WO2001005970A3 - Gtp-binding protein associated factors - Google Patents

Gtp-binding protein associated factors Download PDF

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Publication number
WO2001005970A3
WO2001005970A3 PCT/US2000/019698 US0019698W WO0105970A3 WO 2001005970 A3 WO2001005970 A3 WO 2001005970A3 US 0019698 W US0019698 W US 0019698W WO 0105970 A3 WO0105970 A3 WO 0105970A3
Authority
WO
WIPO (PCT)
Prior art keywords
gtp
binding protein
gbap
protein associated
associated factors
Prior art date
Application number
PCT/US2000/019698
Other languages
French (fr)
Other versions
WO2001005970A2 (en
Inventor
Henry Yue
Y Tom Tang
Olga Bandman
Jennifer L Hillman
Preeti Lal
Janice Au-Young
Roopa Reddy
Junming Yang
Mariah R Baughn
Dyung Aina M Lu
Yalda Azimzai
Chandra Patterson
Original Assignee
Incyte Genomics Inc
Henry Yue
Y Tom Tang
Olga Bandman
Jennifer L Hillman
Preeti Lal
Au Young Janice
Roopa Reddy
Junming Yang
Mariah R Baughn
Dyung Aina M Lu
Yalda Azimzai
Chandra Patterson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Henry Yue, Y Tom Tang, Olga Bandman, Jennifer L Hillman, Preeti Lal, Au Young Janice, Roopa Reddy, Junming Yang, Mariah R Baughn, Dyung Aina M Lu, Yalda Azimzai, Chandra Patterson filed Critical Incyte Genomics Inc
Priority to CA002379968A priority Critical patent/CA2379968A1/en
Priority to EP00948792A priority patent/EP1196575A2/en
Priority to JP2001511183A priority patent/JP2003505029A/en
Priority to AU62237/00A priority patent/AU6223700A/en
Publication of WO2001005970A2 publication Critical patent/WO2001005970A2/en
Publication of WO2001005970A3 publication Critical patent/WO2001005970A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides human GTP-binding associated proteins (GBAP) and polynucleotides which identify and encode GBAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of GBAP.
PCT/US2000/019698 1999-07-19 2000-07-19 Gtp-binding protein associated factors WO2001005970A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002379968A CA2379968A1 (en) 1999-07-19 2000-07-19 Gtp-binding protein associated factors
EP00948792A EP1196575A2 (en) 1999-07-19 2000-07-19 Gtp-binding protein associated factors
JP2001511183A JP2003505029A (en) 1999-07-19 2000-07-19 GTP binding protein
AU62237/00A AU6223700A (en) 1999-07-19 2000-07-19 Gtp-binding associated proteins

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US14459599P 1999-07-19 1999-07-19
US60/144,595 1999-07-19
US15046099P 1999-08-23 1999-08-23
US60/150,460 1999-08-23
US15984999P 1999-10-15 1999-10-15
US60/159,849 1999-10-15

Publications (2)

Publication Number Publication Date
WO2001005970A2 WO2001005970A2 (en) 2001-01-25
WO2001005970A3 true WO2001005970A3 (en) 2001-04-26

Family

ID=27386130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/019698 WO2001005970A2 (en) 1999-07-19 2000-07-19 Gtp-binding protein associated factors

Country Status (5)

