WO2002092842A3 - Acides nucleiques et proteines correspondantes dits 101p3a11 ou phor-1 servant au traitement et a la detection de cancers - Google Patents

Acides nucleiques et proteines correspondantes dits 101p3a11 ou phor-1 servant au traitement et a la detection de cancers Download PDF

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Publication number
WO2002092842A3
WO2002092842A3 PCT/US2002/015520 US0215520W WO02092842A3 WO 2002092842 A3 WO2002092842 A3 WO 2002092842A3 US 0215520 W US0215520 W US 0215520W WO 02092842 A3 WO02092842 A3 WO 02092842A3
Authority
WO
WIPO (PCT)
Prior art keywords
phor
cancer
corresponsing
useful
detection
Prior art date
Application number
PCT/US2002/015520
Other languages
English (en)
Other versions
WO2002092842A2 (fr
Inventor
Aya Jakobovits
Mary Faris
Arthur B Raitano
Robert Kendall Morrison
Douglas Saffran
Wangmao Ge
Pia M Challita-Eid
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/001,469 external-priority patent/US7208280B2/en
Priority claimed from US10/017,066 external-priority patent/US6838258B2/en
Application filed by Agensys Inc filed Critical Agensys Inc
Priority to IL15886002A priority Critical patent/IL158860A0/xx
Priority to JP2002589708A priority patent/JP2005512509A/ja
Priority to EP02736898A priority patent/EP1539805A4/fr
Priority to AU2002309873A priority patent/AU2002309873B2/en
Priority to CA002447564A priority patent/CA2447564A1/fr
Publication of WO2002092842A2 publication Critical patent/WO2002092842A2/fr
Priority to IL158860A priority patent/IL158860A/en
Publication of WO2002092842A3 publication Critical patent/WO2002092842A3/fr
Priority to AU2008200363A priority patent/AU2008200363B2/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention porte sur un nouveau gène (dit 101P3A11 ou PHOR-1), sur la protéine correspondante et sur leurs variantes, le 101P3A11 présentant une expression spécifique dans les tissus adultes normaux, et une expression aberrante dans les cancers répertoriés dans la table (I). En conséquence le 101P3A11 constitue une cible pouvant servir pour les diagnostics, les pronostiques, la prophylaxie et la thérapie du cancer. Le gène 101P3A11 ou ses fragments ou la protéine correspondante, ou leurs variantes peuvent servir à provoquer une réponse immunitaire humorale ou cellulaire. Les anticorps ou cellules T réagissant avec le 101P3A11 peuvent servir à des immunisation actives ou passives.
PCT/US2002/015520 2001-05-15 2002-05-15 Acides nucleiques et proteines correspondantes dits 101p3a11 ou phor-1 servant au traitement et a la detection de cancers WO2002092842A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IL15886002A IL158860A0 (en) 2001-05-15 2002-05-15 Nucleic acids and corresponding proteins entitled 101p3a11 or phor-1 useful in treatment and detection of cancer and pharmaceutical compositions containing the same
JP2002589708A JP2005512509A (ja) 2001-05-15 2002-05-15 癌の処置および検出において有用な１０１ｐ３ａ１１またはｐｈｏｒ−１と名称が与えられる核酸および対応するタンパク質
EP02736898A EP1539805A4 (fr) 2001-05-15 2002-05-15 Acides nucleiques et proteines correspondantes dits 101p3a11 ou phor-1 servant au traitement et a la detection de cancers
AU2002309873A AU2002309873B2 (en) 2001-05-15 2002-05-15 Nucleic acids and corresponding proteins entitled 101P3A11 or PHOR-1 useful in treatment and detection of cancer
CA002447564A CA2447564A1 (fr) 2001-05-15 2002-05-15 Acides nucleiques et proteines correspondantes dits 101p3a11 ou phor-1 servant au traitement et a la detection de cancers
IL158860A IL158860A (en) 2001-05-15 2003-11-13 101p3a11 peptides for use in vaccine preparation
AU2008200363A AU2008200363B2 (en) 2001-05-15 2008-01-18 Nucleic acids and corresponding proteins entitled 101P3A11 or PHOR-1 useful in treatment and detection of cancer

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US29111801P 2001-05-15 2001-05-15
US60/291,118 2001-05-15
US10/001,469 2001-10-31
US10/001,469 US7208280B2 (en) 1999-10-05 2001-10-31 Nucleic acid and corresponding protein entitled 101P3A41 useful in treatment and detection of cancer
US10/017,666 2001-12-14
US10/017,066 US6838258B2 (en) 1999-10-05 2001-12-14 G protein-coupled receptor up-regulated in prostate cancer and uses thereof

Publications (2)

Publication Number Publication Date
WO2002092842A2 WO2002092842A2 (fr) 2002-11-21
WO2002092842A3 true WO2002092842A3 (fr) 2005-04-21

Family

ID=38616826

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/015520 WO2002092842A2 (fr) 2001-05-15 2002-05-15 Acides nucleiques et proteines correspondantes dits 101p3a11 ou phor-1 servant au traitement et a la detection de cancers

