WO2001072322A2 - Administration parenterale de fortes doses de lactoferrine - Google Patents

Administration parenterale de fortes doses de lactoferrine Download PDF

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Publication number
WO2001072322A2
WO2001072322A2 PCT/NL2001/000253 NL0100253W WO0172322A2 WO 2001072322 A2 WO2001072322 A2 WO 2001072322A2 NL 0100253 W NL0100253 W NL 0100253W WO 0172322 A2 WO0172322 A2 WO 0172322A2
Authority
WO
WIPO (PCT)
Prior art keywords
lactoferrin
hlf
fragment
variant
heparin
Prior art date
Application number
PCT/NL2001/000253
Other languages
English (en)
Other versions
WO2001072322A3 (fr
Inventor
Johannes Bernardus Mathias Marie Van Bree
Johannes Henricus Nuijens
Original Assignee
Pharming Intellectual Property B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharming Intellectual Property B.V. filed Critical Pharming Intellectual Property B.V.
Priority to AU44865/01A priority Critical patent/AU4486501A/en
Publication of WO2001072322A2 publication Critical patent/WO2001072322A2/fr
Publication of WO2001072322A3 publication Critical patent/WO2001072322A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des méthodes de traitement utilisant de fortes doses de lactoferrine. La lactoferrine peut être administrée à fortes doses par voie parentérale sans effets secondaires importants pour traiter diverses affections, notamment des maladies infectieuses et l'inflammation.
PCT/NL2001/000253 2000-03-27 2001-03-27 Administration parenterale de fortes doses de lactoferrine WO2001072322A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU44865/01A AU4486501A (en) 2000-03-27 2001-03-27 High dosage parenteral administration of lactoferrin

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19335200P 2000-03-27 2000-03-27
EP00201110 2000-03-27
US60/193,352 2000-03-27
EP00201110.4 2000-03-27

Publications (2)

Publication Number Publication Date
WO2001072322A2 true WO2001072322A2 (fr) 2001-10-04
WO2001072322A3 WO2001072322A3 (fr) 2002-03-21

Family

ID=26072048

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2001/000253 WO2001072322A2 (fr) 2000-03-27 2001-03-27 Administration parenterale de fortes doses de lactoferrine

Country Status (2)

Country Link
AU (1) AU4486501A (fr)
WO (1) WO2001072322A2 (fr)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077239A1 (fr) * 2001-03-27 2002-10-03 Sumitomo Pharmaceuticals Company, Limited Polypeptides se liant au virus hcv
EP1360961A1 (fr) * 2002-05-07 2003-11-12 AM-Pharma B.V. Utilisation de peptides antibiotiques pour potentialiser l'activité des agents antimicrobiens
WO2004089986A1 (fr) * 2003-04-14 2004-10-21 Stichting Voor De Technische Wetenschappen Peptide antimicrobien de la famille des transferrines
US7034126B2 (en) 2003-05-14 2006-04-25 Agennix, Inc. Lactoferrin in the treatment of diabetes mellitus
EP1653987A2 (fr) * 2003-07-16 2006-05-10 The Research Foundation of the State University of New York Facteur x de defense de l'hote (hdfx)
US7183381B2 (en) 2004-10-26 2007-02-27 Agennix, Inc. Composition of lactoferrin related peptides and uses thereof
EP1993592A2 (fr) * 2006-02-21 2008-11-26 Ventria Bioscience Compositions contenant de la lactoferrine et leurs procédés d'utilisation pour favoriser la croissance de cellules cutanées
US7592306B2 (en) 2002-12-10 2009-09-22 Agennix, Inc. Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
US9050323B2 (en) * 2005-12-09 2015-06-09 Microbo S.R.L. Methods of treating destructive inflammation of the mucous membranes with lactoferrin
WO2017202172A1 (fr) * 2016-05-23 2017-11-30 成都福际生物科技有限公司 Domaine de liaison à l'adn de transferrine modifiée, adn polymérase recombinante et son procédé de préparation
CN112351791A (zh) * 2018-06-26 2021-02-09 S&K生物制药有限公司 糖胺聚糖抑制剂和促进剂
WO2020250209A3 (fr) * 2020-03-09 2021-02-18 Sofar S.P.A. Lactoferrine à usage oral ayant une action antivirale

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995030339A1 (fr) * 1994-05-05 1995-11-16 Ferrodynamics, Inc. Clonage, expression et utilisations de la lactoferrine humaine
WO1998033509A2 (fr) * 1997-02-03 1998-08-06 Pharming Intellectual Property Bv Proprietes utiles de la lactoferrine humaine et de variants de celle-ci
WO1999014231A2 (fr) * 1997-09-16 1999-03-25 Forssmann Wolf Georg Peptides bifidigenes
WO2001034641A2 (fr) * 1999-11-11 2001-05-17 Am-Pharma B.V. Activite antimicrobienne du premier groupe cationique de la lactoferrine humaine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3645282B2 (ja) * 1994-04-22 2005-05-11 森永乳業株式会社 ヘパリン中和剤
JP3506274B2 (ja) * 1994-09-01 2004-03-15 雪印乳業株式会社 新規ペプチドおよび免疫賦活剤

