WO2001064211A1 - Médicament spécifique pour le traitement du sida - Google Patents

Médicament spécifique pour le traitement du sida Download PDF

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WO2001064211A1
WO2001064211A1 PCT/CN2000/000043 CN0000043W WO0164211A1 WO 2001064211 A1 WO2001064211 A1 WO 2001064211A1 CN 0000043 W CN0000043 W CN 0000043W WO 0164211 A1 WO0164211 A1 WO 0164211A1
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Prior art keywords
parts
vitamin
aids
patients
acid
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PCT/CN2000/000043
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English (en)
Chinese (zh)
Inventor
Shu-Wen Lee
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Lee Shu Wen
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Priority to PCT/CN2000/000043 priority Critical patent/WO2001064211A1/fr
Priority to CNB008189420A priority patent/CN1213747C/zh
Priority to AU2000231423A priority patent/AU2000231423A1/en
Publication of WO2001064211A1 publication Critical patent/WO2001064211A1/fr
Priority to HK02107734.4A priority patent/HK1046848B/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Definitions

  • the invention relates to a special-effect medicine for treating AIDS, which is also called AIDS RECOVERY DRUG (referred to as ARD).
  • ARD AIDS RECOVERY DRUG
  • AIDS is a kind of extremely rapid infection that has only been discovered in the last two or three decades.
  • the patient is the most painful and has the widest transmission route. It is the century's black death with a 100% mortality rate in human history.
  • the virus Once infected, the virus first enters the liver.
  • the liver uses the rich nutrition of the liver to continuously replicate the virus at a very high speed, and then the replicated virus is continuously transferred to the tissues and organs of the whole body through the circulatory system, and the organs are filled with X-rays.
  • the rotten and disgusting skin cancers appearing from the top of the head to the soles of the feet.
  • AIDS has the characteristics of highly toxic and uncontrolled drugs that have not been found in all diseases.
  • Symptoms such as a cold, such as an unending cough, sneezing, runny nose, lack of food, and all can return to normal within two days.
  • the whole body came out from the soreness in the bones. I was sleepy and wanted to sleep, but I could sleep for 4 or 5 hours on the day of taking the medicine, and I could sleep until dawn at the next day. The soreness and drowsiness disappeared completely.
  • the purpose of the present invention is to provide a medicine with low price, fast and reliable effect, and immediate and immediate treatment effect that can relieve the suffering of patients, and low-income patients can also afford a combination of symptoms and cures to make them unfortunately infected with AIDS.
  • Patients can get rid of the suffering of AIDS immediately after peony medicine.
  • the invention of this medicine can make AIDS gradually disappear from the world, so that people can enjoy the joy of heavenly sex without fear.
  • the AIDS-specific drug of the present invention may be a powder capsule, a tablet, an oral solution, or a freezing agent.
  • the drug composition and weight ratio of the drug are:
  • Vitamin A 0. 01-0. 04 servings
  • the present invention can be made by a conventional method.
  • DL-type methionine has strong detoxification, can inhibit the replication and regeneration of AIDS virus, and is one of the essential amino acids in the body.
  • the methyl group in its molecule interacts with hormones in the body to produce bile.
  • Fatty acids, glycerol, and phosphoric acid are converted into phospholipids to be absorbed by the body to strengthen liver function.
  • vitamin B group in the present invention can increase liver function and detoxification effect, and at the same time promote the utilization of carbohydrates by the body to prevent liver disease and sclerosis And the body's allergies caused by the release of histamine in the cells due to HIV, enhance physical strength, because the instantaneous time of HIV in the body increases thousands of times, a large amount of DL-type methionine must be given to inhibit HIV replication And, there must be a constant, long-lasting and sufficient drug to control the growth of HIV. After a long period of continuous and patient taking of drugs, in order to maintain sufficient drugs in the body to control the HIV virus no longer replicate, the HIV virus is extremely tenacious and highly resistant. It has special evasion treatment characteristics, so it must be taken patiently and patiently for a long time.
  • Silymarin It is produced by the natural plants Cardum Morianus, Si lybum Morianus
  • the active ingredient taken from the fruit is mild in medicine and easily absorbed by the human body.
  • This ingredient can strengthen the cell membrane, and has a strong protective effect on lipid liver cells and abnormal changes in the liver. It can reduce lipids, promote liver function, and accelerate liver.
  • the excretion of toxic substances due to the rapid accumulation of AIDS virus in the liver, and the use of DL-type methionine, can make the liver's avivirin can be decomposed and excreted faster;
