WO2000015187A1 - Creatine et/ou derives de creatine utilises comme preparations cosmetiques contenant des agents de maintien d'humidification - Google Patents

Creatine et/ou derives de creatine utilises comme preparations cosmetiques contenant des agents de maintien d'humidification Download PDF

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Publication number
WO2000015187A1
WO2000015187A1 PCT/EP1999/006670 EP9906670W WO0015187A1 WO 2000015187 A1 WO2000015187 A1 WO 2000015187A1 EP 9906670 W EP9906670 W EP 9906670W WO 0015187 A1 WO0015187 A1 WO 0015187A1
Authority
WO
WIPO (PCT)
Prior art keywords
creatine
preparation according
preparation
moisturizers
derivatives
Prior art date
Application number
PCT/EP1999/006670
Other languages
German (de)
English (en)
Inventor
Christian Gloxhuber
Bernd Mertschenk
Original Assignee
Skw Trostberg Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skw Trostberg Aktiengesellschaft filed Critical Skw Trostberg Aktiengesellschaft
Priority to GB0108722A priority Critical patent/GB2357970A/en
Priority to JP2000569772A priority patent/JP2002524486A/ja
Publication of WO2000015187A1 publication Critical patent/WO2000015187A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin

Definitions

  • the present invention relates to the use of creatine and / or creatine derivatives as moisturizers (moisturizers) in cosmetic preparations.
  • Preparations in cream, gel or liquid form which can be used topically for cosmetic purposes, but also orally and then systemically, contain in most cases moisturizers, the so-called moisturizers.
  • moisturizers the so-called moisturizers.
  • humectants also contribute to a certain sense of wellbeing due to the cooling effect that the various cream and gel preparations emit when they are used.
  • the aim of most cosmetic preparations is to have a positive influence on the condition and appearance of the skin.
  • the condition and appearance of the skin are strongly influenced by aging processes.
  • the colloidal state of the protein body for example of collagen
  • changes in such a way that the ability to bind water decreases and the tissue turgor is reduced.
  • atrophic changes which manifests itself in particular in an increased formation of wrinkles and an increased dryness in particular of the upper skin layers, such as the stratum corneum.
  • the increased symptoms associated with these changes such as Dandruff formation, overall lead to a deteriorated appearance of the skin surface.
  • the skin surface is not only changed by aging processes, but also by a number of external influences. So generally cause environmental influences and the weather, but also extreme washing and degreasing of the skin, such as. B. the frequent use of solvents, increased drying of the skin with cracking and flaking. Age-related changes in the skin caused by external influences can add up.
  • the skin In order to counteract these processes that take place on the surface of the skin, the skin naturally has mechanisms that are called natural moisturizing factors.
  • natural moisturizing factors are urea and certain amino acids such as glycine and arginine, which are found naturally on the surface of the skin.
  • moisturizers These naturally occurring substances are supported in modern skin care products - as already mentioned - by the so-called moisturizers.
  • These partially synthetic humectants such as polyols, glycerol, sorbitol, ethoxylated phenols and hydrolyzed proteins, can favorably influence age-related and / or skin roughness due to external influences in the sense that the skin obtains a smoother and smoother surface.
  • a disadvantage of numerous synthetic humectants is their lack of stability, especially over long periods, which leads to the breaking of the emulsions, particularly at extreme temperatures, which has a particularly negative effect on cream-like O / W emulsions.
  • the invention is based on the object of providing a moisturizer for cosmetic preparations which ensures stable preparations, is of natural origin or identical to nature, is also easily accessible and, on account of its composition, does not allow any adverse health effects to be expected.
  • Creatine is a natural compound known as energy storage, especially in muscle tissue, which is non-toxic, is catabolized by the kidneys to urinate creatinine, and is also very well tolerated locally, as experimental studies have shown. Creatine is also known to be able to bind 23 ml of water per gram (cf. Neumann: Creatinabol study).
  • the creatine monohydrate has proven to be particularly suitable in the sense of the present invention and is therefore preferred; but also creatine derivatives, for example in salt form, such as the preferred creatine ascorbate, are very suitable. All suitable creatine derivatives can also be used as mixtures with one another, however also together with other suitable humectants, such as the known natural "moisturizing" factors.
  • creatine derivatives
  • humectants in cosmetic preparations has also proven to be particularly advantageous because, with the suitable creatine compounds, additives can be achieved in part but also synergistically.
  • the invention provides for the creatine and / or its suitable derivatives to be used preferably in creams such as day and night creams, gel-like or liquid preparations, the latter being particularly preferably facial toners, lotions and suspensions.
  • the creatine and / or creatine derivative can also be packaged in liposomes in these and the other preparation forms. This form is preferred if reactions with other components of the preparation are to be avoided.
  • the creatine component (s) according to the invention are preferably used in amounts of 0.5 to 10% by weight, particularly preferably in an amount of 1 to 5% by weight, based in each case on the Overall preparation.
  • the invention is also suitable for oral administration of the preparations containing creatine.
  • the preferred preparation forms which have no other humectants, such as powders, dragees, tablets, troches, capsules, liposomes or liquids, should allow the creatine component to be taken up in an amount which does not exceed a daily dose of 10 g; a daily dose of approx. 4 to 6 g is recommended.
  • creatine components are used in preparations for the outer or inner Used in combination with other physiologically active ingredients.
  • Antioxidants such as ascorbic acid, vitamins such as ⁇ -tocopherol acetate, trace elements and / or sunscreens are preferred.
  • creatine and / or its derivatives according to the invention showed that when the corresponding cosmetic preparations are taken orally, water is stored within the body, but especially in the deeper layers of the skin, as a result of which particularly existing wrinkles can be smoothed and new wrinkle formation is prevented can be.
  • the creatine-containing preparations according to the invention are used locally and mostly superficially, the main phenomenon of dry skin, the skin flaking, is suppressed and the superficial formation of wrinkles is avoided.
  • the correspondingly formulated formulations containing creatine above all improve the elastic properties, in particular of stressed skin, sustainably, which makes them suitable for numerous cosmetic applications which can also go beyond the traditional fields of skin cosmetics, for example in shampoos, hair and mouth and gargling, lipsticks, make-up formulations, hand and foot baths as well as masking creams etc.
  • Skin care product based on an O / W (oil-in-water) cream.

