WO1999007307A1 - Prothese pour implantation et procede de fabrication - Google Patents

Prothese pour implantation et procede de fabrication Download PDF

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Publication number
WO1999007307A1
WO1999007307A1 PCT/RU1998/000260 RU9800260W WO9907307A1 WO 1999007307 A1 WO1999007307 A1 WO 1999007307A1 RU 9800260 W RU9800260 W RU 9800260W WO 9907307 A1 WO9907307 A1 WO 9907307A1
Authority
WO
WIPO (PCT)
Prior art keywords
prosthesis
shape
film
tetrafluoroethylene
matrix
Prior art date
Application number
PCT/RU1998/000260
Other languages
English (en)
Russian (ru)
Inventor
Valery Evgenievich Diyakov
Arkady Konstantinovich Pugachev
Andrei Viktorovich Kryzhanovsky
Igor Valerievich Mikhailov
Alexei Valerievich Gusinsky
Lev Valerievich Lebedev
Original Assignee
Zakrytoe Aktsionernoe Obschestvo 'nauchno-Proizvodstvenny Komplex 'ekoflon'
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zakrytoe Aktsionernoe Obschestvo 'nauchno-Proizvodstvenny Komplex 'ekoflon' filed Critical Zakrytoe Aktsionernoe Obschestvo 'nauchno-Proizvodstvenny Komplex 'ekoflon'
Priority to AU88929/98A priority Critical patent/AU8892998A/en
Publication of WO1999007307A1 publication Critical patent/WO1999007307A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
    • B29C55/005—Shaping by stretching, e.g. drawing through a die; Apparatus therefor characterised by the choice of materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
    • B29C53/56—Winding and joining, e.g. winding spirally
    • B29C53/58—Winding and joining, e.g. winding spirally helically
    • B29C53/581—Winding and joining, e.g. winding spirally helically using sheets or strips consisting principally of plastics material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2027/00—Use of polyvinylhalogenides or derivatives thereof as moulding material
    • B29K2027/12—Use of polyvinylhalogenides or derivatives thereof as moulding material containing fluorine
    • B29K2027/18—PTFE, i.e. polytetrafluorethene, e.g. ePTFE, i.e. expanded polytetrafluorethene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses

