WO2000060950A1 - Dietary supplement derived from fermented milks for the prevention of osteoporosis - Google Patents
Dietary supplement derived from fermented milks for the prevention of osteoporosis Download PDFInfo
- Publication number
- WO2000060950A1 WO2000060950A1 PCT/IT2000/000130 IT0000130W WO0060950A1 WO 2000060950 A1 WO2000060950 A1 WO 2000060950A1 IT 0000130 W IT0000130 W IT 0000130W WO 0060950 A1 WO0060950 A1 WO 0060950A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- weight
- lactobacillus
- milk
- mixture
- granules
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
- A23C9/1232—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt in powdered, granulated or dried solid form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/127—Fermented milk preparations; Treatment using microorganisms or enzymes using microorganisms of the genus lactobacteriaceae and other microorganisms or enzymes, e.g. kefir, koumiss
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
- A23C9/1322—Inorganic compounds; Minerals, including organic salts thereof, oligo-elements; Amino-acids, peptides, protein-hydrolysates or derivatives; Nucleic acids or derivatives; Yeast extract or autolysate; Vitamins; Antibiotics; Bacteriocins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Definitions
- the present invention relates to products used as dietary supplements or nutritional supplements for the supplementation of nutrition and diets by taking substances, mainly of natural origin, which supply elements necessary for nutrition and thus for good maintenance of essential body functions (such as the formation and preservation of the bones, muscles, skin, its related tissues and the like).
- the present invention relates to a process for obtaining a natural dietary supplement which has proved very effective in the prevention and treatment of osteoporosis and of other diseases mainly due to calcium, magnesium and potassium deficiencies in the body.
- diets rich in milk and cheese products are often recommended; these provide a good supply of calcium (and also magnesium), but unfortunately present many problems which are often underestimated, such as: a) problems of poor digestibility or even of lactose intolerance; b) excessively high cholesterol levels; c) unwanted intake of calories and fats.
- the inventor of the present invention therefore sought a solution which would yield a product better able to overcome the above- mentioned problems, in the form of a supplement which was demonstrably efficacious, reliable and inexpensive, that is to say by developing a product which: 1) guarantees the supply of adequate amounts of calcium, magnesium and other nutrients which are useful for the bones and metabolism for the purposes of the musculoskeletal functions; 2) ensures assimilation of the various nutrients; 3) assures digestibility and avoids intolerance; and 4) possesses the characteristics of a wholly biocompatible biological substance.
- the present invention also relates to the dietary supplements obtainable with said process and their use for the prevention and therapy of osteoporosis and of other diseases due substantially to calcium, magnesium and potassium deficiencies.
- the process according to the invention makes it possible to obtain a "nutrient complex", by which definition is meant a nutritional substance of natural origin, which is the result of biological processing by micro-organisms (the so-called “beneficial micro-organisms”, such as lactobacilli, etc.), containing all the nutrients desired, and particularly calcium, magnesium and potassium, with the desired characteristics of good assimilation, tolerability and efficacy.
- the inventor started out by selecting the products obtainable from various types of fermented milk, products which differ both in the type of milk (cow, sheep, goat, mare) and the type of micro-organisms used, as well as in the modalities whereby the fermentation process itself is conducted.
- Kefir is a kind of yoghurt, obtainable by fermentation of milk through the dual action of a number of lactobacilli and yeasts, the appropriate combination of which makes it possible to obtain a biologically processed product with the required characteristics.
- desired substances for example, though not exclusively, calcium
- desired substances allows “enrichment” of the nutrient complex so that it can be used specifically for a certain type of application (for example, for the treatment of osteoporosis). It is the micro-organisms that process one or more minerals, fixing them in their cells and ensuring their bioavailability.
- a dietary supplement obtained by means of the process according to the present invention as a result of the broad spectrum and high concentrations of organic substances with beneficial effects that it contains, not only proves useful as a primary measure, as indicated earlier, for the prevention and therapy of conditions due to calcium, magnesium and potassium deficiencies, but also exerts a secondary beneficial action on various other disorders generated by genetic factors in conjunction with functional imbalances of a chemical nature.
