WO2001090118A3 - Haplotypes du gene edn2 - Google Patents

Haplotypes du gene edn2 Download PDF

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Publication number
WO2001090118A3
WO2001090118A3 PCT/US2001/016433 US0116433W WO0190118A3 WO 2001090118 A3 WO2001090118 A3 WO 2001090118A3 US 0116433 W US0116433 W US 0116433W WO 0190118 A3 WO0190118 A3 WO 0190118A3
Authority
WO
WIPO (PCT)
Prior art keywords
haplotypes
edn2
gene
disclosed
edn2 gene
Prior art date
Application number
PCT/US2001/016433
Other languages
English (en)
Other versions
WO2001090118A2 (fr
Inventor
Amir Kazemi
Beena Koshy
Debra A Tanguay
Original Assignee
Genaissance Pharmaceuticals
Amir Kazemi
Beena Koshy
Debra A Tanguay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genaissance Pharmaceuticals, Amir Kazemi, Beena Koshy, Debra A Tanguay filed Critical Genaissance Pharmaceuticals
Priority to AU2001261802A priority Critical patent/AU2001261802A1/en
Publication of WO2001090118A2 publication Critical patent/WO2001090118A2/fr
Publication of WO2001090118A3 publication Critical patent/WO2001090118A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des variants génétiques du gène de l'endothéline 2 (EDN2) ainsi que différents génotypes, haplotypes et paires d'haplotypes existant dans la population générale des Etats-Unis d'Amérique pour ce gène EDN2. L'invention concerne également des compositions et des procédés pour l'haplotypage et/ou le génotypage du gène EDN2 chez un individu. L'invention concerne enfin des polynucléotides définis par la séquence des haplotypes décrits.
PCT/US2001/016433 2000-05-19 2001-05-21 Haplotypes du gene edn2 WO2001090118A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001261802A AU2001261802A1 (en) 2000-05-19 2001-05-21 Haplotypes of the edn2 gene

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20576100P 2000-05-19 2000-05-19
US60/205,761 2000-05-19

Publications (2)

Publication Number Publication Date
WO2001090118A2 WO2001090118A2 (fr) 2001-11-29
WO2001090118A3 true WO2001090118A3 (fr) 2003-10-30

Family

ID=22763539

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016433 WO2001090118A2 (fr) 2000-05-19 2001-05-21 Haplotypes du gene edn2

Country Status (2)

Country Link
AU (1) AU2001261802A1 (fr)
WO (1) WO2001090118A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102827867A (zh) * 2011-06-16 2012-12-19 天津药物研究院 一种et2稳定表达细胞系的建立及其在药物筛选中的应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] ONDA ET AL.: "Human endothelin-2 gene containing promoter", XP002905974, Database accession no. E07666 *
SHARMA ET AL.: "Structure of human endothelin-2 gene and demonstration of common expression in human right atrial tissue", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 245, April 1998 (1998-04-01), pages 709 - 712, XP002905973 *

Also Published As

Publication number Publication date
AU2001261802A1 (en) 2001-12-03
WO2001090118A2 (fr) 2001-11-29

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