WO2000072181A2 - Systeme de gestion integree de l'information medicale - Google Patents

Systeme de gestion integree de l'information medicale Download PDF

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Publication number
WO2000072181A2
WO2000072181A2 PCT/US2000/013983 US0013983W WO0072181A2 WO 2000072181 A2 WO2000072181 A2 WO 2000072181A2 US 0013983 W US0013983 W US 0013983W WO 0072181 A2 WO0072181 A2 WO 0072181A2
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WO
WIPO (PCT)
Prior art keywords
data
patient
reports
central server
remote access
Prior art date
Application number
PCT/US2000/013983
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English (en)
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WO2000072181A9 (fr
WO2000072181A3 (fr
Inventor
Kevin C. Wells
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Minimed Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minimed Inc. filed Critical Minimed Inc.
Priority to JP2000620504A priority Critical patent/JP2003500744A/ja
Priority to EP00937654A priority patent/EP1194864A2/fr
Priority to AU52797/00A priority patent/AU5279700A/en
Priority to CA002372656A priority patent/CA2372656A1/fr
Publication of WO2000072181A2 publication Critical patent/WO2000072181A2/fr
Publication of WO2000072181A3 publication Critical patent/WO2000072181A3/fr
Publication of WO2000072181A9 publication Critical patent/WO2000072181A9/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Definitions

  • This invention relates to an integrated medical information management system, and in particular embodiments, to an integrated system that utilizes remote communication stations, facsimile, E-mail and the internet to retrieve patient data and to provide reports to a patient, healthcare provider, HMO and/or insurer to manage diabetes.
  • Type I diabetics is growing at 3% or more per year.
  • growing numbers of insulin using Type II diabetics are using external insulin infusion pumps. Physicians have recognized that continuous infusion provides greater control of a diabetic's condition, and are increasingly prescribing it for patients. Greater control reduces the complications associated with the disease of diabetes.
  • data from the treatment of diabetes is stored in logbook or is stored in the memory of a treatment or monitoring device. This information is then transferred by hand or downloaded to a local computer.
  • the data is not easily transferred to the healthcare provider or specialist.
  • the data must be brought to those who need to review it or it is transferred over a modem.
  • this normally requires a visit to the healthcare provider and the data must be reviewed at that time. It is generally not feasible for the data to be transmitted to the healthcare provider on a regular basis for routine monitoring and analysis, since the healthcare provider must analyze and interpret the data using their own time and computer.
  • an integrated medical information management system includes at least one on-line central server and at least one remote access terminal.
  • the at least one on-line central server contains patient related data for at least one patient.
  • the at least one remote access terminal is used to interactively access the patient related data for the at least one patient from the on-line central server to generate interactive reports based on the patient related data for the at least one patient on the at least one remote access terminal.
  • the at least one on-line central server is connected to the at least one remote access terminal through an internet connection and the at least one remote access terminal utilizes an internet web browser to interactively access the at least one on-line central server.
  • Preferred embodiments use patient related data that is related to the disease of diabetes.
  • an integrated medical information management system includes at least one on-line central server, at least one medical device, at least one data receiving device and at least one remote access device.
  • the at least one on-line central server contains patient related data for at least one patient.
  • the at least one medical device is related to treatment of a disease of a patient, and includes memory to store data about the use of the device by the patient.
  • the at least one data receiving device receives the data from the at least one medical device, and uploads the data to the at least one on-line central server as patient related data.
  • the at least one remote access device is for receiving patient related data from the at least one on-line central server.
  • the at least one least one remote access device is a remote access terminal used to interactively access the patient related data for the at least one patient to generate interactive reports based on the patient related data for the at least one patient on the at least one remote access terminal.
  • the at least one on-line central server is connected to the at least one remote access terminal through an internet or intranet connection and utilizes an internet web browser to interactively access the at least one on-line central server.
  • the at least one remote access device is a facsimile machine. Additional embodiments further include a communication station interface between the at least one medical device and the at least one data receiving device.
  • Preferred medical devices include infusion devices, glucose monitors and/or glucose meters.
  • the patient related data may be medication infusion data, glucose monitor data and/or glucose meter data.
  • the at least one remote access device is used to receive E-mail reports.
  • the at least one data receiving device is capable of receiving requests for reports from the at least one on-line central server.
  • the at least one data receiving device is capable of receiving requests for ordering supplies, and/or for scheduling appointments.
  • the at least one remote access device further includes an ability to order supplies through the at least one on-line central server based on the uploaded data from the at least one medical device.
  • the system further includes a data bus that allows data from different types of the at least one medical device to be captured, stored, manipulated and reported on independent of the specific type of device connected to the data bus.
  • the data bus utilizes data elements and/or collections of data elements to process data.
  • the at least one on-line central server automatically generates reports at predetermined times.
