WO2010012687A3 - Preparations based on artemisia annua, the conversion thereof into microparticles and nanoparticles, and use of same - Google Patents

Preparations based on artemisia annua, the conversion thereof into microparticles and nanoparticles, and use of same Download PDF

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Publication number
WO2010012687A3
WO2010012687A3 PCT/EP2009/059671 EP2009059671W WO2010012687A3 WO 2010012687 A3 WO2010012687 A3 WO 2010012687A3 EP 2009059671 W EP2009059671 W EP 2009059671W WO 2010012687 A3 WO2010012687 A3 WO 2010012687A3
Authority
WO
WIPO (PCT)
Prior art keywords
nanoparticles
artemisia annua
microparticles
conversion
preparations based
Prior art date
Application number
PCT/EP2009/059671
Other languages
German (de)
French (fr)
Other versions
WO2010012687A2 (en
Inventor
Wolf-Dieter Juelich
Hans-Peter Welzel
Ulrike Lindequist
Gerold Lukowski
Ottmar Geiger
Sabine Mundt
Original Assignee
Hc Berlin Pharma Ag
Ernst-Moritz-Arndt-Universität Greifswald
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hc Berlin Pharma Ag, Ernst-Moritz-Arndt-Universität Greifswald filed Critical Hc Berlin Pharma Ag
Priority to EP09781132A priority Critical patent/EP2320867A2/en
Publication of WO2010012687A2 publication Critical patent/WO2010012687A2/en
Publication of WO2010012687A3 publication Critical patent/WO2010012687A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706—Algae
    • A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Birds (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to preparations based on Artemisia annua, and to a plurality of methods for producing microparticles and nanoparticles from the annual mugwort (Artemisia annua). Ultrafine particles with improved properties are obtained as a result, that can be used as food supplements and feed supplements, in cosmetics and for medical purposes.
PCT/EP2009/059671 2008-07-26 2009-07-27 Preparations based on artemisia annua, the conversion thereof into microparticles and nanoparticles, and use of same WO2010012687A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09781132A EP2320867A2 (en) 2008-07-26 2009-07-27 Preparations based on artemisia annua, the conversion thereof into microparticles and nanoparticles, and use of same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008035442.2 2008-07-26
DE102008035442A DE102008035442A1 (en) 2008-07-26 2008-07-26 Preparations from Artemisia Annua, their transformation into micro- and nanoparticles and their use

Publications (2)

Publication Number Publication Date
WO2010012687A2 WO2010012687A2 (en) 2010-02-04
WO2010012687A3 true WO2010012687A3 (en) 2010-03-25

Family

ID=41428766

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/059671 WO2010012687A2 (en) 2008-07-26 2009-07-27 Preparations based on artemisia annua, the conversion thereof into microparticles and nanoparticles, and use of same

Country Status (3)

Country Link
EP (1) EP2320867A2 (en)
DE (1) DE102008035442A1 (en)
WO (1) WO2010012687A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018093150A2 (en) * 2016-11-15 2018-05-24 한국과학기술연구원 Composition containing artemisia annua extract as effective ingredient for alleviating skin disease and preparation method therefor
CN109646405A (en) * 2018-12-10 2019-04-19 江西赣隆药业有限公司 A kind of monkey mushroom granule and preparation method thereof
DE102020120218A1 (en) 2020-07-31 2022-02-03 KBHB Consult GmbH Molecules directed against the ribosomal protein rpL35/uL29 for use in the treatment of diseases, in particular epidermolysis bullosa (EB)
KR102590739B1 (en) * 2021-07-30 2023-10-17 강원대학교산학협력단 Selenium nanoparticles formed using Artemisia annua extract and encapsulated with starch and method for manufacturing the same

