WO2004095047A1 - Dispositif de generation de champ magnetique uniforme et dispositif de resonance magnetique nucleaire mettant en oeuvre celui-ci - Google Patents
Dispositif de generation de champ magnetique uniforme et dispositif de resonance magnetique nucleaire mettant en oeuvre celui-ci Download PDFInfo
- Publication number
- WO2004095047A1 WO2004095047A1 PCT/JP2004/005978 JP2004005978W WO2004095047A1 WO 2004095047 A1 WO2004095047 A1 WO 2004095047A1 JP 2004005978 W JP2004005978 W JP 2004005978W WO 2004095047 A1 WO2004095047 A1 WO 2004095047A1
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- WIPO (PCT)
- Prior art keywords
- magnetic field
- superconducting
- coil group
- uniform magnetic
- shim coil
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
- G01R33/387—Compensation of inhomogeneities
- G01R33/3875—Compensation of inhomogeneities using correction coil assemblies, e.g. active shimming
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
- G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
- G01R33/381—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets
- G01R33/3815—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets with superconducting coils, e.g. power supply therefor
Definitions
- the present invention relates to a uniform magnetic field generator and a nuclear magnetic resonance (NMR) apparatus using the same.
- NMR nuclear magnetic resonance
- NMR systems generally use superconducting main coils 1 to 3 that generate a magnetic field in the measurement space and superconducting coils that correct the non-uniformity of the magnetic field generated by the superconducting main coils 1 to 3.
- the shim coil groups 4a to 4f, and the superconducting main coil groups 1 to 3 and the superconducting shim coil groups 4a to 4: f include a normal temperature shim coil group 5 for more precisely correcting the generated substantially uniform magnetic field.
- the superconducting shim coil groups 4 a to 4 f constitute an electric circuit separated from the superconducting main coil groups 1 to 3, and the value of the current flowing through the superconducting shim coil group 5 is the value of the current flowing through the superconducting main coil groups 1 to 3. It can be determined independently of the value. Note that, in the schematic cross-sectional view of FIG. 7, the display of the winding frames that support each coil is omitted.
- the superconducting main coil groups 1 to 3 are composed of a plurality of coils having a common central axis.
- a port for inserting a test tube 6 containing a sample and a probe 7 penetrates near the central axis of the superconducting main coil groups 1 to 3 as shown in FIG.
- the probe 7 is inserted from below.
- the probe 7 is provided with an NMR signal detection antenna 8.
- the detection antenna 8 responds to the magnetic field (in the direction parallel to the central axis) generated by the superconducting main coil groups 1 to 3. . ⁇
- the superconducting shim coil groups 4a to 4f are all installed outside the superconducting main coil groups 1 to 3. Therefore, the magnetic field required by the superconducting shim coil groups 4a to 4f is less than 8 Tesla, even for the NMR apparatus which achieves the highest central magnetic field of 22 Tesla at present. Therefore, an NbTi superconducting wire with a low upper critical magnetic field (a magnetic field at which the critical current density becomes zero) can be used.
- the above conventional technology has the following problems. Because the measurement space is far from the superconducting shim coil groups 4a to 4: f, there is an upper limit to the magnitude of the magnetic field that the superconducting shim coil groups 4a to 4f can generate in the measurement space. In particular, it is not possible to efficiently generate a magnetic field component that is proportional to the higher order (4th order or higher) of the axial coordinates. Therefore, the superconducting shim coil groups 4 a to 4 ⁇ ⁇ ⁇ may lack the magnetic field correction capability.
- the first case in which the superconducting shim coils 4a to 4f group lacks the ability to correct the magnetic field is that the superconducting main coil groups 1 to 3 and the superconducting shim coil groups 4a to 4f This is a case where the axial length is shortened. When the axial length of the superconducting main coil groups 1 to 3 is reduced, the irregular magnetic field generally increases, so that the requirements for the superconducting shim coil groups 4a to 4f become strict.
