WO2001075031A3 - Novel polypeptide - a human gonadotropin-releasing hormone 12 andpolynucleotide encoding it - Google Patents
Novel polypeptide - a human gonadotropin-releasing hormone 12 andpolynucleotide encoding it Download PDFInfo
- Publication number
- WO2001075031A3 WO2001075031A3 PCT/CN2001/000392 CN0100392W WO0175031A3 WO 2001075031 A3 WO2001075031 A3 WO 2001075031A3 CN 0100392 W CN0100392 W CN 0100392W WO 0175031 A3 WO0175031 A3 WO 0175031A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- releasing hormone
- human gonadotropin
- encoding
- andpolynucleotide
- polypeptide
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 239000000579 Gonadotropin-Releasing Hormone Substances 0.000 title abstract 3
- 101000857870 Squalus acanthias Gonadoliberin Proteins 0.000 title abstract 3
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 title abstract 3
- 229940035638 gonadotropin-releasing hormone Drugs 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention concerns a human gonadotropin-releasing hormone 12 and polynucleotide encoding it. The invention also concerns the process of producing the polypeptide by recombinant DNA technique.The methods for treating many diseases e.g. malignant tumour, hemopathy, infection of HIV, immunological diseases and a variety ofinflammation etc. utilizing the polypeptide are disclosed. The invention discloses the antagonist against the polypeptide and therapeutics thereof. The invention also discloses the uses of the polynucleotide, which encodes a human gonadotropin-releasing hormone.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU58148/01A AU5814801A (en) | 2000-03-24 | 2001-03-23 | A novel polypeptide, human thyrotropine 12 and the polynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00115108 CN1315354A (en) | 2000-03-24 | 2000-03-24 | Polypeptide-human gonadotropin-releasing homone 12 and polynucleotide for coding it |
| CN00115108.8 | 2000-03-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001075031A2 WO2001075031A2 (en) | 2001-10-11 |
| WO2001075031A3 true WO2001075031A3 (en) | 2002-02-21 |
Family
ID=4584577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000392 WO2001075031A2 (en) | 2000-03-24 | 2001-03-23 | Novel polypeptide - a human gonadotropin-releasing hormone 12 andpolynucleotide encoding it |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1315354A (en) |
| AU (1) | AU5814801A (en) |
| WO (1) | WO2001075031A2 (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788178A (en) * | 1984-04-18 | 1988-11-29 | Hoechst Aktiengesellschaft | Use of gonadoliberin and gonadoliberin agonists for the treatment of climacteric complaints |
| US5091367A (en) * | 1986-10-09 | 1992-02-25 | Hoechst Aktiengesellschaft | Analogs of gonadoliberin with improved solubility, methods for their preparation, agents containing them and their use |
-
2000
- 2000-03-24 CN CN 00115108 patent/CN1315354A/en active Pending
-
2001
- 2001-03-23 AU AU58148/01A patent/AU5814801A/en not_active Abandoned
- 2001-03-23 WO PCT/CN2001/000392 patent/WO2001075031A2/en active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4788178A (en) * | 1984-04-18 | 1988-11-29 | Hoechst Aktiengesellschaft | Use of gonadoliberin and gonadoliberin agonists for the treatment of climacteric complaints |
| US5091367A (en) * | 1986-10-09 | 1992-02-25 | Hoechst Aktiengesellschaft | Analogs of gonadoliberin with improved solubility, methods for their preparation, agents containing them and their use |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1315354A (en) | 2001-10-03 |
| AU5814801A (en) | 2001-10-15 |
| WO2001075031A2 (en) | 2001-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2001075031A3 (en) | Novel polypeptide - a human gonadotropin-releasing hormone 12 andpolynucleotide encoding it | |
| WO2001075047A3 (en) | Novel polypeptide - a human flavoprotein sununit 10 and polynucleotide encoding it | |
| WO2001094539A3 (en) | A human kaza1 inhibitory factor 11 and polynucleotide encoding it | |
| WO2001075013A3 (en) | Novel polypeptide - a human cyclin dependent kinase 14 and polynucleotide encoding it | |
| WO2001075017A3 (en) | Novel polypeptide, a human carbamylaspartic dehydrase 17 and the polynucleotide encoding it | |
| WO2001083686A3 (en) | Novel polypeptide, a human inclusion-like protein 9 and polynucleotide encoding it | |
| WO2001074998A3 (en) | Novel polypeptide - a human protein hydrolytic enzyme regulatory protein 10 and polynucleotide encoding it | |
| WO2001079437A3 (en) | Novel polypeptide a human cell differential transcriptional factor 14 and polynucleotide encoding it | |
| WO2001094529A3 (en) | A novel polypeptide, a human atp dependant serine proteinase 21 and the polynucleotide encoding the polypeptide | |
| WO2001081535A3 (en) | A novel polypeptide, a human pax protein 9.9 and the polynucleotide encoding the polypeptide | |
| WO2001094537A3 (en) | Novel polypeptide--human nadh ubiquinone oxidoreductase 21.89 and polynucleotide encoding it | |
| WO2001074997A3 (en) | Novel polypeptide - a human cannabis alcohol receptor protein 11 and polynucleotide encoding it | |
| WO2001075036A3 (en) | A novel polypeptide, human immunophiline 14 and the polynucleotide encoding the polypeptide | |
| WO2001075061A3 (en) | A novel polypeptide, cdv-1-42 and the polynucleotide encoding the polypeptide | |
| WO2001083687A3 (en) | A novel polypeptide, a human pax protein 23 and the polynucleotide encoding the polypeptide | |
| WO2001066585A8 (en) | A new polypeptide-human protease regulatory protein 10 and the p olynucleotide encoding it | |
| WO2001075011A3 (en) | A novel polypeptide, cytochrome human constitution protein 10 and the polynucleotide encoding the polypeptide | |
| WO2001075041A3 (en) | A novel polypeptide-human epilepsy-associated protein 11 and the polynucleotide encoding said polypeptide | |
| WO2001094532A3 (en) | A novel polypeptide, ribosomal protein l39 9 and the polynucleotide encoding the polypeptide | |
| WO2002000832A3 (en) | A novel polypeptide--a p80-coilin protein 8.8 and the polynucleotide encoding this novel polypeptide | |
| WO2001064866A1 (en) | A novel polypeptide, a ribosome s19e protein 11 and the polynucleotide encoding the polypeptide | |
| WO2002000821A3 (en) | A novel polypeptide, a human protein plp39 and the polynucleotide encoding the polypeptide | |
| WO2001079427A3 (en) | A novel polypeptide, a human ion channel 9 for chlorine and the polynucleotide encoding the polypeptide | |
| WO2001081536A3 (en) | A novel polypeptide, a human ysk1 kinase protein 10, and the polynucleotide encoding the polypeptide | |
| WO2001075060A3 (en) | A novel polypeptide, human cystein protease 9 and the polynucleotide encoding the polypeptide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| AK | Designated states |
Kind code of ref document: A3 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
| REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
| 122 | Ep: pct application non-entry in european phase | ||
| NENP | Non-entry into the national phase |
Ref country code: JP |