- This process comprises essentially the following steps: a) preparing a mixture at 18°C comprising one or more types of pasteurised milks of animal origin; b) adding to said mixture 1.5 - 4.5% by weight of first granules consisting prevailingly of bacteria; c) holding the mixture at 18-25°C for an initial time period ranging from 6 to 12 hours and subsequently adding, after approximately half the process, 1-3% by weight of said pasteurised milk mixture; d) adding to the mixture 2.5-6.5% by weight of second granules consisting prevailingly of yeasts; e) holding the mixture thus obtained at 18-25°C for a second time period ranging from 6 to 12 hours and adding thereto calcium and/or magnesium and/or potassium in amounts of 0.2-1.2% by weight during the first half of said second time period; f) filtering off a residual matrix consisting of the granules introduced in the various steps of the process and the granules formed during the process itself; g) drying the mixture after said filtration so as to obtain
- Said first and second granules can be obtained by means of a conventional-type milk inoculation process, starting from commercially available Kefir granules.
- a conventional-type milk inoculation process starting from commercially available Kefir granules.
- reference can be made to the texts by M. Motaghi et al. (1997), Kandler-Weiss (1986) and Hardle (1986) for said first granules consisting mainly of bacteria, and to the method of Barnet (1990) for the second granules consisting mainly of yeasts. All the aforesaid publications are incorporated herein by reference.
- An indicative profile of the contents of said granules can be deduced from the attached Tables A and B.
- Lactobacillus kefir 10 8 -10 9 (optionally, "addition” of 20-30%)
- Lactobacillus kefiraiiofaciens 10 7 -10 « (optionally, "addition” of 20-30%)
- said dietary supplement surprisingly presents a profile which is much richer in other "noble" substances, as an adjunct to the specific supplementation and of general value, such as branched-chain amino acids, polysaccharides and vitamins. These nutrients have been shown to significantly enhance the intestinal absorption of calcium and the metabolism of various minerals.
- polysaccharides slow-uptake carbohydrates
- branched-chain amino acids are also important elements for elderly subjects by virtue of their basic function in the growth and maintenance of muscle fibres (thereby again providing additional support for the entire musculoskeletal system).
- Tables 1 to 5 an example is given (Tables 1 to 5) of a formulation (nutrient complex) selected using a fermentation process according to the invention, aimed at providing supplementation of minerals such as calcium, magnesium and potassium, according to the criteria of the invention itself; this is followed by the presentation (Table 6) of the composition of a dietary supplement, produced by means of "targeted enrichment" of the starting substance and suitable for preventive and therapeutic applications in the field of osteoporosis:
- composition of fermentation substances obtained by means of the process according to the invention.
- Vitamins (mg per 100 g product)
- the dietary supplements produced via the process of the present invention have been extensively tried and tested, demonstrating that they effectively possess the characteristics desired, which allow remarkable advantages over traditional calcium supplements to be obtained.
- the main advantages which are particularly worth mentioning are as follows:
- the substance obtainable by lyophilisation as a dry powder with an agreeable taste, is presented in very practical formulations, such as chewable tablets and sachets with the contents to be dissolved in liquids, which, amongst other things, also allow high doses of product to be administered by once-daily administration. This is also because the formulation obtained makes any form of delayed or slow-release of the substance contained superfluous.
- the formulation derived from the "Kefir-type” fermentation process has proved ideal - thereby differing totally from the other calcium and mineral supplements - for constituting a multifunctional "substrate” as a basis for producing dietary supplements in various areas of application for preventive and/or support treatment in various deficiency conditions (poorly nutritional diets, metabolic dysfunctions), immunodeficient states, degenerative diseases (of the bones, dystrophy of the skin), senility, physiological transition periods (menopause).