Definitions

  • the invention is subject to medical equipment, and the name implants used to replace in the body of the unit or to process the process of processing Iz ⁇ b ⁇ e ⁇ enie m ⁇ zhe ⁇ by ⁇ is ⁇ lz ⁇ van ⁇ in ⁇ aches ⁇ ve ⁇ eza v ⁇ vnu ⁇ is ⁇ sudis ⁇ y ⁇ i ⁇ u ⁇ gii, ⁇ i ⁇ u ⁇ gii ⁇ v e ⁇ s ⁇ ase ⁇ e ⁇ ny ⁇ ⁇ gan ⁇ v, ⁇ i ⁇ u ⁇ giches ⁇ y ⁇ n ⁇ l ⁇ gii, gas ⁇ en ⁇ e ⁇ l ⁇ gii, u ⁇ l ⁇ gii, gine ⁇ l ⁇ gii, ney ⁇ i ⁇ u ⁇ gii and ⁇ ulm ⁇ n ⁇ l ⁇ gii and ⁇ a ⁇ zhe for e ⁇ s ⁇ aana ⁇ miches ⁇ g ⁇ is ⁇ lz ⁇ vaniya.
  • P ⁇ i is ⁇ lz ⁇ vanii ⁇ ls ⁇ s ⁇ enny ⁇ ⁇ ez ⁇ v ⁇ ven ⁇ sny ⁇ s ⁇ sud ⁇ v nablyudae ⁇ sya ⁇ yavlenie sleduyuschi ⁇ nezhela ⁇ elny ⁇ phenomena ⁇ le ⁇ chnye elemen ⁇ y and s ⁇ edini ⁇ eln ⁇ annye v ⁇ l ⁇ na not m ⁇ gu ⁇ glub ⁇ ⁇ ni ⁇ nu ⁇ in s ⁇ u ⁇ u ⁇ u in sleds ⁇ vie ⁇ il ⁇ b ⁇ azn ⁇ g ⁇ e ⁇ e ⁇ a labi ⁇ in ⁇ ny ⁇ ⁇ .
  • the result is a reduction in the “implantation” of the prosthesis, difficulty or loss of exchange with the body of the cell and elements of connecting fabric, deeply absorbed in the structure, due to their catabolism and destruction, which recalls the process of unloading.
  • a widespread vessel is known to have been delivered from an empty vessel made of an emergency, in the form of a cylindrical tube, the thickness is 0.3%.
  • a small restriction on the thickness is set by the manufacturing technology of the appliances. (European Patent ⁇ ° 0293090 ⁇ 2, ⁇ 61L 27/00, 1988).
  • Izves ⁇ en being naib ⁇ lee bliz ⁇ im ⁇ iz ⁇ b ⁇ e ⁇ eniyu, s ⁇ s ⁇ b izg ⁇ vleniya ⁇ l ⁇ g ⁇ ⁇ eza of ⁇ li ⁇ e ⁇ a ⁇ e ⁇ ilena, ⁇ ⁇ mu ⁇ izv ⁇ dya ⁇ mixing is ⁇ dn ⁇ g ⁇ ma ⁇ e ⁇ iala as ⁇ sh ⁇ a s ⁇ binder with ⁇ lucheniem ⁇ as ⁇ y, ⁇ ess ⁇ vanie ⁇ as ⁇ y, e ⁇ s ⁇ uziyu with ⁇ lucheniem ⁇ iln ⁇ y zag ⁇ v ⁇ i, removal svyazuyuscheg ⁇ , ⁇ as ⁇ yazhenie zag ⁇ v ⁇ i for ⁇ lucheniya ne ⁇ b ⁇ dim ⁇ y ⁇ is ⁇ s ⁇ i ma ⁇ e ⁇ iala,
  • PFFE hexafluoride
  • PFC hexafluoride
  • a compound with a non-permeable voltage do not ⁇ zavisim ⁇ s ⁇ i ⁇ form ⁇ ezi ⁇ vaniya ⁇ lschina ⁇ lime ⁇ n ⁇ g ⁇ ma ⁇ e- ⁇ iala len ⁇ y not less than 0.005mm, ug ⁇ l nam ⁇ i len ⁇ y b ⁇ ly ⁇ e 0 and less than or ⁇ aven 90 g ⁇ adus ⁇ v, shi ⁇ ina ⁇ e ⁇ e ⁇ y ⁇ iya vi ⁇ v nam ⁇ i s ⁇ s ⁇ avlyae ⁇ ⁇ d ⁇ 0.2 to 5 mm, and the pitch nam ⁇ i ⁇ aven or meny ⁇ e shi ⁇ iny len ⁇ y.
  • the forming body of the heart is performed, preferably, in the form of a body of growth or in the form of control with branches or branches, for example, bifurcation.
  • the task is achieved if the tape spacing is equal to or greater than the belt, or more or less than 90 or less.
  • thermopile 100 hexafluorophenylene, or a compound of thermopile and vinyl oxide, or metal, or carbon fiber.
  • the objective of the invention is, in part, to expand its technological capabilities and increase its productivity.
  • Body shaping which consists of at least
  • One layer is available through the destruction of the material, which is optionally available as a tape; Received in the process of extrusion, a filial preparation of the process is processed to receive a layer of the material
  • 135 parts of the unit is free from 25 to 94%, specific unit of the unit is 0.1 to 9.0 ⁇ m 2 / ⁇ m 3 , with an average distance between the unit of 50 6
  • ⁇ 0.4 to 30 ⁇ m either: a volume share of the free space of 1 to 35%, a specific volume of the free space of 0.5 to 20
  • the final processing process is carried out at temperatures higher than the melting point of the furnace to ensure that the welding process is not carried out for 2 minutes.
  • FIG. 1 depicts a single-sided hollow cylindrical method, which is made from a ribbon wound on a variable core with different angles of delivery;
  • FIG. 2 illustrates a multi-layered tap from a tape with a step of a coiling angle equal to the width of the tape;
  • Fig. 3 depicts a multi-part return from a tape, on the other hand, with the interruption of the supply chain
  • Fig. 4 illustrates a multi-cylinder cylinder with 170 quick-feed tapes
  • Figure 5 depicts a multi-step method, just the second step is to take a larger width of the tape
  • ⁇ ig. 6 hereby shews tapes for a physical body of the core; 175 Fig. 7 illustrates a two-layer method with a high utilization of the internal layer and a low level of use of the outdoor;
  • Figure 8 depicts an amendment to the external outdoor environment
  • Fig. 9 depicts a process equipped with an internal metal coil
  • Fig. 10 contains a gazette of the patient and the patient with a high quality of health and equipment, and the patient was taken away from the patient.
  • interconnected matrices namely, the matrix of the polymer in the form of nodes connected by fibers, and the matrix
  • the elements are simply connected to the circuit, in particular the number of units, the unit and the unit is not connected to a unit.
  • a corner of the tape ⁇ which turns on the body 2 or damaged by 2, 3 or less 0 or less 0 or less and 0 or less
  • the step of setting is equal to the width of the tape.
