Formulation
This invention relates to novel skin care product formulations for topical application containing homeopathic quantities of plant extracts that enhance the skins natural repair processes.
The inevitable ageing process of the skin, normally initiated around the age of 30, is characterised by the thinning and wrinkling of the epidermis, combined with the appearance of lines, creases, furrows and age spots. The process is associated with a reduction in the skins' ability to repair and regenerate itself, the gradual breakdown collagen and elastin in the dermal layer, fat loss and the malfunctioning of melanocytes. A number of intrinsic and extrinsic factors contribute to this ageing process. Intrinsic factors include alterations in the body's hormonal balance, whilst the extrinsic factors include the long-term exposure to ultraviolet light and the accumulation of free radicals within the skin.
A plethora of skin care products are known in the art which claim to be able to repair, renew and revitalise ageing skin. Many of these products contain antioxidants, such vitamins A, C and E, which neutralise the effects of free radicals. A number of these skin care products also comprise plant extracts, however the levels of the active components are considered herbal rather than homeopathic. For example, a skin cream composition manufactured by Chanel Inc. (US patent No. 5922331) contains both calendula and aloe vera at a herbal level of 0.2% w/w of the composition, whilst homeopathic levels are considered to be at least 10-fold less. Whereas a homeopathic composition can be defined as containing minute doses of active natural drugs/substances, a herbal composition can be defined as consisting of, or made with aromatic herbs.
Likewise, a cosmetic and dermatological composition for psoriatic skin, scalp treatment and care, described in WO0166079, contains herbal rather than homeopathic levels of plant extracts, ranging from about 0.1 to about 10 % by weight
of aqueous-alcoholicglyceric extract of the mixture comprising nettle, chelidonia, oak bark, willow bark, calendula, dandelion root, camomile, achillea, dill and parsley.
A further patent, US5723138, provides an adhesive type cosmetic product for removing wrinkles prepared by coating 5-50 parts by weight of the composition comprising 5-40% by weight of vitamin E, 5-50% by weight of vitamin A and 15- 60%) by weight of concentrated natural aloe extract, and 50-95 parts by weight of an adhesive in a mixture or in a laminate structure on a carrier film
Homeopathic dilutions are often so extreme that they are dismissed by critics as being only a placebo effect. The "doses minimae" or indeed the 'law of infinitesimality', describes the fact that the remedy is given in infinitesimal doses, thereby reducing the remedy's toxicity whilst causing it to act in reverse. The principle of preparation of infinitesimal dilutions was described in Organon, and has changed little, even though it is applied industrially today. Each dilution is a hundredth of the previous one, and is called the first, fourth, thirtieth, or hundredth dilution, depending on the serial order. It is from this process that the name "Hahnemann's centesimal" originates.
According to a first aspect of the invention, we provide a skin care product for topical application comprising at least one plant extract present at homeopathic levels.
Preferably, the plant extract is a component of a homeopathic mix, wherein said homeopathic mix constitutes less than 1%> w/w of the total composition.
More preferably, said homeopathic mix constitutes between 0.25%> and 0.5% w/w of the total composition.
More preferably still, said homeopathic mix constitutes 0.38% w/w of the total composition.
Preferably the level of the plant extract is in the range from 0.0001 % - 0.1% w/w of said homeopathic mix.
Any conventionally known plant extracts may be used, for example, any homeopathic plant extracts.
In a preferred embodiment of this invention, the plant extracts are selected from the group consisting of; calendula spp, aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp.
More preferably still, the plant extracts are selected from the group consisting of; calendula officianalis, aloe barbadensis, thuya occidentalis, viola tricolor, camphor, hamamelis Virginia, vinca minor, articum lappa and nerium oleander.
The plant extracts have been derived from a number of sources that have already proven and defined homeopathic properties.
Calendula (calendula officianalis) with the common name of Marigold is a herbaceous annual with yellow petals. It is a member of the Compositae family and is native to Europe and naturalized in the United States. The Calendula plant contains essential oils, carotenoids, calenduline, lycopene, saponins, and resins. Calendula's useage is mostly topical in ointments or cremes for skin rashes, abrasions, minor burns, and eczemic conditions.
There are over 200 different species of Aloe, but of these only four are recognized as being of nutritional value to humans and animals. Aloe barbadensis, with the common names of Aloe Vera or Burn plant Aloe is a stemless, stoloniferous, clump- forming plant the medicinal properties of which have been known for some 3500 years ago. The plant was widely used by the Chinese, Egyptians, Greeks and Romans for healing skin-associated problems such as wounds, rashes, skin irritations, sunburns but also for headaches and stomach complaints. The medicinal properties
are found in the resinous sap or yellow juice of the leaves, which contains a mixture of phenolic compounds and polysaccharides, considered to have a soothing and anti- inflammatory effect, which has led them to be used in different cosmetic creams and moisturizers as well as shampoos.