  • the reports may be sent out by mail, E- mail, internet, intranet, dedicated lines, or the like. Further embodiments can create group reports of more than the at least one patient are generated. In addition, reports may be sent to managed care providers (HMOs).
  • HMOs managed care providers
  • Embodiments may also include the ability to schedule appointments, to bill clients, and/or to process insurance claims.
  • the data is captured automatically by a device and/or captured by manual entry of data by an individual.
  • the data is glucose consumption data, exercise data, caloric burn data, medication consumption data from sources independent of infusion data, lab test data, or the like.
  • the patient can review the data, and may also be able to analyze it and generate reports.
  • the data is used to generate reports.
  • the data is used to produce reports that include components selected from the group of graphical elements, textual elements, numerical elements and tabular elements that represent the data.
  • the data may be used to produce reports on the use of medical supplies and/or produce reports that provide conclusions regarding the use of medical supplies.
  • the data is used to produce reports that highlight problems or issues and/or produce reports that highlight or recommend areas for adjustments in regimes.
  • the embodiments may also utilize expert logic.
  • the system generates reports independent of the type of at least one medical device, at least one data receiving device or at least one remote access device utilized by the system.
  • the system includes the capability to combine some to all of the data on the at least one online central server into a single data storage and reporting mechanism.
  • the system includes the capability to combine or juxtapose some to all of the data on the at least one on-line central server into a single report.
  • the system includes the capability to form conclusions and recommend actions based on some to all of the data on the at least one on-line central server by correlating various portions of data in ways not otherwise be possible when referencing the various portions of data separately.
  • a data storage and reporting system includes a data bus that allows data collected from various different medical devices, which use various different formats and types of data.
  • the data bus allows the data to be collected and reported on in a manner independent of a health care provider, a patient, or a system being required to be aware of the difference between the different formats and types of data.
  • the data bus utilizes data elements and/or collections of data to process data. Also, the system that transforms the various data formats from the various different medical devices into a single consistent representation for storage.
  • the system allows mixed data from the different medical devices to be stored into a database in a single operation.
  • the system may also transform the various data formats from the various different medical devices into a single consistent representation for reporting.
  • the system allows data from the different medical devices to be stored and presented in a consistent style of presentation. Also, the system may also allow data from the different medical devices to be stored, manipulated, and reported on independent of developing program code to specifically handle each different medical device. In further embodiments, the system allows simultaneous calculations on data combined from different medical devices independent of the mix of different medical data devices from which the data originated. Also, the system may allow calculations on data combined from the different medical devices to be organized as different groups to be performed in a single operation. For instance, the system computes an average blood glucose value as measured by several different blood glucose meters, for each day in a series of days with a single operation.
  • the system allows data from new different medical devices to be combined into the system with minimal of additional programming.
  • the system may allow data from different medical devices with similar purposes having data in various different data formats and types to be combined on a single, uniform report or graph. (For example, a single patient may use two different blood glucose meters from two different companies simultaneously. The system would allow the information from these meters to be combined (even interspersed) on a single report).
  • FIG. 1 is a system architecture drawing of the integrated medical information management system in accordance with an embodiment of the present invention.
  • Fig. 2 is a system architecture drawing of a prototype integrated medical information management system in accordance with another embodiment of the present invention.
  • Figs. 3-5 are block diagrams and drawings further illustrating the reporting architecture used by the integrated medical information management system shown in Fig. 1.
  • Fig. 6 is a block diagram and drawing showing how data is uploaded from infusion devices, monitors and meters to a PC, laptop or the internet through a user interface in accordance with an embodiment of the present invention.
  • Fig. 7 is a block diagram illustrating the structure of the data bus utilized in the integrated medical information management system.
  • Fig. 8 is a diagram of examples of data management applications for specific market segments.
  • Fig. 9 is a screen view of an interactive report generating screen used by a healthcare provider over the internet to obtain detailed reports.
  • Fig. 10 is a three day report generated in response to the report requested from the screen in Fig. 9.
  • Fig. 1 1 is an expanded view of the first day shown in Fig. 10.
  • Fig. 12 is an expanded view of the second day shown in Fig. 10.
  • Fig. 13 is an expanded view of the third day shown in Fig. 10.
  • Fig. 14 is a comparison view of the three days shown in Fig. 10 overlaid on the same graph to show how each day compared to the others.
  • Fig. 15 is a two week summary chart report, with glucose monitor data, modal day, blood glucose summary statistics and insulin usage reports.
  • the invention is embodied in an integrated medical information management system for assisting patients, healthcare providers, Managed care or Health Maintenance
  • HMOs Health Organizations
  • insurers in managing the information available from medical treatment to better treat the symptoms and effects of the disease.
