WO2003057215A1 - Accelerateur de production/secretion de facteur neurotrophique - Google Patents
Accelerateur de production/secretion de facteur neurotrophique Download PDFInfo
- Publication number
- WO2003057215A1 WO2003057215A1 PCT/JP2002/013654 JP0213654W WO03057215A1 WO 2003057215 A1 WO2003057215 A1 WO 2003057215A1 JP 0213654 W JP0213654 W JP 0213654W WO 03057215 A1 WO03057215 A1 WO 03057215A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optionally substituted
- neurotrophic factor
- factor production
- group
- secretion accelerator
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002367426A AU2002367426A1 (en) | 2001-12-28 | 2002-12-26 | Neurotrophic factor production/secretion accelerator |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001401380 | 2001-12-28 | ||
JP2001-401380 | 2001-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003057215A1 true WO2003057215A1 (fr) | 2003-07-17 |
Family
ID=19189767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/013654 WO2003057215A1 (fr) | 2001-12-28 | 2002-12-26 | Accelerateur de production/secretion de facteur neurotrophique |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002367426A1 (fr) |
WO (1) | WO2003057215A1 (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007502817A (ja) * | 2003-08-20 | 2007-02-15 | イーライ リリー アンド カンパニー | グルカゴン様ペプチド(glp)−1化合物またはメラノコルチン4受容体(mc4)アゴニストペプチドの経口デリバリーのための化合物、方法および製剤 |
US7470715B2 (en) | 2005-12-22 | 2008-12-30 | Pfizer Inc. | Estrogen modulators |
US8304438B2 (en) | 2006-12-20 | 2012-11-06 | Sanofi | Heteroarylacrylamides and their use as pharmaceuticals |
US8552039B2 (en) | 2003-08-20 | 2013-10-08 | Emisphere Technologies, Inc. | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP-1) compound or a melanocortin-4 receptor (MC4) agonist peptide |
US8604069B2 (en) | 2011-04-28 | 2013-12-10 | Japan Tobacco Inc. | Amide compound and medicinal use thereof |
CN113480489A (zh) * | 2021-08-19 | 2021-10-08 | 贵州大学 | 异噁唑联苯类化合物及其制备方法和应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0517354A (ja) * | 1991-07-03 | 1993-01-26 | Nichiban Co Ltd | イソキサゾ−ル誘導体含有経皮吸収製剤 |
JPH08175992A (ja) * | 1994-12-21 | 1996-07-09 | Sagami Chem Res Center | 神経成長因子産生促進剤および縮環型オキサゾール化合物 |
WO2001014372A2 (fr) * | 1999-08-25 | 2001-03-01 | Takeda Chemical Industries, Ltd. | Agent promoteur de la production/secretion de neurotrophine |
WO2002040458A1 (fr) * | 2000-11-17 | 2002-05-23 | Takeda Chemical Industries, Ltd. | Derives d'isoxazole |
JP2003081831A (ja) * | 2001-06-26 | 2003-03-19 | Takeda Chem Ind Ltd | TGF−βスーパーファミリー産生・分泌促進剤 |
-
2002
- 2002-12-26 WO PCT/JP2002/013654 patent/WO2003057215A1/fr active Application Filing
- 2002-12-26 AU AU2002367426A patent/AU2002367426A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0517354A (ja) * | 1991-07-03 | 1993-01-26 | Nichiban Co Ltd | イソキサゾ−ル誘導体含有経皮吸収製剤 |
JPH08175992A (ja) * | 1994-12-21 | 1996-07-09 | Sagami Chem Res Center | 神経成長因子産生促進剤および縮環型オキサゾール化合物 |
WO2001014372A2 (fr) * | 1999-08-25 | 2001-03-01 | Takeda Chemical Industries, Ltd. | Agent promoteur de la production/secretion de neurotrophine |
WO2002040458A1 (fr) * | 2000-11-17 | 2002-05-23 | Takeda Chemical Industries, Ltd. | Derives d'isoxazole |
JP2003081831A (ja) * | 2001-06-26 | 2003-03-19 | Takeda Chem Ind Ltd | TGF−βスーパーファミリー産生・分泌促進剤 |
Non-Patent Citations (5)
Title |
---|
BRAIN RESEARCH. MOLECULAR BRAIN RESEARCH, vol. 18, no. 3, 1993, pages 201 - 208 * |
DATABASE MEDLINE [online] "Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease", XP002965288, accession no. STN Database accession no. 1999167108 * |
DATABASE MEDLINE [online] "Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells", XP002965289, accession no. STN Database accession no. 93268074 * |
KATOH-SEMBA R. ET AL.: "Induction of brain-derived neurotrophic factor by convulsant drugs in the rat brain: involvement of region-specific voltage-dependent calcium channels", JOURNAL OF NEUROCHEMISTRY, vol. 77, no. 1, 2000, pages 71 - 83, XP002965287 * |