Thuya Occidentalis with the common name of Cedar Leaf is characterised by its medicinal properties of being an antiseptic, astringent, emollient, expectorant, fungicide, insecticide, sedative, and tonic. It has been shown that chronic conditions such as dermatitis or psoriasis can be diminished, as well as seborrhea of the scalp, dandruff and alopecia.
Arctium lappa having the common name of Burdock is considered as a remedy for eczema, psoriasis, dandruff, rheumatic complaints and cystitis.
Viola tricolor having the common name of violet contains; saponins, salicylates, alkaloids, flavonoids, tannins and mucilage (a plant exude containing protein and carbohydrates), and has been widely used for the treatment of eczema, rashes, psoriasis, acne, skin irritations and itching.
Camphor is a white crystalline substance obtained from the evergreen tree Cinnamonum camphor a. Camphor has a strong, penetrating, fragrant odour, a bitter pungent taste and is slightly cold to the touch like menthol leaves. Camphor is often used internally for its calming influence in hysteria, nervousness, neuralgia and diarrhoea and externally as a counter-irritant in rheumatisms, sprains, bronchitis, and inflammatory conditions.
Vinca minor is commonly referred tcfas 'the lesser or dwarf periwinkle,' its actions relating to the skin include being analgesic, anti-bacterial, anti-microbial, anti- inflammatory, and an astrigent.
Hamamelis virginiana is commonly referred to as witch hazel and it contains varying amounts of active compounds such as flavonoids, tannins (hamamelitannin and proanthocyanidins), small amounts of volatile oil, and other components, which may be responsible for its astringent action.
The evergreen shrub Nerium Oleander or commonly called Rose Laurel or Oleander contains the ingredients oleandrin and nerioside. These ingredients are highly toxic at herbal levels but homeopathically are used to treat itching, bleeding and/or chapped skin.
In a preferred embodiment of the invention, a skin product is provided, wherein said skin product is a cleansing balm, and said cleansing balm contains calendula officinalis and at least one other plant extract selected from the group consisting of; aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably, the cleansing balm contains calendula officinalis and at least one other plant extract from the group consisting of; aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably still, the cleansing balm contains calendula officinalis and thuya occidentalis at 0.01% and 0.0001% w/w respectively of said homeopathic mix.
In a second preferred embodiment of the invention, a skin product is provided, wherein said skin product is a face mask, and said face mask contains thuya occidentalis and at least one other plant extract selected from the group consisting of; aloe spp, calendula spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001- 0.1% w/w of said homeopathic mix.
More preferably, the face mask contains thuya occidentalis and at least one other plant extract from the group consisting of; aloe barbadensis, calendula officinalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably still, the face mask contains thuya occidentalis and camphor at 0.0001%) and 0.01% w/w respectively of said homeopathic mix.
In a third preferred embodiment of the invention, a skin product is provided, wherein the skin product is a purifying wipe, and said purifying wipe is a tissue impregnated with extracts of calendula officinalis and at least one other plant extract selected from the group consisting of; aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably, the purifying wipe is a tissue impregnated with calendula officinalis and at least one other plant extract from the group consisting of; aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably still, the purifying wipe is a tissue impregnated with calendula officinalis and aloe barbadensis both at 0.01% w/w of said homeopathic mix.
In a fourth preferred embodiment of the invention, a skin product is provided, wherein said skin product is a moisturiser for oily skin for use in the mornings, and said moisturiser contains extracts of calendula officinalis and at least one other plant extract selected from the group consisting of; aloe spp, thuya spp, articum spp, viola
spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably, the moisturiser contains calendula officinalis and at least one other plant extract from the group consisting of; aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably still, the moisturiser contains calendula officinalis and articum lappa both at 0.01% w/w of said homeopathic mix.
In a fifth preferred embodiment of the invention, a skin product is provided, wherein said skin product is a moisturiser for oily skin for use in the evenings, and said moisturiser contains extracts of calendula officinalis and at least one other plant extract selected from the group consisting of; aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably, the moisturiser contains calendula officinalis and at least one other plant extract from the group consisting of; aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably still, the moisturiser contains calendula officinalis and articum lappa both at 0.01% w/w of said homeopathic mix.
In a sixth preferred embodiment of the invention, a skin product is provided, wherein said skin product is a moisturiser for dry skin for use in the mornings, wherein said moisturiser contains extracts of at least one plant extract selected from the group
consisting of; calendula spp, aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably, the moisturiser contains at least one other plant extract from the group consisting of; calendula officinalis, aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably still, the moisturiser contains viola tricolor 0.001 %> w/w of said homeopathic mix.
In a seventh preferred embodiment of the invention, a skin product is provided, wherein said skin product is a moisturiser for dry skin for use in the evenings, wherein said moisturiser contains extracts of at least one plant extract selected from the group consisting of; calendula spp, aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably, said moisturiser contains at least one plant extract from the group consisting of; calendula officinalis, aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably still, the moisturiser contains calendula officinalis at 0.01% w/w of said homeopathic mix.