  • Preferred embodiments are directed to the management of diabetes information and utilize infusion devices and glucose monitors and/or meters that have the ability to store information about the infusion of fluids and the measured glucose levels.
  • patients, or local healthcare providers download stored data from the devices using a Communication-Station I or II, modem, or the like, to a PC, laptop, or data processor, and then to a central server either via a modem, E-mail or internet connection. The stored data is then analyzed and preliminary reports are provided to the patient's physician or other healthcare provider by facsimile, E-mail or internet.
  • the physician can also access the data on the server through an internet (or modem) connection to generate custom reports to highlight or further analyze the data regarding the patient.
  • healthcare providers, HMOs and insurers can access the stored data (generally in a database) to obtain general patient statistics and to receive warnings about individual patients that appear to be outside of the normal disease state condition, and which may require attention from a healthcare provider.
  • the data may also be downloaded to the healthcare provider for additional detailed analysis on a PC, laptop, or processor that is locally based with the healthcare provider.
  • Preferred embodiments are directed to managing the disease of diabetes. However, alternative embodiments may be directed to other diseases, such as asthma, heart disease, AIDS, cancer, or the like.
  • the integrated medical information management system provides centralized storage and processing for patients, healthcare providers, HMOs and providers.
  • the patient uses infusion devices, such as an infusion pump, or the like, to administer medication.
  • the infusion device includes memory to store the infusion history data, as well as any alarms or other relevant data needed for proper infusion.
  • the patient will also monitor their condition using a glucose meter with individual finger pricks and/or a glucose monitor for continuous (or near continuous) monitoring of the patients condition.
  • These devices also store the data and relevant information about the patient ' s condition.
  • the patient will place the infusion device, the meter and/or monitor into a Communication-Station I or II, or other suitable device, to download data to a local PC, laptop computer, data processor, or the like.
  • different intervals such as other day multiples, weeks, or months may be used.
  • the infusion device, monitor and/or meter may include the ability to transmit the data directly to the PC, laptop computer, data processor, or the like. After downloading the data, the patient may view and work with the data for their own review.
  • the integrated medical information management system will generally work in conjunction with the Communication Station ("Corn-Station " ), which is described in U.S. Patent Application Serial No.
  • the data will be uploaded to a central server, either by modem connection or through the Internet.
  • the data may be uploaded directly through the Communication-Station.
  • the data may be uploaded to the central server through a satellite link, cellular telephone link, E-mail, or the like.
  • the uploaded data may be interpreted and used to automatically order supplies and materials to be sent to the patient to maintain the patients condition.
  • a report will be periodically generated and sent to the healthcare provider.
  • the report is facsimiled.
  • alternative embodiments may E-mail the report and/or send downloaded raw data for the healthcare provider to review and study.
  • the healthcare provider can order through E-mail and/or go on-line to request a custom report for particular periods, parameters, comparisons, or the like.
  • the connection may be through the internet, modem or other suitable data transfer method, and the data for each of the healthcare provider's patients can be accessed and then reported on.
  • the healthcare provider is able to quickly interact with the data and obtain desired reports.
  • the physician may also instruct the central server to monitor particular aspects or parameters of the patient's data and to trigger an alert or notification upon the occurrence of a particular event or condition.
  • This allows the healthcare provider to learn about various disease conditions on a more frequent basis.
  • the healthcare provider can obtain detailed data that can be reviewed prior to the patient coming in for a visit, which tends to make the visit much more productive and useful to both the patient and the healthcare provider.
  • HMOs and/or insurers can also benefit from the central database, since they can monitor statistical information regarding all patients on the central server, and can monitor their patient subscribers as a group to determine key aspects of the disease that affect their subscribers. It could also provide them with alerts when particular patients (or classes of patients) appear to be having difficulties so that proactive treatment can be ordered.
  • patients will be identified by the serial numbers of their devices. Some form of authentication security will be required to ensure that the identity of a particular device/patient cannot be confused or obtained without authorization. Any data transmitted over a public network or the internet may be encrypted for added security. In addition, all internet transactions will be encrypted, and internet based access will be protected by username/password login.
  • Fig. 1 illustrates the system architecture of an integrated medical information management system 10 in accordance with an embodiment of the present invention.
  • Preferred embodiments utilize an analysis server 12 that accesses a patient database 14 used to store and analyze data as described in more detail below.
  • Patient data in the database 14 is generally stored for specified periods of time (such as 3 months, a year, or the like) and older data will then be stored in off-line media.
  • the analysis server 12 is also connected to various external data sources and processors through data modems 16, fax modems 18, and/or a web server 20 that connects to the internet 22.
  • the various servers may be combined or formed as a plurality of different interconnected servers with the configuration being dependent on the system architecture, the number of anticipated users, the type of connections used, the amount of data handled, or the like.
