WO2001094537A3 - Novel polypeptide--human nadh ubiquinone oxidoreductase 21.89 and polynucleotide encoding it - Google Patents

Novel polypeptide--human nadh ubiquinone oxidoreductase 21.89 and polynucleotide encoding it Download PDF

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Publication number
WO2001094537A3
WO2001094537A3 PCT/CN2001/000854 CN0100854W WO0194537A3 WO 2001094537 A3 WO2001094537 A3 WO 2001094537A3 CN 0100854 W CN0100854 W CN 0100854W WO 0194537 A3 WO0194537 A3 WO 0194537A3
Authority
WO
WIPO (PCT)
Prior art keywords
ubiquinone oxidoreductase
polynucleotide encoding
human nadh
nadh ubiquinone
polypeptide
Prior art date
Application number
PCT/CN2001/000854
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001094537A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU89496/01A priority Critical patent/AU8949601A/en
Publication of WO2001094537A2 publication Critical patent/WO2001094537A2/en
Publication of WO2001094537A3 publication Critical patent/WO2001094537A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention concerns a human NADH ubiquinone oxidoreductase 21.89 and polynucleotide encoding it. The invention also concerns the process of producing the polypeptide by recombinant DNA technique. The methods for treating many diseases e.g. Down Syndrome, dementia, tumours, developmental disorders, inflammation and immunological diseases etc. utilizing the polypeptide are disclosed. The invention also discloses the antagonist against the polypeptide and the therapeutics thereof. The invention also discloses the uses of the polynucleotide which encodes human NADH ubiquinone oxidoreductase 21.89.
PCT/CN2001/000854 2000-05-24 2001-05-21 Novel polypeptide--human nadh ubiquinone oxidoreductase 21.89 and polynucleotide encoding it WO2001094537A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU89496/01A AU8949601A (en) 2000-05-24 2001-05-21 A novel polypeptide, a human nadh-ubiquinone oxidoreductase 21.89 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 00115843 CN1324938A (en) 2000-05-24 2000-05-24 New polypeptide human HADH ubiquinone oxide-reductase 21.89 and polynucleotides for encoding same

Publications (2)

Publication Number Publication Date
WO2001094537A2 WO2001094537A2 (en) 2001-12-13
WO2001094537A3 true WO2001094537A3 (en) 2004-04-08

Family

ID=4585285

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000854 WO2001094537A2 (en) 2000-05-24 2001-05-21 Novel polypeptide--human nadh ubiquinone oxidoreductase 21.89 and polynucleotide encoding it

Country Status (3)

Country Link
CN (1) CN1324938A (en)
AU (1) AU8949601A (en)
WO (1) WO2001094537A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114591926B (en) * 2022-04-02 2024-02-13 南开大学 Purification method of humanized respiratory chain compound I

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999047666A1 (en) * 1998-03-18 1999-09-23 Shanghai Second Medical University Human ci-mnll homolog gene: cbfbmd04
CN1261104A (en) * 1999-01-20 2000-07-26 复旦大学 Human oxido-reductase subunit and its coding sequence, preparing process and application

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999047666A1 (en) * 1998-03-18 1999-09-23 Shanghai Second Medical University Human ci-mnll homolog gene: cbfbmd04
CN1261104A (en) * 1999-01-20 2000-07-26 复旦大学 Human oxido-reductase subunit and its coding sequence, preparing process and application

Also Published As

Publication number Publication date
AU8949601A (en) 2001-12-17
WO2001094537A2 (en) 2001-12-13
CN1324938A (en) 2001-12-05

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