In an eighth preferred embodiment of the invention, a skin product is provided, wherein said skin product is an intensive therapy serum, wherein said serum contains
at least one plant extract selected from the group consisting of; calendula spp, aloe spp, thuya spp, articum spp, viola spp, hamamelis spp, vinca spp, articum spp, camphor spp and nerium spp, wherein said plant extracts are present at 0.001-0.1% w/w of said homeopathic mix.
More preferably, said serum contains at least one plant extract from the group consisting of; calendula officinalis, aloe barbadensis, thuya occidentalis, articum lappa, viola tricolor, hamamelis virginiana, vinca minor, camphor and nerium oleander, wherein said plant extracts are present at 0.001-0.1%) w/w of said homeopathic mix.
More preferably still, the serum contains articum lappa, hamamelis virginiana, vinca minor and nerium oleander at 0.01%, 0.01, 0.01 and 0.001% w/w respectively, of said homeopathic mix.
According to a second aspect of the invention, we provide the use of a homeopathic level of a plant extract in a skin care product for topical application comprising at least one plant extract present at homeopathic levels.
According to a third aspect of the invention, we provide a method of manufacture of a skin care product for topical application, wherein said skin care product comprises at least one plant extract present at homeopathic levels.
According to a fourth aspect of the invention, we provide a method of treatment, wherein skin care product comprising at least one plant extract at homeopathic levels is topically applied to the skin to treat the ageing process.
According to a fifth aspect of the invention, we provide a delivery device for the topical delivery of said skin care product to the skin.
Preferably this delivery device is a tissue impregnated with calendula spp and aloe spp at levels less than 0.1%w/w of the total homeopathic mix.
More preferably this delivery device is a tissue impregnated with calendula officinalis and aloe barbadensis at levels less than 0.01%w/w of the total homeopathic mix.
The invention will now be illustrated by way of example only.
EXAMPLE 1: SIMPLE EQUILIBRIUM PURIFYING WIPES
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
ATOOOO Aqua (100%) PURIFIED WATER 81 79000 AT0147 Butylene Glycol (100%) BUTANE-1.3-DIOL 3 00000
ATO627 Phenoxyethanol (62 5%), PHENONIP 0 60000 Methylparaben (20%), Butylparaben (5%), Ethylparaben (5%), Propylparaben (5%), Isobutylparaben (2 5%)
AT0513 Sodium Methylparaben (100%) NIPAGIN M SODIUM 0 20000 AT0294 Aqua (62 8%), EMULGADE CM 10 00000
Cetearyl Isononanoate (15%),
Ceteareth-20 (8%),
Cetearyl Alcohol (7%),
Glyceryl Stearate (3%),
Glycerin (3%),
Cetyl Palmitate (0 5%),
Ceteareth-12 (0 5%),
Benzoic Acid (0 2%)
ATO844 Aqua (94 89%), NON-ALCOHOLIC WITCH HAZEL 3 00000 Hamamelis Virginiana (5%), Methylparaben (0 1 1%)
ATO761 Sodium Citrate (100%) TR1SODIUM CITRATE 0 45000 ATO185 Citric Acid (100%) CITRIC ACID 0 05000 ΛT0553 Citrus Dulcis (46 9%) NATURAL CALM 149173 0 05000 Lavandula Hybπda (10%) Citrus Limonum (15%)
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
Citrus Aurantium Amara (3%) Pogostemon Cablin (3%) Litse Cubeba (3%) Citrus Aurantifoha (3%) Lavandula Angustifolia (1%) Pelargonium Graveolens (3%) Conandrum Sativum (3%) Salvia Sclarea (3%) Juniperus Virginia (3%) Myπstica Fragrans (0 5%) Citrus Nobihs (0 5%) Jasminium Grandiflorum (0 5%) Zingiber OfTicinalis (0 1 %) Cupressus Sempervirens (0 5%) OciiTium Basilicum (0 5%) Artemisia Vulgans (0 5%)