  • the high biological sensitivity of the device is ensured by the absence of deep layers of the battery, which are designed to protect people from fatigue.
  • the greater depth of the cell and connecting elements in the wall of the device allows them to actively participate in the process of exchange, ensuring
  • VAS emergency vessel
  • Implantation involves filling the product matrix with the elements of the used tissue from the country
  • FIG. 245 The multi-layered version of FIG. 5, which is 7, in quick-set second layer 8, is carried out with the tape at a step that raises its width and may not be used at all prolonged term of action when filling up the area with bactericidal substances.
  • the specific velocity of the matrix / ⁇ m 2 / ⁇ m 3 / is the reduction in the volume of the matrix to its volume.
  • Fig. 7 is a multi-part version of 10, the outer layer 11 is made from a material that has a volumetric length
  • the random drive shown in FIG. 8, is equipped with a screw that is applied to the outer layer of harness 14 from a polystyrene or a compound of heat and ethylene.
  • 295 hexadecimal may be used when unplugging with the condition of cutting off the light in the place of automatic bending or compression of the machine.
  • Fig. 9 is a multi-step version of 15, equipped with a screw applied between the outside and the inside.
  • 300 harness 16 of the metal are used in endovascular interventions.
  • the manufacture of implantable implants is carried out in the following manner. 12
  • PFE is mixed with liquid hydrocarbon lubricant, for example, vaseline oil in a hermetic
  • the harness burns out for the production of a layer of material with a thickness of 0.03 to 0.2 mm.
  • the grease is removed.
  • the film is allowed to dry to remove the residues of the solvent.
  • the initial size is one of the known methods with a speed of 5%> in the sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C, followed by a temperature of 330-350 ° C for 2-5 minutes. Received by such a material possesses the following standard (volumetric)
  • the material is sold on a basic basis.
  • the initial size is sold at a rate of 5% per sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C with a subsequent temperature of 330-350 ° C for 2-5 minutes.
  • the material possesses the following standard (volumetric) parameters:
  • a single or double extended material is cut onto tapes and wound onto reels.
  • the body of the vessel is provided by the last purchase of tapes for the rotating core, the size of the cable and the connection are replaced.
  • the parameters of the wiring are chosen as well: the angle and the step of the wiring, the strength of the wiring, the wiring is silent.
  • the formed raw batch, together with the center, is located in the tank, where it is cooked for 2-30 minutes at the temperature above the tank for melting.
  • you will be able to weld the tape inside a single layer and to weld a layer through the manufacture of a large number of goods.
  • the tightness of the contact between the welded parts is ensured in 1
  • the following process is carried out at a temperature of 20 -160 ° C.
  • EXAMPLE 1 Inventory consisting of 80> 4D for GES 14906 brand L and 20> for hydrocarbon grease, for which 4000 g are used for 4
  • such a film supports the processing of the film and the temperature of the film
  • the film samples have the characteristics shown in Table 1.
  • the resulting product may be used for implantation in the form of payments or chemical membranes.
  • Example 2 Received sample 1a as agreed 1.
  • 395 offers an exhaust hood in the opposite direction of 100, 200 and 300%, using one of the known methods. In general, the cost of the original film increases in 4, 6 and 8 times. Received after 16
  • Hoods from the film support the temperature control at a temperature of 340 ° C for 5 minutes in a fixed state. Chilled
  • the 400 room temperature switch sets free the clamps and transfers them to the bobbin after turning them round.
  • samples of a stretched film have the characteristics shown in Table 2.
  • Samples 2a, 26, and 2b may be used for implantation or implantation.
  • the samples of the obtained film have the characteristics shown in Table 3.
  • the samples for and 36 may be used for implantation in the form of a payment or a trial.
  • EXAMPLE 4 Sample 16 is adopted as an example 1. The sample is exhausted at 100, 200 and 300%, using one of the known sorts. Our area 99/07307 ⁇ / ⁇ 8 / 00260
  • samples of the obtained film have the following specifications shown in Table 4.
  • Samples 4a and 46 can be used for implantation or as a means of implantation.
  • EXAMPLE 5 A film sample is received 16 according to Example 1. The film obtained is cut into a width of 10 mm and wound onto a rotating metal core of 10 mm
  • Integrity was provided only at a small voltage from the anastomosis line (0.5 cm) and the tip was smooth, smooth