Abstract
Description
Claims
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SK1886-2000A SK18862000A3 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
DE60005104T DE60005104T2 (en) | 1999-04-13 | 2000-04-07 | DIET ADDITIVE FROM FERMENTED MILK PRODUCTS FOR PREVENTING ÖSTEOPOROSIS |
US09/719,170 US6511685B1 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
HU0103895A HUP0103895A3 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
AT00922846T ATE249147T1 (en) | 1999-04-13 | 2000-04-07 | DIET SUPPLEMENT FROM FERMENTED MILK PRODUCTS TO PREVENT ESTEOPOROSIS |
CA002334877A CA2334877C (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
KR1020007013800A KR20010072587A (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
EEP200000713A EE200000713A (en) | 1999-04-13 | 2000-04-07 | Dietary supplement from fermented milk to prevent osteoporosis |
AU43118/00A AU775104B2 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
IL13985300A IL139853A0 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
JP2000610300A JP4231208B2 (en) | 1999-04-13 | 2000-04-07 | Nutritional supplements derived from fermented milk for the prevention of osteoporosis |
EP00922846A EP1085816B1 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
BR0006040-2A BR0006040A (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milk for the prevention of osteoporosis |
PL00344670A PL344670A1 (en) | 1999-04-13 | 2000-04-07 | Osteoporosis preventing nourishment additive obtained from fermented milk |
DK00922846T DK1085816T3 (en) | 1999-04-13 | 2000-04-07 | Supplements derived from fermented milk to prevent osteoporosis |
IS5741A IS5741A (en) | 1999-04-13 | 2000-11-28 | Nutritional supplements derived from fermented milk to prevent osteoporosis |
NO20006284A NO20006284L (en) | 1999-04-13 | 2000-12-11 | Supplements derived from fermented milk to prevent osteoporosis |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH683/99 | 1999-04-13 | ||
CH68399 | 1999-04-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000060950A1 true WO2000060950A1 (en) | 2000-10-19 |
Family
ID=4192730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IT2000/000130 WO2000060950A1 (en) | 1999-04-13 | 2000-04-07 | Dietary supplement derived from fermented milks for the prevention of osteoporosis |
Country Status (24)
Country | Link |
---|---|
US (1) | US6511685B1 (en) |
EP (1) | EP1085816B1 (en) |
JP (1) | JP4231208B2 (en) |
KR (1) | KR20010072587A (en) |
CN (1) | CN1300187A (en) |
AR (1) | AR023477A1 (en) |
AT (1) | ATE249147T1 (en) |
AU (1) | AU775104B2 (en) |
BR (1) | BR0006040A (en) |
CA (1) | CA2334877C (en) |
DE (1) | DE60005104T2 (en) |
DK (1) | DK1085816T3 (en) |
EE (1) | EE200000713A (en) |
ES (1) | ES2204569T3 (en) |
HU (1) | HUP0103895A3 (en) |
IL (1) | IL139853A0 (en) |
IS (1) | IS5741A (en) |
NO (1) | NO20006284L (en) |
PL (1) | PL344670A1 (en) |
PT (1) | PT1085816E (en) |
SK (1) | SK18862000A3 (en) |
TN (1) | TNSN00078A1 (en) |
TR (1) | TR200003689T1 (en) |
WO (1) | WO2000060950A1 (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001028547A1 (en) * | 1999-10-19 | 2001-04-26 | Meiji Milk Products Co., Ltd | Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials |
WO2003090546A1 (en) * | 2002-04-23 | 2003-11-06 | Jafar Mahdavi | Multicultural fermented yogurt |
WO2007004966A1 (en) * | 2005-07-05 | 2007-01-11 | Probi Ab | USE OF LACTOBACILLUS FOR INCREASING THE ABSORPTION OF A METAL CHOSEN FROM Fe, Zn, Ca AND IONS THEREOF |
