WO2000044286A1 - Dispositif d'echantillonnage et procede d'extraction d'un echantillon - Google Patents

Dispositif d'echantillonnage et procede d'extraction d'un echantillon Download PDF

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Publication number
WO2000044286A1
WO2000044286A1 PCT/US2000/002302 US0002302W WO0044286A1 WO 2000044286 A1 WO2000044286 A1 WO 2000044286A1 US 0002302 W US0002302 W US 0002302W WO 0044286 A1 WO0044286 A1 WO 0044286A1
Authority
WO
WIPO (PCT)
Prior art keywords
cannula
stylet
sample
core collector
axial channel
Prior art date
Application number
PCT/US2000/002302
Other languages
English (en)
Other versions
WO2000044286A9 (fr
Inventor
Michael K. Landi
Douglas Moreland
Original Assignee
Minrad Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minrad Inc. filed Critical Minrad Inc.
Priority to AU35849/00A priority Critical patent/AU3584900A/en
Priority to CA002360529A priority patent/CA2360529A1/fr
Priority to EP00914465A priority patent/EP1152695A4/fr
Priority to JP2000595593A priority patent/JP2002535064A/ja
Publication of WO2000044286A1 publication Critical patent/WO2000044286A1/fr
Publication of WO2000044286A9 publication Critical patent/WO2000044286A9/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A61B10/025—Pointed or sharp biopsy instruments for taking bone, bone marrow or cartilage samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws

