WO2003056324A3 - Titrationsverfahren - Google Patents
Titrationsverfahren Download PDFInfo
- Publication number
- WO2003056324A3 WO2003056324A3 PCT/EP2002/014060 EP0214060W WO03056324A3 WO 2003056324 A3 WO2003056324 A3 WO 2003056324A3 EP 0214060 W EP0214060 W EP 0214060W WO 03056324 A3 WO03056324 A3 WO 03056324A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- analyte
- reaction
- amount
- drop
- titration method
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
- B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
- B01F31/87—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations transmitting the vibratory energy by means of a fluid, e.g. by means of air shock waves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
- B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/3035—Micromixers using surface tension to mix, move or hold the fluids
- B01F33/30351—Micromixers using surface tension to mix, move or hold the fluids using hydrophilic/hydrophobic surfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
- G01N31/16—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using titration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/089—Virtual walls for guiding liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
- B01L2400/0436—Moving fluids with specific forces or mechanical means specific forces vibrational forces acoustic forces, e.g. surface acoustic waves [SAW]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0493—Specific techniques used
- B01L2400/0496—Travelling waves, e.g. in combination with electrical or acoustic forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002352241A AU2002352241A1 (en) | 2001-12-28 | 2002-12-11 | Titration method |
US10/501,501 US20050037507A1 (en) | 2001-12-28 | 2002-12-11 | Titration method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10164357.8 | 2001-12-28 | ||
DE10164357A DE10164357B4 (de) | 2001-12-28 | 2001-12-28 | Titrationsverfahren |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003056324A2 WO2003056324A2 (de) | 2003-07-10 |
WO2003056324A3 true WO2003056324A3 (de) | 2004-03-25 |
Family
ID=7711082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2002/014060 WO2003056324A2 (de) | 2001-12-28 | 2002-12-11 | Titrationsverfahren |
Country Status (4)
Country | Link |
---|---|
US (1) | US20050037507A1 (de) |
AU (1) | AU2002352241A1 (de) |
DE (1) | DE10164357B4 (de) |
WO (1) | WO2003056324A2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050037508A1 (en) * | 2003-08-12 | 2005-02-17 | Juan Hernandez | Microfluidic titration apparatus |
US20050226773A1 (en) * | 2004-04-01 | 2005-10-13 | Honeywell International, Inc. | Multiple modes acoustic wave sensor |
GB0420155D0 (en) * | 2004-09-10 | 2004-10-13 | Univ Cambridge Tech | Liquid mixing/reactor device and method |
DE102005000835B3 (de) * | 2005-01-05 | 2006-09-07 | Advalytix Ag | Verfahren und Vorrichtung zur Dosierung kleiner Flüssigkeitsmengen |
WO2006138543A1 (en) * | 2005-06-16 | 2006-12-28 | Core-Microsolutions, Inc. | Biosensor detection by means of droplet driving, agitation, and evaporation |
US20070047388A1 (en) * | 2005-08-25 | 2007-03-01 | Rockwell Scientific Licensing, Llc | Fluidic mixing structure, method for fabricating same, and mixing method |
DE102005050167B4 (de) * | 2005-10-19 | 2009-02-19 | Advalytix Ag | Konzentrationsverfahren, Konzentrationsvorrichtung und Reaktionsverfahren |
US9476856B2 (en) | 2006-04-13 | 2016-10-25 | Advanced Liquid Logic, Inc. | Droplet-based affinity assays |
US8613889B2 (en) * | 2006-04-13 | 2013-12-24 | Advanced Liquid Logic, Inc. | Droplet-based washing |
US8637317B2 (en) * | 2006-04-18 | 2014-01-28 | Advanced Liquid Logic, Inc. | Method of washing beads |
US8492168B2 (en) * | 2006-04-18 | 2013-07-23 | Advanced Liquid Logic Inc. | Droplet-based affinity assays |
US20140193807A1 (en) | 2006-04-18 | 2014-07-10 | Advanced Liquid Logic, Inc. | Bead manipulation techniques |
US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
