WO2002096805A3 - Separation von komponenten einer analysenprobe in einem ionenmobilitätsspektrometer durch zuführung selektiv wechselwirkender gasförmiger partikel - Google Patents

Separation von komponenten einer analysenprobe in einem ionenmobilitätsspektrometer durch zuführung selektiv wechselwirkender gasförmiger partikel Download PDF

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Publication number
WO2002096805A3
WO2002096805A3 PCT/DE2002/001963 DE0201963W WO02096805A3 WO 2002096805 A3 WO2002096805 A3 WO 2002096805A3 DE 0201963 W DE0201963 W DE 0201963W WO 02096805 A3 WO02096805 A3 WO 02096805A3
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WO
WIPO (PCT)
Prior art keywords
components
analysis sample
mobility spectrometer
separation
supply
Prior art date
Application number
PCT/DE2002/001963
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English (en)
French (fr)
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WO2002096805A2 (de
Inventor
Michael Karas
Original Assignee
Michael Karas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Karas filed Critical Michael Karas
Priority to AU2002319075A priority Critical patent/AU2002319075A1/en
Priority to DE10292304.3T priority patent/DE10292304B4/de
Priority to US10/479,137 priority patent/US7015462B2/en
Publication of WO2002096805A2 publication Critical patent/WO2002096805A2/de
Publication of WO2002096805A3 publication Critical patent/WO2002096805A3/de

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Die zu separierenden Komponenten führen in der Driftröhre (5) des Ionenmobilitätsspektrometers in derart selektiver Weise Wechselwirkungsprozesse mit den einem Gaseingang (8) zugeführten und gezielt ausgewählten Partikeln, insbesondere enantiomeren Kollisionsmolekülen aus, daß sie bei ihrer Drift von dem Analysenprobeneingang (1) durch die Driftröhre (5) zu einem Ionenkollektor (7) unterschiedliche Beweglichkeiten aufweisen, wodurch die Ionen an dem Ionenkollektor (7) zeitversetzt detektierbar sind.
PCT/DE2002/001963 2001-05-28 2002-05-28 Separation von komponenten einer analysenprobe in einem ionenmobilitätsspektrometer durch zuführung selektiv wechselwirkender gasförmiger partikel WO2002096805A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002319075A AU2002319075A1 (en) 2001-05-28 2002-05-28 Separation of components of an analysis sample in an ion mobility spectrometer using a supply of selectively interactive gaseous particles
DE10292304.3T DE10292304B4 (de) 2001-05-28 2002-05-28 Separation von Komponenten einer Analysenprobe in einem Ionenmobilitätsspektrometer durch Zuführung selektiv wechselwirkender gasförmiger Partikel
US10/479,137 US7015462B2 (en) 2001-05-28 2002-05-28 Separation of components of an analysis sample in an ion mobility spectrometer using a supply of selectively interactive gaseous particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10125907A DE10125907A1 (de) 2001-05-28 2001-05-28 Separation von chiralen Substanzen in einem Ionenmobilitätsspektrometer durch Zuführung selektiv wechselwirkender Kollisionsgase
DE10125907.7 2001-05-28

Publications (2)

Publication Number Publication Date
WO2002096805A2 WO2002096805A2 (de) 2002-12-05
WO2002096805A3 true WO2002096805A3 (de) 2003-10-09

Family

ID=7686371

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2002/001963 WO2002096805A2 (de) 2001-05-28 2002-05-28 Separation von komponenten einer analysenprobe in einem ionenmobilitätsspektrometer durch zuführung selektiv wechselwirkender gasförmiger partikel

Country Status (4)

Country Link
US (1) US7015462B2 (de)
AU (1) AU2002319075A1 (de)
DE (2) DE10125907A1 (de)
WO (1) WO2002096805A2 (de)

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Publication number Priority date Publication date Assignee Title
CN102253112B (zh) * 2011-06-27 2013-05-22 武汉矽感科技有限公司 利用相对离子迁移率谱识别物质的方法

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Publication number Priority date Publication date Assignee Title
US7375317B2 (en) * 2004-08-02 2008-05-20 The Texas A&M University System Ion drift-chemical ionization mass spectrometry
US8785848B2 (en) * 2007-07-11 2014-07-22 Excellims Corporation Parallel ion mass and ion mobility analysis
CA2650240C (en) * 2006-04-20 2016-01-19 Axel Mie Method for separation of molecules
EP2040824A2 (de) * 2006-07-11 2009-04-01 Excellims Corporation Verfahren und vorrichtung für trennung und sammlung von molekülen auf der basis von ionenmobilität
GB0613900D0 (en) * 2006-07-13 2006-08-23 Micromass Ltd Mass spectrometer
US8063361B2 (en) 2008-02-05 2011-11-22 Excellims Corporation Ion mobility based separation methods and apparatus
WO2010042881A1 (en) * 2008-10-10 2010-04-15 Excellims Corporation Method and apparatus for chemical and biological sample separation
GB201506302D0 (en) * 2015-04-14 2015-05-27 Micromass Ltd Ion mobility separation buffer gas composition
JP6879120B2 (ja) * 2017-08-23 2021-06-02 株式会社島津製作所 光学異性体の分析方法及びイオン移動度分析装置

