WO2000078954A3 - Human transcriptional regulator proteins - Google Patents

Human transcriptional regulator proteins Download PDF

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Publication number
WO2000078954A3
WO2000078954A3 PCT/US2000/016766 US0016766W WO0078954A3 WO 2000078954 A3 WO2000078954 A3 WO 2000078954A3 US 0016766 W US0016766 W US 0016766W WO 0078954 A3 WO0078954 A3 WO 0078954A3
Authority
WO
WIPO (PCT)
Prior art keywords
transcriptional regulator
regulator proteins
txreg
human transcriptional
provides
Prior art date
Application number
PCT/US2000/016766
Other languages
French (fr)
Other versions
WO2000078954A2 (en
Inventor
Preeti Lal
Henry Yue
Y Tom Tang
Mariah R Baughn
Yalda Azimzai
Bao Tran
Original Assignee
Incyte Genomics Inc
Preeti Lal
Henry Yue
Y Tom Tang
Mariah R Baughn
Yalda Azimzai
Bao Tran
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Preeti Lal, Henry Yue, Y Tom Tang, Mariah R Baughn, Yalda Azimzai, Bao Tran filed Critical Incyte Genomics Inc
Priority to AU56230/00A priority Critical patent/AU5623000A/en
Priority to EP00941530A priority patent/EP1190050A2/en
Priority to JP2001505696A priority patent/JP2003517290A/en
Priority to CA002375414A priority patent/CA2375414A1/en
Publication of WO2000078954A2 publication Critical patent/WO2000078954A2/en
Publication of WO2000078954A3 publication Critical patent/WO2000078954A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides human transcriptional regulator proteins (TXREG) and polynucleotides which identify and encode TXREG. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of TXREG.
PCT/US2000/016766 1999-06-18 2000-06-15 Human transcriptional regulator proteins WO2000078954A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU56230/00A AU5623000A (en) 1999-06-18 2000-06-15 Human transcriptional regulator proteins
EP00941530A EP1190050A2 (en) 1999-06-18 2000-06-15 Human transcriptional regulator proteins
JP2001505696A JP2003517290A (en) 1999-06-18 2000-06-15 Human transcription regulatory protein
CA002375414A CA2375414A1 (en) 1999-06-18 2000-06-15 Human transcriptional regulator proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14010999P 1999-06-18 1999-06-18
US60/140,109 1999-06-18

Publications (2)

Publication Number Publication Date
WO2000078954A2 WO2000078954A2 (en) 2000-12-28
WO2000078954A3 true WO2000078954A3 (en) 2001-08-23

Family

ID=22489799

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/016766 WO2000078954A2 (en) 1999-06-18 2000-06-15 Human transcriptional regulator proteins

Country Status (5)

Country Link
EP (1) EP1190050A2 (en)
JP (1) JP2003517290A (en)
AU (1) AU5623000A (en)
CA (1) CA2375414A1 (en)
WO (1) WO2000078954A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1227148A4 (en) 1999-10-08 2003-04-16 Chugai Pharmaceutical Co Ltd Gene ys68 concerning early hematopoiesis
JP4112976B2 (en) * 2000-11-09 2008-07-02 株式会社Ｊｉｍｒｏ PCA2501 gene
US20040072997A1 (en) * 2000-12-20 2004-04-15 Alsobrook John P. Therapeutic polypeptides, nucleic acids encoding same, and methods of use
EP1425289A4 (en) * 2001-01-30 2004-10-13 Regeneron Pharma Novel nucleic acid and polypeptide molecules
JP3810731B2 (en) 2002-11-29 2006-08-16 独立行政法人科学技術振興機構 Novel adapter protein that binds to mammalian Toll-like receptor 3 and gene thereof
WO2004078112A2 (en) * 2003-03-07 2004-09-16 Asahi Kasei Pharma Corporation Apoptosis inducing gene
CN101061239B (en) * 2004-09-24 2011-08-17 肿瘤疗法科学股份有限公司 Method for diagnosing non-small cell lung cancers by tRNA-dihydrouridine synthase activity of URLC8

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726288A (en) * 1989-11-13 1998-03-10 Massachusetts Institute Of Technology Localization and characterization of the Wilms' tumor gene
US5861495A (en) * 1997-01-21 1999-01-19 Incyte Pharmaceuticals, Inc. Human zinc binding proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726288A (en) * 1989-11-13 1998-03-10 Massachusetts Institute Of Technology Localization and characterization of the Wilms' tumor gene
US5861495A (en) * 1997-01-21 1999-01-19 Incyte Pharmaceuticals, Inc. Human zinc binding proteins

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL EBI; 14 August 1996 (1996-08-14), MARRA ET AL.: "The WashU-HHMI Mouse EST project", XP002152509 *
DATABASE EMBL EBI; 17 March 1999 (1999-03-17), MARRA ET AL.: "The WashU-NCI mouse EST project", XP002152510 *
DATABASE EMBL EBI; 19 January 1997 (1997-01-19), HILLIER ET AL.: "Generation and analysis of 280,000 human expressed sequence tags", XP002152511 *
RAZDAN ET AL.: "Molecular cloning of a novel platelet protein showing homology to the angiotensin II receptor C-terminal domain", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 4, 26 January 1996 (1996-01-26), pages 2221 - 2224, XP002152508 *
REUTER S ET AL: "APM-1, A NOVEL HUMAN GENE, IDENTIFIED BY ABERRANT CO-TRANSCRIPTION WITH PAPILLOMAVIRUS ONCOGENES IN A CERVICAL CARCINOMA CELL LINE, ENCODES A BTB/POZ-ZINC FINGER PROTEIN WITH GROWTH INHIBITORY ACTIVITY", EMBO JOURNAL,GB,OXFORD UNIVERSITY PRESS, SURREY, vol. 17, no. 1, 1 January 1998 (1998-01-01), pages 215 - 222, XP000867721, ISSN: 0261-4189 *

Also Published As

Publication number Publication date
AU5623000A (en) 2001-01-09
EP1190050A2 (en) 2002-03-27
CA2375414A1 (en) 2000-12-28
JP2003517290A (en) 2003-05-27
WO2000078954A2 (en) 2000-12-28

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