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952603A (en) * 1988-06-20 1990-08-28 Elferaly Farouk S Method for the isolation of artemisinin from Artemisia annua
WO2003072118A1 (en) * 2002-02-28 2003-09-04 Gerold Lukowski Micro/nanoparticle obtained from lipid-containing marine organisms for use in pharmaceutics and cosmetics
WO2003075862A2 (en) * 2002-03-08 2003-09-18 Accantia Holdings Limited Formulation
WO2004075907A2 (en) * 2003-02-27 2004-09-10 Ernst-Moritz-Arndt-Universität Greifswald Salutary compositions consisting of fungi containing lipids and thiocyanates
JP2006143711A (en) * 2004-10-22 2006-06-08 Taisho Pharmaceut Co Ltd Oral composition for ameliorating aging note
US20070269537A1 (en) * 2003-02-10 2007-11-22 Bioderm Research Skin Condition Improvement Including Acne, Rosacea, and Topical Wounds by Artemisia Annua Extract via Iron Siderophore Trojan Horse Delivery System

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JP2814085B2 (en) 1988-08-11 1998-10-22 株式会社資生堂 Hair restoration
FR2651680B1 (en) 1989-09-14 1991-12-27 Medgenix Group Sa NOVEL PROCESS FOR THE PREPARATION OF LIPID MICROPARTICLES.
US5250236A (en) 1991-08-05 1993-10-05 Gasco Maria R Method for producing solid lipid microspheres having a narrow size distribution
CN1047317C (en) 1993-01-01 1999-12-15 广东省翁源县青云山保健食品厂 Herb of linearstripe Rabdosia drink
CA2091152C (en) 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
DE19709649A1 (en) 1997-03-07 1998-09-24 Juelich Wolf Dieter Dipl Chem Measuring system for evaluating toxic or stimulating effect of active agents
IT1292142B1 (en) 1997-06-12 1999-01-25 Maria Rosa Gasco PHARMACEUTICAL COMPOSITION IN THE FORM OF SOLID LIPID MICROPARTICLES SUITABLE FOR PARENTERAL ADMINISTRATION
JP4280341B2 (en) 1998-11-09 2009-06-17 一丸ファルコス株式会社 Cosmetic composition containing moisturizing plant extract
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KR20040032288A (en) 2002-10-09 2004-04-17 서경석 Health food comprising natural Ganoderma Lucidum Karst components and method for the same
KR20030005127A (en) 2002-12-10 2003-01-15 황정규 Healthy foods on earth and alder
KR20030051517A (en) 2003-05-28 2003-06-25 서봉석 Health food using hovenia dulcis thunberg and semisulcospira libertina as main ingredient
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DE102005031363A1 (en) 2005-06-30 2007-01-18 Ernst-Moritz-Arndt-Universität Greifswald Agent with anti-aging effect, useful to prepare e.g. food supplements or fodder supplements, comprises extract containing effective components and/or a biomass from Ganoderma pipefferi
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Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952603A (en) * 1988-06-20 1990-08-28 Elferaly Farouk S Method for the isolation of artemisinin from Artemisia annua
WO2003072118A1 (en) * 2002-02-28 2003-09-04 Gerold Lukowski Micro/nanoparticle obtained from lipid-containing marine organisms for use in pharmaceutics and cosmetics
WO2003075862A2 (en) * 2002-03-08 2003-09-18 Accantia Holdings Limited Formulation
US20070269537A1 (en) * 2003-02-10 2007-11-22 Bioderm Research Skin Condition Improvement Including Acne, Rosacea, and Topical Wounds by Artemisia Annua Extract via Iron Siderophore Trojan Horse Delivery System
WO2004075907A2 (en) * 2003-02-27 2004-09-10 Ernst-Moritz-Arndt-Universität Greifswald Salutary compositions consisting of fungi containing lipids and thiocyanates
JP2006143711A (en) * 2004-10-22 2006-06-08 Taisho Pharmaceut Co Ltd Oral composition for ameliorating aging note

Also Published As

Publication number Publication date
WO2010012687A2 (en) 2010-02-04
EP2320867A2 (en) 2011-05-18
DE102008035442A1 (en) 2010-01-28

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