Abstract

L'invention concerne une préparation cosmétique contenant comme agents de maintien d'humidification, de la créatine et/ou des dérivés de créatine.
PCT/EP1999/006670 1998-09-10 1999-09-09 Creatine et/ou derives de creatine utilises comme preparations cosmetiques contenant des agents de maintien d'humidification WO2000015187A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB0108722A GB2357970A (en) 1998-09-10 1999-09-09 Creatine and/or creatine derivatives used as cosmetic preparations containing moisturizers
JP2000569772A JP2002524486A (ja) 1998-09-10 1999-09-09 保湿剤としてのクレアチン及び／又はクレアチン誘導体を含有する化粧用組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19841385.8 1998-09-10
DE1998141385 DE19841385A1 (de) 1998-09-10 1998-09-10 Verwendung von Kreatin und/oder Kreatin-derivaten als Feuchthaltemittel in kosmetischen Zubereitungen

Publications (1)

Publication Number Publication Date
WO2000015187A1 true WO2000015187A1 (fr) 2000-03-23

Family

ID=7880498

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/006670 WO2000015187A1 (fr) 1998-09-10 1999-09-09 Creatine et/ou derives de creatine utilises comme preparations cosmetiques contenant des agents de maintien d'humidification

Country Status (4)

Country Link
JP (1) JP2002524486A (fr)
DE (1) DE19841385A1 (fr)
GB (1) GB2357970A (fr)
WO (1) WO2000015187A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001054676A2 (fr) * 2000-01-28 2001-08-02 Degussa Ag Formulations destinees a des etats de deshydratation
DE10119608A1 (de) * 2001-04-21 2002-10-24 Goldschmidt Ag Th Verwendung von Kreatin und/oder Kreatin-Derivaten in Haarbehandlungsmitteln und Haarnachbehandlungsmitteln zum Schutz vor Schäden durch chemische Behandlung und zur Reparatur bereits geschädigter Haare
EP1338269A1 (fr) * 2002-02-15 2003-08-27 Goldschmidt AG Composition pour éclaircir la peau et pour soulager les désordres de pigmentation contenant créatinine et/ou des dérivés de créatinine comme agent actif
EP1535605A1 (fr) * 2003-11-26 2005-06-01 Beiersdorf AG Préparations cosmétiques contenant de la créatine et/ou des dérivés de la créatine et/ou de la créatinine et/ou des dérivés de la créatinine et un épaississant organique.
EP1535604A1 (fr) * 2003-11-26 2005-06-01 Beiersdorf AG Combinaison à base de créatine et/ou de créatinine, de phenoxyethanol et éventuallement de glycérine.
US7186754B2 (en) 1999-06-25 2007-03-06 Avicena Group, Inc. Use of creatine or creatine compounds for skin preservation
EP1328242B2 (fr) † 2001-03-24 2015-07-22 Wella Aktiengesellschaft Utilisation non-therapeutique de la creatine, de la creatinine et/ou du cyclocreatine afin de renforcer les cheveux et d'ameliorer leur structure