Country Status (6)

Country Link
EP (1) EP1539805A4 (fr)
JP (1) JP2005512509A (fr)
AU (2) AU2002309873B2 (fr)
CA (1) CA2447564A1 (fr)
IL (1) IL158860A0 (fr)
WO (1) WO2002092842A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361338B2 (en) 1999-10-05 2008-04-22 Agensys, Inc. Methods to inhibit growth of prostate cancer cells
US7208280B2 (en) 1999-10-05 2007-04-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 101P3A41 useful in treatment and detection of cancer
US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
SI1897548T1 (sl) 2003-02-28 2013-12-31 The Johns Hopkins University Regulacija celic T
JP5122592B2 (ja) * 2010-01-04 2013-01-16 アジェンシス，インコーポレイテッド 癌の処置および検出において有用な２４ｐ４ｃ１２と称される、核酸および対応タンパク質
US10722563B2 (en) * 2012-09-20 2020-07-28 Shenzhen Innovation Immunotechnology Co., Ltd. Prostate-specific tumor antigens and uses thereof
CN111549140B (zh) * 2020-06-08 2023-08-08 重庆医科大学附属第一医院 一种检测肺癌相关基因C2orf40、FIBIN和GRP甲基化的试剂盒及其应用

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000020590A2 (fr) * 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. Proteines de recepteurs couples a des proteines g
WO2001027158A2 (fr) * 1999-10-08 2001-04-19 Digiscents Sequences de recepteurs olfactifs
US20020022248A1 (en) * 1997-02-25 2002-02-21 Jiangchun Xu Compositions and methods for the therapy and diagnosis of prostate cancer
US20030022237A1 (en) * 2000-09-27 2003-01-30 Feder John N. Novel human G-protein coupled receptor, HGPRBMY4, expressed highly in prostate, colon, and lung
US20030088059A1 (en) * 2000-03-13 2003-05-08 Sergey Zozulya Human olfactory receptors and genes encoding same
US20030113798A1 (en) * 2000-12-19 2003-06-19 Burmer Glenna C. Antigenic peptides, such as for G protein-coupled receptors (GPCRS), antibodies thereto, and systems for identifying such antigenic peptides
US20030213004A1 (en) * 1999-10-05 2003-11-13 Aya Jakobovits Nucleic acids and corresponding proteins entitled 101P3A11 or PHOR-1 useful in treatment and detection of cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1225590A (zh) * 1996-03-11 1999-08-11 埃皮曼尼公司 对hla分子结合亲和力提高的肽
AU3215800A (en) * 1999-01-27 2000-08-18 Epimmune, Inc. Identification of broadly reactive hla restricted t cell epitopes
ES2371212T3 (es) * 1999-10-05 2011-12-28 Agensys, Inc. Receptor acoplado a proteína g regulado positivamente en el cáncer de próstata y usos del mismo.
EP1311673A2 (fr) * 2000-03-27 2003-05-21 Corixa Corporation Compositions et methodes de therapie et de diagnostic du cancer de la prostate
EP1274844A2 (fr) * 2000-03-31 2003-01-15 Curagen Corporation Nouvelles proteines et acides nucleiques codant pour celles-ci
US20030108963A1 (en) * 2001-07-25 2003-06-12 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020022248A1 (en) * 1997-02-25 2002-02-21 Jiangchun Xu Compositions and methods for the therapy and diagnosis of prostate cancer
WO2000020590A2 (fr) * 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. Proteines de recepteurs couples a des proteines g
US20030213004A1 (en) * 1999-10-05 2003-11-13 Aya Jakobovits Nucleic acids and corresponding proteins entitled 101P3A11 or PHOR-1 useful in treatment and detection of cancer
WO2001027158A2 (fr) * 1999-10-08 2001-04-19 Digiscents Sequences de recepteurs olfactifs
US20030088059A1 (en) * 2000-03-13 2003-05-08 Sergey Zozulya Human olfactory receptors and genes encoding same
US20030022237A1 (en) * 2000-09-27 2003-01-30 Feder John N. Novel human G-protein coupled receptor, HGPRBMY4, expressed highly in prostate, colon, and lung
US20030113798A1 (en) * 2000-12-19 2003-06-19 Burmer Glenna C. Antigenic peptides, such as for G protein-coupled receptors (GPCRS), antibodies thereto, and systems for identifying such antigenic peptides

Also Published As

Publication number Publication date
EP1539805A4 (fr) 2005-11-16
IL158860A0 (en) 2004-05-12
WO2002092842A2 (fr) 2002-11-21
JP2005512509A (ja) 2005-05-12
AU2002309873B2 (en) 2007-10-18
AU2008200363A8 (en) 2008-03-13
CA2447564A1 (fr) 2002-11-21
AU2008200363B2 (en) 2010-08-12
EP1539805A2 (fr) 2005-06-15
AU2008200363A1 (en) 2008-02-21

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