AT0196 Polysorbate 20 (100%) EUMULGIN SML20 / CRILLET 1 SUPER 0 50000 AT0373 Aqua (71 1798%), HOMOEOPATHIC MIX 3 0 36000 Alcohol (28 8%),
ΛT0373 Calendula Officinalis (0 01%), HOMOEOPATHIC MIX 3 0 36000 Aloe Barbadensis (0 01%), Calcium Sulfate (0 0001%), CI 77268 1 (0 0001%)
TOTAL 100.0000
EXAMPLE 2: SIMPLE EQUILIBRIUM WARMING FACE MASK
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
AT0147 Butylene Glycol (100%) BUTANE-l,3-DIOL 2439000 AT0133 Glyccπn (97%), ACTIPHYTE OF FENNEL GL 100P 200000 Foeniculum Vulgare (2%), Phenoxyethanol (1%)
AT0342 Glycerin (100%) PRICER1NE 9091 / GLYCERIN BP USP / 2300000 GLYCERIN (VEG) ATO129 Bιs-PEG/PPG-20/20 Dimethicone (100%) ABIL B8832 100000 ATO553 Citrus Dulcis (46 9%) NATURAL CALM 149173 005000 Lavandula Hybπda (10%) Citrus Limonum (15%) Citrus Aurantium Amara (3%) Pogostemon Cablin (3%) Litsea Cubeba (3%) Citrus Aurantifolia (3%) Lavandula Angustifolia (1%) Pelargonium Graveolens (3%) Coπandrum Sativum (3%) Salvia Sclarea (3%) Juniperus Virginia (3%) Myristica Fragrans (0 5%) Citrus Nobihs (0 5%) Jastninium Grandiflorum (0 5%) Zmgiber Officinalis (0 1%) Cupiessus Sempervirens (0 5%) Ocimum Basilicum (0 5%) Artemisia Vulgaπs (0 5%)
AT0372 Alcohol (99 9897%), HOMOEOPATHIC MIX 2 0 36000 Camphor (0 01%), C 1 77268 1 (00001%), Caldum Sulfate (0 0001%),
Tliuya Occidentalis (0 0001%),
ATO576 Kaolm (100%) OCHRE RED CLAY 0 20000 AT0522 Sodium Sihcoaluminate (100%) MOLECULAR SIEVE 3A POWDER 18 00000 AT0213 Co Starch Modified (100%) DRY-FLO AF PURE 6 00000 AT0421 Kaolin (100%) KAOLIN 2747 USP 20 00000 ATO809 Paraffinum Liquidum (89 9%), VERSAGEL M-1600 5 00000
Hydrogenated Butylene Ethylene Styrene Copolymer (5%), Hydrogenated Ethylene/Propylene/Styrene Copolymer (5%), BHT (0 1%)
TOTAL 100.0000
EXAMPLE 3: SIMPLE EQUILIBRIUM AM MOISTURISER FOR DRY SKIN
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE:
ATOOOO Aqua (100%) PURIFIED WATER 62 07250
ATO505 Methylparaben (100%) NIP AGIN M / METHYL PARABEN USP 0 20000
AT0544 Disodium EDTA (100%) VERSENE NA2 CRYSTALS / NERVANΛID BA2 0 10000 POWDER
1
AT0631 Propylene Glycol (100%) MONOPROPYLENE GLYCOL 3 00000
ΛTO640 Panthenol (75%), D-PANTHENOL 75W 0 35000
Aqua (25%)
ATO702 Sodium Chloπde (100%) SALT PDV 0 50000
AT01 17 Cetyl PEG PPG-10/1 Dimethicone (100%) ABIL EM90 2 00000
AT0459 Hydrogenated Castor Oil (100%) LIOVAC 1110 0 50000
ATO172 Cera Alba (100%) CERABEIL BLΛNCHIE No 1 0 50000
ATO171 Dicaprylyl Carbonate (100%) CETIOL CC 12 00000
ATO506 Propylparaben (100%) NIPASOL M / PROPYL PARABEN USP 0 10000
AT0224 Tocopheryl Acetate (100%) VITAMIN E ACETATE 0 25000
AT0717 Cyclomethicone (100%) DOW CORNING 344 FLUID 5 00000
ATO803 Octyl Tπazone (100%) UVINUL T-150 2 00000
ATO622 Butyl Methoxydibenzoylmethane (100%) PΛRSOL 1789 2 00000
AT0648 Ethylhexyl Methoxycinnamate (100%) PARSOL MCX / ESCALOL 557 / NEOHEL1PAN 3 00000
TYPE AV
ATO275 4-Methylbenzylιdene Camphor (100%) EUSOLEX 6300 / PARSOL 5000 3 00000
AT0143 2-Bromo-2-Nιtropropane-l ,3-Dιol (100%) MYACIDE PHARMA BP / BRONOPOL 0 03000
AT0321 Terminaha Catappa Leaf Extract (51%), FIRMIDERM LS 9120 2 00000
Propylene Glycol (33%),
Sambucus Nigra Flower Extract (12 8%),
PVP (1%),
Tanπic Acid (1%),
Phenoxyethanol (1 2%)
ΛT0137 Aqua (32 9175%), BIO-PROT ECT 1 00000 Butylene Glycol (30%), Pyrus Malus (7 5%), Prunus Persica (7 5%), Iπticum Vulgare (5%), Hord'eum Vulgare (5%), Panax Ginseng (10%), Phenoxyethanol (0 4%), Methylparaben (0 4%), Butylparaben (0 4%), Ethylparaben (0 4%),
Propylparaben (0 4%),
Potassium Sorbate (0 08%),
Sodium Bisulfite (0 0025%)
PRODUCT INFORMATION PACK
EXAMPLE 3 CONTINUED:
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
