WO2002097031A3 - Molecules utilisees a des fins diagnostiques et therapeutiques - Google Patents

Molecules utilisees a des fins diagnostiques et therapeutiques Download PDF

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Publication number
WO2002097031A3
WO2002097031A3 PCT/US2002/010056 US0210056W WO02097031A3 WO 2002097031 A3 WO2002097031 A3 WO 2002097031A3 US 0210056 W US0210056 W US 0210056W WO 02097031 A3 WO02097031 A3 WO 02097031A3
Authority
WO
WIPO (PCT)
Prior art keywords
dithp
provides
therapeutics
diagnostics
diagnostic assays
Prior art date
Application number
PCT/US2002/010056
Other languages
English (en)
Other versions
WO2002097031A2 (fr
Inventor
Abel Daffo
Anissa Lee Jones
Alanna-Phung B Tran
Christopher R Dahl
Darryl Gietzen
Original Assignee
Incyte Genomics Inc
Abel Daffo
Anissa Lee Jones
Alanna-Phung B Tran
Christopher R Dahl
Darryl Gietzen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Abel Daffo, Anissa Lee Jones, Alanna-Phung B Tran, Christopher R Dahl, Darryl Gietzen filed Critical Incyte Genomics Inc
Priority to AU2002344208A priority Critical patent/AU2002344208A1/en
Priority to CA002442705A priority patent/CA2442705A1/fr
Publication of WO2002097031A2 publication Critical patent/WO2002097031A2/fr
Publication of WO2002097031A3 publication Critical patent/WO2002097031A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polynucléotides humains purifiés utilisés à des fins diagnostiques et thérapeutiques (dithp). L'invention concerne par ailleurs des polypeptides (DITHP) codés par dithp, l'utilisation de dithp, ou de compléments, d'oligonucléotides, ou de fragments de celle-ci dans des méthodes diagnostiques. De plus, l'invention concerne des vecteurs et des cellules hôtes contenant dithp pour l'expression de DITHP. L'invention concerne en outre l'utilisation de DITHP isolée et purifiée pour induire des anticorps et cribler des banques de composés ainsi que l'utilisation des anticorps anti-DITHP dans des méthodes d'agnostiques. L'invention concerne enfin des micro-réseaux contenant dithp et des méthodes d'utilisation correspondantes.
PCT/US2002/010056 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques WO2002097031A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002344208A AU2002344208A1 (en) 2001-03-28 2002-03-27 Molecules for diagnostics and therapeutics
CA002442705A CA2442705A1 (fr) 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US27961901P 2001-03-28 2001-03-28
US60/279,619 2001-03-28
US28006801P 2001-03-29 2001-03-29
US28006701P 2001-03-29 2001-03-29
US60/280,067 2001-03-29
US60,280,068 2001-03-29
US29128001P 2001-05-16 2001-05-16
US60/291,280 2001-05-16
US29182901P 2001-05-17 2001-05-17
US29184901P 2001-05-17 2001-05-17
US60,291,829 2001-05-17
US60/291,849 2001-05-17
US29942801P 2001-06-19 2001-06-19
US60,299,428 2001-06-19
US30000101P 2001-06-20 2001-06-20
US29977601P 2001-06-20 2001-06-20
US60/300,001 2001-06-20
US60/299,776 2001-06-20

Publications (2)

Publication Number Publication Date
WO2002097031A2 WO2002097031A2 (fr) 2002-12-05
WO2002097031A3 true WO2002097031A3 (fr) 2005-05-12

Family

ID=27578771

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2002/010056 WO2002097031A2 (fr) 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques
PCT/US2002/009944 WO2002079449A2 (fr) 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2002/009944 WO2002079449A2 (fr) 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies

Country Status (4)

Country Link
EP (1) EP1383894A2 (fr)
AU (2) AU2002338265A1 (fr)
CA (2) CA2442705A1 (fr)
WO (2) WO2002097031A2 (fr)

Cited By (2)

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US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug
CN111621525B (zh) * 2020-06-18 2021-04-23 中赛干细胞基因工程有限公司 Stx1b基因在促进人脂肪间充质干细胞生长和分化中的用途