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US4551624A (en) * 1983-09-23 1985-11-05 Allied Corporation Ion mobility spectrometer system with improved specificity
EP0219602A2 (de) * 1985-08-01 1987-04-29 Allied Corporation Ionisationsdetektor
WO2000008454A1 (en) * 1998-08-05 2000-02-17 National Research Council Canada Method for separation of isomers and different conformations of ions in gaseous phase
US6225623B1 (en) * 1996-02-02 2001-05-01 Graseby Dynamics Limited Corona discharge ion source for analytical instruments

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SE452762B (sv) * 1985-06-28 1987-12-14 Borje Sellergren Anvendning av ett vattenhaltigt tvafassystem for kiral upplosning av racemiska blandningar eller for separation av diastereomerer samt ett sadant forfarande
US5234838A (en) 1990-04-17 1993-08-10 Environmental Technologies Group, Inc. Ammonia monitor based on ion mobility spectrometry with selective dopant chemistry
US5095206A (en) * 1990-06-01 1992-03-10 Environmental Technologies Group, Inc. Method and apparatus for improving the specificity of an ion mobility spectrometer utillizing sulfur dioxide dopant chemistry
US5306561A (en) 1992-02-20 1994-04-26 Cornell Research Foundation, Inc. Preparation of surface-functional polymer particles
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JPH09191892A (ja) * 1996-01-16 1997-07-29 Nippon Soda Co Ltd 含硫黄光学活性アルコールの製造法
DE19726152A1 (de) * 1997-06-20 1998-12-24 Merck Patent Gmbh Verwendung von monolithischen Sorbentien für die Enantiomerentrennung
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WO2000064572A2 (en) * 1999-04-26 2000-11-02 Rensselaer Polytechnic Institute Epoxy-functional polymeric microbeads
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Publication number Priority date Publication date Assignee Title
US4551624A (en) * 1983-09-23 1985-11-05 Allied Corporation Ion mobility spectrometer system with improved specificity
EP0219602A2 (de) * 1985-08-01 1987-04-29 Allied Corporation Ionisationsdetektor
US6225623B1 (en) * 1996-02-02 2001-05-01 Graseby Dynamics Limited Corona discharge ion source for analytical instruments
WO2000008454A1 (en) * 1998-08-05 2000-02-17 National Research Council Canada Method for separation of isomers and different conformations of ions in gaseous phase

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JACOBY M: "Fast separations for chiral drugs", SCIENCE & TECHNOLOGY, vol. 79, no. 21, 21 May 2001 (2001-05-21), pages 68 - 69, XP002246303 *
REID ASBURY G ET AL: "USING DIFFERENT DRIFT GASES TO CHANGE SEPARATION FACTORS (ALPHA) IN ION MOBILITY SPECTROMETRY", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 72, no. 3, 1 February 2000 (2000-02-01), pages 580 - 584, XP001147604, ISSN: 0003-2700 *
SCARCELLA D ET AL: "Optimization of a simple method for the chiral separation of phenethylamines of forensic interest based on cyclodextrin complexation capillary electrophoresis and its preliminary application to the analysis of human urine and hair", FORENSIC SCIENCE INTERNATIONAL, vol. 89, - 1997, XP002246304 *
WU C ET AL: "ELECTROSPRAY IONIZATION HIGH-RESOLUTION ION MOBILITY SPECTROMETRY-MASS SPECTROMETRY", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 70, 1 December 1998 (1998-12-01), pages 4929 - 4938, XP001147605, ISSN: 0003-2700 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102253112B (zh) * 2011-06-27 2013-05-22 武汉矽感科技有限公司 利用相对离子迁移率谱识别物质的方法

Also Published As

Publication number Publication date
DE10292304D2 (de) 2004-05-06
DE10125907A1 (de) 2002-12-12
AU2002319075A1 (en) 2002-12-09
WO2002096805A2 (de) 2002-12-05
US7015462B2 (en) 2006-03-21
DE10292304B4 (de) 2015-09-10
US20040178340A1 (en) 2004-09-16

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