  • silymarin in addition to its effective detoxification function It can also strengthen the liver cell membrane and protect the entire liver from being damaged by the virus with strong lethality. Because of this ingredient, it can inhibit the HIV virus from continuing to develop in the liver, which can completely destroy its virus production in the liver. Factory and development base for virus spread.
  • Lipoic acid amine is more than three times more potent than lipoic acid. It is a compound of Vitamin B14 and is easily absorbed by the stomach and intestines. It is a newer product in the Vitamin B group. It has been in the market for more than 40 years and has no side effects. The effect is significant. In order to protect the normal function of the liver, heart, kidney, brain and other body organs and tissues, it plays an extremely important role in the TCA Cycle, especially to protect the liver. The amount of animal starch in the liver has strong detoxification and anti-allergic effects. With V13, methionine, and silymarin, it significantly destroys the AIDS virus and replicates its amazing detoxification effect.
  • Bromphenimide maleate This agent is a chemically synthesized antihistamine that is suitable for relieving or preventing allergic symptoms, especially for allergies in the upper respiratory tract.
  • AIDS patients The common symptoms of AIDS patients are that the skin is prone to rashes, and then gradually rots, and the entire body is strangely itchy, coughing, runny, sneezing, sputum, can not stop for a while, can not be controlled, and people feel sick.
  • This symptom is The most important cause of the AIDS virus is that the AIDS virus invades into the cells of the body and releases histamine. Therefore, the allergic symptoms are aggravated by the amount of histamine released from the cells.
  • This allergic disease is not Malay Bromphenimide has no other treatment.
  • This medicine combined with Orotic Acid and Dexamethasone has general anti-inflammatory and anti-allergic effects. The three medicines are used in combination to complement each other, such as tiger wings, which are fatal to all dangerous symptoms of toxicity. All medicines can cure the disease, the effect is fast, and the function is remarkable. Second, anti-inflammatory and anti-allergic agents
  • Dexamethasone It is a parahormonal preparation, which has the advantages of five times the potency of similar drugs and very few side effects. In the amount of treatment, it is the one that can raise blood sugar in the same drug with minimal effect. It is the most effective anti-inflammatory and allergic treatment Good drug choice.
  • This medicine is effective for severe and fatal diseases and allergic dangerous diseases, such as acute rheumatic fever, sporadic lupus erythematosus, pemphigus, and nodular tumors. It is used in combination with DL-type methionine and Orotic Aeid to treat various skin diseases It has unexpected effects, so it can be cured in a few days by treating AIDS infections like warts and ringworm, and if it is well controlled, it will not recur like ringworm and warts. '
  • This medicine is an anti-inflammatory and anti-allergic preparation with strong effects and the lowest side effects.
  • This product is effective for allergic symptoms such as rhinitis, sneezing, runny nose, allergic bronchitis, accompanying cough, sputum, urticaria, Skin itching and other symptoms, the effect is rapid and long-lasting.
  • This agent has no hypnotic side effects of general antihistamines. It is used to treat various diseases such as AIDS, and has significant specific effects. Because of the above allergic syndrome, the symptoms that affect patients' inability to sleep are extremely fast. Eliminated, so sleep is sweet, do not need to take general sleeping pills, general sleeping pills after taking the sleepy side effects and the shortcomings of sleeping pills habits and dependence, and allergic conditions still can not receive the treatment effect. -
  • Vitamin A is an oil-soluble substance. He needs minerals and fats. He can be stored in the body and does not require daily supplementation. Patients with severe deficiency need to replenish for a long time. This agent has no side effects.
  • Vitamin A is an anti-ocular disease vitamin, AIDS patients Eyes gradually become blind due to blurring. Due to the supplementation of patients' vitamin A and clinical experience, vitamin A can indeed restore vision or slow down the patient's eyes in a short period of time. Therefore, the eyes of AIDS patients are blurred, and gradually become blind. .
  • Vitamin B1 It is a water-soluble vitamin. It is often used in the vitamin B group. Excess B1 in the human body will not be stored in the body, but will be completely excreted from the body. Therefore, it needs to be supplemented every day. B1 has supplements between the vitamins. Effect, patients with chronic AIDS diet and malnutrition need to increase the amount of B1, it can significantly increase appetite, such as with high-protein and high-calorie foods, can quickly supplement the body nutrition. Vitamin B1 is called spiritual vitamins. The nerves of AIDS patients may also be poisoned. It can prevent neuroinflammation, beriberi is effective, and help digestion, especially the digestion of carbohydrates. AIDS patients' food intake increases sharply after taking it.
  • vitamin B1 is an important adjuvant therapeutic agent for erosive skin diseases.
