WO2001097774A3 - Neue pharmazeutische zusammensetzung zur topischen anwendung von wasserunlöslichen und/oder schwer wasserlöslichen wirkstoffen - Google Patents

Neue pharmazeutische zusammensetzung zur topischen anwendung von wasserunlöslichen und/oder schwer wasserlöslichen wirkstoffen Download PDF

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Publication number
WO2001097774A3
WO2001097774A3 PCT/EP2001/007036 EP0107036W WO0197774A3 WO 2001097774 A3 WO2001097774 A3 WO 2001097774A3 EP 0107036 W EP0107036 W EP 0107036W WO 0197774 A3 WO0197774 A3 WO 0197774A3
Authority
WO
WIPO (PCT)
Prior art keywords
water
pharmaceutical composition
insoluble
topical application
soluble active
Prior art date
Application number
PCT/EP2001/007036
Other languages
English (en)
French (fr)
Other versions
WO2001097774A2 (de
Inventor
Norbert Kloecker
Original Assignee
Audit Inst For Medical Service
Norbert Kloecker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Audit Inst For Medical Service, Norbert Kloecker filed Critical Audit Inst For Medical Service
Priority to AU83876/01A priority Critical patent/AU8387601A/en
Publication of WO2001097774A2 publication Critical patent/WO2001097774A2/de
Publication of WO2001097774A3 publication Critical patent/WO2001097774A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Abstract

Die Erfindung betrifft eine pharmazeutische Zusammensetzung zur topischen Anwendung am Auge, bestehend aus mindestens einem wasserunlöslichen oder schwer wasserlöslichen Wirkstoff, welcher in Neutralöl gelöst vorliegt. Die Zusammensetzung ist sterilfiltrierbar und stabil. Die Applikation dieser erfindungsgemässen pharmazeutischen Zusammensetzung kann ohne Zusatz von Konservierungsmitteln und/oder Emulgatoren mittels Vorrichtungen, die eine genau definierte Dosierung erzeugen, in das Auge und auf die umgebenden Schleimhäute und Gewebe appliziert werden.
PCT/EP2001/007036 2000-06-21 2001-06-21 Neue pharmazeutische zusammensetzung zur topischen anwendung von wasserunlöslichen und/oder schwer wasserlöslichen wirkstoffen WO2001097774A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU83876/01A AU8387601A (en) 2000-06-21 2001-06-21 Novel pharmaceutical composition for the topical application of water-insoluble and/or hardly water-soluble active agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2000130378 DE10030378A1 (de) 2000-06-21 2000-06-21 Neue pharmazeutische Zusammensetzung zur topischen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen
DE10030378.1 2000-06-21

Publications (2)

Publication Number Publication Date
WO2001097774A2 WO2001097774A2 (de) 2001-12-27
WO2001097774A3 true WO2001097774A3 (de) 2002-06-20

Family

ID=7646397

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007036 WO2001097774A2 (de) 2000-06-21 2001-06-21 Neue pharmazeutische zusammensetzung zur topischen anwendung von wasserunlöslichen und/oder schwer wasserlöslichen wirkstoffen

Country Status (3)

Country Link
AU (1) AU8387601A (de)
DE (1) DE10030378A1 (de)
WO (1) WO2001097774A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20012565A (fi) * 2001-12-21 2003-06-22 Eero Mervaala Immunosuppressiivisessa terapiassa käytettäviä tuotteita
ES2295647T3 (es) * 2002-07-15 2008-04-16 Alcon, Inc. Composiciones de implante farmaceuticas lipofilas, no polimeras, para uso intraocular.
BR112020022083A2 (pt) * 2018-05-01 2021-02-02 Chibi, Inc. depot líquido, estojo e método para tratar a retina.
KR20210003877A (ko) * 2018-05-01 2021-01-12 치비 인코포레이티드 약제를 눈에 비침습적으로 지속 전달하기 위한 액체 데포

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2228198A (en) * 1989-02-20 1990-08-22 Sandoz Ltd Orally administrable cyclosporin solutions
EP0391369A2 (de) * 1989-04-05 1990-10-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Arzneiemulsionen
EP0521799A1 (de) * 1991-07-05 1993-01-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Augenarzneimittel
US5589455A (en) * 1994-12-28 1996-12-31 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
US5652212A (en) * 1984-07-24 1997-07-29 Cavanak; Thomas Cyclosporin galenic forms
US5660858A (en) * 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
WO1999049848A1 (en) * 1998-04-01 1999-10-07 Rtp Pharma Inc. Anticancer compositions
US5993846A (en) * 1993-08-13 1999-11-30 Pharmos Corporation Bioadhesive emulsion preparations for enhanced drug delivery
DE19925290A1 (de) * 1999-06-02 2000-12-07 Hexal Ag Neue pharmazeutische Zusammensetzung zur nasalen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4417038A1 (de) * 1994-05-14 1995-11-16 Carl Heinrich Dr Weischer Ester des Retinols (Vitamin A) und deren Herstellung und Verwendung als Arzneimittel und Kosmetika

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652212A (en) * 1984-07-24 1997-07-29 Cavanak; Thomas Cyclosporin galenic forms
GB2228198A (en) * 1989-02-20 1990-08-22 Sandoz Ltd Orally administrable cyclosporin solutions
EP0391369A2 (de) * 1989-04-05 1990-10-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Arzneiemulsionen
EP0521799A1 (de) * 1991-07-05 1993-01-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Augenarzneimittel
US5993846A (en) * 1993-08-13 1999-11-30 Pharmos Corporation Bioadhesive emulsion preparations for enhanced drug delivery
US5589455A (en) * 1994-12-28 1996-12-31 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
US5660858A (en) * 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
WO1999049848A1 (en) * 1998-04-01 1999-10-07 Rtp Pharma Inc. Anticancer compositions
DE19925290A1 (de) * 1999-06-02 2000-12-07 Hexal Ag Neue pharmazeutische Zusammensetzung zur nasalen Anwendung von wasserunlöslichen und/oder schwer wasserlöslichen Wirkstoffen

Also Published As

Publication number Publication date
WO2001097774A2 (de) 2001-12-27
DE10030378A1 (de) 2002-03-14
AU8387601A (en) 2002-01-02

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