  • a patient home computer 24 can connect to the web server 20 through the internet 22.
  • the patient home computer 24 may connect to the analysis server 12 through the data modems 16 (using dedicated dial-in lines or local access numbers connected to third party networks for access), a direct wire connection, or the like.
  • a Dr.'s office computer 26 is connected to the analysis server 12 through the data modems 16.
  • the Dr.'s office computer 26 may be connected to the web server 20 through the internet 22. Although only shown for the Dr.'s office computer 26, the following may also be connected to the patient home computer 24.
  • the Dr.'s office computer 26 is connected to a communication station 28 that can download data from a glucose monitor 30 (such as those produced by MiniMed Inc. for continuous or near continuous glucose measurements) and/or an infusion device 32 (such as the MiniMed 407C infusion pump, 507C infusion pump, 508 infusion pump, or the like).
  • a glucose monitor 30 such as those produced by MiniMed Inc. for continuous or near continuous glucose measurements
  • an infusion device 32 such as the MiniMed 407C infusion pump, 507C infusion pump, 508 infusion pump, or the like.
  • the Dr.'s office computer 26 may be omitted and the glucose monitor 30 and infusion device 32 are connected to a communication station II 34, which includes additional capabilities such as a display, additional control buttons, RF communication capabilities and built in modems.
  • a detailed description of a communication station and communication station II is disclosed in U.S. Patent No. 5,376,070 and U.S. Patent Application Serial No.
  • Dr.'s office computer 26 may also be capable of being connected to other devices, such as glucose meters 36 (such as the AccuChek by Roche, the Lifescan by Johnson & Johnson, the Medisense meter by Abbott, the Elite by Bayer, or the like) through a direct wire, IR, RF connection, or the like.
  • glucose meters 36 such as the AccuChek by Roche, the Lifescan by Johnson & Johnson, the Medisense meter by Abbott, the Elite by Bayer, or the like
  • the glucose meters 36 may be connected through the communication station 28 or communication station II 34 in either a pass-through mode or using the stations 28 or 34 as an interface.
  • the receiving device for reports and data, and the remote access device for providing and receiving data may be the same device.
  • the integrated medical information management system 10 also may include managed care organization computers (HMO) 38 that are connected to the web server 20 through the internet 22 or, alternatively, to the analysis server 12 through the data modems 16.
  • HMO managed care organization computers
  • FIG. 2 is a system architecture drawing of an integrated medical information management system 100 in accordance with another embodiment of the present invention.
  • the integrated medical information management system 100 is similar to the integrated medical information management system 10, but is designed to work with intranet 102 connections rather than the internet connections. This system is suitable for management within an organization with satellite offices. This system may also provide greater security, where this is a concern, since the public internet is not used for data transmissions.
  • Preferred embodiments utilize an analysis server 104 that accesses a patient data base 106.
  • the data base 106 is used to store and analyze data as described in more detail below.
  • the analysis server 104 is also connected to various external data sources and processors through data modems 108, fax modems 110, and/or connects to the intranet 102.
  • a Dr.'s office computer 1 12 (or alternatively, a patient home computer) is connected to the analysis server 104 through the data modems 108.
  • the Dr.'s office computer 112 may be connected through the intranet 102.
  • the Dr.'s office computer 112 is connected to a communication station 1 14 that can download data from a glucose monitor 1 16 (such as those produced by MiniMed Inc. for continuous or near continuous glucose measurements) and/or an infusion device 118 (such as the MiniMed 407C infusion pump, 507C infusion pump, 508 infusion pump, or the like).
  • a glucose monitor 1 16 such as those produced by MiniMed Inc. for continuous or near continuous glucose measurements
  • an infusion device 118 such as the MiniMed 407C infusion pump, 507C infusion pump, 508 infusion pump, or the like.
  • the Dr.'s office computer 112 is also capable of being connected to other devices, such as glucose meters 120 (such as the AccuChek by Roche, the Lifescan by Johnson & Johnson, the Medisense meter by Abbott, the Elite by Bayer, or the like) through a direct wire, IR, RF connection, or the like.
  • glucose meters 120 such as the AccuChek by Roche, the Lifescan by Johnson & Johnson, the Medisense meter by Abbott, the Elite by Bayer, or the like
  • the glucose meters 120 may be connected through the communication station 1 14 in either a pass- through mode or using the station 1 14 as an interface.
  • the integrated medical information management system 100 also may include managed care organization computers (HMO) 122 that are connected through the intranet 102 or, alternatively, to the analysis server 104 through the data modems 108.
  • HMO managed care organization computers
  • Other data transmitting/receiving appliances 124 such as fax machines, scanners (not shown), or the like, may be connected to the analysis server 104 through the fax modems 1 10 to send and receive data for analysis.