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10032964B4 (de) * 2000-07-06 2017-10-12 Beiersdorf Ag Verwendung von Kreatin in kosmetischen oder dermatologischen Zubereitungen
DE10106288A1 (de) * 2001-02-02 2002-09-05 Coty Bv Revitalisierender Wirkkomplex für die Haut
DE10133198A1 (de) * 2001-07-07 2003-01-23 Beiersdorf Ag Kreatin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
DE10136076A1 (de) * 2001-07-25 2003-02-13 Beiersdorf Ag Verwendung von Kreatinin und/oder Kreatininderivaten in kosmetischen oder dermatologischen Zubereitungen
DE10136077A1 (de) * 2001-07-25 2003-02-13 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einer Kombination von Kreatinin und/oder Kreatininderivaten mit Kreatin und/oder seinen Derivaten
DE10301632A1 (de) * 2003-01-17 2004-07-29 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Kreatin, Kreatinin und/oder seinen Derivaten in Kombination mit Sojabohnenkeimextrakten
DE102004009962A1 (de) * 2004-03-01 2005-09-22 Degussa Ag Verwendung von Guanidin-Verbindungen als physiologisches Stärkungsmittel in Form von Nahrungsergänzungsmitteln, Futtermittelzusätzen, in kosmetischen Zubereitungen und als Pflanzenstärkungsmittel
JP5756614B2 (ja) * 2010-11-02 2015-07-29 花王株式会社 オートインデューサー−２阻害剤、並びに齲蝕病の予防及び／又は治療剤

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US5091171A (en) * 1986-12-23 1992-02-25 Yu Ruey J Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use
FR2725896A1 (fr) * 1994-10-19 1996-04-26 Sederma Sa Nouvelles compositions cosmetiques ou dermopharmaceutiques
JPH09202710A (ja) * 1995-11-20 1997-08-05 Kao Corp しわ改善剤
US5939078A (en) * 1995-11-20 1999-08-17 Kao Corporation Wrinkle-care product

Patent Citations (6)

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US5091171A (en) * 1986-12-23 1992-02-25 Yu Ruey J Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use
US5091171B1 (en) * 1986-12-23 1995-09-26 Ruey J Yu Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use
US5091171B2 (en) * 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
FR2725896A1 (fr) * 1994-10-19 1996-04-26 Sederma Sa Nouvelles compositions cosmetiques ou dermopharmaceutiques
JPH09202710A (ja) * 1995-11-20 1997-08-05 Kao Corp しわ改善剤
US5939078A (en) * 1995-11-20 1999-08-17 Kao Corporation Wrinkle-care product

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Title
K. SAKAMOTO: "The development of two new moisturizing ingredients", COSMETICS & TOILETRIES, vol. 99, no. 3, 1984, pages 109 - 117, XP000571951 *
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 12 25 December 1997 (1997-12-25) *

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7186754B2 (en) 1999-06-25 2007-03-06 Avicena Group, Inc. Use of creatine or creatine compounds for skin preservation
WO2001054676A2 (fr) * 2000-01-28 2001-08-02 Degussa Ag Formulations destinees a des etats de deshydratation
WO2001054676A3 (fr) * 2000-01-28 2002-05-16 Sueddeutsche Kalkstickstoff Formulations destinees a des etats de deshydratation
EP1328242B2 (fr) † 2001-03-24 2015-07-22 Wella Aktiengesellschaft Utilisation non-therapeutique de la creatine, de la creatinine et/ou du cyclocreatine afin de renforcer les cheveux et d'ameliorer leur structure
DE10119608A1 (de) * 2001-04-21 2002-10-24 Goldschmidt Ag Th Verwendung von Kreatin und/oder Kreatin-Derivaten in Haarbehandlungsmitteln und Haarnachbehandlungsmitteln zum Schutz vor Schäden durch chemische Behandlung und zur Reparatur bereits geschädigter Haare
EP1338269A1 (fr) * 2002-02-15 2003-08-27 Goldschmidt AG Composition pour éclaircir la peau et pour soulager les désordres de pigmentation contenant créatinine et/ou des dérivés de créatinine comme agent actif
AU2003200465B2 (en) * 2002-02-15 2007-09-06 Evonik Goldschmidt Gmbh Compositions for Skin Lightening and Toning Down Pigment Disorders, Comprising Creatinine and/or Creatinine Derivatives as Active Substances
EP1535605A1 (fr) * 2003-11-26 2005-06-01 Beiersdorf AG Préparations cosmétiques contenant de la créatine et/ou des dérivés de la créatine et/ou de la créatinine et/ou des dérivés de la créatinine et un épaississant organique.
EP1535604A1 (fr) * 2003-11-26 2005-06-01 Beiersdorf AG Combinaison à base de créatine et/ou de créatinine, de phenoxyethanol et éventuallement de glycérine.
EP2796136A1 (fr) * 2003-11-26 2014-10-29 Beiersdorf AG Préparations cosmétiques ayant une teneur de créatine et/ou des dérivés de créatine et des épaississants organiques
US10682534B2 (en) 2003-11-26 2020-06-16 Beiersdorf, Ag Cosmetic preparations containing creatine and/or creatinine and organic thickeners
US10888719B2 (en) 2003-11-26 2021-01-12 Beiersdorf Ag Active substance combination of creatine and/or creatinine and phenoxyethanol

Also Published As

Publication number Publication date
GB0108722D0 (en) 2001-05-30
DE19841385A1 (de) 2000-03-16
JP2002524486A (ja) 2002-08-06
GB2357970A (en) 2001-07-11

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