  • the AIDS virus spreads rapidly in the body. It is pervasive in all organs inside and outside the body. It is extremely destructive. It destroys the entire immune system, digestion, excretion, and respiratory system. It also destroys all immune systems. Of course, the nervous system is also immune. Patients also have general inflammation. After taking B1, not only can it help neuro-inflammatory treatment, but it can also help maintain mental tranquility, relax mood and relax normal functions.
  • Vitamin B2 is a water-soluble vitamin that is easy to digest and absorb. According to the needs of the body, the excess is excreted from the body. Like other vitamin B groups, it does not accumulate in the body. Supplements to maintain body needs. The difference between vitamin B1 and B2 is that B2 can be heat-resistant, acid-resistant, and oxidation-resistant. Its effect can promote skin health, nail health, and gloss enhancement, help eliminate inflammation of the lips, mouth, heart, and mouth, and increase appetite. To develop vitamins, this medicine contains B2 to supplement the lack of B2 to treat the upper and lower lips and mouth corners of the mouth of AIDS patients, and to make the hair that has fallen out of AIDS regenerate and be radiant.
  • Using it with VI can increase AIDS Patients have deteriorated blurred vision, reduce eye fatigue, RD A for adults is 1.2 mg to 1.6 mg, due to a large lack of AIDS patients, oral cavity The upper and lower tongues and the stomach and intestines have extremely severe inflammation. The thyroid, lymph node nodules, and internal tumors also work wonders. Therefore, a large amount of B2 must be supplemented.
  • the daily intake can reach 10-20 mg, which is more appropriate. It will be damaged by light, especially ultraviolet rays and alkaline substances. It should be stored in a dark place, and do not drink tea and coffee when taking medicine, so as not to reduce its efficacy. This drug is not toxic.
  • vitamin B2 is an indispensable best choice. After administration to AIDS patients, a large amount of administration of B2 can significantly improve the efficacy.
  • Nicotinamide, Vitamin3 In the human body, it can help the liver to use the main amino acid to absorb and process the functional personality variables that synthesize tryptophan into nicotinic acid.
  • Oxalic acid and pararenal corticosteroids and 'thyroid insulin belong to the same Sex hormone, (estrous hormone) progesterone, an indispensable component of testicular lipid synthesis, its effect is anti-dermatitis, it can help B1 and B2 promote carbohydrate metabolism, reduce gastrointestinal digestive disorders, promote digestion, prevent and alleviate AIDS patients Severe migraine, promote blood circulation, can quickly transfer AIDS treatment drugs to the whole body, immediately reduce the diarrhea and liver disease deterioration in AIDS patients, it can be used for vasodilation, hypertension and arteriosclerosis, so that the body digests food After fully generating energy, it can treat stomatitis and inflammation of the lips, prevent bad breath and reduce cholesterol. People who are particularly sensitive to the sun are often formed by the deficiency of V3 nicot
  • Vitamin B6 It is a water-soluble vitamin. After digestion, it will be excreted from the body in about eight hours. Like other vitamins, it is ingested in food and has a close relationship and coordination. It is an essential substance for the production of antibodies and blood cells. In the intestine, bacteria have the function of synthesizing B6. Containing fiber can provide the composition of B6 to promote the digestion and absorption of B12. It can digest and absorb proteins and fats. It can help the function of tryptophan vitamin B6, one of the main amino acids in the body.
  • Dermatitis helps Bl and B2 promote carbohydrate metabolism and promote nucleic acid synthesis to prevent aging, reduce muscle spasm at night, cramps in the feet, paralysis of the hands and feet, and nerve pain due to inflammation. When it is lacking, it can cause anemia, adipose dermatitis, glossitis, endoral inflammation, gastrointestinal disorders and vulgaris. It is also known as dermatitis vitamin. It is used to eliminate dermatitis and stomatitis and anemia. Has significant effects.
  • Folic acid This preparation is often used with liver preparations to treat malignant anemia.
  • the same therapeutic agent for liver diseases is an indispensable substance for the production of red blood cells and an important component of human cell proliferation.
  • the number of red blood cells and heme in patients taking this medicine increases rapidly, the bone marrow returns to normal, has analgesic effects, can increase appetite, and has an excellent appetite
  • Vitamin B12 Also known as red vitamins, it is used in very small amounts. The unit of dose calculation is meg per million grams. B12 is the only vitamin that contains minerals. It can promote the formation and regeneration of red blood cells, it can also increase appetite, increase physical strength, maintain the health of the nervous system, can make body fat, carbohydrates, proteins, provide physical use, it can eliminate irritability and depression, and improve mental concentration Force, attention. If V12 is lacking, it will lead to pernicious anemia and brain disorders. Patients with AIDS, because of inability to eat and sleep, and chronic malnutrition and insomnia, are extremely tired of B12, so B12 supplementation is given. B12 is safe and effective, and no toxicity report has been found so far.
  • B12 can strengthen blood and achieve the best results in a very short time, and it can quickly recover its vitality. Taking B12 during menstruation or before menstruation with vitamins can be beneficial to the body. Very good.
  • This formulation is formulated with B12, which has obvious effects on malnutrition and giant cell malignant anemia. It is the main component of intrahepatic blood supply and strong liver. First of all, the anemia status of AIDS patients can be significantly improved in a short period of time.
  • Vitamin B13 It has a precursor substance that causes nucleic acids and its role:
  • Orotic Acid can promote the growth and formation of starch in the human body.
  • Vitamin C Most animals can synthesize Vc in their own bodies, but humans, apes, gerbils, and others must be taken from food. C plays a major role in forming collagen. Collagen plays a major role in human tissue cells, Dental meat, vascular fractures, and tooth growth and repair are indispensable ingredients. It aids iron in the body, nosebleeds, hematuria for wasting diseases, light-sensitive dermatitis. He is also known as ascorbic vitamin.
  • Vitamin D3 This medicine is roughly the same as Vitamin D. It is used for vitamin D deficiency, such as rickets, osteoporosis or tetany; for pregnant women or lactating women, young children, etc., for the supply of vitamin D3. The amount should be greatly increased to avoid the above symptoms.
  • This vitamin is oil-soluble. It is derived from the fat in food and acts on the skin fat through sunlight and ultraviolet rays. It can make vitamin D3, which can be used by inhaling the body. If vitamin D is ingested from the mouth, the small intestine absorbs fat significantly. It is based on the International Unit of 1U. The dosage is very small. If the skin is burned by strong sun, the skin will stop producing vitamin D3.
  • Vitamin D3 can be obtained in cod liver oil, sardines, herring, salmon, catfish, milk and dairy products.
  • Calcium glycerol phosphate AIDS patients do not eat, severe water leakage, a large loss of calcium and quality, causing patients with limb weakness, walking on sticks, muscle spasms, hand and foot convulsions, causing measles, which will not heal over time. From allergic mange to dermatitis, this agent is taken for AIDS patients, and it can be absorbed quickly with vitamin D3. It can relieve mange and ringworm, and will not continue to scratch the skin. For internal calcium and phosphorus supplementation, the limbs and bones restore strength and no more cramps.
  • Bansanoic acid It is one of the vitamin B groups, which can help the formation and normal growth of cells, and make the central nervous system play an effective role in promoting the normal function of the prostate and the body. It turns fat into sugar and then energy indispensable substance. It is necessary for the synthesis of antibodies by the body to use p-aminobenzene (methane) acid and bile. It can be synthesized in the body by enterobacteria. Its effect: It can help wound healing, because it can make antibodies, so it can resist infectious diseases. This function is very important for AIDS patients. It can prevent fatigue and help AIDS patients feel tired all day. Help. If you have a lack of pancreatic acid, you may have hypoglycemia. Patients can also take food supplements such as fish liver, yolk, butter, butter, brown vegetable leaves, yellow vegetables, wheat germ, heart, beer, yeast, stone fruit Category, chicken and unrefined honey. The drug has so far not been found to be toxic.
  • Example 1 The AIDS specific medicine of the present invention is made into a powder capsule.
  • empirical blood proves, but it does not produce obvious characteristics in the liver and the body's appearance, and can be used in combination with pharmaceutical ingredients and weight ratios.
  • the conventional method is made as:
  • the medicine made according to this formula has a good effect of inhibiting the development of AIDS, and can gradually strengthen the body's immunity and make the body gradually recover.
  • Example 2 For most patients, there are obvious symptoms of AIDS, and drugs that can be used
  • Example 3 For severe patients, the symptoms of AIDS are very obvious, and the human body basically does not have any immunity ability.
  • the drug ingredients and weight ratios that can be used and made by conventional methods are:
  • This drug is not a new drug extracted from plants and animals or chemically developed. Because of its stable properties without any toxicity and side effects, this drug has been widely used in the medical community for decades.
  • the special AIDS treatment drugs disclosed in the present invention have very good curative effect on the treatment of AIDS patients.
  • the effectiveness of the above-mentioned various components has been proven through practical use, and the utility of the present invention should be beyond doubt;
  • the various ingredients and ratios of the ingredients disclosed in the present invention were not seen in publications before application, nor were they used publicly. In addition, they have the fact that the efficacy is enhanced as above. Therefore, the novelty and progress of the present invention have been If so, the company applies for an invention patent.