  • Alternative embodiments may utilize software on computers to communicate with the analysis server 104 by other methods, such as IR data links, satellite data links, cellular data links, or the like.
  • Figs. 3-5 are block diagrams that illustrate the reporting architecture 200 used by the integrated medical information management systems shown in Figs. 1 and 2.
  • the reporting architecture 200 receives data through a receiving program 202 that manages communication with the communication-stations I or II, computers, medical devices, or the like.
  • the receiving program 202 stores the data in an intermediate format (which may be a disk file 206).
  • the data is then processed by a loading program 204, which is responsible for storing the information to the system database 212.
  • the loading program 204 uses the same data bus 208 (discussed in more detail below) for manipulating and storing data, as is used by the rest of the reporting architecture and applications.
  • This data bus 208 stores and retrieves data from the database using a database access framework 210 that includes a database object model 214 and a database interface 216.
  • the database access framework 210 and/or data bus 208 support additional administrative and customer service applications 218, including, but are not limited to, client and physician account establishment, customer service support, client billing, or the like.
  • Reporting applications 220 are used to generate various reports for use by the health care provider, patient, HMO, administrator, or the like.
  • the reporting applications 220 include a report scheduler 222 to schedule when reports are to be generated and sent out.
  • the reporting applications 220 also include report specifier logic 224 that specifies the logic and parameters used to generate by means of templates.
  • a report layout module 226 and report imaging module 228 are used to generate the actual the reports.
  • a charting module 230 and chart imaging module 232 are used to generate graphs used in a report.
  • reports are generated in multiple formats or combinations of formats including HTML, GIF, Encapsulated PostScript, PostScript, PDF and TIFF. In alternative embodiments, other formats such as JPEG, MPEG, or the like, may be used.
  • the reporting applications 220 also include an exception and expert logic module 234 to identify and communicate abnormal or unusual conditions based on the report data, and to make recommendations accordingly.
  • the output of the reporting applications 220 may be sent to the report delivery queues 236 for delivery by fax or E-mail.
  • the fax delivery mechanism 238 has faxing software and image generation software to deliver reports and charts via facsimile transmission to various receiving device.
  • the E-mail delivery mechanism 240 sends out reports via E-mail, such as text messages, attached files, embedded graphics, a combination of the preceding, or the like.
  • reports may be generated in HTML section 242 and published on a protected web site for viewing with a web browser.
  • a disk file 244 may be used to manage the report delivery queues and the HTML web-based generation of reports.
  • the reports may be printed out and then sent out by mail, Federal Express, UPS, or the like.
  • requests for reports may be received by mail, E-mail, telephone requests, telephone requests to the server, or the like.
  • Fig. 6 is a block diagram and drawing showing an application 300 for collecting data directly from medical devices including infusion devices 302, monitors 304, meters 306 and 308, and other medical devices 310 and uploading the data to a central server through a PC (such as 24 and 26 described above).
  • This application 300 consists of a user interface that utilizes a data bus 312 (described below) to communicate to a device/data manager 314.
  • the device/data manager 314 uses a plug in software architecture to communicate with the various medical devices. These plug-in modules may communicate directly with a serial port interface 316, or may use a library module 318 and/or 320 to communicate with the medical devices directly.
  • the serial port interface 316 is connectable to a communication station 322 (as described above) to connect the infusion devices 302 and/or the monitors 304, and/or meter devices 306 that utilize a pass-through in the communication station 322. In other embodiments, the serial port interface 316 is connectable to meters 306 that have the capability to directly connect to a serial data port.
  • the application 300 includes a file transfer module 324 for transferring data files through a modem 326.
  • patient A uses a blood glucose meter manufactured by company 1.
  • Patient B uses a blood glucose meter manufactured by company 2.
  • Both patients see physician C who is able to view a report for each patient without having to be aware of the differences between the blood glucose meters from companies 1 and 2. Therefore, embodiments of the system allow data from devices with similar purposes but different data formats and types to be combined on a single, uniform report. For example, a single patient may use two different blood glucose meters from two different companies simultaneously. The system would allow the data from these meters to be combined (even interspersed) on a single report. The same capability would apply to other medical devices, such as infusion devices, glucose monitors, or the like.
  • Fig. 8 is a diagram of examples of data management applications for specific market segments.
  • Figs. 9-15 illustrate exemplary views of reports and screens that may be generated by the integrated medical information management system. Generally, all of the screens shown in Figs. 9-15 are part of a single report; however, other embodiments may provide each screen separately, omit some or add additional screens, as an individual report.
  • Fig. 9 is a screen view of an interactive report generating screen used by a healthcare provider over the internet to obtain detailed reports.
  • Fig. 10 is a three day report generated in response to the report requested from the screen in Fig. 9.
  • Fig. 11 is an expanded view of the first day shown in Fig. 10.
