WO2003018077A1 - Procede de regeneration osseuse - Google Patents
Procede de regeneration osseuse Download PDFInfo
- Publication number
- WO2003018077A1 WO2003018077A1 PCT/JP2002/008420 JP0208420W WO03018077A1 WO 2003018077 A1 WO2003018077 A1 WO 2003018077A1 JP 0208420 W JP0208420 W JP 0208420W WO 03018077 A1 WO03018077 A1 WO 03018077A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bone
- size
- regenerated
- transplantation therapy
- bone regeneration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3847—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02796177A EP1433487A1 (en) | 2001-08-22 | 2002-08-21 | Method of bone regeneration |
JP2003522592A JP4412537B2 (ja) | 2001-08-22 | 2002-08-21 | 骨の再生方法 |
US10/487,279 US20040241145A1 (en) | 2001-08-22 | 2002-08-21 | Method of bone regeneration |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001251365 | 2001-08-22 | ||
JP2001-251365 | 2001-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003018077A1 true WO2003018077A1 (fr) | 2003-03-06 |
Family
ID=19080022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/008420 WO2003018077A1 (fr) | 2001-08-22 | 2002-08-21 | Procede de regeneration osseuse |
Country Status (4)
Country | Link |
---|---|
US (1) | US20040241145A1 (ja) |
EP (1) | EP1433487A1 (ja) |
JP (1) | JP4412537B2 (ja) |
WO (1) | WO2003018077A1 (ja) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1727892A1 (en) * | 2004-03-22 | 2006-12-06 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
JP2007236450A (ja) * | 2006-03-06 | 2007-09-20 | Teijin Ltd | 培養人工骨 |
JP2007532211A (ja) * | 2004-04-15 | 2007-11-15 | ニクリス アーゲー | 骨形成マトリックス複合体、その製造方法および骨形成複合体マトリックスのコーティングを有する組織工学用のインプラントおよび骨組 |
JP2008307186A (ja) * | 2007-06-13 | 2008-12-25 | Univ Kurume | 顎骨の再生に使用する顎骨用移植材料及びその製造方法 |
JP2009508540A (ja) * | 2005-08-17 | 2009-03-05 | オックスフォード バイオマテリアリルズ リミテッド | 移植可能な軟骨組織修復デバイス |
JP2014108296A (ja) * | 2012-12-04 | 2014-06-12 | Yamagata Univ | 生体内分解吸収性繊維強化複合材料およびその製造方法 |
WO2017150371A1 (ja) * | 2016-02-29 | 2017-09-08 | 国立大学法人大阪大学 | 組織損傷治療剤 |
WO2018021333A1 (ja) * | 2016-07-25 | 2018-02-01 | 宇部興産株式会社 | 骨損傷部位の治療のためのインプラント及びキット、並びに骨損傷部位の治療方法 |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1026712C2 (nl) * | 2004-07-23 | 2006-01-24 | Technologiestichting Stw | Bioresorbeerbaar botimplantaat. |
US20100150885A1 (en) * | 2005-06-01 | 2010-06-17 | Joslin Diabetes Center, Inc. | Methods and compositions for inducing brown adipogenesis |
WO2007034843A1 (ja) * | 2005-09-20 | 2007-03-29 | National Institute For Materials Science | 多孔質基盤体とその製造方法並びに多孔質基盤体の使用方法 |
US20110142810A1 (en) * | 2008-08-19 | 2011-06-16 | Osaka University | Cell preparation for bone tissue regeneration |
EP2543398B1 (en) * | 2010-03-02 | 2019-10-16 | FUJIFILM Corporation | Cell support and bone regeneration material |
WO2014093836A1 (en) * | 2012-12-13 | 2014-06-19 | University Of Georgia Research Foundation, Inc. | Ossification-inducing composition and methods of use thereof |
JP6358605B2 (ja) | 2015-01-26 | 2018-07-18 | 宇部興産株式会社 | 骨髄類似構造を利用した細胞培養法、及び骨損傷部位の治療のためのポリイミド多孔質膜 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0323864A (ja) * | 1989-06-20 | 1991-01-31 | Gunze Ltd | 生体組織用充填材 |
WO1998000180A1 (en) * | 1996-06-28 | 1998-01-08 | Johnson & Johnson Medical, Inc. | Use of oxidized cellulose and complexes thereof for chronic wound healing |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5700289A (en) * | 1995-10-20 | 1997-12-23 | North Shore University Hospital Research Corporation | Tissue-engineered bone repair using cultured periosteal cells |