Definitions

  • This invention relates to sampling devices and methods of retrieving a sample .
  • the device and method disclosed herein may be used to obtain a sample of bone from a patient.
  • the bone sample is left behind when the needle is withdrawn and no bone is obtained. If an inadequate sample is obtained, or if multiple samples are required, the procedure must be repeated, thereby increasing the cost of the procedure, exposing the patient and medical personnel to harmful x-rays, in the case where a fluoroscope is used to properly position the needle, and exposing the patient to additional risk corresponding to complications from the procedure.
  • the present invention includes a sampling device and a method of retrieving a sample.
  • the device includes a cannula having a first end and a second end. The first end has a threaded section.
  • the present invention also includes a method of obtaining a bone sample.
  • the method includes providing a stylet, providing a cannula having an axial channel, and inserting the stylet into the axial channel.
  • the stylet is connected to the cannula to form an assembly, and the assembly is inserted into a body to place an end of the cannula proximate to a sample location.
  • the stylet is disconnected, and the cannula is twisted to engage an end of the cannula in a part of the body.
  • the stylet is removed from the axial channel, and a core collector is inserted in place of the stylet.
  • the cannula is twisted to further engage the end of the cannula in the part of the body, and to embed a portion of the core collector in the part of the body, so that a sample to be retrieved resides in the core collector. Then, the core collector is disconnected from the cannula, and removed from the cannula.
  • Figure 1 is a side view of a cannula according to the present invention.
  • Figure 2 is a side view of a stylet according to the present invention.
  • Figure 3 is a side view of a core collector according to the present invention
  • Figure 4 is a cross-sectioned side view of a portion of the core collector
  • Figure 5 is a side view of a core ejector according to the present invention
  • Figure 6 is a cannula liner according to the present invention
  • Figures 7A and 7B show steps of a method according to the present invention
  • Figure 8 is a side view of a cannula assembled with a stylet according to the present invention.
  • Figure 9 is a side view of the core collector shown in Figure 3 assembled with the cannula shown in Figure l;
  • Figure 10 is a side view of the core ejector shown in Figure 5 being used to push a bone sample from the core collector shown in Figure 3;
  • Figure 11 shows pituitary forceps used in a method according to the present invention.
  • Figure 12 shows the pituitary forceps shown in Figure 11 inserted through the cannula shown in Figure 1.
  • FIG. 1 shows a cannula 10 according to the present invention.
  • the cannula 10 has a first end 13 having a threaded section 16 with a projecting helical rib 19.
  • the first end 13 may include a beveled tip 22, as shown in Figure 1.
  • the cannula 10 also has a second end 25 having a handle 28.
  • the second end 25 also includes an apparatus for connecting 31 the cannula 10, such as a pin lock connector, that permits the cannula 10 to be connected to another instrument.
  • the cannula 10 has an axial channel 34 extending between the first and second ends 13, 25 of the cannula.
  • FIG. 2 shows a stylet 37 according to the present invention.
  • the stylet 37 has a first end 40 with a sharpened point 43.
  • the stylet 37 has a second end 44 that may include a device for connecting 46 the stylet, such as a mating apparatus to the pin lock connector.
  • the second end 44 may also include a guidance device 49.
  • a guidance device 49 is disclosed more fully in U.S. Patent No. 5,810,841, and is hereby incorporated by reference.
  • a detectable signal 55 is emitted from the guidance device 49 on the stylet 37.
  • the detectable signal 55 may be a sound or may be visible light.
  • Figure 3 shows a core collector 58 according to the present invention.
  • the core collector 58 has a first end 61 and a second end 64.
  • the core collector 58 has an axial cavity 67 extending between the first and second ends 61, 64 of the core collector 58.
  • Figure 4 shows a cross-sectioned view of the first end 61 of the core collector 58. Proximate to the first end 61 of the core collector 58 are one or more teeth 70 extending from the core collector 58 into the axial cavity 67.
  • the second end 64 of the core collector 58 includes a haft 73, and also includes a device for connecting 76 the core collector, which may be similar to the mating apparatus to the pin lock connector, described above.
  • Figure 5 shows a sample ejector 79 having a blunt end 82 and a handle end 85.
  • Figure 6 shows a cannula liner 88.
  • the cannula liner 88 is a tubular instrument having an outside diameter 91 slightly smaller than the diameter 94 of the axial channel 34 in the cannula 10.
  • the liner 88 may be provided with a fitting 97 for attaching a syringe for injecting filler material, such as bone cement.
  • the fitting 97 may be a conical fitting with a Luer taper, such as that described in ISO 594-2, first edition 1991- 05-01, published by the International Organization for Standardization .
  • Figures 7A and 7B show steps of a method according to the present invention.
  • an assembly is formed (step 200) by providing a stylet and a cannula similar to those described above, and inserting the stylet into the axial channel of the cannula so the sharpened point of the stylet is proximate to the first end of the cannula.
  • the stylet may have a guidance device similar to that described above .
  • the sharpened point may extend from the cannula depending on the particular shape of the stylet and the cannula, as well as the particular procedure being performed with the stylet and cannula.
  • the stylet is then connected to the cannula via the apparatus for connecting the cannula mating with the device for connecting the stylet .
  • Figure 8 shows the stylet inserted in the cannula.
  • the stylet and cannula assembly is inserted (step 203) into the patient until the first end of the cannula is proximate to the bone to be sampled.
  • the stylet cuts soft tissue surrounding the bone to be sampled, and guides the cannula through the soft tissue in order to place the first end of the cannula proximate to the bone at a sample location where the sample is to be taken.
  • the stylet includes the guidance device, the stylet is inserted at an angle and at a location signified by a guidance beam.
  • the stylet is disconnected (step 206) from the cannula and the cannula is twisted (step 209) via the handle so the helical rib engages the bone, and part of the threaded section is screwed into the bone.
  • the stylet is removed (step 212) from the cannula.
  • the core collector is provided and inserted (step 215) into the channel of the cannula so the first end of the core collector is proximate to the bone.
  • Figure 9 shows the core collector inserted in the cannula.
  • the apparatus for connecting the cannula is connected to the device for connecting the core collector.
  • the cannula is again twisted (step 218) via the handle to further screw the threaded section of the cannula into the bone and to embed the core collector into the bone.
  • the core collector is disconnected from the cannula and pulled out of the bone (step 221) via the haft.
  • the teeth of the core collector engage the bone specimen residing in the axial cavity of the core collector, and prevent the bone specimen from being left in the patient .
  • the core collector, with the bone specimen therein, is removed from the cannula by further pulling on the haft.
  • the blunt end of the sample ejector is then inserted into the axial cavity of the core collector, as shown in Figure 10. By pushing on the handle end of the sample ejector, the blunt end is forced from the first end of the core collector toward the second end of the core collector in order to eject (step 224) the bone sample from the core collector.
  • a cannula liner may be inserted (step 227) into the cannula, and bone cement may be injected through the liner to fill the section of bone where the bone sample was removed.
  • the liner prevents the bone cement from contacting the cannula and hardening on the cannula. If the bone cement hardens in the liner, the liner can be removed and replaced with another liner without disturbing the cannula.
  • the cannula is removed (step 230) from the patient.
  • pituitary forceps 100 shown in Figure 11 are used in lieu of the core collector 58.
  • the cannula 10 is unscrewed from the bone and the first end 13 is left proximate to the bone.
  • Pituitary forceps 100 are inserted through the axial channel 34 of the cannula 10 so the jaws 103 of the pituitary forceps 100 are proximate to the bone.
  • the forceps 100 are manipulated by moving the finger rings 106 relative to each other until the bone sample is grasped by the jaws 103.
  • Figure 12 shows the pituitary forceps 100 inserted in the cannula 10.
  • the pituitary forceps 100 are then removed from the cannula 10, with the bone sample in the jaws 103.
  • the method then continues as described above by inserting the cannula liner 88 and filing the bone with bone cement .
  • the instruments described above can also be used for other procedures, such as cementoplasty of bones or a venogram.
  • the core collector 58 is not used.
  • bone cement has a relatively rapid polymerization time and high viscosity. Therefore, in performing a method according to the present invention, it is preferable to inject bone cement using syringes having a small capacity, for example, a capacity of from 1 to 3 cubic centimeters.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un dispositif d'échantillonnage. Ce dispositif comprend une canule (10) avec une première extrémité (13) et une deuxième extrémité (25). La première extrémité (13) présente une pointe chanfreinée (22) et une section filetée (16) avec une nervure (19) hélicoïdale se projetant. La deuxième extrémité (25) comprend une poignée (28). La canule (10) comporte, en outre, un canal axial (34) s'étendant entre les première et deuxième extrémités. Le canal axial est configuré pour recevoir plusieurs dispositifs médicaux comprenant un canal axial (34), un stylet (37) avec une pointe aiguisée (43) et un collecteur (58) dans une procédure de biopsie. Ce collecteur (58) présente une cavité axiale (67) s'étendant entre une première extrémité (61) et une deuxième extrémité (64) du collecteur (58). La première extrémité (61) du collecteur (58) comprend une ou plusieurs dents (70) s'étendant dans la cavité axiale (67). La deuxième extrémité (64) du collecteur comprend un manche (73) et un dispositif de connecteur (76) pour connecter le collecteur (58) à la canule (10).
PCT/US2000/002302 1999-01-28 2000-01-28 Dispositif d'echantillonnage et procede d'extraction d'un echantillon WO2000044286A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU35849/00A AU3584900A (en) 1999-01-28 2000-01-28 Sampling device and method of retrieving a sample
CA002360529A CA2360529A1 (fr) 1999-01-28 2000-01-28 Dispositif d'echantillonnage et procede d'extraction d'un echantillon
EP00914465A EP1152695A4 (fr) 1999-01-28 2000-01-28 Dispositif d'echantillonnage et procede d'extraction d'un echantillon
JP2000595593A JP2002535064A (ja) 1999-01-28 2000-01-28 サンプルを回収するためのサンプリング装置とその方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11761699P 1999-01-28 1999-01-28
US60/117,616 1999-01-28

