CA2447183A1 - Molecules permettant de detecter et de traiter des maladies - Google Patents

Molecules permettant de detecter et de traiter des maladies Download PDF

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Publication number
CA2447183A1
CA2447183A1 CA002447183A CA2447183A CA2447183A1 CA 2447183 A1 CA2447183 A1 CA 2447183A1 CA 002447183 A CA002447183 A CA 002447183A CA 2447183 A CA2447183 A CA 2447183A CA 2447183 A1 CA2447183 A1 CA 2447183A1
Authority
CA
Canada
Prior art keywords
polynucleotide
sequence
mddt
sequences
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002447183A
Other languages
English (en)
Inventor
Abel Daffo
Anissa L. Jones
Alanna-Phung B. Tran
Christopher R. Dahl
Darryl Gietzen
Joyce Chinn
Gerard E. Dufour
Jennifer L. Hillman
Jimmy Y. Yu
Olivia Tuason
Pierre E. Yap
Stefan R. Amshey
Sean C. Daugherty
Tam C. Dam
Tommy F. Liu
Duy-Viet An Nguyen
Yael Kleefeld
Edward H. Gerstin, Jr.
Careyna H. Peralta
Marie H. David
Samantha A. Lewis
Alice J. Chen
Scott R. Panzer
Bernard Harris
Vincent Flores
Rakesh Marwaha
Audrey Lo
Ruth Y. Lan
Michael E. Urashka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2447183A1 publication Critical patent/CA2447183A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne des polynucléotides (mddt) purifiées de molécules permettant de détecter et de traiter des maladies ainsi que les polypeptides (MDDT) codés par les mddt. L'invention se rapporte en outre à l'utilisation de mddt, ou de compléments, d'oligonucléotides, ou de fragments de ceux-ci dans des méthodes diagnostiques. L'invention concerne également des vecteurs et des cellules hôtes comportant des mddt pour l'expression des MDDT. Par ailleurs, l'invention a trait à l'utilisation de MDDT isolés et purifiés pour induire la production d'anticorps et cribler des bibliothèques de composés, ainsi qu'à l'utilisation d'anticorps dirigés contre des MDDT dans des méthodes diagnostiques. L'invention concerne en outre des microréseaux contenant des mddt ainsi que leurs méthodes d'utilisation.
CA002447183A 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies Abandoned CA2447183A1 (fr)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US27961901P 2001-03-28 2001-03-28
US60/279,619 2001-03-28
US28006801P 2001-03-29 2001-03-29
US28006701P 2001-03-29 2001-03-29
US60/280,068 2001-03-29
US60/280,067 2001-03-29
US29128001P 2001-05-16 2001-05-16
US60/291,280 2001-05-16
US29184901P 2001-05-17 2001-05-17
US29182901P 2001-05-17 2001-05-17
US60/291,849 2001-05-17
US60/291,829 2001-05-17
US29942801P 2001-06-19 2001-06-19
US60/299,428 2001-06-19
US30000101P 2001-06-20 2001-06-20
US29977601P 2001-06-20 2001-06-20
US60/300,001 2001-06-20
US60/299,776 2001-06-20
PCT/US2002/009944 WO2002079449A2 (fr) 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies

Publications (1)

Publication Number Publication Date
CA2447183A1 true CA2447183A1 (fr) 2002-10-10

Family

ID=27578771

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002442705A Abandoned CA2442705A1 (fr) 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques
CA002447183A Abandoned CA2447183A1 (fr) 2001-03-28 2002-03-27 Molecules permettant de detecter et de traiter des maladies

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002442705A Abandoned CA2442705A1 (fr) 2001-03-28 2002-03-27 Molecules utilisees a des fins diagnostiques et therapeutiques

Country Status (4)

