WO2000063679A3 - Anordnung zur auswertung von fluoreszenzbasierten nachweisreaktionen - Google Patents

Anordnung zur auswertung von fluoreszenzbasierten nachweisreaktionen Download PDF

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Publication number
WO2000063679A3
WO2000063679A3 PCT/EP2000/003307 EP0003307W WO0063679A3 WO 2000063679 A3 WO2000063679 A3 WO 2000063679A3 EP 0003307 W EP0003307 W EP 0003307W WO 0063679 A3 WO0063679 A3 WO 0063679A3
Authority
WO
WIPO (PCT)
Prior art keywords
arrangement
based analytical
analytical reactions
fluorescence
cover
Prior art date
Application number
PCT/EP2000/003307
Other languages
English (en)
French (fr)
Other versions
WO2000063679A2 (de
Inventor
Wolfgang Bathe
Peter Kuehn
Dieter Schau
Alexander L Friedman
Albert H Gough
Original Assignee
Zeiss Carl Jena Gmbh
Cellomicstm Inc
Wolfgang Bathe
Peter Kuehn
Dieter Schau
Alexander L Friedman
Albert H Gough
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeiss Carl Jena Gmbh, Cellomicstm Inc, Wolfgang Bathe, Peter Kuehn, Dieter Schau, Alexander L Friedman, Albert H Gough filed Critical Zeiss Carl Jena Gmbh
Priority to EP00920699A priority Critical patent/EP1169634A2/de
Priority to JP2000612732A priority patent/JP4179753B2/ja
Publication of WO2000063679A2 publication Critical patent/WO2000063679A2/de
Publication of WO2000063679A3 publication Critical patent/WO2000063679A3/de
Priority to HK02104911.6A priority patent/HK1045188A1/zh
Priority to US11/109,898 priority patent/US20050196325A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Optical Measuring Cells (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

Anordnung zur Auswertung von fluoreszenzbasierten Nachweisreaktionen in durchsichtigen Probengefässen, wobei die Anregung und Abbildung der Fluoreszenz durch den Gefässboden hindurch erfolgt und die Proben von oben eingebracht werden, wobei eine die Probengefässe nach oben abschliessende verstellbare Abdeckung vorgesehen ist, die zur Probeneinführung mindestens eine Öffnung aufweist und die nur während des Einfüllvorganges oberhalb der zur Einfüllung vorgesehenen Probengefässe positioniert ist und/oder nur während des Einfüllvorgangs geöffnet ist.
PCT/EP2000/003307 1999-04-14 2000-04-13 Anordnung zur auswertung von fluoreszenzbasierten nachweisreaktionen WO2000063679A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00920699A EP1169634A2 (de) 1999-04-14 2000-04-13 Anordnung zur auswertung von fluoreszenzbasierten nachweisreaktionen
JP2000612732A JP4179753B2 (ja) 1999-04-14 2000-04-13 蛍光による検出反応の分析装置および分析方法
HK02104911.6A HK1045188A1 (zh) 1999-04-14 2002-06-28 對基於熒光的分析反應進行評估的裝置
US11/109,898 US20050196325A1 (en) 1999-04-14 2005-04-19 Arrangement for the evaluation of fluorescence-based detection reactions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19916748.6 1999-04-14
DE19916748A DE19916748A1 (de) 1999-04-14 1999-04-14 Anordnung und Auswertung von fluoreszenzbasierten Nachweisreaktionen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/109,898 Continuation US20050196325A1 (en) 1999-04-14 2005-04-19 Arrangement for the evaluation of fluorescence-based detection reactions

Publications (2)

Publication Number Publication Date
WO2000063679A2 WO2000063679A2 (de) 2000-10-26
WO2000063679A3 true WO2000063679A3 (de) 2001-01-11

Family

ID=7904471

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/003307 WO2000063679A2 (de) 1999-04-14 2000-04-13 Anordnung zur auswertung von fluoreszenzbasierten nachweisreaktionen

Country Status (6)

Country Link
US (1) US20050196325A1 (de)
EP (1) EP1169634A2 (de)
JP (1) JP4179753B2 (de)
DE (1) DE19916748A1 (de)
HK (1) HK1045188A1 (de)
WO (1) WO2000063679A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6683735B2 (en) 2000-11-17 2004-01-27 Universal Imaging Corporation Rapidly changing dichroic beamsplitter in epifluorescent microscopes

