WO2002090512A3 - Haplotypes du gene nnmt - Google Patents

Haplotypes du gene nnmt Download PDF

Info

Publication number
WO2002090512A3
WO2002090512A3 PCT/US2002/014538 US0214538W WO02090512A3 WO 2002090512 A3 WO2002090512 A3 WO 2002090512A3 US 0214538 W US0214538 W US 0214538W WO 02090512 A3 WO02090512 A3 WO 02090512A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
nnmt
gene
disclosed
nnmt gene
Prior art date
Application number
PCT/US2002/014538
Other languages
English (en)
Other versions
WO2002090512A2 (fr
Inventor
Anne Chew
Christopher Raleigh Gilson
Amir Kazemi
Beena Koshy
Original Assignee
Genaissance Pharmaceuticals
Anne Chew
Christopher Raleigh Gilson
Amir Kazemi
Beena Koshy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Anne Chew, Christopher Raleigh Gilson, Amir Kazemi, Beena Koshy filed Critical Genaissance Pharmaceuticals
Priority to AU2002257254A priority Critical patent/AU2002257254A1/en
Publication of WO2002090512A2 publication Critical patent/WO2002090512A2/fr
Publication of WO2002090512A3 publication Critical patent/WO2002090512A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention concerne des variantes génétiques du gène de la Nicotinamide N-Méthyltransférase (NNMT). L'invention concerne plus particulièrement divers génotypes, haplotypes, et paires de haplotypes présents généralement dans la population des Etats Unis d'Amérique pour le gène NNMT. L'invention concerne également des compositions et procédés de haplotypage et/ou de génotypage du gène NNMT chez un individu. L'invention concerne enfin des polynucléotides définis par les haplotypes de l'invention.
PCT/US2002/014538 2001-05-07 2002-05-07 Haplotypes du gene nnmt WO2002090512A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002257254A AU2002257254A1 (en) 2001-05-07 2002-05-07 Haplotypes of the nnmt gene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28933501P 2001-05-07 2001-05-07

Publications (2)

Publication Number Publication Date
WO2002090512A2 WO2002090512A2 (fr) 2002-11-14
WO2002090512A3 true WO2002090512A3 (fr) 2007-11-22

Family

ID=23111084

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/014538 WO2002090512A2 (fr) 2001-05-07 2002-05-07 Haplotypes du gene nnmt

Country Status (2)

Country Link
AU (1) AU2002257254A1 (fr)
WO (1) WO2002090512A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100437115C (zh) * 2002-12-20 2008-11-26 霍夫曼-拉罗奇有限公司 烟酰胺n-甲基转移酶作为结肠直肠癌标志的用途
EP1541695A1 (fr) * 2003-12-09 2005-06-15 Nanogen Recognomics GmbH Méthode à déterminer le caractère maligne de melanoma utilisant une mutation dans le BRAF gène
AU2005287855B2 (en) * 2004-09-24 2011-06-16 Mesoblast, Inc. Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AKSOY ET AL.: "Human nicotinamide N-methyltransferase gene: molecular cloning, structural characterization and chromosomal localization", GENOMICS, vol. 29, 1995, pages 555 - 561, XP002959533 *
DATABASE GENBANK [online] 9 September 2000 (2000-09-09), BIRREN ET AL.: "Homo sapiens clone RP11-649M10, working draft sequence, 15 unordered pieces", XP002959532, Database accession no. (AC019290) *
SAITO ET AL.: "Identification of 197 genetic variations in six human methyltransferase genes in the Japanese population", J. HUM. GENET., vol. 46, 2001, pages 529 - 537, XP002959535 *
YAN ET AL.: "Human nicotinamide N-methyltransferase pharmacogenetics: gene sequence analysis and promoter characterization", PHARMACOGENETICS, vol. 9, 1999, pages 307 - 316, XP002959534 *

Also Published As

Publication number Publication date
AU2002257254A1 (en) 2002-11-18
WO2002090512A2 (fr) 2002-11-14
AU2002257254A8 (en) 2008-01-17

Similar Documents

Publication Publication Date Title
WO2002026768A3 (fr) Haplotypes du gene por
WO2002090512A3 (fr) Haplotypes du gene nnmt
WO2002008425A3 (fr) Haplotypes du gene adrb3
WO2002018414A3 (fr) Haplotypes du gène bf
WO2001079228A3 (fr) Haplotypes du gene f12
WO2002012562A3 (fr) Haplotypes du gene pla2g1b
WO2002032928A3 (fr) Haplotypes du gene hrh1
WO2001087909A3 (fr) Haplotypes du gene aanat
WO2002090378A3 (fr) Haplotypes du gene de ces2
WO2001090127A3 (fr) Haplotypes du gene de hoxd3
WO2002042320A3 (fr) Haplotypes du gene de glutathione reductase
WO2002040502A3 (fr) Haplotypes du gene de la lipase hormono-sensible
WO2002012499A3 (fr) Haplotypes du gene ntf3
WO2002030950A3 (fr) Haplotypes du gene fy
WO2002044201A3 (fr) Haplotypes du gene sah
WO2001090118A3 (fr) Haplotypes du gene edn2
WO2002038586A3 (fr) Haplotypes du gene il6
WO2002010190A3 (fr) Haplotypes du gene il12b
WO2001098315A3 (fr) Haplotypes du gene hmgcl
WO2002036610A3 (fr) Haplotypes du gene adora3
WO2002055534A3 (fr) Haplotypes du gene f2rli
WO2001087907A3 (fr) Haplotypes du gene de l'osm
WO2001092278A3 (fr) Haplotypes du gene rlbp1
WO2001085742A3 (fr) Haplotypes du gene npy1r
WO2002002580A3 (fr) Haplotypes du gene etfb

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP