WO2001038376A1 - Nouveau polypeptide, proteine humaine a doigt de zinc 46, et polynucleotide codant pour ce polypeptide - Google Patents

Nouveau polypeptide, proteine humaine a doigt de zinc 46, et polynucleotide codant pour ce polypeptide Download PDF

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Publication number
WO2001038376A1
WO2001038376A1 PCT/CN2000/000442 CN0000442W WO0138376A1 WO 2001038376 A1 WO2001038376 A1 WO 2001038376A1 CN 0000442 W CN0000442 W CN 0000442W WO 0138376 A1 WO0138376 A1 WO 0138376A1
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
zinc finger
polynucleotide
finger protein
human zinc
Prior art date
Application number
PCT/CN2000/000442
Other languages
English (en)
Chinese (zh)
Inventor
Yumin Mao
Yi Xie
Original Assignee
Bioroad Gene Development Ltd. Shanghai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioroad Gene Development Ltd. Shanghai filed Critical Bioroad Gene Development Ltd. Shanghai
Priority to AU15088/01A priority Critical patent/AU1508801A/en
Publication of WO2001038376A1 publication Critical patent/WO2001038376A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

L'invention concerne un nouveau polypeptide, une protéine humaine à doigt de zinc 46, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la protéine humaine à doigt de zinc 46.
PCT/CN2000/000442 1999-11-26 2000-11-20 Nouveau polypeptide, proteine humaine a doigt de zinc 46, et polynucleotide codant pour ce polypeptide WO2001038376A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU15088/01A AU1508801A (en) 1999-11-26 2000-11-20 A new polypeptide-zinc finger protein 46 and the polynucleotide encoding it

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN99124122.3 1999-11-26
CN99124122A CN1297915A (zh) 1999-11-26 1999-11-26 一种新的多肽——人锌指蛋白46和编码这种多肽的多核苷酸

Publications (1)

Publication Number Publication Date
WO2001038376A1 true WO2001038376A1 (fr) 2001-05-31

Family

ID=5283215

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2000/000442 WO2001038376A1 (fr) 1999-11-26 2000-11-20 Nouveau polypeptide, proteine humaine a doigt de zinc 46, et polynucleotide codant pour ce polypeptide

Country Status (3)

Country Link
CN (1) CN1297915A (fr)
AU (1) AU1508801A (fr)
WO (1) WO2001038376A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003599A1 (fr) * 1992-08-04 1994-02-17 Sagami Chemical Research Center ADNc HUMAIN ET PROTEINE POUR LAQUELLE CODE CET ADNc
WO1999021991A1 (fr) * 1997-10-29 1999-05-06 Shanghai Second Medical University Bmzf12: gene a doigt de zinc clone a partir de la moelle osseuse

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994003599A1 (fr) * 1992-08-04 1994-02-17 Sagami Chemical Research Center ADNc HUMAIN ET PROTEINE POUR LAQUELLE CODE CET ADNc
WO1999021991A1 (fr) * 1997-10-29 1999-05-06 Shanghai Second Medical University Bmzf12: gene a doigt de zinc clone a partir de la moelle osseuse

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CONSTANTINOU DELTAS C. ET AL.: "Complete coding sequence, exon/intron arrangement and chromosome location of ZNF45, a KRAB-domain-containing gene", CYTOGENET. CELL GENET., vol. 75, no. 4, 1996, pages 230 - 233 *
DERRY J.M. ET AL.: "Cloning and characterization of a novel zinc finger gene in Xp11.2", GENOMICS, vol. 30, no. 2, 1995, pages 361 - 365 *
THIESEN H.J. ET AL.: "Multiple genes encoding zinc finger domains are expressed in human T cells", NEW BIOL., vol. 2, no. 4, 1990, pages 363 - 374 *
TUNNACLIFFE A. ET AL.: "Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution", NUCLEIC ACIDS RES., vol. 21, no. 6, 1993, pages 1409 - 1417 *

Also Published As

Publication number Publication date
CN1297915A (zh) 2001-06-06
AU1508801A (en) 2001-06-04

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