  • Fig. 12 is an expanded view of the second day shown in Fig. 10.
  • Fig. 13 is an expanded view of the third day shown in Fig. 10.
  • Fig. 9 is a screen view of an interactive report generating screen used by a healthcare provider over the internet to obtain detailed reports.
  • Fig. 10 is a three day report generated in response to the report requested from the screen in Fig. 9.
  • Fig. 14 is a comparison view of the three days shown in Fig. 10 overlaid on the same graph to show how each day compared to the other days.
  • Fig. 15 is a two week summary chart report, with glucose monitor data, modal day, blood glucose summary statistics and insulin usage reports.
  • Other reports may be prepared and utilized by the integrated medical information management system, such as those disclosed and described in U.S. Patent Application Serial No. 09/409,014 filed September 29, 1999 and entitled "Communication Station and Software for Interfacing with an Infusion Pump, Analyte Monitor, Analyte Meter, or the like (published as WO 00/18449 on April 6, 2000), which is herein incorporated by reference. For instance, data from a device sensing a patient's physiological condition can be combined with data concerning medication usage.
  • the system then generates reports that juxtapose, in either graphical or textual format, the physiological and medication delivery data, glucose levels, carbohydrate consumption, or the like.
  • the system may also incorporate expert system logic for generating reports or identifying patients with problems to aid the health care provider in identifying unusual conditions or behavior based on the availability of both the physiological sensing data and the medication data in the same report.
  • the reporting architecture will operate generally by extracting information from the device data stored in the database based on specified criteria, performing calculations, creating charts (i.e. graphs, pie, bar or column charts, hybrids, or the like), and generating reports.
  • the basic report is generally one to several pages and includes graphical and tabular display of data, summary statistics, and exceptions.
  • the reports may include recommendations, compliance ratings, or the like.
  • the system will provide a flexible reporting structure which will allow new reports to be created relatively easily, will use configurable rule based logic for drawing conclusions and making recommendations, and will allow for smarter devices with increased memory capacity.
  • reports will consist of a set of components laid-out as blocks on a page.
  • the reporting system will use report templates to specify the layout of the reports.
  • Report components will generally consist of charts, tables, or text blocks. Elements may be mixed within a report component by using sub-components. This will allow reports to be hierarchical in design and will enable multiple reports to reuse a single component. Report components may mix data from different devices or types of devices.
  • the report layout mechanism will support text flow, line breaks, or the like. Text components may use a variety of fonts, sizes, and styles. (HTML based reports created for viewing on the internet will have some limitations in this area due to the nature of Internet browsers.)
  • the charting system will create charts in a variety of formats including bar and stacked bar, line, scatter, and area charts, and any combination of these.
  • the charting system will support flexible chart axis configuration including multiple axes for overlaid data. Most charts will use some form of date or time scale for the X-axis, and this scale may range from hours to years. In other embodiments, the charting system will support color charts where appropriate. Chart components may be generated as images using a document format separate from the report template language.
  • the integrated medical information management system will deliver reports under several selectable scenarios/conditions: prior to a care provider appointment; regularly (such as monthly or quarterly (potentially also to Managed care (HMOs)); when a health risk exception is detected (e.g. prolonged high or low blood sugar, or the like).
  • HMOs Managed care
  • the system will provide a 2-3 page report that will be faxed to the care provider's office. In this embodiment, no computer will be required either for the patient or care provider.
  • Further embodiments provide reports on demand to support diagnosis of control problems, maintaining control during illness, or the like. Still other embodiments will provide reports on a daily basis during initiation of pump therapy; each time data is uploaded to the integrated medical information management system, or the like.
  • the user of the integrated medical information management system uses the system to obtain treatment options by internet, E- mail, facsimile, or the like.
  • the system may also provide patient and physician education via interactive tutorials on the internet and proactive notifications with tips and education guidance by E-mail, facsimile, or the like. These can include disease state management and patient population risk management.
  • the integrated medical information management system may provide online product support for products ordered or used by users of the integrated medical information management system, such as frequently asked questions, instruction manuals, training aids (including interactive and non-interactive aids), programming tips, user suggestions, or the like. Still further embodiments may provide access to disease specific online patient community groups including posting, reading and replying to messages.
  • HMO Managed Care
  • HMO Managed Care
  • Preferred embodiments of the present invention use the integrated medical information management system to provide a more complete patient record; for automated collection and analysis of the patient record; for more accurate and immediate evaluation of patient health and compliance with a health care regimen; for more frequent interaction with the care provider; for providing information rather than data that is more summarized than the raw data, such as graphically versus tabular, or the like.
  • Other embodiments provide additional data collection based on automated patient surveys to support both direct patient care and medical and market research, such as by online surveys, market research, or the like.