EP1806976A1 (en) * | 2004-10-22 | 2007-07-18 | Unilever N.V. | Granular cooking aid comprising microbial encapsulates, and cubes and tablets comprising such granular cooking aid |
ITMI20122267A1 (en) * | 2012-12-28 | 2014-06-29 | Granarolo S P A | FLAVORING BLEND FOR THE PRODUCTION OF MOZZARELLE. |
US9968124B2 (en) | 2007-05-09 | 2018-05-15 | Nestec S.A. | Freeze-dried, aerated fruit or vegetable compositions and methods of making thereof |
US10159261B2 (en) | 2007-05-09 | 2018-12-25 | Nestec S. A. | Freeze-dried, aerated dairy or dairy-substitute compositions and methods of making thereof |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0217225D0 (en) * | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicinal compounds |
RU2338511C2 (en) * | 2003-04-09 | 2008-11-20 | Дольхаи Клиника Эгесшегидьи Кфт. | Composition for sexual hygiene |
JP5048246B2 (en) * | 2003-08-26 | 2012-10-17 | 日本ケフィア株式会社 | Internal composition for skin care |
DE102005053725A1 (en) * | 2005-11-10 | 2007-05-24 | St. Leonhardsquelle Gmbh & Co. Kg | Dairy product comprising mare's milk and goat's milk, process for its preparation and its use |
KR100940125B1 (en) * | 2007-08-24 | 2010-02-02 | 국민대학교산학협력단 | Composition for Improving Bone Metabolism Comprising Milk Component Fermented by Latobacillus casei |
DE102017202134A1 (en) | 2017-02-10 | 2018-08-16 | Intercell Pharma Gmbh | A preparation for the treatment of the adverse side effects of gastric acid blockers |
TWI604052B (en) | 2017-02-20 | 2017-11-01 | 景岳生物科技股份有限公司 | Lactobacillus plantarum strain gmnl-662 and composition having the same for promoting bone regrowth |
CN108624520B (en) * | 2017-03-16 | 2022-01-25 | 景岳生物科技股份有限公司 | Lactobacillus plantarum strain GMNL-662 for promoting bone regeneration and composition thereof |
CN108486018B (en) * | 2018-05-03 | 2021-05-11 | 上海理工大学 | Lactobacillus brevis capable of relieving bone resorption symptom |
CA3111795A1 (en) | 2018-09-05 | 2020-03-12 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases |
EP3986163A2 (en) * | 2019-06-19 | 2022-04-27 | Solarea Bio, Inc. | Microbial compositions and methods for producing upgraded probiotic assemblages |
WO2023092150A1 (en) * | 2021-11-22 | 2023-05-25 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1349300A (en) * | 1962-11-27 | 1964-01-17 | Eurorga | Food product from milk |
EP0148300A1 (en) * | 1984-01-10 | 1985-07-17 | Bio-Industries Gmbh Sanofi | Process for preparing kefir |
GB2184334A (en) * | 1985-10-08 | 1987-06-24 | Sennosuke Tokumaru | Lyophilised kefir yoghurt |
EP0346884A2 (en) * | 1988-06-16 | 1989-12-20 | Yakult Honsha Co., Ltd. | Production process of kefir-like fermented milk |
WO1992013462A1 (en) * | 1991-02-08 | 1992-08-20 | Rochade | Method of manufacturing a novel lactic leaven, new leaven obtained, manufacture of food products from said leaven and products obtained |
JPH09191852A (en) * | 1996-01-19 | 1997-07-29 | Sennosuke Tokumaru | Healthy food |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4902517A (en) * | 1987-12-28 | 1990-02-20 | The Calpis Food Industry Co., Ltd. | Processes for producing milk-derived alcoholic beverages |
US5820903A (en) * | 1997-06-30 | 1998-10-13 | General Mills, Inc. | Calcium fortified yogurt and methods of preparation |
US6368591B2 (en) * | 1998-05-15 | 2002-04-09 | Shanghai Sine Pharmaceutical Corporation Ltd. | Beneficial microbe composition, new protective materials for the microbes, method to prepare the same and uses thereof |
