WO2004050828A3 - Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer - Google Patents

Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer Download PDF

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Publication number
WO2004050828A3
WO2004050828A3 PCT/US2002/038264 US0238264W WO2004050828A3 WO 2004050828 A3 WO2004050828 A3 WO 2004050828A3 US 0238264 W US0238264 W US 0238264W WO 2004050828 A3 WO2004050828 A3 WO 2004050828A3
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WO
WIPO (PCT)
Prior art keywords
cancer
useful
detection
treatment
nucleic acid
Prior art date
Application number
PCT/US2002/038264
Other languages
English (en)
Other versions
WO2004050828A2 (fr
Inventor
Arthur B Raitano
Karen Jane Meyrick Morrison
Wangmao Ge
Pia M Challita-Eid
Aya Jakobovits
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agensys Inc filed Critical Agensys Inc
Priority to AU2002352976A priority Critical patent/AU2002352976B2/en
Priority to PCT/US2002/038264 priority patent/WO2004050828A2/fr
Priority to CA2503346A priority patent/CA2503346C/fr
Priority to EP02789937A priority patent/EP1565200A4/fr
Priority to JP2004557078A priority patent/JP2006508163A/ja
Publication of WO2004050828A2 publication Critical patent/WO2004050828A2/fr
Publication of WO2004050828A3 publication Critical patent/WO2004050828A3/fr
Priority to IL167892A priority patent/IL167892A/en
Priority to AU2008200628A priority patent/AU2008200628B2/en
Priority to AU2009208065A priority patent/AU2009208065B2/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne un nouveau gène 024P4C12 (également nommé 24P4C12), sa protéine codée, ainsi que ses variants. Le gène 24P4C12 présente une expression tissulaire spécifique pour un tissu adulte normal, et est exprimé de manière aberrante dans les cancers énumérés dans la Table I. Le 24P4C12 constitue une cible diagnostique, pronostique, prophylactique et/ou thérapeutique contre le cancer. Le gène 24P4C12 ou un fragment de celui-ci, ou sa protéine codée, ou des variants ou un fragment de celle-ci, peuvent être utilisés pour déclencher une réponse immunitaire humorale ou cellulaire, et des anticorps ou des lymphocytes T réagissant avec le 24P4C12 peuvent être utilisés dans l'immunisation active ou passive.
PCT/US2002/038264 2002-11-27 2002-11-27 Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer WO2004050828A2 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU2002352976A AU2002352976B2 (en) 2002-11-27 2002-11-27 Nucleic acid corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
PCT/US2002/038264 WO2004050828A2 (fr) 2002-11-27 2002-11-27 Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer
CA2503346A CA2503346C (fr) 2002-11-27 2002-11-27 Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer
EP02789937A EP1565200A4 (fr) 2002-11-27 2002-11-27 Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer
JP2004557078A JP2006508163A (ja) 2002-11-27 2002-11-27 癌の処置および検出において有用な２４ｐ４ｃ１２と称される、核酸および対応タンパク質
IL167892A IL167892A (en) 2002-11-27 2005-04-06 Nucleic acid and protein entitled 24p4c12 and compositions containing the same and uses thereof
AU2008200628A AU2008200628B2 (en) 2002-11-27 2008-02-08 Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
AU2009208065A AU2009208065B2 (en) 2002-11-27 2009-08-07 Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/038264 WO2004050828A2 (fr) 2002-11-27 2002-11-27 Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer

Publications (2)

Publication Number Publication Date
WO2004050828A2 WO2004050828A2 (fr) 2004-06-17
WO2004050828A3 true WO2004050828A3 (fr) 2004-12-09

Family

ID=32467113

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/038264 WO2004050828A2 (fr) 2002-11-27 2002-11-27 Acide nucleique 24p4c12 et proteine correspondante utilises dans le traitement et la detection du cancer

Country Status (6)

Country Link
EP (1) EP1565200A4 (fr)
JP (1) JP2006508163A (fr)
AU (3) AU2002352976B2 (fr)
CA (1) CA2503346C (fr)
IL (1) IL167892A (fr)
WO (1) WO2004050828A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009033094A2 (fr) * 2007-09-07 2009-03-12 Agensys, Inc. Anticorps et molécules apparentées qui se lient aux protéines 24p4c12
EP2403524A4 (fr) * 2009-03-06 2012-09-26 Agensys Inc Conjugues anticorps-medicament (adc) se liant aux proteines 24p4c12
JP2013049646A (ja) * 2011-08-30 2013-03-14 Tokyo Medical Univ 癌治療剤
BR112018006263A2 (pt) 2015-10-02 2018-10-16 Memorial Sloan Kettering Cancer Center inibidor de tonsl, molécula pequena, uso de uma molécula pequena ou de um inibidor, cristal tridimensional, métodos para selecionar ou desenhar uma molécula pequena, para identificar um inibidor de ligação de ard de tonsl à histona h4, para predizer o efeito de inibição de tonsl e para identificar um inibidor de tonsl e/ou determinar o efeito inibitório de um inibidor putativo de tonsl, sequência de polinucleotídeo ou sequência de aminoácidos isolada, e, polipeptídeo mutante de tonsl.
JP7438662B2 (ja) 2016-01-25 2024-02-27 ジェネンテック， インコーポレイテッド Ｔ細胞依存性二重特異的抗体をアッセイするための方法
EP3617312A4 (fr) * 2017-04-28 2021-04-07 Hoyu Co., Ltd. Antigène d'allergie et épitope associé

Citations (1)

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Publication number Priority date Publication date Assignee Title
US20030147904A1 (en) * 1999-04-12 2003-08-07 Afar Daniel E. Novel 13-transmembrane protein expressed in prostate cancer

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Also Published As

Publication number Publication date
AU2008200628B2 (en) 2009-05-07
AU2008200628A1 (en) 2008-03-06
AU2002352976A1 (en) 2004-06-23
CA2503346A1 (fr) 2004-06-17
CA2503346C (fr) 2014-03-18
IL167892A (en) 2012-06-28
AU2009208065A1 (en) 2009-08-27
EP1565200A4 (fr) 2009-06-24
AU2002352976B2 (en) 2007-11-08
AU2009208065B2 (en) 2012-05-24
WO2004050828A2 (fr) 2004-06-17
EP1565200A2 (fr) 2005-08-24
JP2006508163A (ja) 2006-03-09

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