Country Link
EP (1) EP1383894A2 (fr)
AU (2) AU2002338265A1 (fr)
CA (2) CA2442705A1 (fr)
WO (2) WO2002097031A2 (fr)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244827B2 (en) 2000-04-12 2007-07-17 Agensys, Inc. Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
AU2002250143A1 (en) * 2001-03-16 2002-10-03 Eli Lilly And Company Lp mammalian proteins; related reagents
ATE364690T1 (de) 2001-11-09 2007-07-15 Proteologics Inc Posh nukleinsäure, polypeptide und darauf bezogene verfahren
US8753822B2 (en) * 2001-12-04 2014-06-17 Wayne State University Neoepitope detection of disease using protein arrays
IL165364A0 (en) * 2002-05-28 2006-01-15 Omrix Biopharmaceuticals Inc Method for obtaining anti-idiotype antibodies
EP1551437A4 (fr) 2002-06-05 2006-03-29 Univ Case Western Reserve Methodes et compositions pour detecter des cancers
WO2004016733A2 (fr) 2002-08-16 2004-02-26 Agensys, Inc. Acides nucleiques et proteines correspondantes connues sous 251p5g2 que l'on utilise dans le traitement et la detection de cancers
TW200413539A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Genes and polypeptides relating to prostate cancers
WO2004033687A1 (fr) * 2002-10-11 2004-04-22 Yamanouchi Pharmaceutical Co., Ltd. Procede de criblage d'un medicament contre l'insuffisance renale
AU2003302386B2 (en) * 2002-11-26 2010-04-01 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
EP1589110A4 (fr) * 2002-12-27 2006-06-07 Nat Inst Of Advanced Ind Scien Glycosyltransferase, acide nucleique codant ladite glycosyltransferase et methode de test de cancerisation a l'aide dudit acide nucleique
GB0315827D0 (en) * 2003-07-05 2003-08-13 Imp College Innovations Ltd Methods
US20080274975A1 (en) * 2004-04-12 2008-11-06 The Trustees Of Columbia University In The City Of New Yourk Methods and Compositions for Inhibiting Abad/Abeta Protein Interaction
EP1627922A1 (fr) * 2004-08-18 2006-02-22 Sanofi-Aventis Deutschland GmbH Méthode de sélection d'agonistes et d'antagonistes du transporteur de carnitine et son utilisation
GB0423126D0 (en) * 2004-10-18 2004-11-17 Ares Trading Sa Protein
US7727725B2 (en) 2006-04-27 2010-06-01 Celera Corporation Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
WO2008070090A2 (fr) 2006-12-05 2008-06-12 Oncomed Pharmaceuticals, Inc. Compositions et procédés pour diagnostiquer et traiter un cancer
US20110250218A1 (en) * 2008-10-29 2011-10-13 Fong Lawrence H Disease-Associated Antigens and Methods of Use Thereof
US8637249B2 (en) 2008-11-14 2014-01-28 Gen-Probe Incorporated Compositions, kits and methods for detection of Campylobacter nucleic acid
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
EP2552947A4 (fr) * 2010-03-26 2013-11-13 Dartmouth College Vista, une protéine médiatrice régulatrice des lymphocytes t, agents de liaison à vista et utilisation associée
AU2011305655B2 (en) 2010-09-22 2015-11-05 Alios Biopharma, Inc. Substituted nucleotide analogs
EP2794630A4 (fr) 2011-12-22 2015-04-01 Alios Biopharma Inc Analogues de nucléotide phosphorothioate substitués
WO2013142124A1 (fr) 2012-03-21 2013-09-26 Vertex Pharmaceuticals Incorporated Formes solides d'un promédicament nucléotidique thiophosphoramidate
US9012427B2 (en) 2012-03-22 2015-04-21 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
EP2892558B1 (fr) 2012-09-07 2019-04-10 The Trustees Of Dartmouth College Modulateurs vista de diagnostic et de traitement de cancer
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
ES2920677T3 (es) 2013-12-24 2022-08-08 Janssen Pharmaceutica Nv Anticuerpos y fragmentos anti-VISTA
EP3154585B1 (fr) 2014-06-11 2022-02-23 Kathy A. Green Utilisation d'antagonistes et d'agonistes vista pour supprimer ou améliorer l'immunité humorale
AU2015357463B2 (en) 2014-12-05 2021-10-07 Immunext, Inc. Identification of VSIG8 as the putative vista receptor and its use thereof to produce vista/VSIG8 modulators
CN107922497B (zh) 2015-06-24 2022-04-12 詹森药业有限公司 抗vista抗体和片段
TWI756204B (zh) 2016-02-12 2022-03-01 比利時商楊森製藥公司 抗ｖｉｓｔａ抗體及片段、其用途及鑑定其之方法
CN118108843A (zh) 2016-04-15 2024-05-31 伊穆奈克斯特股份有限公司 抗人vista抗体及其用途
WO2020006108A2 (fr) * 2018-06-26 2020-01-02 Duke University Récepteurs odorants synthétiques
CN110714017B (zh) * 2019-11-06 2023-09-01 河南师范大学 锦鲤ptps基因、编码蛋白及应用
CN111621525B (zh) * 2020-06-18 2021-04-23 中赛干细胞基因工程有限公司 Stx1b基因在促进人脂肪间充质干细胞生长和分化中的用途
CN114317732B (zh) * 2021-04-08 2023-08-18 博尔诚（北京）科技有限公司 用于肺癌筛查的组合物及其应用

Also Published As

Publication number Publication date
WO2002079449A3 (fr) 2003-03-20
WO2002097031A3 (fr) 2005-05-12
AU2002344208A8 (en) 2005-11-17
EP1383894A2 (fr) 2004-01-28
WO2002079449A2 (fr) 2002-10-10
AU2002338265A1 (en) 2002-10-15
AU2002344208A1 (en) 2002-12-09
CA2442705A1 (fr) 2002-12-05
WO2002097031A2 (fr) 2002-12-05

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FZDE Discontinued