- the superconducting shim coil groups 4a to 4f lack the ability to correct the magnetic field.
- the second case in which the superconducting shim coil groups 4a to 4f lacks the magnetic field correction capability is to split the superconducting main coil groups 1 to 3 in the axial direction so that a highly sensitive solenoid-type detection antenna can be used Insert the test tube containing the sample into the measurement space through the gap.
- This is a case where the apparatus configuration is as follows (hereinafter referred to as a split type).
- an irregular magnetic field proportional to the higher order of the axial coordinates is generated more than before.
- the fourth-order component of the axial coordinate reaches about 25 times the conventional value
- the 6th-order component reaches about 50 times the conventional value.
- These higher-order magnetic field components cannot be generated by the superconducting shim coil groups 4a to 4f installed outside the superconducting main coil groups 1 to 3.
- the room-temperature shim coil group 5 can generate a higher-order magnetic field component, but the magnetic field correction ability is generally small due to the upper limit of the current that can be passed, and the above-described irregular magnetic field cannot be corrected.
- an object of the present invention is to provide a uniform magnetic field generator including a superconducting shim coil group having a high ability to correct a high-order magnetic field in the axial direction. Disclosure of the invention
- a uniform magnetic field generation device includes a superconducting main coil group for generating a magnetic field in a measurement space, and a superconducting shim coil group for correcting the non-uniformity of the magnetic field, and has a radial position corresponding to the superconducting main coil group. At least one coil of the superconducting shim coil group is provided between the measurement space and an axial position different from each coil constituting the superconducting main coil group.
- the correction coil (corresponding to the superconducting shim coil in the present specification) is larger than the main magnet coil (corresponding to the superconducting main coil in the present specification).
- the correction coil is installed at the same axial position as the main magnet coil, which is different from the present invention.
- At least one coil of the superconducting shim coil group is operated in a high magnetic field of 8 Tesla or more.
- At least one coil of the superconducting shim coil group is made of a superconducting wire having an upper critical magnetic field of 14 Tesla or more. It is, for example, an Nb3Sn superconducting wire. Further, in the uniform magnetic field generator of the present invention, the superconducting shim coil group includes a plurality of coils having different distances from a central axis.
- the superconducting shim coil group generates a magnetic field component that is fourth-order proportional to the axial coordinate within a range of 10 mm from the center of the measurement space by 0.1 Gauss or more.
- the superconducting shim coil group generates a magnetic field component of 0.006 gauss proportional to the sixth order of the axial coordinate within a range of 10 mm from the center of the measurement space. Has the ability to generate more.
- At least one coil of the superconducting shim coil group simultaneously generates a plurality of orders of magnetic field components.
- a plurality of orders of magnetic field components are corrected simultaneously by independently controlling the value of the current supplied to each coil of the superconducting shim coil group.
- the superconducting main coil group includes a first superconducting main coil group and a second superconducting main coil group opposed to each other via an axial gap.
- FIG. 1 is a schematic cross-sectional view of the uniform magnetic field generator according to the first embodiment.
- FIG. 2 is a schematic sectional view of a uniform magnetic field generator according to the second embodiment.
- FIG. 3 is a schematic sectional view of a uniform magnetic field generator according to the third embodiment.
- FIG. 4 is a schematic sectional view of a uniform magnetic field generator according to the fourth embodiment.
- FIG. 5 is a schematic sectional view of a uniform magnetic field generator according to a fifth embodiment.
- FIG. 6 is a perspective view of a conventional uniform magnetic field generator.
- FIG. 7 is a schematic sectional view of a conventional uniform magnetic field generator. BEST MODE FOR CARRYING OUT THE INVENTION
- FIG. 1 is a schematic sectional view of a uniform magnetic field generator according to the present embodiment.
- the NMR system uses superconducting shim coils to correct the non-uniformity of the magnetic field generated by the superconducting main coils 1-3 and superconducting main coils 1-3 to generate a magnetic field in the measurement space in order to achieve high uniformity of the magnetic field.