EP0907721A1 (en) * | 1996-05-28 | 1999-04-14 | Brown University Research Foundation | Hyaluronan based biodegradable scaffolds for tissue repair |
-
2002
- 2002-08-21 WO PCT/JP2002/008420 patent/WO2003018077A1/ja active Application Filing
- 2002-08-21 JP JP2003522592A patent/JP4412537B2/ja not_active Expired - Lifetime
- 2002-08-21 US US10/487,279 patent/US20040241145A1/en not_active Abandoned
- 2002-08-21 EP EP02796177A patent/EP1433487A1/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0323864A (ja) * | 1989-06-20 | 1991-01-31 | Gunze Ltd | 生体組織用充填材 |
WO1998000180A1 (en) * | 1996-06-28 | 1998-01-08 | Johnson & Johnson Medical, Inc. | Use of oxidized cellulose and complexes thereof for chronic wound healing |
Non-Patent Citations (1)
Title |
---|
BRUDER S.P. ET AL.: "The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects", THE JOURNAL OF BONE AND JOINT SURGERY, vol. 80-A, no. 7, 1998, pages 985 - 996, XP002962310 * |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10960025B2 (en) | 2004-03-22 | 2021-03-30 | Mesoblast International Sárl | Mesenchymal stem cells and uses therefor |
US11389484B2 (en) | 2004-03-22 | 2022-07-19 | Mesoblast International Sárl | Mesenchymal stem cells and uses therefor |
US10668101B2 (en) | 2004-03-22 | 2020-06-02 | Mesoblast International Sárl | Mesenchymal stem cells and uses therefor |
US10729727B2 (en) | 2004-03-22 | 2020-08-04 | Mesoblast International Sárl | Mesenchymal stem cells and uses therefor |
EP1727892A1 (en) * | 2004-03-22 | 2006-12-06 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
US9943547B2 (en) | 2004-03-22 | 2018-04-17 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
EP1727892A4 (en) * | 2004-03-22 | 2007-08-22 | Osiris Therapeutics Inc | MESENCHYM STAMM CELLS AND USES FOR |
US9694035B2 (en) | 2004-03-22 | 2017-07-04 | Mesoblast International Sarl | Mesenchymal stem cells and uses therefor |
US10828334B1 (en) | 2004-03-22 | 2020-11-10 | Mesoblast International Sárl | Mesenchymal stem cells and uses therefor |
US10716814B2 (en) | 2004-03-22 | 2020-07-21 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
JP2007532211A (ja) * | 2004-04-15 | 2007-11-15 | ニクリス アーゲー | 骨形成マトリックス複合体、その製造方法および骨形成複合体マトリックスのコーティングを有する組織工学用のインプラントおよび骨組 |
US9226992B2 (en) | 2005-08-17 | 2016-01-05 | Orthox Limited | Implantable cartilaginous tissue repair device |
JP2009508540A (ja) * | 2005-08-17 | 2009-03-05 | オックスフォード バイオマテリアリルズ リミテッド | 移植可能な軟骨組織修復デバイス |
JP2007236450A (ja) * | 2006-03-06 | 2007-09-20 | Teijin Ltd | 培養人工骨 |
JP2008307186A (ja) * | 2007-06-13 | 2008-12-25 | Univ Kurume | 顎骨の再生に使用する顎骨用移植材料及びその製造方法 |
JP2014108296A (ja) * | 2012-12-04 | 2014-06-12 | Yamagata Univ | 生体内分解吸収性繊維強化複合材料およびその製造方法 |
WO2017150371A1 (ja) * | 2016-02-29 | 2017-09-08 | 国立大学法人大阪大学 | 組織損傷治療剤 |
JPWO2018021333A1 (ja) * | 2016-07-25 | 2019-05-16 | 宇部興産株式会社 | 骨損傷部位の治療のためのインプラント及びキット、並びに骨損傷部位の治療方法 |
WO2018021333A1 (ja) * | 2016-07-25 | 2018-02-01 | 宇部興産株式会社 | 骨損傷部位の治療のためのインプラント及びキット、並びに骨損傷部位の治療方法 |
Also Published As
Publication number | Publication date |
---|---|
US20040241145A1 (en) | 2004-12-02 |
JPWO2003018077A1 (ja) | 2004-12-09 |
EP1433487A1 (en) | 2004-06-30 |
JP4412537B2 (ja) | 2010-02-10 |
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