ATO553 Citrus Dulcis (46 9%) NATURAL CALM 149173 0 03750 Lavandula Hybπda (10%) Citrus Limonum (15%) Citrus Aurantium Amara (3%) Pogostemon Cablin (3%) Litsea Cubeba (3%) Citrus Aurantifoha (3%) Lavandula Angustifolia (1%) Pelargonium Graveolens (3%) Coπandrum Sativum (3%) Salvia Sclarea (3%) Juniperus Virginia (3%) Myristica Fragrans (0 5%) Citrus Nobihs (0 5%) asmmium Grandiflorum (0 5%) Zmgiber Officinalis (0 1%) Cupressus Sempervirens (0 5%) Ocimum Basihcum (0 5%) Artemisia Vulgaπs (0 5%)
ATO376 Aqua (71 1976%) HOMOEOPATHIC MIX 6 0 36000 Alcohol (28 8%), Potassium Sulfate (0001%), Sodium Chloride (0 0001%), Silica (0 0001%), CI 77268 1 (0 0001%),
Viola Tricolor (0 001%), Petrolatum (0 0001%)
EXAMPLE 4: SIMPLE EQUILIBRIUM PM MOISTURISER FOR DRY SKIN
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE:
ATO000 Aqua (100%) PURIFIED WATER 6250250
ATO505 Methylparaben (100%) NIPAGIN M / METHYL PARABEN USP 020000
ATO342 Glycerin (100%) PRICERINE 9091 / GLYCERIN BP USP / 300000 GLYCERIN (VEG)
ATO640 Panthenol (75%), D-PANTHENOL 75W 135000 Aqua (25%)
ATO71 1 Sodium Hyaluronate (100%) SODIUM HYALURONATE 002000
ATOIOO Allantoin (100%) ALLANTOIN BPC1934 / ALLANTOIN BP 0 20000
AT0499 Magnesium Sulfate (50%), MAGNESIUM SULFATE HEPTAHYDRATE 0 70000 Aqua (50%)
AT0685 Isohexadecane (100%) PERMETHYL 101 A 500000
AT0264 Oclyldecanol (100%) EUTANOL G / ISOFOL 20 500000
AT0748 Cetearyl Isononanoate (100%) TEGOSOFT CI 500000
AT0223 Sorbitan Isostearate (60%), 2/015085 DRAGOSΛN W/OP 500000
Hydiogenated Castor Oil (15%), Cera Alba (15%), Polyglyceryl-3 Ricinoleate (7 5%), Caprylic/Capric Triglyceride (2 5%)
ATO717 Cyclomethicone (100%) DOW CORNING 344 FLUID 6 00000 ATO506 Propylparaben (100%) NIPASOL M / PROPYL PARABEN USP 0 10000 A10224 Tocopheryl Acetate (100%) VITAMIN E ACETATE 0 50000 ATO143 2-Bromo-2-Nιtropropane-l,3-Dιol (100%) MYACIDE PHΛRMA BP / BRONOPOL 0 03000 AT0321 lerminalia Catappa I-eaf Extract (51%), FIRMIDERM LS 9120 3 00000
Propylene Glycol (33%),
Sa bucus Nigra Flower Extract (12 8%),
PVP (1%),
Tanήic Acid (1%),
Phei yethanol (1 2%)
ΛTO296 Aqua (38 9%), 2/032861 EXTRAPONE GINSENG-SPECIAL 1 00000 Ethoxydiglycol (25%), Propylene Glycol (25%), Butylene Glycol (2 5%), Panax Ginseng (5%), Lactic Acid (2 5%), Glucose (0 2%), Citric Acid (0 2%), Sodium Benzoate (0 5%), Potassium Sorbate (0 2%)
ΛT0287 Aqua (96 02%), DRAGO-BETA-GLUCAN 1 00000 Butylene Glycol (1 1%), Glycerin (1 1%), Avena Sativa (1%),
AT0287 Potassium Sorbate (0 4%) DRAGO-BETA-GLUCAN 1 00000 Chlorphenesin (0 19%), Methylparaben (0 19%),
AT0553 Citrus Dulcis (46 9%) NATURAL CALM 149173 003750 Lavandula Hybπda (10%) Citrus Limonum (15%) Citrus Aurantium Amara (3%) Pogostemon Cablin (3%) Litsea Cubeba (3%)
EXAMPLE 4 CONTINUED.,..
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
Citrus Aurantifoha (3%) Lavandula Angustifolia (1%) Pelargonium Graveolens (3%) Coπandrum Sahvum (3%) Salvia Sclarea (3%) Jumperus Virginia (3%) Myπstica Fragrans (0 5%) Citrus NobΛs (0 5%) Jasmmium Grandiflorum (0 5%) Zmgiber Officinalis (0 1%) Cupressus Sεmpεrvirens (0 5%) Ocimum Basihcum (0 5%) Artemisia Vulgaπs (0 5%)
AT0377 Aqua (71 1888%), HOMOEOPATHIC MIX 7 0 36000 Alcςhol (28 8%), Calendula Officinalis (0 01%), Potassium Sulfate (0 001%), CI 77268 1 (00001%), Silica (0 0001%)
TOTAL 100.0000
EXAMPLE 5: SIMPLE EQUILIBRIUM AM MOISTURISER FOR OILY SKIN
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE:
A1O000 Aqua (100%) PURIFIED WATER 71 04750
AT0176 Carbomer (100%) CARBOPOL ETD 2001 0 20000
ATO505 Methylparaben (100%) NIPAGIN M / METHYL PARABEN USP 0 20000
EXAMPLE 5 CONTINUED....