-
2000
- 2000-04-07 IL IL13985300A patent/IL139853A0/en unknown
- 2000-04-07 EP EP00922846A patent/EP1085816B1/en not_active Expired - Lifetime
- 2000-04-07 CN CN00800578A patent/CN1300187A/en active Pending
- 2000-04-07 PT PT00922846T patent/PT1085816E/en unknown
- 2000-04-07 PL PL00344670A patent/PL344670A1/en unknown
- 2000-04-07 JP JP2000610300A patent/JP4231208B2/en not_active Expired - Fee Related
- 2000-04-07 SK SK1886-2000A patent/SK18862000A3/en unknown
- 2000-04-07 DK DK00922846T patent/DK1085816T3/en active
- 2000-04-07 DE DE60005104T patent/DE60005104T2/en not_active Expired - Lifetime
- 2000-04-07 BR BR0006040-2A patent/BR0006040A/en not_active Application Discontinuation
- 2000-04-07 US US09/719,170 patent/US6511685B1/en not_active Expired - Fee Related
- 2000-04-07 EE EEP200000713A patent/EE200000713A/en unknown
- 2000-04-07 ES ES00922846T patent/ES2204569T3/en not_active Expired - Lifetime
- 2000-04-07 CA CA002334877A patent/CA2334877C/en not_active Expired - Fee Related
- 2000-04-07 AU AU43118/00A patent/AU775104B2/en not_active Ceased
- 2000-04-07 HU HU0103895A patent/HUP0103895A3/en unknown
- 2000-04-07 TR TR2000/03689T patent/TR200003689T1/en unknown
- 2000-04-07 WO PCT/IT2000/000130 patent/WO2000060950A1/en not_active Application Discontinuation
- 2000-04-07 AT AT00922846T patent/ATE249147T1/en not_active IP Right Cessation
- 2000-04-07 KR KR1020007013800A patent/KR20010072587A/en not_active Application Discontinuation
- 2000-04-13 AR ARP000101708A patent/AR023477A1/en unknown
- 2000-04-13 TN TNTNSN00078A patent/TNSN00078A1/en unknown
- 2000-11-28 IS IS5741A patent/IS5741A/en unknown
- 2000-12-11 NO NO20006284A patent/NO20006284L/en not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1349300A (en) * | 1962-11-27 | 1964-01-17 | Eurorga | Food product from milk |
EP0148300A1 (en) * | 1984-01-10 | 1985-07-17 | Bio-Industries Gmbh Sanofi | Process for preparing kefir |
GB2184334A (en) * | 1985-10-08 | 1987-06-24 | Sennosuke Tokumaru | Lyophilised kefir yoghurt |
EP0346884A2 (en) * | 1988-06-16 | 1989-12-20 | Yakult Honsha Co., Ltd. | Production process of kefir-like fermented milk |
WO1992013462A1 (en) * | 1991-02-08 | 1992-08-20 | Rochade | Method of manufacturing a novel lactic leaven, new leaven obtained, manufacture of food products from said leaven and products obtained |
JPH09191852A (en) * | 1996-01-19 | 1997-07-29 | Sennosuke Tokumaru | Healthy food |
Non-Patent Citations (2)
Title |
---|
CHEMICAL ABSTRACTS, vol. 127, no. 10, 8 September 1997, Columbus, Ohio, US; abstract no. 135020, XP002144915 * |
HAEFLIGER M ET AL: "KEFIR - EIN FASZINIERENDES SAUERMILCHPRODUKT", DEUTSCHE MOLKEREI ZEITUNG DMZ,DE,VOLKSWIRTSCHAFTLICHER VERLAG GMBH. MUNCHEN, vol. 112, no. 13, 28 March 1991 (1991-03-28), pages 370 - 372,374-37, XP000201310, ISSN: 0938-9369 * |
Cited By (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU780598B2 (en) * | 1999-10-19 | 2005-04-07 | Meiji Dairies Corporation | Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials |
WO2001028547A1 (en) * | 1999-10-19 | 2001-04-26 | Meiji Milk Products Co., Ltd | Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials |
US7709537B1 (en) | 1999-10-19 | 2010-05-04 | Meiji Dairiese Corporation | Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials |
WO2003090546A1 (en) * | 2002-04-23 | 2003-11-06 | Jafar Mahdavi | Multicultural fermented yogurt |
EP1806976B1 (en) * | 2004-10-22 | 2014-01-29 | Unilever N.V. | Granular cooking aid comprising microbial encapsulates, and cubes and tablets comprising such granular cooking aid |
EP1806976A1 (en) * | 2004-10-22 | 2007-07-18 | Unilever N.V. | Granular cooking aid comprising microbial encapsulates, and cubes and tablets comprising such granular cooking aid |
US10105403B2 (en) | 2005-07-05 | 2018-10-23 | Probi Ab | Methods of treating iron deficiency to prevent iron-deficiency anemia by administration of Lactobacillus plantarum |
US9687513B2 (en) | 2005-07-05 | 2017-06-27 | Probi Ab | Methods of treating anemia and increasing the absorption of non-heme iron by administration of lactobacillus plantarum |
WO2007004966A1 (en) * | 2005-07-05 | 2007-01-11 | Probi Ab | USE OF LACTOBACILLUS FOR INCREASING THE ABSORPTION OF A METAL CHOSEN FROM Fe, Zn, Ca AND IONS THEREOF |
US9968124B2 (en) | 2007-05-09 | 2018-05-15 | Nestec S.A. | Freeze-dried, aerated fruit or vegetable compositions and methods of making thereof |
US10076133B2 (en) | 2007-05-09 | 2018-09-18 | Nestec S. A. | Freeze-dried aerated fruit and/or vegetable compositions and methods of making thereof |
US10154685B2 (en) | 2007-05-09 | 2018-12-18 | Nestec S.A. | Freeze-dried aerated fruit or vegetable compositions and methods of making thereof |
US10159261B2 (en) | 2007-05-09 | 2018-12-25 | Nestec S. A. | Freeze-dried, aerated dairy or dairy-substitute compositions and methods of making thereof |
US10206409B2 (en) | 2007-05-09 | 2019-02-19 | Nestec S. A. | Freeze-dried, dairy or dairy-substitute compositions and methods of making and using |
ITMI20122267A1 (en) * | 2012-12-28 | 2014-06-29 | Granarolo S P A | FLAVORING BLEND FOR THE PRODUCTION OF MOZZARELLE. |
WO2014102711A1 (en) * | 2012-12-28 | 2014-07-03 | Granarolo S.P.A. | Flavouring mixture for producing mozzarella |
Also Published As
Publication number | Publication date |
---|---|
PT1085816E (en) | 2004-02-27 |
EP1085816B1 (en) | 2003-09-10 |
JP2002540807A (en) | 2002-12-03 |
JP4231208B2 (en) | 2009-02-25 |
DE60005104T2 (en) | 2004-08-19 |
DK1085816T3 (en) | 2004-01-26 |
HUP0103895A3 (en) | 2003-02-28 |
SK18862000A3 (en) | 2001-06-11 |
NO20006284L (en) | 2001-01-29 |
ATE249147T1 (en) | 2003-09-15 |
KR20010072587A (en) | 2001-07-31 |
TR200003689T1 (en) | 2001-07-23 |
IL139853A0 (en) | 2002-02-10 |
IS5741A (en) | 2000-11-28 |
AR023477A1 (en) | 2002-09-04 |
NO20006284D0 (en) | 2000-12-11 |
US6511685B1 (en) | 2003-01-28 |
PL344670A1 (en) | 2001-11-19 |
CA2334877C (en) | 2009-06-16 |
DE60005104D1 (en) | 2003-10-16 |
CA2334877A1 (en) | 2000-10-19 |
CN1300187A (en) | 2001-06-20 |
ES2204569T3 (en) | 2004-05-01 |
EE200000713A (en) | 2002-04-15 |
HUP0103895A2 (en) | 2002-02-28 |
BR0006040A (en) | 2001-03-13 |
AU775104B2 (en) | 2004-07-15 |
TNSN00078A1 (en) | 2005-11-10 |
EP1085816A1 (en) | 2001-03-28 |
AU4311800A (en) | 2000-11-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6511685B1 (en) | Dietary supplement derived from fermented milks for the prevention of osteoporosis | |
US6596301B1 (en) | Anti-stress drugs and functional foods having anti-stress effects | |
CN103653170B (en) | Stachyose probiotics solid beverage | |
RU2549709C1 (en) | Probiotic sour cream production method | |
JPH03505520A (en) | Nutrient composition and its manufacturing method | |