- the superconducting main coil groups 1 to 3 and the superconducting shim coil groups 4 a to 4 f include a normal temperature shim coil group 5 for more precisely correcting the generated substantially uniform magnetic field.
- the superconducting shim coil groups 4a to 4 ⁇ constitute an electric circuit separated from the superconducting main coil groups 1 to 3, and the current flowing through the superconducting shim coil group 5 flows through the superconducting main coil groups 1 to 3. It can be determined independently of the current value.
- the illustration of the bobbin supporting each coil is omitted.
- the superconducting main coil groups 1 to 3 are composed of a plurality of coils having a common central axis.
- the superconducting main coil groups 1 to 3 extend in the direction of the central axis, and the distances between the coils 1 to 3 and the central axis are different.
- Ports for inserting the test tube 6 containing the sample and the probe 7 penetrate the vicinity of the central axis of the superconducting main coil groups 1 to 3, the test tube 6 from above and the probe 7 from below. , Respectively inserted.
- the probe 7 is provided with an NMR signal detection antenna 8.
- the detection antenna 8 needs to have sensitivity to a magnetic field in a direction perpendicular to a magnetic field (a direction parallel to the central axis) generated by the superconducting main coil groups 1 to 3, and a conventional saddle type Or a birdcage-type detection antenna is used.
- the superconducting shim coil groups 4 a to 4 f are all installed outside the superconducting main coil groups 1 to 3 and are located at approximately the same distance from the central axis. Therefore, the magnetic field required by the superconducting shim coil groups 4a to 4f is the highest central magnetic field of 22 Tesla at present. ⁇
- an NbTi superconducting wire having a low upper critical magnetic field (a magnetic field at which the critical current density becomes zero) can be used.
- the device of this embodiment is shorter in the axial direction.
- the superconducting shim coil groups 4a to 4 consist of the superconducting main coil groups 1 to 3 and the room temperature shim coil group in addition to the first superconducting shim coil groups 4a to 4f installed outside the superconducting main coil groups 1 to 3.
- the second superconducting shim coil groups 9a to 9d are installed.
- the second superconducting shim coil groups 9a to 9d are located at approximately the same distance from the central axis.
- the second superconducting shim coil groups 9a to 9d are required to function in a magnetic field of 8 Tesla or more. Therefore, the coils constituting the second superconducting shim coil groups 9a to 9d are made of a superconducting wire having an upper critical magnetic field of 14 Tesla or more, for example, an Nb3Sn superconducting wire.
- FIG. 2 is a schematic sectional view of the uniform magnetic field generator according to the present embodiment.
- the bobbin supporting each coil is not shown. Parts with the same reference numerals as those in Fig. 1 mean the same parts.
- the superconducting main coil groups 1 to 3 and the room temperature shim coil group 5 in addition to the first superconducting shim coil groups 4 a to 4 d installed outside the superconducting main coil groups 1 to 3, the superconducting main coil groups 1 to 3 and the room temperature shim coil group 5
- a second superconducting shim coil group 9a to 9d, and a third superconducting shim coil group 10a to 10d are provided.
- the coils constituting the second and third superconducting shim coil groups 9a to 9d and 10a to 10d are made of, for example, Nb3Sn superconducting wires.
- the distance from the central axis is different between the second superconducting shim coil groups 9a to 9d and the third superconducting shim coil groups 10a to 10d.
- a magnetic field component of a desired order can be efficiently generated.
- at least one of the superconducting shim coil groups 9a to 9d and 10a to 10d simultaneously generates magnetic field components of multiple orders, and independently controls the current value applied to each coil. Then, multiple order magnetic field components can be corrected simultaneously.
- FIG. 3 is a schematic sectional view of the uniform magnetic field generator according to the present embodiment. As in FIG. 2, the bobbin supporting each coil is not shown. The same reference numerals as those in FIG. 2 indicate the same parts.