  • mikroskopii non-diversion is provided by a young connecting fabric. Integrable in the area of the anastomoses is provided by the young differentiating connecting tissue, which is fastened
  • a combination of the recorded properties allows the use of a temporary shunt when a vessel is used, and a temporary shunt for hemodialysis is used.
  • Example 6 Receive the product according to Example 5 and forward its exhaust by 300% with the next process in the absence of temperature of 340 minutes.
  • Integrity is smooth, shiny, without tromboticheskih taxes, is provided to all the internal part of the process and soldered to the wall.
  • the tank is intact and the external capsule is provided by a young, differentiated connecting tissue, which impedes
  • the described properties make it possible to use the product as a part of the purchase of portable lymphatic tests or endoscopic devices.
  • Example 7 According to Example 5 of a sample of a film 2a, a product 7a is produced. A sample of the product was examined using an electronic microscope and will allow the analysis of a simple structure on an automatic analysis of devices (TI). A photograph was taken of a cross-section of the product and its stereologic characteristics,
  • EXAMPLE 8 A sample of film 1a is adopted as per Example 1.
  • the film received is cut into a width of 12 mm and rewound in a layer of 8 mm across the rotating metal core with a width of 10 mm and is wider.
  • the angle of purchase is 60 °.
  • the rotational speed of the core is 60 minutes "1.
  • Each subsequent layer is applied at a 90 ° angle to the ratio ⁇
  • the core is mixed with an intentional film and mixed in a furnace heated to a temperature of 355 ° C and kept there for 5 minutes. After cooling, the product is removed from the center.
  • the resulting product may be used when replacing defects in the air conditioner to ensure the safety function.
  • EXAMPLE 10 A film sample 36 is received, cut onto tapes.
  • Example 11 Received a film sample 16 as agreed 1. Received film is cut into a width of 10 mm and wound onto a rotating metal core of 10 mm.
  • the first layer of tape is wound around a tow of polished plastic, received from a traditional medical practice.”
  • the step is 4mm.
  • the core with the intended film is placed in the furnace, heated to a temperature of 340 ° C, and kept there for 7 minutes. After cooling, the product is removed from the center.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Cette invention concerne une prothèse creuse pour implantation qui est faite d'un matériau polymère tel que du polytetrafluoroéthylène (PTFE) ou, encore, des copolymères de tetrafluoroéthylène (TFE) avec de l'hexafluropropylène ou de TFE avec de l'ester de perfluorovinylpropyle, la teneur en comonomère ne dépassant pas 2 %. La structure de cette prothèse se caractérise en ce qu'elle comprend deux matrices reliées et pénétrant l'une dans l'autre. L'une de ces matrices est faite d'un polymère se présentant sous forme de noeuds reliés par des fibrilles, tandis que l'autre matrice forme un espace vide dont les éléments sont reliés en un réseau tridimensionnel. La quantité de noeuds, de fibrilles et d'éléments de l'espace vide n'est pas constante par unité de volume, ces composants se présentant principalement sous forme d'une bande (B) qui est enroulée sur un noyau (N) définissant la forme du corps de la prothèse. La forme, les dimensions et la configuration de ce noyau correspondent à l'organe que l'on souhaite remplacer ou à une partie de celui-ci. Le corps (C) de la prothèse peut en outre comprendre une tresse (T) qui est appliquée en spirale, et qui se compose de polytetrafluoroéthylène, d'un copolymère de tetrafluoroéthylène et d'hexafluoropropylène, d'un copolymère de tetrafluoroéthylène et d'ester de perfluorovinylpropyle, d'un métal ou, encore, d'une fibre de carbone. Cette invention concerne également un procédé de fabrication d'une prothèse en PTFE, lequel comprend les étapes suivantes: mélanger le matériau de départ sous forme de poudre à un agent de liaison de manière à former une pâte; presser cette pâte puis l'extruder de manière à obtenir une ébauche profilée; éliminer l'agent de liaison; puis étirer l'ébauche profilée de manière à obtenir la porosité voulue du matériau formant le corps. Ce procédé se caractérise en ce que l'ébauche profilée est remodelée en une couche de matériau dont l'épaisseur varie de 0,03 à 0,2 mm. L'étirement de la couche de matériau se fait selon un ou deux axes jusqu'à la mise en forme du corps de la prothèse.
PCT/RU1998/000260 1997-08-07 1998-08-07 Prothese pour implantation et procede de fabrication WO1999007307A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU88929/98A AU8892998A (en) 1997-08-07 1998-08-07 Prosthesis for implantation and method for preparing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU97112837 1997-08-07
RU97112837/14A RU2128024C1 (ru) 1997-08-07 1997-08-07 Имплантируемый полый протез и способ его изготовления

