WO1999061614A3 - Human socs proteins - Google Patents

Human socs proteins Download PDF

Info

Publication number
WO1999061614A3
WO1999061614A3 PCT/US1999/011497 US9911497W WO9961614A3 WO 1999061614 A3 WO1999061614 A3 WO 1999061614A3 US 9911497 W US9911497 W US 9911497W WO 9961614 A3 WO9961614 A3 WO 9961614A3
Authority
WO
WIPO (PCT)
Prior art keywords
hscop
socs proteins
human socs
provides
proteins
Prior art date
Application number
PCT/US1999/011497
Other languages
French (fr)
Other versions
WO1999061614A2 (en
Inventor
Preeti Lal
Jennifer L Hillman
Gina Gorgone
Neil C Corley
Chandra Patterson
Henry Yue
Y Tom Tang
Yalda Azimzai
Original Assignee
Incyte Pharma Inc
Preeti Lal
Jennifer L Hillman
Gina Gorgone
Neil C Corley
Chandra Patterson
Henry Yue
Y Tom Tang
Yalda Azimzai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Preeti Lal, Jennifer L Hillman, Gina Gorgone, Neil C Corley, Chandra Patterson, Henry Yue, Y Tom Tang, Yalda Azimzai filed Critical Incyte Pharma Inc
Priority to CA002329053A priority Critical patent/CA2329053A1/en
Priority to JP2000550998A priority patent/JP2002516101A/en
Priority to EP99925811A priority patent/EP1082426A2/en
Priority to AU42026/99A priority patent/AU4202699A/en
Publication of WO1999061614A2 publication Critical patent/WO1999061614A2/en
Publication of WO1999061614A3 publication Critical patent/WO1999061614A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides human SOCS proteins (HSCOP) and polynucleotides which identify and encode HSCOP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSCOP.
PCT/US1999/011497 1998-05-28 1999-05-25 Human socs proteins WO1999061614A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002329053A CA2329053A1 (en) 1998-05-28 1999-05-25 Human socs proteins
JP2000550998A JP2002516101A (en) 1998-05-28 1999-05-25 Human SOCS protein
EP99925811A EP1082426A2 (en) 1998-05-28 1999-05-25 Human socs proteins
AU42026/99A AU4202699A (en) 1998-05-28 1999-05-25 Human socs proteins

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8710498P 1998-05-28 1998-05-28
US60/087,104 1998-05-28
US21600698A 1998-12-17 1998-12-17
US09/216,006 1998-12-17

Publications (2)

Publication Number Publication Date
WO1999061614A2 WO1999061614A2 (en) 1999-12-02
WO1999061614A3 true WO1999061614A3 (en) 2000-03-02

Family

ID=26776595

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011497 WO1999061614A2 (en) 1998-05-28 1999-05-25 Human socs proteins

Country Status (5)

Country Link
EP (1) EP1082426A2 (en)
JP (1) JP2002516101A (en)
AU (1) AU4202699A (en)
CA (1) CA2329053A1 (en)
WO (1) WO1999061614A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020065223A1 (en) * 2000-06-16 2002-05-30 Glucksmann Maria Alexandra 33358, a novel human ankyrin family member and uses thereof
US20040086857A1 (en) * 2000-03-29 2004-05-06 Kyoko Takeuchi Proliferative glomerular nephritis-associated gene
DE10025521A1 (en) * 2000-05-23 2001-12-06 Boehringer Ingelheim Int Tumor-associated antigen B132
CN1331096A (en) * 2000-06-28 2002-01-16 上海博德基因开发有限公司 Polypeptide-cytokine signal inhibitor SOCS-5-29 and polynucleotide for coding it
US20040106784A1 (en) * 2000-12-14 2004-06-03 Parodi Luis A. Socs (suppressor of cytokine signaling)
US20060194275A1 (en) * 2001-04-13 2006-08-31 Incyte Corporation Transporter and ion channels
US7348139B1 (en) 2001-04-13 2008-03-25 The Johns Hopkins University School Of Medicine SOCS-1 gene methylation in cancer
AUPR556601A0 (en) * 2001-06-08 2001-07-12 Ludwig Institute For Cancer Research Therapeutic and diagnostic molecules - II
JP5896195B2 (en) * 2008-11-27 2016-03-30 国立研究開発法人医薬基盤・健康・栄養研究所 Anticancer agent containing SOCS activator as active ingredient
ATE525612T1 (en) 2009-07-02 2011-10-15 Hagn Leone Gmbh LED FLAT LAMP
JP5904649B2 (en) * 2014-12-24 2016-04-13 国立研究開発法人医薬基盤・健康・栄養研究所 Anticancer agent containing SOCS activator as active ingredient

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019734A1 (en) * 1991-05-03 1992-11-12 Yale University Binding domains in notch and delta proteins
WO1998020023A1 (en) * 1996-11-01 1998-05-14 The Walter And Eliza Hall Institute Of Medical Research Therapeutic and diagnostic agents capable of modulating cellular responsiveness to cytokines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019734A1 (en) * 1991-05-03 1992-11-12 Yale University Binding domains in notch and delta proteins
WO1998020023A1 (en) * 1996-11-01 1998-05-14 The Walter And Eliza Hall Institute Of Medical Research Therapeutic and diagnostic agents capable of modulating cellular responsiveness to cytokines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
D J HILTON ET AL: "Twenty proteins containing a C-terminal SOCS box form five structural classes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 95, 1 January 1998 (1998-01-01), pages 114 - 119, XP002085497, ISSN: 0027-8424 *
DATABASE EMEST16 EMBL, Heidelberg, Germany; 29 April 1997 (1997-04-29), HILLIER L ET AL.: "Homo sapiens cDNA clone 742641", XP002115960 *

Also Published As

Publication number Publication date
EP1082426A2 (en) 2001-03-14
JP2002516101A (en) 2002-06-04
AU4202699A (en) 1999-12-13
CA2329053A1 (en) 1999-12-02
WO1999061614A2 (en) 1999-12-02

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