- superconducting shim coil groups 9 a to 9 d and 10 a to 10 d are provided between superconducting main coil groups 1 to 3 and room temperature shim coil group 5.
- FIG. 4 is a schematic sectional view of the uniform magnetic field generator according to the present embodiment. As in FIG. 3, the bobbin supporting each coil is not shown. The same reference numerals as those in FIG. 3 indicate the same parts.
- the superconducting main coil group of the present embodiment is a so-called split type in which a first superconducting main coil group 1 a to 3 a and a second superconducting main coil group 1 b to 3 b are opposed via a gap. . Accordingly, the normal temperature shim coil groups 5a and 5b are also bisected in the axial direction.
- the first superconducting shim coil groups 4a to 4d and the superconducting main coil groups 1a to 3a and lb to 3b A second superconducting shim coil group 9a to 9d and a third superconducting shim coil group 10a to 10d are provided between the normal temperature shim coil groups 5a and 5b, respectively.
- the coils constituting the second and third superconducting shim coil groups 9a to 9d and 10a to 10d are made of, for example, Nb3Sn superconducting wires. Further, by supplying a current to a plurality of superconducting shim coils having different distances from the central axis, a magnetic field component of a desired order can be efficiently generated. Furthermore, at least one coil of the superconducting shim coil groups 9a to 9d and 10a to 10d simultaneously generates magnetic fields of a plurality of orders, and the current value supplied to each coil can be controlled independently. If this is the case, multiple orders of magnetic field components can be corrected simultaneously.
- FIG. 5 is a schematic sectional view of the uniform magnetic field generator according to the present embodiment. As in FIG. 4, the bobbin supporting each coil is not shown. The same reference numerals as those in FIG. 1 indicate the same parts.
- the apparatus of Example 4 shown in FIG. 4 was placed horizontally, and the test tube 6 containing the sample was placed in the first superconducting main coil group 1 a to 3 a and the second superconducting main coil group. Insert through the gap between 1b and 3b.
- the probe 7 is inserted from a port provided near the central axis of the superconducting main coil groups 1a to 3a and lb to 3b.
- the probe 7 is provided with a highly sensitive solenoid type detection antenna 11. Others are the same as in Example 4, and the normal temperature shim coil groups 5a and 5b are divided into two in the axial direction.
- the first superconducting shim coil groups 4a-4d, the superconducting main coil groups 1a-3a, lb-3b and room temperature shim coils A second superconducting shim coil group 9a to 9d and a third superconducting shim coil group 10a to 10d are provided between the groups 5a and 5b, respectively.
- the coils constituting the second and third superconducting shim coil groups 9a to 9d and 10a to 10d are made of, for example, Nb3Sn superconducting wires. Also, by supplying a current to a plurality of superconducting shim coils 5a and 5b having different distances from the central axis, a magnetic field component of a desired order can be efficiently generated.
- At least one coil of the superconducting shim coil group simultaneously generates a plurality of orders of magnetic field components and independently controls a current value supplied to each coil, a plurality of orders of magnetic field components can be corrected simultaneously.
- a uniform magnetic field generator having a superconducting shim coil group having a high ability to correct a high-order magnetic field in the axial direction can be obtained, and can be applied to an NMR apparatus.