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIALTRADE NAME: PERCENT: CODE:
A10544 Disodium ED fA (100%) VERSENE NA2 CRYSTALS / NERVANAID BA2 0 10000 POWDER
ATO767 Cetearyl Glucoside (100%) TEGOCARE CG90 1 00000
ATO205 Coco-Caprylate/Capiate (100%) CE1 lOL LC / WAGLINOL 20080 7 00000
ATO700 Dimethicone (100%) DOW CORNING 200/100CS FLUID 1 00000
A10224 Tocopheryl Acetate (100%) VITAMIN E ACE TAT E 0 25000
ATO680 Stearic Acid (100%) PRISTERENE 9559 0 60000
ATO462 Cetearyl Alcohol (100%) LΛUREX CS 0 60000
AT0622 Bu vl Methoxydibenzoylmethane (100%) PARSOL 1789 2 00000
AT0648 Ethylhexyl Methoxycinnamate (100%) PARSOL MCX / ESCALOL 557 / NEOHELIPAN 3 00000 TYPE ΛV
AT0689 Phytosphingosine (100%) PHYTOSPHINGOSINE 0 02000
AT0275 4-Methylbenzylιdene Camphor (100%) EUSOLEX 6300 / PARSOL 5000 3 00000
ATO803 θctγl Tπazone (100%) UVINUL T-150 2 00000
AT0712 Sodium Hydroxide (100%) CAUSTIC SODA PEARL 0 05500
AT0631 Propylene Glycol (100%) MONOPROPYLENE GLYCOL 3 00000
ATO578 Nylon-12 (100%) ORGASOL 2002 D NAT EXTRA COS 1 50000
ATO143 2-Bromo-2-Nιtτopropane-l ,3-Dιol (100%) MYACIDE PHARMA BP / BRONOPOL 0 03000
A10321 Terminalia Catappa Leaf Extract (51%), FIRMIDERM LS 9120 2 00000
Propylene Glycol (33%),
Sambucus Nigra Flower Extract (12 8%),
PVP (1%),
Tantnc Acιd (l%),
EXAMPLE 5 CONTINUED....
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
Phenoxyethanol (1 2%)
AT0137 Aqua (32 9175%), BIO-PROTECT 1 00000 Butylene Glycol (30%), Pyrus Malus (7 5%), Prunus Persica (7 5%), Tπticum Vulgare (5%), Hordeum Vulgare (5%), Panax Ginseng (10%), Phenoxyethanol (0 4%), Methylparaben (0 4%), Butylparaben (0 4%), Ethylparaben (0 4%), Propylparaben (0 4%), Potassium Sorbate (0 08%),
ATO137 Sodium Bisulfite (0 0025%) BIO-PROTEC r 1 00000 AT0553 Citrus Dulcis (46 9%) NATURAL CALM 149173 0 03750 Lavandula Hybπda (10%) Citius Limonum (15%) Citrus Aurantium Amara (3%) Pogostemon Cabhn (3%) Litsea Cubeba (3%) Citrus Aurantifolia (3%) Lavandula Angustifoha (1%) Pelargonium Graveolens (3%) Coπandrum Sativum (3%) Salvia Sclarea (3%) Juniperus Vuginia (3%) Myiislica Fragrans (0 5%) Citrus Nobihs (0 5%) Jastrunium Grandiflorum (0 5%) Zingiber Officinalis (0 1%) Cupressus Sempervirens (0 5%)
EXAMPLE 5 CONTINUED....
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
Ocimum Basihcum (0 5%) Artemisia Vulgaπs (0 5%)
AT0375 Aqua (71 1797%), HOMOEOPATHIC MIX 5 0 36000
Alcohol (28 8%), Calendula Officinalis (001%), Λrctium Lappa (0 01%), Calcium Sulfate (0 0001%),
Petrolatum (0 0001%) Silica (0 0001%)
TOTAL 100.0000
EXAMPLE 6: SIMPLE EQUILIBRIUM PM MOISTURISER FOR OILY SKIN
RAW MATERIAL INOl ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE: '
ATO000 Aqua (100%) PURIFIED WATER 75 58250
A1O170 Carbomer (100%) ULTREZ 10 0 80000
ATO640 Panthenol (75%), D-PANTHENOL 75W 1 00000
Aqua (25%)
ATO71 1 Sodium Hyaluronate (100%) SODIUM HYALURONATE 002000
ATO505 Methylparaben (100%) NIPAGIN M / METHYL PARABEN USP 020000
ATOIOO Allantoin (100%) ALLANTOIN BPC1934 / ALLANTOIN BP 020000
A10748 Cetearyl Isononanoate (100%) TEGOSOFT CI 300000
ΛTO126 Glyceryl Stearate (85%), ARLACEL 165 VS FLAKE 250000
EXAMPLE 6 CONTINUED.
