WO2003084602B1 - Vorrichtung zur förderung des knochenwachstums, insbesondere zur osteosynthese von knochenfragmenten und/oder fixation von knochenfrakturen - Google Patents

Vorrichtung zur förderung des knochenwachstums, insbesondere zur osteosynthese von knochenfragmenten und/oder fixation von knochenfrakturen

Info

Publication number
WO2003084602B1
WO2003084602B1 PCT/EP2003/003690 EP0303690W WO03084602B1 WO 2003084602 B1 WO2003084602 B1 WO 2003084602B1 EP 0303690 W EP0303690 W EP 0303690W WO 03084602 B1 WO03084602 B1 WO 03084602B1
Authority
WO
WIPO (PCT)
Prior art keywords
bone
implant
piezoelectric element
piezoelectric
pole
Prior art date
Application number
PCT/EP2003/003690
Other languages
English (en)
French (fr)
Other versions
WO2003084602A3 (de
WO2003084602A2 (de
Inventor
Ferdinand Gundolf
Original Assignee
Ferdinand Gundolf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferdinand Gundolf filed Critical Ferdinand Gundolf
Priority to EP03722435A priority Critical patent/EP1492591B1/de
Priority to US10/511,116 priority patent/US20050228503A1/en
Priority to DE50310864T priority patent/DE50310864D1/de
Priority to AU2003229633A priority patent/AU2003229633A1/en
Publication of WO2003084602A2 publication Critical patent/WO2003084602A2/de
Publication of WO2003084602A3 publication Critical patent/WO2003084602A3/de
Publication of WO2003084602B1 publication Critical patent/WO2003084602B1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/74—Devices for the head or neck or trochanter of the femur
    • A61B17/742—Devices for the head or neck or trochanter of the femur having one or more longitudinal elements oriented along or parallel to the axis of the neck
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/82—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin for bone cerclage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0003—Not used, see subgroups
    • A61C8/0004—Consolidating natural teeth
    • A61C8/0006—Periodontal tissue or bone regeneration
    • A61C8/0007—Stimulation of growth around implant by electrical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/809—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with bone-penetrating elements, e.g. blades or prongs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/34—Acetabular cups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/38—Joints for elbows or knees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2821—Bone stimulation by electromagnetic fields or electric current for enhancing ossification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30087—Properties of materials and coating materials piezoelectric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Vorrichtung zur Förderung von Knochenwachstum, insbesondere zur Osteosynthese von Knochenfragmenten und/oder Fixation von Knochenfrakturen, welche zumindest ein einem Implantat (10) od. dgl, Knochenfixiermittel zugeordnetes piezo-elektrisches Element (18) umfasst, das unter der Einwirkung von Kräften elektrische Impulse erzeugt, die als Stimulans für das Knochenwachstum dienen. Das wenigstens eine piezo-eletkrische Element (18) ist integraler Bestandteil des Implantats (10).