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995030339A1 (fr) * 1994-05-05 1995-11-16 Ferrodynamics, Inc. Clonage, expression et utilisations de la lactoferrine humaine
WO1998033509A2 (fr) * 1997-02-03 1998-08-06 Pharming Intellectual Property Bv Proprietes utiles de la lactoferrine humaine et de variants de celle-ci
WO1999014231A2 (fr) * 1997-09-16 1999-03-25 Forssmann Wolf Georg Peptides bifidigenes
WO2001034641A2 (fr) * 1999-11-11 2001-05-17 Am-Pharma B.V. Activite antimicrobienne du premier groupe cationique de la lactoferrine humaine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch, Week 199602 Derwent Publications Ltd., London, GB; Class B04, AN 1996-017144 XP002178978 & JP 07 291874 A (MORINAGA MILK IND CO LTD), 7 November 1995 (1995-11-07) *
DATABASE WPI Section Ch, Week 199621 Derwent Publications Ltd., London, GB; Class B04, AN 1996-205535 XP002178977 & JP 08 073499 A (SNOW BRAND MILK PROD CO LTD), 19 March 1996 (1996-03-19) *

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002077239A1 (fr) * 2001-03-27 2002-10-03 Sumitomo Pharmaceuticals Company, Limited Polypeptides se liant au virus hcv
EP1360961A1 (fr) * 2002-05-07 2003-11-12 AM-Pharma B.V. Utilisation de peptides antibiotiques pour potentialiser l'activité des agents antimicrobiens
US7592306B2 (en) 2002-12-10 2009-09-22 Agennix, Inc. Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
US8058234B2 (en) 2002-12-10 2011-11-15 Agennix Incorporated Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
WO2004089986A1 (fr) * 2003-04-14 2004-10-21 Stichting Voor De Technische Wetenschappen Peptide antimicrobien de la famille des transferrines
US7034126B2 (en) 2003-05-14 2006-04-25 Agennix, Inc. Lactoferrin in the treatment of diabetes mellitus
US7262279B2 (en) * 2003-05-14 2007-08-28 Agennix, Inc. Lactoferrin in the treatment of diabetes mellitus
EP1653987A2 (fr) * 2003-07-16 2006-05-10 The Research Foundation of the State University of New York Facteur x de defense de l'hote (hdfx)
EP1653987A4 (fr) * 2003-07-16 2006-08-09 Univ New York State Res Found Facteur x de defense de l'hote (hdfx)
US7420033B2 (en) 2004-10-26 2008-09-02 Agennix, Inc. Composition of lactoferrin related peptides and uses thereof
US7183381B2 (en) 2004-10-26 2007-02-27 Agennix, Inc. Composition of lactoferrin related peptides and uses thereof
US9050323B2 (en) * 2005-12-09 2015-06-09 Microbo S.R.L. Methods of treating destructive inflammation of the mucous membranes with lactoferrin
EP1993592A2 (fr) * 2006-02-21 2008-11-26 Ventria Bioscience Compositions contenant de la lactoferrine et leurs procédés d'utilisation pour favoriser la croissance de cellules cutanées
EP1993592A4 (fr) * 2006-02-21 2011-11-16 Ventria Bioscience Compositions contenant de la lactoferrine et leurs procédés d'utilisation pour favoriser la croissance de cellules cutanées
WO2017202172A1 (fr) * 2016-05-23 2017-11-30 成都福际生物科技有限公司 Domaine de liaison à l'adn de transferrine modifiée, adn polymérase recombinante et son procédé de préparation
US11053479B2 (en) 2016-05-23 2021-07-06 Foregene Company Limited Modified transferrin DNA binding domain, recombinant DNA polymerase and preparation method
CN112351791A (zh) * 2018-06-26 2021-02-09 S&K生物制药有限公司 糖胺聚糖抑制剂和促进剂
WO2020250209A3 (fr) * 2020-03-09 2021-02-18 Sofar S.P.A. Lactoferrine à usage oral ayant une action antivirale
WO2021181276A1 (fr) * 2020-03-09 2021-09-16 Sofar S.P.A. Composition comprenant de la lactoferrine et des souches bactériennes probiotiques pour une utilisation orale avec action antivirale

Also Published As

Publication number Publication date
WO2001072322A3 (fr) 2002-03-21
AU4486501A (en) 2001-10-08

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