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE:
PEG-100 Steaιate (15%)
AT0462 Cetearyl Alcohol (100%) LAUREX CS 1 50000
AT0689 Phyt-osphingosine (100%) PHYTOSPHINGOSTNE 0 02000
AT0224 Tocopheryl Acetate (100%) VITAMIN E ACETATE 0 50000
ΛTO551 Tetrahydroxypropyl Ethylenediamine (100%) NEUTROL TE 2 00000
AT0147 Butylene Glycol (100%) BUTANE- -DIOL 4 00000
AT0578 Nylon-12 (100%) ORGASOL 2002 D NA I EXTRA COS 2 00000
AT0143 2-Bromo-2-Nιtropropane-l ,3-Dιol (100%) MYACIDE PHARMΛ BP / BRONOPOL 0 03000
ΛT0321 Teπninalia Catappa Leaf Extract ( 1%), FIRMIDERM LS 9120 3 00000
Propylene Glycol (33%),
Sambucus Nigra Flower Extract (12 8%),
PVP (1 %),
Tannic Λcid (1 %),
Phenoxyethanol (1 2%)
AT0458 Aqua (47 85%), LΛCTIL 2 00000 Sodium Lactate (25%), Sodium PCA (25%), Sod.um Benzoate (0 65%), Glycine (0 25%), Fructose (0 25%), Urea (0 25%), Niacinamide (0 25%), Inositol (0 25%), Laclic Acid (0 25%)
ATO293 Propylene Glycol (50%), 2/032851 EX1RAPONE GINKGO BILOBA 1 00000 Aqua (37 5%), Gιnkgo Bιloba (10%), Lactic Acid (1 8%),
EXAMPLE 6 CONTINUED....
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE:
Potassium Sorbate (0 2%), Sodium Benzoate (0 5%)
ATO945 Zinc PCA (100%) ZINCIDONE 0 25000
AT0374 Aqua (71 1788%), HOMOEOPATHIC MIX 4 0 36000
10 Alcohol (28 8%), Calendula Officinalis (0 01%), Arctium Lappa (0 01%), Sodium Bicarbonate (0 001%),
-*ι Calcium Sulfate (0 0001%),
15 Silica (0 0001%)
AT0553 Citrus Dulcis (46 9%) NATURAL CALM 149173 003750 Lavandula Hybπda (10%) Citrus Limonum (15%) Citrus Aurantium Amara (3%)
20 Pogostemon Cablin (3%) Litsca Cubeba (3%) Citrus Aurantifolia (3%) Lavandula Λngustifoha (1 %) Pelaigonium Giaveolens (3%)
25 Coπandrum Sativum (3%) Salvia Sclarea (3%) Jumperus Virginia (3%) Myristica Fragrans (0 5%) Citrus Nobihs (0 5%)
30 lasminium Grandiflorum (0 5%) Zmgiber Officinalis (0 1%) Cupressus Sempervirens (0 5%)
Ocimtam Basilicum (0 5%) Artemisia Vulgaris (0 5%)
EXAMPLE 7: SIMPLE EQUILIBRIUM CLEANSING BALM
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
ATO461 Paraffinum Liquidum (100%) BLANDOL BP/USP / SIRIUS M85 WHITE / 6 29000 FINA VESTAN A80B
ATO809 Paraffinum Liquidum (89 9%), VERSAGEL M-1600 25 00000
Hydrogenated Butylene/Ethylene/Styrene Copolymer (5%), Hydrogenated Ethylene Propylene/Styrene Copolymer (5%), BHT (0 1%)
ATO707 Stearyl Alcohol (100%) HYFATOL 1895 / LOROL C 18/STEARYL 2 00000
ALCOHOL
AT0169 Petroleum Hydrocarbon (100%) CERAFTNE 56-58 20 00000
ATO154 C12-15 Alkyl Benzoate (100%) CRODAMOL AB / LINCOL BAS 4 00000
ΛTO840 Petrolatum (100%) WHITE PETROLEUM JELLY 895 / MERKUR 15 00000
584 WHITE PETROLEUM JELLY
AT0524 Limnanthes Alba (100%) MEADOWFOAM SEED OIL 1 00000
AT0748 Cetearyl Isononanoate (100%) TEGOSOFT CI 10 00000
AT0264 Octyjldecanol (100%) EUTΛNOL G / ISOFOL 20 10 00000
ΛT0213 Coπ> Starch Modified (100%) DRY-FLO AF PURE 1 00000
AT0627 Phenoxyethanol (62 5%), PHENONIP 0 30000
Methylparaben (20%),
EXAMPLE 7 CONTINUED.
