07 2023-02-07 DNA Genotek, Inc. Compositions and methods for obtaining nucleic acids from sputum

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012023492A1 (de) * 2012-12-03 2014-06-05 Prionics Ag Behälter
CN108871908B9 (zh) * 2018-09-06 2024-07-26 杭州优思达生物技术股份有限公司 生物样本处理装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835358B1 (de) * 1978-08-11 1979-12-06 Greiner & Soehne C A Gefaess fuer biochemische und immunologische Untersuchungen
EP0727653A2 (fr) * 1995-02-15 1996-08-21 Wako Pure Chemical Industries, Ltd Dispositif de prélèvement des fèces

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835358B1 (de) * 1978-08-11 1979-12-06 Greiner & Soehne C A Gefaess fuer biochemische und immunologische Untersuchungen
EP0727653A2 (fr) * 1995-02-15 1996-08-21 Wako Pure Chemical Industries, Ltd Dispositif de prélèvement des fèces

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11572581B2 (en) 2002-06-07 2023-02-07 DNA Genotek, Inc. Compositions and methods for obtaining nucleic acids from sputum
EP2720616B1 (fr) 2011-06-14 2021-02-24 Frost Diagnostika GmbH Dispositif pour le prélèvement et le traitement d'un échantillon
US11002646B2 (en) 2011-06-19 2021-05-11 DNA Genotek, Inc. Devices, solutions and methods for sample collection
US11536632B2 (en) 2011-06-19 2022-12-27 DNA Genotek, Inc. Biological collection system
US11549870B2 (en) 2011-06-19 2023-01-10 DNA Genotek, Inc. Cell preserving solution
US11592368B2 (en) 2011-06-19 2023-02-28 DNA Genotek, Inc. Method for collecting and preserving a biological sample
WO2015139645A1 (fr) * 2014-03-20 2015-09-24 单希杰 Dispositif de retenue de fluide corporel scellé jetable
CN107044918A (zh) * 2017-03-07 2017-08-15 无锡圣诺亚科技有限公司 大便取检器
CN107044918B (zh) * 2017-03-07 2023-10-20 无锡圣诺亚科技有限公司 大便取检器

Also Published As

Publication number Publication date
EP1628578A1 (fr) 2006-03-01
DE10324913A1 (de) 2004-12-30

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