Claims

GEÄNDERTE ANSPRÜCHE[beim Internationalen Büro am 02 Dezember 2003 (02.12.03) eingegangen; ursprüngliche Ansprüche 1-11 durch geänderte Ansprüche 1-10 ersetzt (3 Seiten)](Neue) Patentansprüche
1. Vorrichtung zur Förderung von Knochenwachstum, insbesondere zur Osteosynthese von Knochenfragmenten und/oder Fixation von Knochenfrakturen, welche zumindest ein einem Implantat (10; 21; 25; 37; 38; 39) od. dgl. Knochenfixiermittel (49) zugeordnetes piezo-elektrisches Element
(18; 20; 29; 33; 34; 45; 46; 54) umfasst, das unter der Einwirkung von Kräften elektrische Impulse erzeugt, die als Stimulans für das Knochenwachstum dienen, d a d u rch g e ke n n zei c h n et, daß das wenigstens eine piezo-elektrische Element (18; ...54) innerhalb des
Implantats (10; ...39 bzw.49) integraler Bestandteil desselben ist, und dass das Implantat (10; ...) den einen Pol, insbesondere Minuspol, und ein nur mit umliegenden Knochen in Berührung kommendes Kontaktelement (19; 24; 30; 35; 36; 47; 48; 55) aus humanverträglichem, elektrisch leitendem, insbesondere metallischen Werkstoff den anderen Pol, insbesondere Pluspol des piezoelektrischen Elements (18; ...) definiert.
2. Vorrichtung nach Anspruch 1, d a d u rc h g e ke n n ze i ch n et, daß das Implantat (10; ...39 bzw.49) zumindest teilweise aus einer piezoelektrischen Keramik besteht.
3. Vorrichtung nach Anspruch 1 oder 2, d a d u rc h g e ke n n zei ch n et, daß 19
das piezo-elektrische Element (33; 34) innerhalb einer zum Knochen hin offenen Implantattasche (31; 32) angeordnet ist, insbesondere derart, daß es im wesentlichen bündig mit der Implantatoberfläche abschließt.
Vorrichtung nach einem der Ansprüche 1 bis 3, d a d u rc h g e ke n n z e i c h net, daß das Implantat (10; 21; 43; 44) nach Art eines Dübels ausgebildet ist, in dessen zentralem Hohlraum (17) das piezo-elektrische Element (18; 20; 45; 46) platziert ist.
5. Vorrichtung nach Anspruch 4, d a d u rc h g e ke n n ze i ch net, daß das Implantat eine stiftartige Halterung für einen künstlichen Zahn (11), eine Knochen- oder Pedikelschraube (13; 43; 44) oder ein Knochenfixierstift (21) od. dgl. Knochenfixierelement (49) ist.
6. Vorrichtung nach einem der Ansprüche 1 bis 3, d a d u rc h g e ke n nze i ch n e , daß das Implantat eine Hüftgelenkpfanne (25) mit wenigstens einer Bodenöffnung (28) ist, wobei innerhalb dieser das piezo-elektrische Element (29) platzierbar ist.
7. Vorrichtung nach Anspruch 6, d a d u rc h g e ke n nze i ch n et, daß das innerhalb der Bodenöffnung (28) angeordnete und diese ausfüllende piezoelektrische Element (29) mit einer sich über zumindest einen Teil der Innenseite des Pfannenbodens erstreckenden piezo-elektrischen Schicht (29) integral verbunden ist.
8. Vorrichtung nach einem der Ansprüche 1 bis 7, d a d u rc h g e ke n nze i ch n et, daß 20
das piezo-elektrische Element derart ausgebildet ist, daß bei üblicher Belastung der Knochenstruktur ein Strom mit einer effektiven Stromstärke von etwa 10- 100 μA erzeugbar ist.
9. Vorrichtung nach einem der Ansprüche 1 bis 8, da d u rch geken nzeich net, daß das piezo-elektrische Element aus einer piezo-elektrischen Keramik, insbesondere einer Zirkonat- oder Titanat-Keramik hergestellt ist.
10. Vorrichtung nach einem der Ansprüche 1 bis 9, d a d u rch g e ken n zei ch net, daß bei mindestens zwei piezo-elektrischen Elementen diese entweder elektrisch in Reihe oder elektrisch parallel geschaltet sind.
PCT/EP2003/003690 2002-04-11 2003-04-09 Vorrichtung zur förderung des knochenwachstums, insbesondere zur osteosynthese von knochenfragmenten und/oder fixation von knochenfrakturen WO2003084602A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP03722435A EP1492591B1 (de) 2002-04-11 2003-04-09 Vorrichtung zur förderung des knochenwachstums, insbesondere zur osteosynthese von knochenfragmenten und/oder fixation von knochenfrakturen
US10/511,116 US20050228503A1 (en) 2002-04-11 2003-04-09 Device for stimulating bone growth, especially for the osteosynthesis of bone fragments and/or for fixing bone fractures
DE50310864T DE50310864D1 (de) 2002-04-11 2003-04-09 Vorrichtung zur förderung des knochenwachstums, insbesondere zur osteosynthese von knochenfragmenten und/oder fixation von knochenfrakturen
AU2003229633A AU2003229633A1 (en) 2002-04-11 2003-04-09 Device for stimulating bone growth, especially for the osteosynthesis of bone fragments and/or for fixing bone fractures

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10215996A DE10215996B4 (de) 2002-04-11 2002-04-11 Vorrichtung zur Förderung des Knochenwachstums, insbesondere zur Osteosynthese von Knochenfragmenten und/oder Fixation von Knochenfrakturen
DE10215996.3 2002-04-11

Publications (3)

Publication Number Publication Date
WO2003084602A2 WO2003084602A2 (de) 2003-10-16
WO2003084602A3 WO2003084602A3 (de) 2004-02-05
WO2003084602B1 true WO2003084602B1 (de) 2004-03-11

Family

ID=28684949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/003690 WO2003084602A2 (de) 2002-04-11 2003-04-09 Vorrichtung zur förderung des knochenwachstums, insbesondere zur osteosynthese von knochenfragmenten und/oder fixation von knochenfrakturen

Country Status (6)

Country Link
US (1) US20050228503A1 (de)
EP (1) EP1492591B1 (de)
AT (1) ATE416006T1 (de)
AU (1) AU2003229633A1 (de)
DE (2) DE10215996B4 (de)
WO (1) WO2003084602A2 (de)

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WO2003084602A3 (de) 2004-02-05
DE10215996A1 (de) 2003-11-27
AU2003229633A8 (en) 2003-10-20
ATE416006T1 (de) 2008-12-15
EP1492591A2 (de) 2005-01-05
EP1492591B1 (de) 2008-12-03
DE50310864D1 (de) 2009-01-15
DE10215996B4 (de) 2005-07-21
WO2003084602A2 (de) 2003-10-16
AU2003229633A1 (en) 2003-10-20
US20050228503A1 (en) 2005-10-13

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