I
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
Butylparaben (5%), Ethylparaben (5%), Propylparaben (5%), Isobutylparaben (2 5%)
AT0639 PEG-8 Dιlaurate (100%) PEG 400-DILAURATE 5 00000 AT0553 Citrus Dulcis (46 9%) NATURAL CALM 149173 0 05000 Lavandula Hybπda (10%) Citrus Limonum (15%) Citrus Λurantium Amara (3%) Pogostemon Cablin (3%) Litsea Cubeba (3%) Citius Aurantifoha (3%) Lavandula Λngustifoha (1%) Pelaigonium Graveolens (3%) Conandrum Sativum (3%) Salvia Sclarea (3%) Jumperus Virginia (3%) Myristica Fragrans (0 5%) Citrus Nobilis (0 5%) Jasminium Grandiflorum (0 5%) Zingiber Officinalis (0 1%) Cupressus Sempervirens (0 5%) Ocimum Basilicum (0 5%) Artemisia Vulgaris (0 5%)
ATO371 Alcohol (99 9898%), HOMOEOPATHIC MIX 1 0 36000 Calendula Officinalis (0 01%),
EXAMPLE 7 CONTINUED:
AT0371 Thuya Occidentalis (0 0001%), HOMOEOPATHIC MIX 1 0 36000 Calcium Sulfate (0 0001%)
EXAMPLE 8: SIMPLE EQUILIBRIUM INTENSIVE THERAPY SERUM
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT:
CODE:
A1O000 Aqu .'(100%) PURIFIED WATER 82 45750
AT0176 Carbomer (100%) CARBOPOL ETD 2001 0 30000
AT0147 Butylene Glycol (100%) BUTANE- 1 ,3-DIOL 3 00000
ATO640 Pantfieno! (75%), D-PANTHENOL 75W 1 30000
Aqua (25%)
ATO71 1 Sodium Hyaluronate (100%) SODIUM HYALURONATE 0 02000
ATO505 Methylparaben (100%) NIPAGIN M / METHYL PARABEN USP 0 10000
ATO100 Allantoin (100%) ALLANTOIN BPC1934 / ALLANTOIN BP 0 20000
AT0234 Divinyldimethicone/Dimethii DC HMW 2220 NON-IONIC EMULSION 5 00000
C12-13 Pareth-3 (l 5%), C12-l 3 Pareth-23 (2%),
EXAMPLE 8 CONTINUED:
Phenoxyethanol (1%),
Iodopropynyl Bulylcarbamate (0008%),
Aqua (34 492%)
A .0551 let. ahydroxypropyl Elhylεnediam e (100%) NEUTROLTE 0 50000 ATO804 Retinyl Palmitate (100%) VITAMIN A PALMITATE 0 10000 A10224 Tocopheryl Acetate (100%) VITAMIN E ACETAT E 0 50000 A10255 Bisabolol (100%) ALPHA-BISΛBOLOL - RAC / DRAOOSANTOL 0 10000 2/012681
A10321 ermmaha Catappa Leaf Extract (51 %), FIRMIDERM S 9120 200000
Propylene Glycol (33%),
Sambucus Nigra Flower Extract (1 8%),
PVP (1%),
Tanmc Acιd (l%),
Phenoxyethanol (1 2%)
A10727 Aqua (86 399%), SK-INFLUX 3 00000
Ceramιde 3 (l%),
Ceramide 6-H (0 5%),
Ceramide l (0001%),
Phytosphmgosme (0 5%),
Cholesterol (0 5%),
Sodium Lauroyl Lactylate (10%),
Carbomer (0 3%),
Xanthan Gum (0 3%),
Methylparaben (0 3%),
Propylparaben (0 2%)
AT0287 Aqua (9602%), DRAGO-BETA-GLUCAN 1 00000 Butylene Glycol (1 1%), Glycerin (1 1%), Avena Sattva (1%),
EXAMPLE 8 CONTINUED:
RAW MATERIAL INCI ADOPTED NAME: RAW MATERIAL TRADE NAME: PERCENT: CODE:
Potassium Sorbate (04%) Chlorphenesin (0 19%), Methylparaben (0 19%),
AT0553 Citrus Dulcis (46 9%) NATURAL CALM 149173 0 03750 Lavandula Hybnda (10%) Citrus Limonum (15%)
10 Citrus Aurantium Amara (3%) Pogostemon Cablm (3%) Litsea Cubeba (3%) Citrus Aurantifoha (3%>) Lavandula Angustifoha (1%)
° -5 Pelargonium Graveolens (3%) Coπandrum Salivum (3%) Salvia Sclarea (3%) Juniperus Virginia (3%) Myristica Fragrans (0 5%)
20 Citrus Nobihs (0 5%) Jasminium Grandiflorum (0 5%) Zingiber Officinalis (0 1%) Cupressus Sempervirens (0 5%) Ocimum Basilicum (0 5%)
25 Artemisia Vulgaris (0 5%)
ATO143 2-Bromo-2-Nιtropropane-l ,3-Dιol (100%) MYACIDE PHARMA BP / BRONOPOL 0 02500 AT0378 Aqua (71 1689%), HOMOEOPATHIC MIX 8 0 36000 Alcohol (28 8%), Hamamelis Virginiana (0 01%),
30 Vinca Minor (0 01%), Aictium Lappa (001%), Neπum Oleander (0 001%), Juglans Regia (0 0001%) P036544WO 2