WO2002020756A3 - Molécules sécrétoires - Google Patents

Molécules sécrétoires Download PDF

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Publication number
WO2002020756A3
WO2002020756A3 PCT/US2001/027297 US0127297W WO0220756A3 WO 2002020756 A3 WO2002020756 A3 WO 2002020756A3 US 0127297 W US0127297 W US 0127297W WO 0220756 A3 WO0220756 A3 WO 0220756A3
Authority
WO
WIPO (PCT)
Prior art keywords
sptm
provides
diagnostic assays
purified
antibodies
Prior art date
Application number
PCT/US2001/027297
Other languages
English (en)
Other versions
WO2002020756A2 (fr
Inventor
Stuart E Jackson
Stephen E Lincoln
Christina M Altus
Gerard E Dufour
Michael S Chalup
Original Assignee
Incyte Genomics Inc
Stuart E Jackson
Stephen E Lincoln
Christina M Altus
Gerard E Dufour
Michael S Chalup
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Stuart E Jackson, Stephen E Lincoln, Christina M Altus, Gerard E Dufour, Michael S Chalup filed Critical Incyte Genomics Inc
Priority to EP01966516A priority Critical patent/EP1368375A2/fr
Priority to CA002419943A priority patent/CA2419943A1/fr
Priority to AU2001287022A priority patent/AU2001287022A1/en
Priority to AU8702201A priority patent/AU8702201A/xx
Publication of WO2002020756A2 publication Critical patent/WO2002020756A2/fr
Publication of WO2002020756A3 publication Critical patent/WO2002020756A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Cette invention a trait à des polynucléotides sécréteurs purifiés (sptm) et aux polypeptides (SPTM) codés par ceux-ci. Elle concerne également l'utilisation de sptm, ou de compléments, ou d'oligonucléotides, ou de fragments de ces derniers dans des épreuves diagnostiques. L'invention concerne en outre des vecteurs et des cellules hôtes contenant des sptm aux fins de l'expression de SPTM. L'invention concerne aussi l'utilisation de SPTM isolées et purifiées pour induire des anticorps et pour examiner des bibliothèques de composés et l'utilisation d'anticorps anti-SPTM dans des épreuves diagnostiques. L'invention concerne enfin des jeux ordonnés de microéchantillons contenant des sptm et des procédés d'utilisation.
PCT/US2001/027297 2000-09-05 2001-08-30 Molécules sécrétoires WO2002020756A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01966516A EP1368375A2 (fr) 2000-09-05 2001-08-30 Molecules secreteres
CA002419943A CA2419943A1 (fr) 2000-09-05 2001-08-30 Molecules secretoires
AU2001287022A AU2001287022A1 (en) 2000-09-05 2001-08-30 Secretory molecules
AU8702201A AU8702201A (en) 2000-09-05 2001-08-31 Secretory molecules

Applications Claiming Priority (56)