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DE10157511A1 (de) * 2001-11-23 2003-06-12 Evotec Ag Verfahren und Vorrichtung zur Korrektur der Größe und/oder Form eines Messvolumens in einer chemischen und/oder biologischen Probe
WO2005031322A1 (ja) 2003-09-26 2005-04-07 Nikon Corporation 環境保持装置および環境制御型分析装置
DE102004016361B4 (de) 2004-04-01 2006-07-06 Cybio Ag Optisches Analysenmessgerät für Fluoreszenzmessungen an Multiprobenträgern
DE102004020591A1 (de) * 2004-04-27 2005-11-17 Carl Zeiss Jena Gmbh Meßvorrichtung
WO2008007725A1 (fr) * 2006-07-12 2008-01-17 Toyo Boseki Kabushiki Kaisha Analyseur et son utilisation
US20080180793A1 (en) * 2007-01-26 2008-07-31 Cellomics, Inc. High content screening system with live cell chamber
US9557217B2 (en) 2007-02-13 2017-01-31 Bti Holdings, Inc. Universal multidetection system for microplates
US9322784B2 (en) 2010-09-08 2016-04-26 Tecan Trading Ag Microplate-reader with a controlled gas atmosphere, corresponding method and use of same
CH703700A2 (de) * 2010-09-08 2012-03-15 Tecan Trading Ag Kontrolle der Gasatmosphäre in Mikroplatten-Readern.
CH706326A2 (de) * 2012-03-14 2013-09-30 Tecan Trading Ag Verfahren und Mikroplatten-Reader zum Untersuchung von biologischen Zellen oder Zellkulturen.
DE102014213348A1 (de) 2014-07-09 2016-01-14 Carl Zeiss Microscopy Gmbh Durchlichtmikroskop und Verfahren zur Durchlichtmikroskopie
CN113203693A (zh) * 2021-04-25 2021-08-03 浙江大学 高通量手持自动光谱检测仪
DE102021114565B3 (de) 2021-06-07 2022-09-08 Leica Microsystems Cms Gmbh Mikroskop und Verfahren zum Betreiben eines Mikroskops

Citations (5)

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Publication number Priority date Publication date Assignee Title
EP0287005A2 (de) * 1987-04-11 1988-10-19 Kabushiki Kaisha Kyoto Daiichi Kagaku Verfahren zur chemischen Analysierung unter Verwendung einer Testvorrichtung einer Probe
WO1992014137A1 (en) * 1991-02-05 1992-08-20 Biohit Oy Procedure and apparatus for determining the fluorescence of a liquid sample
US5207987A (en) * 1990-05-21 1993-05-04 Pb Diagnostic Systems Inc. Temperature controlled chamber for diagnostic analyzer
US5578272A (en) * 1992-04-09 1996-11-26 Hoffmann-La Roche Inc. Reagent kit and analyzer
DE19824117A1 (de) * 1997-05-30 1998-12-03 Bernd Dr Steinbrenner Schiebedeckel sowie Box

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1486210A (en) * 1973-11-14 1977-09-21 Suovaniemi Osmo Antero Cuvette assembly for use in automatic reading and recording of reaction results
US3964864A (en) * 1974-11-18 1976-06-22 Harald Dahms Method and apparatus for measuring CO2, O2, and Cl in body fluids
DD149574A1 (de) * 1980-03-25 1981-07-15 Uwe Karsten Anordnung fuer serienmaessige fluoreszenzmessung
DE3110239A1 (de) * 1981-03-17 1982-10-07 Seppo 32780 Titusville Fla. Kolehmainen Verfahren und vorrichtung zum messen der lumineszenz von proben
DE3915421C2 (de) * 1989-05-11 1995-03-02 Bayer Ag Vorrichtung zur Messung der Fluoreszenzanregung biologischer Zellen bei zwei verschiedenen Wellenlängen
DE4123817C2 (de) * 1991-07-18 1994-06-09 Berthold Lab Prof Dr Strahlungsmeßgerät, insbesondere zur Messung der Lumineszenz
US5355215A (en) * 1992-09-30 1994-10-11 Environmental Research Institute Of Michigan Method and apparatus for quantitative fluorescence measurements
FI954511A0 (fi) * 1995-09-22 1995-09-22 Labsystems Oy Fluorometer
US5792431A (en) * 1996-05-30 1998-08-11 Smithkline Beecham Corporation Multi-reactor synthesizer and method for combinatorial chemistry

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287005A2 (de) * 1987-04-11 1988-10-19 Kabushiki Kaisha Kyoto Daiichi Kagaku Verfahren zur chemischen Analysierung unter Verwendung einer Testvorrichtung einer Probe
US5207987A (en) * 1990-05-21 1993-05-04 Pb Diagnostic Systems Inc. Temperature controlled chamber for diagnostic analyzer
WO1992014137A1 (en) * 1991-02-05 1992-08-20 Biohit Oy Procedure and apparatus for determining the fluorescence of a liquid sample
US5578272A (en) * 1992-04-09 1996-11-26 Hoffmann-La Roche Inc. Reagent kit and analyzer
DE19824117A1 (de) * 1997-05-30 1998-12-03 Bernd Dr Steinbrenner Schiebedeckel sowie Box

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6683735B2 (en) 2000-11-17 2004-01-27 Universal Imaging Corporation Rapidly changing dichroic beamsplitter in epifluorescent microscopes

Also Published As

Publication number Publication date
US20050196325A1 (en) 2005-09-08
DE19916748A1 (de) 2000-10-19
JP4179753B2 (ja) 2008-11-12
HK1045188A1 (zh) 2002-11-15
JP2002542481A (ja) 2002-12-10
WO2000063679A2 (de) 2000-10-26
EP1169634A2 (de) 2002-01-09

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