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Abstract

L'invention concerne une composition thérapeutique spécifique pour le traitement du sida sous forme de médicament du traitement du SIDA (MTS) susceptible de se présenter sous forme de capsules, de pastilles, de solution à administration par voie orale, par voie d'injection ou de gel. La composition du médicament est la suivante : DL-méthionine, silybine, thioctamine, maléate de bromophénéramine, dexaméthasone, vitamine A, nitrate de thiamine, ovoflavine, niacinamide, hydrochlorure de pyridoxine, acide folique, cyanocobalamine, vitamine C, glycérophosphate de calcium, acide « banduo » et vitamine D3. Ce médicament peut être obtenu à partir de procédés classiques.
PCT/CN2000/000043 2000-03-03 2000-03-03 Médicament spécifique pour le traitement du sida WO2001064211A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PCT/CN2000/000043 WO2001064211A1 (fr) 2000-03-03 2000-03-03 Médicament spécifique pour le traitement du sida
CNB008189420A CN1213747C (zh) 2000-03-03 2000-03-03 爱滋病特效药
AU2000231423A AU2000231423A1 (en) 2000-03-03 2000-03-03 Specific therapeutic composition for treating aids
HK02107734.4A HK1046848B (zh) 2000-03-03 2002-10-24 愛滋病特效藥

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2000/000043 WO2001064211A1 (fr) 2000-03-03 2000-03-03 Médicament spécifique pour le traitement du sida

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WO2001064211A1 true WO2001064211A1 (fr) 2001-09-07

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PCT/CN2000/000043 WO2001064211A1 (fr) 2000-03-03 2000-03-03 Médicament spécifique pour le traitement du sida

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CN (1) CN1213747C (fr)
AU (1) AU2000231423A1 (fr)
HK (1) HK1046848B (fr)
WO (1) WO2001064211A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1627663A3 (fr) * 2004-05-18 2006-03-15 Franco Deraco Utilisation d'une composition pharmaceutique pour le traitement de pathologies dérivées d'une infection par le virus de l'herpès, le virus de papillome, le virus de l'hépatite, la neuralgie virale, la dysplasie virale, les infections virales induites par une insuffisance immunitaire et la névrite virale
GB2427824A (en) * 2002-05-29 2007-01-10 Insignion Holdings Ltd Treatment of proliferative or viral conditions
WO2007065314A1 (fr) * 2005-12-08 2007-06-14 Pficker Pharmaceuticals, Ltd. Composition pour le traitement d'une hepatopathie virale
WO2015070280A1 (fr) * 2013-11-14 2015-05-21 Newsouth Innovations Pty Limited Senescence et phénotype sécrétoire associé à une senescence
FR3075037A1 (fr) * 2017-12-20 2019-06-21 Pierre Fabre Dermo-Cosmetique Association d'un retinoide et d'un extrait de silybum marianum (l.) gaertn
US11389469B2 (en) 2015-04-28 2022-07-19 Newsouth Innovations Pty Ltd Targeting NAD+ to treat chemotherapy and radiotherapy induced cognitive impairment, neuropathies and inactivity
RU2794229C2 (ru) * 2017-12-20 2023-04-13 Пьер Фабр Дермо-Косметик КОМБИНАЦИЯ РЕТИНОИДА И ЭКСТРАКТА Silybum marianum (L.) Gaertn