Country Link
EP (1) EP1196575A2 (en)
JP (1) JP2003505029A (en)
AU (1) AU6223700A (en)
CA (1) CA2379968A1 (en)
WO (1) WO2001005970A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU779839B2 (en) * 1999-11-01 2005-02-17 Nalan Utku Novel genes TZap7/A, TZap7/B and TZap7 involved in T cell activation and uses thereof
EP1248839B1 (en) 2000-01-21 2010-04-07 Polymun Scientific Immunbiologische Forschung GmbH Tumor and senescence marker
US6509155B1 (en) * 2000-02-18 2003-01-21 Incyte Genomics, Inc. Nucleic acids encoding GTPase activating proteins
US6897020B2 (en) 2000-03-20 2005-05-24 Newlink Genetics Inc. Methods and compositions for elucidating relative protein expression levels in cells
US7611892B2 (en) 2000-03-24 2009-11-03 President And Fellows Of Harvard College Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US7189565B2 (en) 2001-03-23 2007-03-13 Fahri Saatcioglu Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
AU4941101A (en) * 2000-03-24 2001-10-08 Fahri Saatcioglu Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods
JP2003532415A (en) * 2000-05-05 2003-11-05 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング Novel Ras guanine-nucleotide exchange factor 1 (NRG1)
ATE397060T1 (en) * 2000-05-30 2008-06-15 Moelling Karin Inst Fuer Med V NUCLEIC ACID MOLECULES ENCODING A PROTEIN WHICH INTERACTS WITH A SER/THR AKT KINASE
US20020146800A1 (en) * 2000-08-30 2002-10-10 Curtis Rory A.J. 48921, a novel human GTP releasing factor and uses therefor
EP1201680A3 (en) * 2000-10-24 2003-05-14 Urogene Société anonyme Tumor suppressor polypeptide issued from CHC1-L (chromosome condensation 1-like)
EP1231216A3 (en) * 2001-01-30 2004-03-17 Aeomica, Inc. Human gtp-rho binding protein 2
EP1575984A4 (en) 2001-02-16 2006-09-06 Bristol Myers Squibb Co Identification and cloning of a novel human gene, ret16, involved in the intracellular signaling cascade
US20020142431A1 (en) * 2001-03-27 2002-10-03 Merkulov Gennady V. Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
WO2008111520A1 (en) * 2007-03-09 2008-09-18 Nagasaki University Gene related to life extension and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (en) * 1998-05-14 1999-11-18 Chiron Corporation Human genes and gene expression products v

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058675A2 (en) * 1998-05-14 1999-11-18 Chiron Corporation Human genes and gene expression products v

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CLAPHAM, D.E. ET AL.: "New roles for G-protein beta-gamma-dimers in transmembrane signalling.", NATURE, vol. 365, 30 September 1993 (1993-09-30), pages 403 - 6, XP002148967 *
DATABASE EMBL - EMEST_HUM13 25 May 1997 (1997-05-25), HILLIER, L. ET AL.: "zw60f01.r1 Soares_total_fetus_Nb2HF8_9w Homo sapiens cDNA clone IMAGE:774457 5' similar to SW:YSXC_BACSU P38424 HYPOTHETICAL 22.0 KD PROTEIN IN LON-HEMA INTERGENIC REGION ;, mRNA sequence.", XP002148939 *
DATABASE EMBL - EMEST_ROD2 8 September 1998 (1998-09-08), MARRA, M. ET AL.: "uc46f10.r1 Soares mouse mammary gland NMLMG Mus musculus cDNA clone IMAGE:1401067 5' similar to SW:Y335_MYCGE P47577 HYPOTHETICAL GTP-BINDING PROTEIN MG335. ;, mRNA sequence.", XP002148940 *
DATABASE EMBL - EMHUM2 1 February 2000 (2000-02-01), YE, M. ET AL.: "Homo sapiens HSPC135 mRNA, complete cds.", XP002148941 *
DATABASE EMEST_HUM1 4 December 1997 (1997-12-04), HILLIER, L. ET AL.: "zj49c09.s1 Soares fetal liver spleen 1NFLS S1 Homo sapiens cDNA clone 453616 3' similar to TR:G1230663 G1230663 SIMILAR TO E. COLI HYPOTHETICAL 22.1 KD PROTEIN IN POLA 3' REGION.", XP002148938 *

Also Published As

Publication number Publication date
CA2379968A1 (en) 2001-01-25
AU6223700A (en) 2001-02-05
WO2001005970A2 (en) 2001-01-25
EP1196575A2 (en) 2002-04-17
JP2003505029A (en) 2003-02-12

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