Application Number Priority Date Filing Date Title
US22974700P 2000-09-05 2000-09-05
US22975000P 2000-09-05 2000-09-05
US22974800P 2000-09-05 2000-09-05
US22974900P 2000-09-05 2000-09-05
US23058300P 2000-09-05 2000-09-05
US22975100P 2000-09-05 2000-09-05
US23001600P 2000-09-05 2000-09-05
US60/229,748 2000-09-05
US60/230,583 2000-09-05
US60/230,016 2000-09-05
US60/229,747 2000-09-05
US60/229,749 2000-09-05
US60/229,750 2000-09-05
US60/229,751 2000-09-05
US23059900P 2000-09-06 2000-09-06
US23098800P 2000-09-06 2000-09-06
US23099000P 2000-09-06 2000-09-06
US23059500P 2000-09-06 2000-09-06
US23061000P 2000-09-06 2000-09-06
US23059600P 2000-09-06 2000-09-06
US23050500P 2000-09-06 2000-09-06
US23051700P 2000-09-06 2000-09-06
US23051800P 2000-09-06 2000-09-06
US23051500P 2000-09-06 2000-09-06
US23086400P 2000-09-06 2000-09-06
US23051400P 2000-09-06 2000-09-06
US23098900P 2000-09-06 2000-09-06
US23086500P 2000-09-06 2000-09-06
US23051900P 2000-09-06 2000-09-06
US23059700P 2000-09-06 2000-09-06
US60/230,505 2000-09-06
US60/230,515 2000-09-06
US60/230,610 2000-09-06
US60/230,864 2000-09-06
US60/230,519 2000-09-06
US60/230,990 2000-09-06
US60/230,517 2000-09-06
US60/230,595 2000-09-06
US60/230,518 2000-09-06
US60/230,514 2000-09-06
US60/230,596 2000-09-06
US60/230,988 2000-09-06
US60/230,597 2000-09-06
US60/230,989 2000-09-06
US60/230,599 2000-09-06
US60/230,865 2000-09-06
US23095100P 2000-09-07 2000-09-07
US23089600P 2000-09-07 2000-09-07
US23183200P 2000-09-07 2000-09-07
US23089700P 2000-09-07 2000-09-07
US23116300P 2000-09-07 2000-09-07
US60/230,951 2000-09-07
US60/230,896 2000-09-07
US60/231,832 2000-09-07
US60/231,163 2000-09-07
US60/230,897 2000-09-07

Publications (2)

Publication Number Publication Date
WO2002020756A2 WO2002020756A2 (fr) 2002-03-14
WO2002020756A3 true WO2002020756A3 (fr) 2003-08-28

Family

ID=27586833

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/027297 WO2002020756A2 (fr) 2000-09-05 2001-08-30 Molécules sécrétoires

Country Status (4)

Country Link
EP (1) EP1368375A2 (fr)
AU (1) AU2001287022A1 (fr)
CA (1) CA2419943A1 (fr)
WO (1) WO2002020756A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016593A2 (fr) 2000-08-22 2002-02-28 Agensys, Inc. Acide nucleique et proteine correspondante nomme 158p1d7 servant dans le traitement et la detection du cancer de la vesicule et d'autres cancers
US7358353B2 (en) 2000-08-22 2008-04-15 Agensys, Inc. Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers
GB0027905D0 (en) * 2000-11-15 2000-12-27 Glaxo Group Ltd New protein
WO2003072723A2 (fr) * 2002-02-22 2003-09-04 Incyte Corporation Molecules de signalisation intracellulaire
AU2003237367A1 (en) 2002-06-03 2003-12-19 Chiron Corporation Use of nrg4, or inhibitors thereof, in the treatment of colon and pancreatic cancer
JP2004267015A (ja) * 2003-03-05 2004-09-30 National Institute Of Advanced Industrial & Technology 核酸及び該核酸を用いた癌化検定方法
SG11201501286PA (en) 2012-08-23 2015-05-28 Agensys Inc Antibody drug conjugates (adc) that bind to 158p1d7 proteins
CN110850088B (zh) * 2019-12-06 2021-08-20 四川大学华西医院 Gtf2ird2自身抗体检测试剂在制备肺癌筛查试剂盒中的用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045712A2 (fr) * 1997-04-08 1998-10-15 Human Genome Sciences, Inc. 20 proteines humaines secretees
WO2001062918A2 (fr) * 2000-02-24 2001-08-30 Incyte Genomics, Inc. Molecules secretoires

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045712A2 (fr) * 1997-04-08 1998-10-15 Human Genome Sciences, Inc. 20 proteines humaines secretees
WO2001062918A2 (fr) * 2000-02-24 2001-08-30 Incyte Genomics, Inc. Molecules secretoires

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 6 October 1999 (1999-10-06), BIRREN ET AL.: "Homo sapiens chromosome , clone RP11-13J17, complete sequence.", XP002216605, retrieved from EBI Database accession no. AC011276 *
HAMADA T ET AL: "Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 176, no. 1-2, 17 October 1996 (1996-10-17), pages 211 - 214, XP004070231, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
CA2419943A1 (fr) 2002-03-14
WO2002020756A2 (fr) 2002-03-14
AU2001287022A1 (en) 2002-03-22
EP1368375A2 (fr) 2003-12-10

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