  • Still further embodiments provide home monitoring services to provide alarms and call for assistance should unusual or pre-selected conditions be determined by the devices used by the user.
  • Additional embodiments may include a carbohydrate counter and meal planner to assist the user in evaluating the amount of carbohydrates to consume and the effects on insulin delivery requirements.
  • the integrated medical information management system will use one ore more servers to connect to the internet and/or to the intranet to produce a web site.
  • the web site of the integrated medical information management system will integrate the services and allow access to the services under a single login with simple, intuitive navigation.
  • the users can enter additional data such as meals and exercise; configure reports; produce ad hoc reports as web pages as often as desired; configure periodic shipment of diabetes supplies by care providers or patients (within policy limits etc.); order additional supplies on demand for reasons such as: extra supplies for trips, lost or damaged supplies, change in consumption, change in meters, or the like. Supplies can also include ancillary items such as syringes, tape, ketone test sticks, or the like. Further embodiments may permit users to order pump accessories and other merchandise.
  • Typical training modules include, but are not limited to: a diabetes primer; basic insulin pump operation; advanced insulin pump operation; operation of other devices; carbohydrate counting; problem troubleshooting; avoiding hypoglycemia; sick day guidelines; infusion site management.
  • the carbohydrate calculator would include a large database of common food items, a meal planner, and ability to transfer calculations easily to patient records in the medical information management system and connected medical device.
  • the integrated medical information management system utilizes E-mail messages that are sent to notify or remind patients of various items.
  • Typical preprogrammed Emails could include items such as: notification to upload device data; notification of an upcoming care provider appointment / reminder to schedule appointment; notification to order supplies / check inventory; clinical or technical service bulletins; customer satisfaction surveys, or the like.
  • the timing and specific content of these email messages will be configurable by either the patient, the health care provider, the managed care (HMOs) provider, all of the above, or the like.
  • the service will offer a general reminder facility that can be used to send arbitrary reminder email messages related to diabetes care. Both care providers and patients may configure the service to provide reminders.
  • the system may also be configured to generate (or suggest) automatic reminders based on uploaded data (e.g. remind the patient to test 3:00 AM blood glucose 2 times per week).
  • a user uses a continuous glucose monitor to monitor a patient for hypoglycemic condition, and action is taken when such a condition is detected.
  • the glucose monitor receiving device would be connected to a communication device (such as that shown in U.S. Patent application Serial No. 09/377,472 filed August 19, 1999 and entitled "Telemetered Characteristic Monitor System and Method of Using the Same (published as PCT publication WO 00/18449) which is herein incorporated by reference) which would monitor the glucose level and initiate communication with the integrated medical information management system if a preset level is reached.
  • the integrated medical information management system would then take a selected action such as notifying a family member, health care provider, or emergency services.
  • a data file uploaded from a patient's infusion device or other device will be transmitted to a clinical services department to assist in diagnosing potential product or configuration problems.
  • the ability for clinical services to interrogate an infusion device pump remotely in real time may be an option.
  • Data transmission will employ a flexible and robust protocol that will integrate data from multiple types of devices and can be extended to new devices and data types.
  • This protocol will isolate all but the lowest layers of software from the details of the specific devices.
  • This protocol will incorporate a data format that is suitable for storage in files. Such files could be stored for archival purposes, sent via email for store-and-forward transmission of data. etc.
  • Fig. 7 is a block diagram illustrating the structure of a data bus 400 utilized in embodiments of the integrated medical information management system.
  • the data bus includes data elements 402 that includes various data values 410, as well as date and time 404, and other information (such as data type 406, device information 408), or the like.
  • the data elements 402 may be linked together as collections 416 of data elements.
  • the data bus 400 may also include collections of data elements 412 with groupings of data elements, which aggregate related data elements (such as data elements 402) together in various forms.
  • the collections of data elements 412 can include data elements 402, and collection information 414 that link the collection of data elements 412 together, or the like.
  • the data bus 400 also includes a database interface 418 for interfacing with a database, as described above. Use of these data bus elements permits a user to connect different devices independent of a detailed knowledge of the data structure for each device.
  • Natural This term refers to the idea that a programmer can write code easily without undue complexity or regular reference to documentation. To a programmer familiar with the system, the resulting code should be readable almost like English.
  • Transparent This term refers to the idea that data can be manipulated without regard to the specific values or organization of the data itself, or of its origin. High level operations are supported without complex control structures. This is best accomplished by encapsulating as many details as possible in lower layers of the architecture.
  • the data bus 400 is implemented as a collection of classes (i.e. object definitions), which are used internally by the integrated medical information management system and other software applications for collection, transmission, storage, analysis, and reporting of data.
  • classes i.e. object definitions
  • the data bus 400 is implemented as a collection of classes (i.e. object definitions), which are used internally by the integrated medical information management system and other software applications for collection, transmission, storage, analysis, and reporting of data.