NEUROBIOLOGY OF DISEASE, vol. 5, no. 5, 1998, pages 357 - 364 * |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007502817A (ja) * | 2003-08-20 | 2007-02-15 | イーライ リリー アンド カンパニー | グルカゴン様ペプチド(glp)−1化合物またはメラノコルチン4受容体(mc4)アゴニストペプチドの経口デリバリーのための化合物、方法および製剤 |
US7947841B2 (en) | 2003-08-20 | 2011-05-24 | Emisphere Technologies, Inc. | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP)-1 compound or a melanocortin-4 receptor (MC4) agonist peptide |
JP4754487B2 (ja) * | 2003-08-20 | 2011-08-24 | エミスフィアー テクノロジーズ インコーポレイテッド | グルカゴン様ペプチド(glp)−1化合物またはメラノコルチン4受容体(mc4)アゴニストペプチドの経口デリバリーのための化合物、方法および製剤 |
US8546581B2 (en) | 2003-08-20 | 2013-10-01 | Emisphere Technologies, Inc. | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (Glp)-1 compound or a melanocortin-4 receptor (Mc4) agonist peptide |
US8552039B2 (en) | 2003-08-20 | 2013-10-08 | Emisphere Technologies, Inc. | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP-1) compound or a melanocortin-4 receptor (MC4) agonist peptide |
US8765796B2 (en) | 2003-08-20 | 2014-07-01 | Emisphere Technologies, Inc. | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP-1) compound or a melanocortin-4 receptor (MC4) agonist peptide |
US7470715B2 (en) | 2005-12-22 | 2008-12-30 | Pfizer Inc. | Estrogen modulators |
US8304438B2 (en) | 2006-12-20 | 2012-11-06 | Sanofi | Heteroarylacrylamides and their use as pharmaceuticals |
US8604069B2 (en) | 2011-04-28 | 2013-12-10 | Japan Tobacco Inc. | Amide compound and medicinal use thereof |
CN113480489A (zh) * | 2021-08-19 | 2021-10-08 | 贵州大学 | 异噁唑联苯类化合物及其制备方法和应用 |
Also Published As
Publication number | Publication date |
---|---|
AU2002367426A1 (en) | 2003-07-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU3461697A (en) | Heterocyclic compounds, their production and use | |
WO2002100812A1 (fr) | Dérivé de l'acide carboxylique et son sel | |
WO2004024777A8 (fr) | Derives d'amidon hydroxyalkyle | |
EP1394147A4 (fr) | Derive de l'acide carboxylique et medicament comprenant un sel ou un ester dudit derive | |
RS51444B (sr) | JEDINJENJA KOJA SADRŽE LAKTAM I NJIHOVI DERIVATI KAO INHIBITORI FAKTORA Xa | |
CA2173150A1 (fr) | Nouveau derive peptidique | |
CA2418770A1 (fr) | Compose acylacetonitrile, processus de preparation, et acaricide contenant ce compose | |
WO2003046034A3 (fr) | Synthese amelioree de polyanhyrides | |
EP1582521A4 (fr) | Compose de furane condense | |
WO1999009965A3 (fr) | Agent antiinflammatoire | |
EP1291344A4 (fr) | Agents de controle de la piriculariose du riz | |
WO2003035620A1 (fr) | Compose bicyclique | |
MXPA05013631A (es) | Derivado heterociclico de metilsulfona. | |
WO2003059907A1 (fr) | Composes heterocycliques azotes : procede de preparation et d'utilisation | |
WO2003004497A1 (fr) | Compose heterocyclique | |
IE901350L (en) | Diaminoethylene compounds | |
WO2002000638A3 (fr) | Nouveaux phthalides substitues, leur procede de preparation et compositions pharmaceutiques les contenant | |
WO2003057215A1 (fr) | Accelerateur de production/secretion de facteur neurotrophique | |
WO2003035650A1 (fr) | Inhibiteur d'entree | |
EP1550651A4 (fr) | Derive glycerol | |
DE60230781D1 (en) | Reverse hydroxamsäurederivate | |
EP1661898A4 (fr) | Compose de piperazine bicyclique et utilisation de ce dernier | |
EP1174421A4 (fr) | Derives de 3-amidinobenzenesulfonamide, compositions medicales qui les contiennent, et produits intermediaires pour leur elaboration | |
EP1346994A4 (fr) | Inhibiteurs de la biosynthese du cholesterol contenant comme principe actif des composes spiro tricycliques | |
EP1310490A4 (fr) | Antagoniste de gpr14 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
122 | Ep: pct application non-entry in european phase | ||
NENP | Non-entry into the national phase |
Ref country code: JP |