US7901947B2 (en) | 2006-04-18 | 2011-03-08 | Advanced Liquid Logic, Inc. | Droplet-based particle sorting |
WO2007123908A2 (en) | 2006-04-18 | 2007-11-01 | Advanced Liquid Logic, Inc. | Droplet-based multiwell operations |
US8809068B2 (en) * | 2006-04-18 | 2014-08-19 | Advanced Liquid Logic, Inc. | Manipulation of beads in droplets and methods for manipulating droplets |
US10078078B2 (en) | 2006-04-18 | 2018-09-18 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
US7851184B2 (en) | 2006-04-18 | 2010-12-14 | Advanced Liquid Logic, Inc. | Droplet-based nucleic acid amplification method and apparatus |
US8637324B2 (en) * | 2006-04-18 | 2014-01-28 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
JP5159197B2 (ja) * | 2007-07-25 | 2013-03-06 | キヤノン株式会社 | 液体制御装置 |
US9103782B2 (en) | 2008-12-02 | 2015-08-11 | Malvern Instruments Incorporated | Automatic isothermal titration microcalorimeter apparatus and method of use |
US20120074961A1 (en) * | 2010-09-29 | 2012-03-29 | Kopin Corporation | Capacitive sensor with active shield electrode |
EP2665957B1 (de) | 2011-01-21 | 2015-03-11 | Fluimedix APS | Verfahren zur steuerung eines flusses |
WO2013009927A2 (en) | 2011-07-11 | 2013-01-17 | Advanced Liquid Logic, Inc. | Droplet actuators and techniques for droplet-based assays |
CN110314715B (zh) * | 2019-07-17 | 2020-07-10 | 西安交通大学 | 基于聚焦式表面声波和微液滴技术的粒子富集微流控芯片 |
CN113436776A (zh) * | 2021-05-24 | 2021-09-24 | 广东工业大学 | 一种液滴载体式微小物体定向移动方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3913632A1 (de) * | 1989-04-04 | 1990-10-25 | Mettler Toledo Ag | Titriergeraet |
DE19545130A1 (de) * | 1995-12-04 | 1997-06-05 | Karl Prof Dr Cammann | Verfahren und Vorrichtungen für ein modulares Mikrosystem für hochgenaue chemische Schnell-Analysen und Verfahren zur Herstellung |
DE19702621A1 (de) * | 1997-01-27 | 1998-07-30 | Wildanger Hans Joerg | Analyseautomat |
WO1999054730A1 (en) * | 1998-04-20 | 1999-10-28 | Wallac Oy | Method and device for carrying out a chemical analysis in small amounts of liquid |
DE10055318A1 (de) * | 2000-06-09 | 2001-12-20 | Advalytix Ag | Vorrichtung und Verfahren zum Materietransport kleiner Materiemengen |
DE10120035A1 (de) * | 2001-04-24 | 2002-11-14 | Advalytix Ag | Verfahren und Vorrichtung zur Manipulation kleiner Flüssigkeitsmengen auf Oberflächen |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8612221D0 (en) * | 1986-05-20 | 1986-06-25 | Amersham Int Plc | Assaying species in sample |
US6777245B2 (en) * | 2000-06-09 | 2004-08-17 | Advalytix Ag | Process for manipulation of small quantities of matter |
-
2001
- 2001-12-28 DE DE10164357A patent/DE10164357B4/de not_active Expired - Fee Related
-
2002
- 2002-12-11 AU AU2002352241A patent/AU2002352241A1/en not_active Abandoned
- 2002-12-11 US US10/501,501 patent/US20050037507A1/en not_active Abandoned
- 2002-12-11 WO PCT/EP2002/014060 patent/WO2003056324A2/de not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3913632A1 (de) * | 1989-04-04 | 1990-10-25 | Mettler Toledo Ag | Titriergeraet |
DE19545130A1 (de) * | 1995-12-04 | 1997-06-05 | Karl Prof Dr Cammann | Verfahren und Vorrichtungen für ein modulares Mikrosystem für hochgenaue chemische Schnell-Analysen und Verfahren zur Herstellung |
DE19702621A1 (de) * | 1997-01-27 | 1998-07-30 | Wildanger Hans Joerg | Analyseautomat |
WO1999054730A1 (en) * | 1998-04-20 | 1999-10-28 | Wallac Oy | Method and device for carrying out a chemical analysis in small amounts of liquid |
DE10055318A1 (de) * | 2000-06-09 | 2001-12-20 | Advalytix Ag | Vorrichtung und Verfahren zum Materietransport kleiner Materiemengen |
DE10120035A1 (de) * | 2001-04-24 | 2002-11-14 | Advalytix Ag | Verfahren und Vorrichtung zur Manipulation kleiner Flüssigkeitsmengen auf Oberflächen |
Also Published As
Publication number | Publication date |
---|---|
AU2002352241A1 (en) | 2003-07-15 |
DE10164357A1 (de) | 2003-07-10 |
DE10164357B4 (de) | 2005-11-10 |
WO2003056324A2 (de) | 2003-07-10 |
AU2002352241A8 (en) | 2003-07-15 |
US20050037507A1 (en) | 2005-02-17 |
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