WO2001094539A3 - A human kaza1 inhibitory factor 11 and polynucleotide encoding it - Google Patents

A human kaza1 inhibitory factor 11 and polynucleotide encoding it Download PDF

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Publication number
WO2001094539A3
WO2001094539A3 PCT/CN2001/000872 CN0100872W WO0194539A3 WO 2001094539 A3 WO2001094539 A3 WO 2001094539A3 CN 0100872 W CN0100872 W CN 0100872W WO 0194539 A3 WO0194539 A3 WO 0194539A3
Authority
WO
WIPO (PCT)
Prior art keywords
human
inhibitory factor
polypeptide
polynucleotide encoding
kaza1
Prior art date
Application number
PCT/CN2001/000872
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001094539A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU89501/01A priority Critical patent/AU8950101A/en
Publication of WO2001094539A2 publication Critical patent/WO2001094539A2/en
Publication of WO2001094539A3 publication Critical patent/WO2001094539A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8135—Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention concerns a novel polypeptide--- a human Kasa1 type inhibitory factor 11 and polynucleotide encoding it. The invention also concerns the process of producing the polypeptide by recombinant DNA technique. The methods for treating many diseases e.g. malignant tumor, hemopathy, infection of HIV, immunological diseases and a variety of inflammation etc. utilizing the polypeptide are disclosed. The invention discloses the antagonist against the polypeptide and therapeutics thereof. The invention also discloses the uses of the polynucleotide, which encodes a human Kasal type inhibitory factor 11.
PCT/CN2001/000872 2000-05-26 2001-05-28 A human kaza1 inhibitory factor 11 and polynucleotide encoding it WO2001094539A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU89501/01A AU8950101A (en) 2000-05-26 2001-05-28 A novel polypeptide, a human kazal inhibition factor 11 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN 00115897 CN1325889A (en) 2000-05-26 2000-05-26 Polypeptide-human kazal-type inhibitor 11 and polynucleotide for coding it
CN00115897.X 2000-05-26

Publications (2)

Publication Number Publication Date
WO2001094539A2 WO2001094539A2 (en) 2001-12-13
WO2001094539A3 true WO2001094539A3 (en) 2002-03-14

Family

ID=4585339

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000872 WO2001094539A2 (en) 2000-05-26 2001-05-28 A human kaza1 inhibitory factor 11 and polynucleotide encoding it

Country Status (3)

Country Link
CN (1) CN1325889A (en)
AU (1) AU8950101A (en)
WO (1) WO2001094539A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993014122A1 (en) * 1992-01-07 1993-07-22 Novo Nordisk A/S A human kunitz-type protease inhibitor variant
US5532339A (en) * 1989-04-21 1996-07-02 Yamanouchi Pharmaceutical Co., Ltd. Fusion protein between human macif and a heterologous pi anchor domain

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532339A (en) * 1989-04-21 1996-07-02 Yamanouchi Pharmaceutical Co., Ltd. Fusion protein between human macif and a heterologous pi anchor domain
WO1993014122A1 (en) * 1992-01-07 1993-07-22 Novo Nordisk A/S A human kunitz-type protease inhibitor variant

Also Published As

Publication number Publication date
AU8950101A (en) 2001-12-17
CN1325889A (en) 2001-12-12
WO2001094539A2 (en) 2001-12-13

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