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US7244827B2 (en) 2000-04-12 2007-07-17 Agensys, Inc. Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
EP1434783A4 (fr) * 2001-03-16 2006-06-07 Lilly Co Eli Proteines de mammiferes lp et reactifs associes
ATE364690T1 (de) 2001-11-09 2007-07-15 Proteologics Inc Posh nukleinsäure, polypeptide und darauf bezogene verfahren
US8753822B2 (en) * 2001-12-04 2014-06-17 Wayne State University Neoepitope detection of disease using protein arrays
US8450067B2 (en) * 2002-05-28 2013-05-28 Omrix Biopharmaceuticals Inc. Method for obtaining anti-idiotype antibodies
US20040053304A1 (en) 2002-06-05 2004-03-18 Case Western Reserve University Methods and compositions for detecting cancers
WO2004016733A2 (fr) 2002-08-16 2004-02-26 Agensys, Inc. Acides nucleiques et proteines correspondantes connues sous 251p5g2 que l'on utilise dans le traitement et la detection de cancers
TW200413539A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Genes and polypeptides relating to prostate cancers
EP1507006A4 (fr) * 2002-10-11 2006-05-24 Yamanouchi Pharma Co Ltd Procede de criblage d'un medicament contre l'insuffisance renale
EP2311870A1 (fr) * 2002-11-26 2011-04-20 Genentech, Inc. Compositions et procédés pour le traitement de maladies liées au système immunitaire
US7396666B2 (en) * 2002-12-27 2008-07-08 National Institute Of Advanced Industrial Science And Technology Glycosyltransferase, nucleic acid encoding the glycosyltransferase and method of testing canceration using the nucleic acid
GB0315827D0 (en) * 2003-07-05 2003-08-13 Imp College Innovations Ltd Methods
US20080274975A1 (en) * 2004-04-12 2008-11-06 The Trustees Of Columbia University In The City Of New Yourk Methods and Compositions for Inhibiting Abad/Abeta Protein Interaction
EP1627922A1 (fr) * 2004-08-18 2006-02-22 Sanofi-Aventis Deutschland GmbH Méthode de sélection d'agonistes et d'antagonistes du transporteur de carnitine et son utilisation
GB0423126D0 (en) * 2004-10-18 2004-11-17 Ares Trading Sa Protein
US7727725B2 (en) * 2006-04-27 2010-06-01 Celera Corporation Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
WO2008070090A2 (fr) 2006-12-05 2008-06-12 Oncomed Pharmaceuticals, Inc. Compositions et procédés pour diagnostiquer et traiter un cancer
US20110250218A1 (en) 2008-10-29 2011-10-13 Fong Lawrence H Disease-Associated Antigens and Methods of Use Thereof
AU2009313808B2 (en) 2008-11-14 2013-05-16 Gen-Probe Incorporated Compositions, kits and methods for detection of campylobacter nucleic acid
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
CN107098958B (zh) 2010-03-26 2021-11-05 达特茅斯大学理事会 Vista调节性t细胞介体蛋白、vista结合剂及其用途
PE20140608A1 (es) 2010-09-22 2014-06-12 Alios Biopharma Inc Analogos de nucleotidos sustituidos
EP2794630A4 (fr) 2011-12-22 2015-04-01 Alios Biopharma Inc Analogues de nucléotide phosphorothioate substitués
WO2013142157A1 (fr) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Combinaisons pharmaceutiques comprenant un analogue thionucléotidique
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
CA2884704C (fr) 2012-09-07 2023-04-04 Randolph J. Noelle Modulateurs vista de diagnostic et de traitement de cancer
MX369173B (es) 2013-12-24 2019-10-30 Janssen Pharmaceutica Nv Anticuerpos y fragmentos anti-vista.
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
CN107073109B (zh) 2014-06-11 2021-08-06 凯西·A·格林 Vista激动剂和拮抗剂抑制或增强体液免疫的用途
WO2016090347A1 (fr) 2014-12-05 2016-06-09 Immunext, Inc. Identification de vsig8 en tant que récepteur putatif de vista et son utilisation pour produire des modulateurs de vista/vsig8
BR112017027870A2 (pt) 2015-06-24 2018-08-28 Janssen Pharmaceutica Nv anticorpos e fragmentos anti-vista
BR112018016461A2 (pt) 2016-02-12 2019-10-01 Janssen Pharmaceutica Nv anticorpos e fragmentos anti-vista, usos dos mesmos e métodos de identificação dos mesmos
MX2018012469A (es) 2016-04-15 2019-07-04 Immunext Inc Anticuerpos vista antihumanos y uso de los mismos.
WO2020006108A2 (fr) * 2018-06-26 2020-01-02 Duke University Récepteurs odorants synthétiques
CN110714017B (zh) * 2019-11-06 2023-09-01 河南师范大学 锦鲤ptps基因、编码蛋白及应用
CN114317732B (zh) * 2021-04-08 2023-08-18 博尔诚（北京）科技有限公司 用于肺癌筛查的组合物及其应用

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug
CN111621525B (zh) * 2020-06-18 2021-04-23 中赛干细胞基因工程有限公司 Stx1b基因在促进人脂肪间充质干细胞生长和分化中的用途

Also Published As

Publication number Publication date
AU2002338265A1 (en) 2002-10-15
CA2447183A1 (fr) 2002-10-10
CA2442705A1 (fr) 2002-12-05
WO2002097031A2 (fr) 2002-12-05
AU2002344208A1 (en) 2002-12-09
WO2002079449A3 (fr) 2003-03-20
AU2002344208A8 (en) 2005-11-17
WO2002079449A2 (fr) 2002-10-10
EP1383894A2 (fr) 2004-01-28

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