Publications (2)

Publication Number Publication Date
WO2000044286A1 true WO2000044286A1 (fr) 2000-08-03
WO2000044286A9 WO2000044286A9 (fr) 2001-09-13

Family

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PCT/US2000/002302 WO2000044286A1 (fr) 1999-01-28 2000-01-28 Dispositif d'echantillonnage et procede d'extraction d'un echantillon

Country Status (5)

Country Link
US (1) US6264618B1 (fr)
EP (1) EP1152695A4 (fr)
JP (1) JP2002535064A (fr)
CA (1) CA2360529A1 (fr)
WO (1) WO2000044286A1 (fr)

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US9924966B2 (en) 2008-04-23 2018-03-27 Atricure, Inc. Articulating cannula access device
US10820913B2 (en) 2013-03-15 2020-11-03 Teleflex Life Sciences Limited Intraosseous device handles, systems, and methods

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9924966B2 (en) 2008-04-23 2018-03-27 Atricure, Inc. Articulating cannula access device
WO2009152173A1 (fr) 2008-06-12 2009-12-17 Ncontact Surgical, Inc. Canule de dissection et procédés d’utilisation de celle-ci
EP2303154A1 (fr) * 2008-06-12 2011-04-06 Ncontact Surgical, Inc. Canule de dissection et procédés d utilisation de celle-ci
EP2303154A4 (fr) * 2008-06-12 2014-04-09 Ncontact Surgical Inc Canule de dissection et procédés d utilisation de celle-ci
US9931132B2 (en) 2008-06-12 2018-04-03 Atricure, Inc. Dissecting cannula and methods of use thereof
US10820913B2 (en) 2013-03-15 2020-11-03 Teleflex Life Sciences Limited Intraosseous device handles, systems, and methods

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Publication number Publication date
EP1152695A4 (fr) 2002-04-03
JP2002535064A (ja) 2002-10-22
CA2360529A1 (fr) 2000-08-03
US6264618B1 (en) 2001-07-24
EP1152695A1 (fr) 2001-11-14
WO2000044286A9 (fr) 2001-09-13

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