Publications (1)

Publication Number Publication Date
WO1999007307A1 true WO1999007307A1 (fr) 1999-02-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU1998/000260 WO1999007307A1 (fr) 1997-08-07 1998-08-07 Prothese pour implantation et procede de fabrication

Country Status (3)

Country Link
AU (1) AU8892998A (fr)
RU (1) RU2128024C1 (fr)
WO (1) WO1999007307A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2429407A (en) * 2005-06-04 2007-02-28 Vascutek Ltd Thin-walled vascular graft
US20090258958A1 (en) * 2007-10-04 2009-10-15 Ford Lawrence A Expandable TFE Copolymers, Methods of Making, and Porous, Expanded Articles Thereof
CN103977457A (zh) * 2014-05-30 2014-08-13 国家纳米科学中心 一种管状组织工程支架及其制备方法
US9644054B2 (en) 2014-12-19 2017-05-09 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same
US9650479B2 (en) 2007-10-04 2017-05-16 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same

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RU2203685C2 (ru) * 2001-06-26 2003-05-10 Закрытое акционерное общество "Научно-производственный комплекс "Экофлон" Имплантат для восстановительной хирургии
RU2207825C1 (ru) * 2002-04-04 2003-07-10 Дьяков Валерий Евгеньевич Имплантируемый полый протез
US20100215643A1 (en) * 2009-02-25 2010-08-26 Orthobond Corp. Anti-infective functionalized surfaces and methods of making same

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SU628911A1 (ru) * 1977-02-08 1978-10-25 Предприятие П/Я Г-4299 Протез кровеносного сосуда и способ его изготовлени
EP0146794A2 (fr) * 1983-12-16 1985-07-03 B. Braun-SSC AG Procédé pour la production d'une artère artificielle
EP0230635A2 (fr) * 1985-12-24 1987-08-05 Sumitomo Electric Industries Limited Prothèse tubulaire ayant une structure composite
WO1987005796A1 (fr) * 1986-03-27 1987-10-08 Advanced Vascular Technologies, Inc. Protheses vasculaires et procede de fabrication
US4713070A (en) * 1978-11-30 1987-12-15 Sumitom Electric Industries, Ltd. Porous structure of polytetrafluoroethylene and process for production thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU628911A1 (ru) * 1977-02-08 1978-10-25 Предприятие П/Я Г-4299 Протез кровеносного сосуда и способ его изготовлени
US4713070A (en) * 1978-11-30 1987-12-15 Sumitom Electric Industries, Ltd. Porous structure of polytetrafluoroethylene and process for production thereof
EP0146794A2 (fr) * 1983-12-16 1985-07-03 B. Braun-SSC AG Procédé pour la production d'une artère artificielle
EP0230635A2 (fr) * 1985-12-24 1987-08-05 Sumitomo Electric Industries Limited Prothèse tubulaire ayant une structure composite
WO1987005796A1 (fr) * 1986-03-27 1987-10-08 Advanced Vascular Technologies, Inc. Protheses vasculaires et procede de fabrication

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2429407A (en) * 2005-06-04 2007-02-28 Vascutek Ltd Thin-walled vascular graft
GB2429407B (en) * 2005-06-04 2009-10-14 Vascutek Ltd Thin-walled vascular graft
US7901446B2 (en) 2005-06-04 2011-03-08 Vascutek Limited Thin-walled vascular graft
US20090258958A1 (en) * 2007-10-04 2009-10-15 Ford Lawrence A Expandable TFE Copolymers, Methods of Making, and Porous, Expanded Articles Thereof
US8911844B2 (en) 2007-10-04 2014-12-16 W. L. Gore & Associates, Inc. Expanded TFE copolymers, method of making and porous, expanded articles thereof
US9040646B2 (en) * 2007-10-04 2015-05-26 W. L. Gore & Associates, Inc. Expandable TFE copolymers, methods of making, and porous, expanded articles thereof
US9193811B2 (en) 2007-10-04 2015-11-24 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, and porous, expanded articles thereof
US9593223B2 (en) 2007-10-04 2017-03-14 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, porous, expanded article thereof
US9650479B2 (en) 2007-10-04 2017-05-16 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same
US9988506B2 (en) 2007-10-04 2018-06-05 W. L. Gore & Associates, Inc. Dense articles formed tetrafluoroethylene core shell copolymers and methods of making the same
CN103977457A (zh) * 2014-05-30 2014-08-13 国家纳米科学中心 一种管状组织工程支架及其制备方法
US9644054B2 (en) 2014-12-19 2017-05-09 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same

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