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Abstract
Applications Claiming Priority (2)
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JP2003-120237 | 2003-04-24 | ||
JP2003120237A JP2004325251A (ja) | 2003-04-24 | 2003-04-24 | 均一磁場発生装置およびそれを用いた核磁気共鳴装置 |
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WO2004095047A1 true WO2004095047A1 (fr) | 2004-11-04 |
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PCT/JP2004/005978 WO2004095047A1 (fr) | 2003-04-24 | 2004-04-26 | Dispositif de generation de champ magnetique uniforme et dispositif de resonance magnetique nucleaire mettant en oeuvre celui-ci |
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WO (1) | WO2004095047A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7830146B2 (en) | 2006-02-15 | 2010-11-09 | Hitachi, Ltd. | NMR solenoidal coil for RF field homogeneity |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2009139206A1 (fr) | 2008-05-14 | 2009-11-19 | コニカミノルタエムジー株式会社 | Contrôleur d’imagerie dynamique et système d’imagerie dynamique |
JP6138600B2 (ja) * | 2013-06-12 | 2017-05-31 | ジャパンスーパーコンダクタテクノロジー株式会社 | 磁場発生装置 |
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JPS62231645A (ja) * | 1986-01-29 | 1987-10-12 | フオスフオ−エナジエテイツクス・インコ−ポレイテツド | Nmr用均質性磁場形成装置、nmr分光装置およびnmr分光方法 |
JPH02246928A (ja) * | 1989-03-20 | 1990-10-02 | Toshiba Corp | 磁界発生装置 |
JPH08273923A (ja) * | 1995-03-30 | 1996-10-18 | Hitachi Ltd | Nmr分析計用超電導マグネット装置及びその運転方法 |
JP2001099904A (ja) * | 1999-08-27 | 2001-04-13 | Bruker Ag | Z2シムを備えたアクティブ・シールド超伝導磁石システム |
WO2001031358A1 (fr) * | 1999-10-26 | 2001-05-03 | Oxford Magnet Technology Limited | Aimant permettant un acces plus facile |
JP2001264402A (ja) * | 2000-03-17 | 2001-09-26 | National Institute For Materials Science | 高磁場均一度超電導磁石装置 |
WO2002049513A1 (fr) * | 2000-12-05 | 2002-06-27 | Hitachi, Ltd. | Aimant a champ magnetique a faible fuite et ensemble bobinage blinde |
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US3771055A (en) * | 1972-03-17 | 1973-11-06 | Varian Associates | Double nuclear magnetic resonance coil |
JPH04168386A (ja) * | 1990-10-31 | 1992-06-16 | Shimadzu Corp | 磁場補正用シムコイルとその製造方法 |
JPH07240310A (ja) * | 1994-03-01 | 1995-09-12 | Mitsubishi Electric Corp | 核磁気共鳴分析装置用超電導マグネット |
GB0007018D0 (en) * | 2000-03-22 | 2000-05-10 | Akguen Ali | Magnetic resonance imaging apparatus and method |
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- 2003-04-24 JP JP2003120237A patent/JP2004325251A/ja active Pending
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- 2004-04-26 WO PCT/JP2004/005978 patent/WO2004095047A1/fr active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS62231645A (ja) * | 1986-01-29 | 1987-10-12 | フオスフオ−エナジエテイツクス・インコ−ポレイテツド | Nmr用均質性磁場形成装置、nmr分光装置およびnmr分光方法 |
JPH02246928A (ja) * | 1989-03-20 | 1990-10-02 | Toshiba Corp | 磁界発生装置 |
JPH08273923A (ja) * | 1995-03-30 | 1996-10-18 | Hitachi Ltd | Nmr分析計用超電導マグネット装置及びその運転方法 |
JP2001099904A (ja) * | 1999-08-27 | 2001-04-13 | Bruker Ag | Z2シムを備えたアクティブ・シールド超伝導磁石システム |
WO2001031358A1 (fr) * | 1999-10-26 | 2001-05-03 | Oxford Magnet Technology Limited | Aimant permettant un acces plus facile |
JP2001264402A (ja) * | 2000-03-17 | 2001-09-26 | National Institute For Materials Science | 高磁場均一度超電導磁石装置 |
WO2002049513A1 (fr) * | 2000-12-05 | 2002-06-27 | Hitachi, Ltd. | Aimant a champ magnetique a faible fuite et ensemble bobinage blinde |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7830146B2 (en) | 2006-02-15 | 2010-11-09 | Hitachi, Ltd. | NMR solenoidal coil for RF field homogeneity |
US8040136B2 (en) | 2006-02-15 | 2011-10-18 | Hitachi, Ltd. | NMR solenoidal coil for RF field homogeneity |
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