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EP0316117A1 (fr) * 1987-11-06 1989-05-17 Scienscope International N.V. Composés antiviraux, compositions contenant de tels composés et méthodes de traitement
WO1991003246A1 (fr) * 1989-09-11 1991-03-21 Wisconsin Alumni Research Foundation Nouvelle utilisation de composes de vitamine d afin d'inhiber la replication du virus du sida
DE4204102A1 (de) * 1992-02-12 1993-08-19 Kragler Peter Arzneimittel zur behandlung und/oder prophylaxe von aids und anderen verwandten erkrankungen
DE4204108A1 (de) * 1992-02-12 1993-08-19 Kragler Peter Arzneimittel zur behandlung und/oder prophylaxe von stoerungen des folat-stoffwechsels
EP0572922A1 (fr) * 1992-06-05 1993-12-08 ASTA Medica Aktiengesellschaft Combinaisons synergiques comprenant de l'acide lipoique et des vitamines dans des médicaments
CN1129113A (zh) * 1995-01-20 1996-08-21 赵汝熹 爱滋病特效治疗剂

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0316117A1 (fr) * 1987-11-06 1989-05-17 Scienscope International N.V. Composés antiviraux, compositions contenant de tels composés et méthodes de traitement
WO1991003246A1 (fr) * 1989-09-11 1991-03-21 Wisconsin Alumni Research Foundation Nouvelle utilisation de composes de vitamine d afin d'inhiber la replication du virus du sida
DE4204102A1 (de) * 1992-02-12 1993-08-19 Kragler Peter Arzneimittel zur behandlung und/oder prophylaxe von aids und anderen verwandten erkrankungen
DE4204108A1 (de) * 1992-02-12 1993-08-19 Kragler Peter Arzneimittel zur behandlung und/oder prophylaxe von stoerungen des folat-stoffwechsels
EP0572922A1 (fr) * 1992-06-05 1993-12-08 ASTA Medica Aktiengesellschaft Combinaisons synergiques comprenant de l'acide lipoique et des vitamines dans des médicaments
CN1129113A (zh) * 1995-01-20 1996-08-21 赵汝熹 爱滋病特效治疗剂

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2427824A (en) * 2002-05-29 2007-01-10 Insignion Holdings Ltd Treatment of proliferative or viral conditions
GB2392618B (en) * 2002-05-29 2007-02-21 Insignion Holdings Ltd Compositions for therapeutic use
EP1627663A3 (fr) * 2004-05-18 2006-03-15 Franco Deraco Utilisation d'une composition pharmaceutique pour le traitement de pathologies dérivées d'une infection par le virus de l'herpès, le virus de papillome, le virus de l'hépatite, la neuralgie virale, la dysplasie virale, les infections virales induites par une insuffisance immunitaire et la névrite virale
WO2007065314A1 (fr) * 2005-12-08 2007-06-14 Pficker Pharmaceuticals, Ltd. Composition pour le traitement d'une hepatopathie virale
WO2015070280A1 (fr) * 2013-11-14 2015-05-21 Newsouth Innovations Pty Limited Senescence et phénotype sécrétoire associé à une senescence
US11389469B2 (en) 2015-04-28 2022-07-19 Newsouth Innovations Pty Ltd Targeting NAD+ to treat chemotherapy and radiotherapy induced cognitive impairment, neuropathies and inactivity
FR3075037A1 (fr) * 2017-12-20 2019-06-21 Pierre Fabre Dermo-Cosmetique Association d'un retinoide et d'un extrait de silybum marianum (l.) gaertn
RU2794229C2 (ru) * 2017-12-20 2023-04-13 Пьер Фабр Дермо-Косметик КОМБИНАЦИЯ РЕТИНОИДА И ЭКСТРАКТА Silybum marianum (L.) Gaertn
US11690886B2 (en) 2017-12-20 2023-07-04 Pierre Fabre Dermo-Cosmetique Combination of a retinoid and an extract of Silybum marianum (L.) gaertn

Also Published As

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HK1046848A1 (en) 2003-01-30
AU2000231423A1 (en) 2001-09-12
CN1434710A (zh) 2003-08-06
CN1213747C (zh) 2005-08-10
HK1046848B (zh) 2006-04-13

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