WO2002040715A8 - Molecules permettant la detection et le traitement de maladies - Google Patents

Molecules permettant la detection et le traitement de maladies

Info

Publication number
WO2002040715A8
WO2002040715A8 PCT/US2001/027628 US0127628W WO0240715A8 WO 2002040715 A8 WO2002040715 A8 WO 2002040715A8 US 0127628 W US0127628 W US 0127628W WO 0240715 A8 WO0240715 A8 WO 0240715A8
Authority
WO
WIPO (PCT)
Prior art keywords
mddt
provides
disease detection
treatment
molecules
Prior art date
Application number
PCT/US2001/027628
Other languages
English (en)
Other versions
WO2002040715A3 (fr
WO2002040715A2 (fr
Inventor
Stuart Jackson
Stephen E Lincoln
Christina M Altus
Gerard E Dufour
Michael S Chalup
Original Assignee
Incyte Genomics Inc
Stuart Jackson
Stephen E Lincoln
Christina M Altus
Gerard E Dufour
Michael S Chalup
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Stuart Jackson, Stephen E Lincoln, Christina M Altus, Gerard E Dufour, Michael S Chalup filed Critical Incyte Genomics Inc
Priority to AU2001287108A priority Critical patent/AU2001287108A1/en
Priority to EP01966607A priority patent/EP1343885A2/fr
Priority to CA002420983A priority patent/CA2420983A1/fr
Priority to US10/363,829 priority patent/US20040142331A1/en
Publication of WO2002040715A2 publication Critical patent/WO2002040715A2/fr
Publication of WO2002040715A8 publication Critical patent/WO2002040715A8/fr
Publication of WO2002040715A3 publication Critical patent/WO2002040715A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des polynucléotides sous forme de molécules purifiées permettant la détection et le traitement de maladies (mddt). L'invention concerne également des polypeptides (MDDT) codés par ces mddt. L'invention concerne par ailleurs l'utilisation des éléments suivants dans des épreuves diagnostiques: mddt, ou compléments, oligonucléotides, ou fragments. L'invention concerne en outre des vecteurs et des cellules hôtes renfermant des mddt, pour l'expression des MDDT. L'invention concerne enfin l'utilisation de MDDT isolés et purifiés pour l'induction d'anticorps et le criblage de librairies de composés, l'utilisation d'anticorps anti-MDDT dans des épreuves diagnostiques, ainsi que des jeux ordonnés de microéchantillons et des procédés d'utilisation correspondants.
PCT/US2001/027628 2000-09-05 2001-09-05 Molecules permettant la detection et le traitement de maladies WO2002040715A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2001287108A AU2001287108A1 (en) 2000-09-05 2001-09-05 Molecules for disease detection and treatment
EP01966607A EP1343885A2 (fr) 2000-09-05 2001-09-05 Molecules pour detection de maladie et traitement
CA002420983A CA2420983A1 (fr) 2000-09-05 2001-09-05 Molecules permettant la detection et le traitement de maladies
US10/363,829 US20040142331A1 (en) 2001-09-05 2001-09-05 Molecules for disease detection and treatment

Applications Claiming Priority (46)