JP2009507044A (en) | Milk-derived composition and use for enhancing muscle mass or strength | |
US6368641B1 (en) | Lactic acid bacteria and food products | |
WO1994017671A1 (en) | Biologically active soured milk product 'acidolact-narineh' and a process for producing the same | |
Goswami et al. | Implication of functional ingredients of goat milk to develop functional foods | |
JP2003310154A (en) | Method for fermenting soybean milk by using kefir grain and fermented product | |
CN101112210B (en) | Onion biological fermentation emulsion and the producing method thereof | |
CN102077872B (en) | Fruit vinegar-containing milk beverage and preparation method thereof | |
TWI761487B (en) | Fermented milk used to increase blood amino acid concentration | |
Novhorodska | Sour milk drink with prebiotic properties | |
RU2128444C1 (en) | Composition for preparing cultured milk proteinaceous product | |
MXPA00012300A (en) | Dietary supplement derived from fermented milks for the prevention of osteoporosis | |
JP3560309B2 (en) | Calcium absorption promoting nutritional composition | |
RU2196432C1 (en) | Composition for preparing cultured milk product for herodietary alimentation | |
RU2182794C2 (en) | Dairy beverage for gerontodietary nutrition | |
RU2789462C1 (en) | Ferrous milk product for gerodietic nutrition | |
TALKHANBAYEVA et al. | The Biological Value, Chemical Composition and Nutrition of the National TURKISH People Drinksas" Kumys" and" Shubat | |
BG515Y1 (en) | Tablet form of dietetic lactic acid product | |
CZ20004619A3 (en) | Dietary supplement derived from fermented milks for the prevention of osteoporosis | |
RU2552144C1 (en) | Low-fat cultured milk product for gerontological dietary alimentation | |
Mc Donagh et al. | Milk and dairy products for better human health |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 00800578.8 Country of ref document: CN |
|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
WWE | Wipo information: entry into national phase |
Ref document number: 139853 Country of ref document: IL |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020007013800 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 18862000 Country of ref document: SK |
|
WWE | Wipo information: entry into national phase |
Ref document number: PV2000-4619 Country of ref document: CZ Ref document number: 2000922846 Country of ref document: EP Ref document number: PA/a/2000/012300 Country of ref document: MX |
|
ENP | Entry into the national phase |
Ref document number: 2334877 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2000/03689 Country of ref document: TR |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 09719170 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 509277 Country of ref document: NZ |
|
WWP | Wipo information: published in national office |
Ref document number: 2000922846 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: PV2000-4619 Country of ref document: CZ |
|
WWP | Wipo information: published in national office |
Ref document number: 1020007013800 Country of ref document: KR |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
WWR | Wipo information: refused in national office |
Ref document number: PV2000-4619 Country of ref document: CZ |
|
WWG | Wipo information: grant in national office |
Ref document number: 2000922846 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1020007013800 Country of ref document: KR |