  • object definitions i.e. object definitions
  • only the lowest layers of device communication modules will perform any device specific processing. Generally, some of the reporting functions will require device specific knowledge, but this dependency will be kept to a minimum, and data from multiple devices will be able to be combined transparently. Programmers using the data bus are able to save combinations of different types of data from one or more devices into the database with a simple, one line operation. No special formatting or conversion will be required.
  • Data may also be retrieved from the database transparently based on a variety of criteria such as device type (infusion device, monitor, meter, or the like) or date/time range.
  • the data bus 400 is designed to make data manipulation easy and as independent of device specific constraints as possible.
  • the basic intent is to give programmers a powerful set of tools to allow them to work with the data to produce complex reports by writing a small amount of natural code. For example, the programmer can express a computation such as: "find all blood glucose readings over the last week and compute the average values by time buckets across a generic (modal) day” with just a few lines of code.
  • This computation is complex in that it encapsulates a parameterized database retrieval, a transformation to convert date/time stamps to time stamps only, a collection of data into buckets, and multiple averaging computations.
  • the data bus 400 will also integrate closely with the report layout and rendering subsystems such that these systems will share a common language, object definitions, and data structures.
  • the data bus data structures contain the report data along with the source data in a structure that closely mirrors the actual report.
  • These data structures and the Application Programming Interface provided to access the data structure will allow the report generation mechanism to interact with the data structure in a very simple manner to extract the data for the report.
  • individual data elements 402 represent the data on the data bus 400 as a fundamental unit of device or other data.
  • the data elements 402 consist of a date/time stamp, and a value, and they are associated with a particular physical device and a particular patient.
  • Individual data elements are typically utilized with the data bus as follows: a) created by a device object as part of an upload operation. Data elements
  • New data elements 402 or collections of data elements 412 may be created by the results of computations or transformations; and f) output onto a report via a report generation mechanism, which traverses the data structure created by the report logic.
  • collections of data elements 412 serve two purposes: a) represent a collection of data elements 402 that have been collected or summarized based on some criteria (collection of data elements 412 can be used as containers to create arbitrary hierarchies of data); and b) represent a computation or transformation on a data elements 402 or set of data elements 402.
  • the following steps generally describe to flow of data along the data bus:
  • Collection An object representing a specific device type communicates with a device to upload the device's information, and then creates a collection of data elements 402 representing the uploaded information, along with other information about the device and upload operation.
  • Transmission - A set of these collections are uploaded from a remote computer or other device to a server where the Applications are running.
  • Storage - A program on the server collects the transferred information and stores it in the database.
  • the reporting application determines the appropriate report to generate. Based on the type of report, the application extracts data from the database as one or more collection of data elements 402.
  • Reports are made up of individual report components organized hierarchically (some components may perform their own data retrieval operations). Report components can be broken down into two basic types: charts and numerical/tabular information. Preferably, each component uses data bus elements and custom logic to organize the report data as appropriate for the report, and to perform computations on the data. The results of these computations are stored in the report data structure. In general, the report data structures closely mirror the structure of the report itself.
  • each report component is instructed to generate its sub-report.
  • the report generation is accomplished using templates for each report component.
  • the instructions for extracting information from the data structure for tabular reports can be embedded in the component template itself without additional computation or logic. Charts are more complex, and thus each chart generally requires some amount of specific data manipulation and chart formatting logic.

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Abstract

Cette invention concerne un système de gestion intégrée de l'information médicale comprenant au moins un serveur central en ligne et au moins un terminal d'accès à distance. Ce terminal permet d'accéder de manière interactive à des données médicales concernant au moins un patient à partir du serveur central en ligne dans le but de produire des rapports interactifs à partir des données médicales concernant au moins un patient sur le terminal d'accès. Le serveur central en ligne est de préférence relié au terminal d'accès via une connexion Internet et un navigateur Internet.
PCT/US2000/013983 1999-05-20 2000-05-22 Systeme de gestion integree de l'information medicale WO2000072181A2 (fr)

Priority Applications (4)

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JP2000620504A JP2003500744A (ja) 1999-05-20 2000-05-22 総合的医療情報管理システム
EP00937654A EP1194864A2 (fr) 1999-05-20 2000-05-22 Systeme de gestion integree de l'information medicale
AU52797/00A AU5279700A (en) 1999-05-20 2000-05-22 Integrated medical information management system
CA002372656A CA2372656A1 (fr) 1999-05-20 2000-05-22 Systeme de gestion integree de l'information medicale

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US60/134,981 1999-05-20
US40901499A 1999-09-29 1999-09-29
US09/409,014 1999-09-29

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AU5279700A (en) 2000-12-12
EP1194864A2 (fr) 2002-04-10

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