Application Number Priority Date Filing Date Title
US23058300P 2000-09-05 2000-09-05
US22974700P 2000-09-05 2000-09-05
US22974900P 2000-09-05 2000-09-05
US22974800P 2000-09-05 2000-09-05
US22975000P 2000-09-05 2000-09-05
US22975100P 2000-09-05 2000-09-05
US60/229,751 2000-09-05
US60/229,747 2000-09-05
US60/230,583 2000-09-05
US60/229,748 2000-09-05
US60/229,750 2000-09-05
US60/229,749 2000-09-05
US23098900P 2000-09-06 2000-09-06
US23051900P 2000-09-06 2000-09-06
US23059500P 2000-09-06 2000-09-06
US23051700P 2000-09-06 2000-09-06
US23086500P 2000-09-06 2000-09-06
US23059700P 2000-09-06 2000-09-06
US23050500P 2000-09-06 2000-09-06
US23051500P 2000-09-06 2000-09-06
US23098800P 2000-09-06 2000-09-06
US23051400P 2000-09-06 2000-09-06
US23059900P 2000-09-06 2000-09-06
US23061000P 2000-09-06 2000-09-06
US23059800P 2000-09-06 2000-09-06
US23051800P 2000-09-06 2000-09-06
US60/230,519 2000-09-06
US60/230,597 2000-09-06
US60/230,515 2000-09-06
US60/230,865 2000-09-06
US60/230,517 2000-09-06
US60/230,595 2000-09-06
US60/230,610 2000-09-06
US60/230,598 2000-09-06
US60/230,514 2000-09-06
US60/230,505 2000-09-06
US60/230,989 2000-09-06
US60/230,518 2000-09-06
US60/230,599 2000-09-06
US60/230,988 2000-09-06
US23095100P 2000-09-07 2000-09-07
US23116300P 2000-09-07 2000-09-07
US23116700P 2000-09-07 2000-09-07
US60/230,951 2000-09-07
US60/231,167 2000-09-07
US60/231,163 2000-09-07

Publications (3)

Publication Number Publication Date
WO2002040715A2 WO2002040715A2 (fr) 2002-05-23
WO2002040715A8 true WO2002040715A8 (fr) 2002-10-24
WO2002040715A3 WO2002040715A3 (fr) 2003-07-17

Family

ID=27586707

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/027628 WO2002040715A2 (fr) 2000-09-05 2001-09-05 Molecules permettant la detection et le traitement de maladies

Country Status (3)

Country Link
EP (1) EP1343885A2 (fr)
CA (1) CA2420983A1 (fr)
WO (1) WO2002040715A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078205B2 (en) 2000-02-17 2006-07-18 Millennium Pharmaceuticals, Inc. Nucleic acid sequences encoding melanoma associated antigen molecules, aminotransferase molecules, atpase molecules, acyltransferase molecules, pyridoxal-phosphate dependent enzyme molecules and uses therefor
US20020106770A1 (en) * 2000-07-20 2002-08-08 Millennium Pharmaceuticals, Inc. 25233, a novel human aminotransferase and uses therefor
WO2002014483A2 (fr) * 2000-08-15 2002-02-21 Zymogenetics Inc Adenosine deaminase humaine
US6706513B2 (en) 2000-08-21 2004-03-16 Bristol-Myers Squibb Company Adenosine deaminase homolog
AU2002224331A1 (en) * 2000-09-22 2002-04-02 Incyte Genomics, Inc. Transcription factors and zinc finger proteins
US20030009017A1 (en) * 2000-11-08 2003-01-09 Leiby Kevin R. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
AU2002249816A1 (en) * 2000-12-15 2002-07-24 Millennium Pharmaceuticals, Inc. Human sugar transporter proteins, potassium channel proteins, phospholipid transporter proteins and methods of use thereof
US6989441B2 (en) 2001-02-15 2006-01-24 Millennium Pharmaceuticals, Inc. 25466, a human transporter family member and uses therefor
EP1464651A1 (fr) * 2003-04-03 2004-10-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Protéine associée à la distrophine (Drop1) utilisée comme marqueur por le cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2582897A (en) * 1996-03-15 1997-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
US6262249B1 (en) * 1998-06-23 2001-07-17 Chiron Corporation Pancreatic cancer genes
JP2002526777A (ja) * 1998-10-06 2002-08-20 ジョージタウン ユニバーシティ プレイオトロフィン検出法
EP1074617A3 (fr) * 1999-07-29 2004-04-21 Research Association for Biotechnology Amorces pour la synthèse de cADN de pleine longueur et leur utilisation

Also Published As

Publication number Publication date
EP1343885A2 (fr) 2003-09-17
WO2002040715A3 (fr) 2003-07-17
CA2420983A1 (fr) 2002-05-23
WO2002040715A2 (fr) 2002-05-23

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