WO1999007307A1 - Prosthesis for implantation and method for preparing the same - Google Patents

Prosthesis for implantation and method for preparing the same Download PDF

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Publication number
WO1999007307A1
WO1999007307A1 PCT/RU1998/000260 RU9800260W WO9907307A1 WO 1999007307 A1 WO1999007307 A1 WO 1999007307A1 RU 9800260 W RU9800260 W RU 9800260W WO 9907307 A1 WO9907307 A1 WO 9907307A1
Authority
WO
WIPO (PCT)
Prior art keywords
prosthesis
shape
film
tetrafluoroethylene
matrix
Prior art date
Application number
PCT/RU1998/000260
Other languages
French (fr)
Russian (ru)
Inventor
Valery Evgenievich Diyakov
Arkady Konstantinovich Pugachev
Andrei Viktorovich Kryzhanovsky
Igor Valerievich Mikhailov
Alexei Valerievich Gusinsky
Lev Valerievich Lebedev
Original Assignee
Zakrytoe Aktsionernoe Obschestvo 'nauchno-Proizvodstvenny Komplex 'ekoflon'
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zakrytoe Aktsionernoe Obschestvo 'nauchno-Proizvodstvenny Komplex 'ekoflon' filed Critical Zakrytoe Aktsionernoe Obschestvo 'nauchno-Proizvodstvenny Komplex 'ekoflon'
Priority to AU88929/98A priority Critical patent/AU8892998A/en
Publication of WO1999007307A1 publication Critical patent/WO1999007307A1/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C55/00—Shaping by stretching, e.g. drawing through a die; Apparatus therefor
    • B29C55/005—Shaping by stretching, e.g. drawing through a die; Apparatus therefor characterised by the choice of materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C53/00—Shaping by bending, folding, twisting, straightening or flattening; Apparatus therefor
    • B29C53/56—Winding and joining, e.g. winding spirally
    • B29C53/58—Winding and joining, e.g. winding spirally helically
    • B29C53/581—Winding and joining, e.g. winding spirally helically using sheets or strips consisting principally of plastics material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2027/00—Use of polyvinylhalogenides or derivatives thereof as moulding material
    • B29K2027/12—Use of polyvinylhalogenides or derivatives thereof as moulding material containing fluorine
    • B29K2027/18—PTFE, i.e. polytetrafluorethene, e.g. ePTFE, i.e. expanded polytetrafluorethene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses

Definitions

  • the invention is subject to medical equipment, and the name implants used to replace in the body of the unit or to process the process of processing Iz ⁇ b ⁇ e ⁇ enie m ⁇ zhe ⁇ by ⁇ is ⁇ lz ⁇ van ⁇ in ⁇ aches ⁇ ve ⁇ eza v ⁇ vnu ⁇ is ⁇ sudis ⁇ y ⁇ i ⁇ u ⁇ gii, ⁇ i ⁇ u ⁇ gii ⁇ v e ⁇ s ⁇ ase ⁇ e ⁇ ny ⁇ ⁇ gan ⁇ v, ⁇ i ⁇ u ⁇ giches ⁇ y ⁇ n ⁇ l ⁇ gii, gas ⁇ en ⁇ e ⁇ l ⁇ gii, u ⁇ l ⁇ gii, gine ⁇ l ⁇ gii, ney ⁇ i ⁇ u ⁇ gii and ⁇ ulm ⁇ n ⁇ l ⁇ gii and ⁇ a ⁇ zhe for e ⁇ s ⁇ aana ⁇ miches ⁇ g ⁇ is ⁇ lz ⁇ vaniya.
  • P ⁇ i is ⁇ lz ⁇ vanii ⁇ ls ⁇ s ⁇ enny ⁇ ⁇ ez ⁇ v ⁇ ven ⁇ sny ⁇ s ⁇ sud ⁇ v nablyudae ⁇ sya ⁇ yavlenie sleduyuschi ⁇ nezhela ⁇ elny ⁇ phenomena ⁇ le ⁇ chnye elemen ⁇ y and s ⁇ edini ⁇ eln ⁇ annye v ⁇ l ⁇ na not m ⁇ gu ⁇ glub ⁇ ⁇ ni ⁇ nu ⁇ in s ⁇ u ⁇ u ⁇ u in sleds ⁇ vie ⁇ il ⁇ b ⁇ azn ⁇ g ⁇ e ⁇ e ⁇ a labi ⁇ in ⁇ ny ⁇ ⁇ .
  • the result is a reduction in the “implantation” of the prosthesis, difficulty or loss of exchange with the body of the cell and elements of connecting fabric, deeply absorbed in the structure, due to their catabolism and destruction, which recalls the process of unloading.
  • a widespread vessel is known to have been delivered from an empty vessel made of an emergency, in the form of a cylindrical tube, the thickness is 0.3%.
  • a small restriction on the thickness is set by the manufacturing technology of the appliances. (European Patent ⁇ ° 0293090 ⁇ 2, ⁇ 61L 27/00, 1988).
  • Izves ⁇ en being naib ⁇ lee bliz ⁇ im ⁇ iz ⁇ b ⁇ e ⁇ eniyu, s ⁇ s ⁇ b izg ⁇ vleniya ⁇ l ⁇ g ⁇ ⁇ eza of ⁇ li ⁇ e ⁇ a ⁇ e ⁇ ilena, ⁇ ⁇ mu ⁇ izv ⁇ dya ⁇ mixing is ⁇ dn ⁇ g ⁇ ma ⁇ e ⁇ iala as ⁇ sh ⁇ a s ⁇ binder with ⁇ lucheniem ⁇ as ⁇ y, ⁇ ess ⁇ vanie ⁇ as ⁇ y, e ⁇ s ⁇ uziyu with ⁇ lucheniem ⁇ iln ⁇ y zag ⁇ v ⁇ i, removal svyazuyuscheg ⁇ , ⁇ as ⁇ yazhenie zag ⁇ v ⁇ i for ⁇ lucheniya ne ⁇ b ⁇ dim ⁇ y ⁇ is ⁇ s ⁇ i ma ⁇ e ⁇ iala,
  • PFFE hexafluoride
  • PFC hexafluoride
  • a compound with a non-permeable voltage do not ⁇ zavisim ⁇ s ⁇ i ⁇ form ⁇ ezi ⁇ vaniya ⁇ lschina ⁇ lime ⁇ n ⁇ g ⁇ ma ⁇ e- ⁇ iala len ⁇ y not less than 0.005mm, ug ⁇ l nam ⁇ i len ⁇ y b ⁇ ly ⁇ e 0 and less than or ⁇ aven 90 g ⁇ adus ⁇ v, shi ⁇ ina ⁇ e ⁇ e ⁇ y ⁇ iya vi ⁇ v nam ⁇ i s ⁇ s ⁇ avlyae ⁇ ⁇ d ⁇ 0.2 to 5 mm, and the pitch nam ⁇ i ⁇ aven or meny ⁇ e shi ⁇ iny len ⁇ y.
  • the forming body of the heart is performed, preferably, in the form of a body of growth or in the form of control with branches or branches, for example, bifurcation.
  • the task is achieved if the tape spacing is equal to or greater than the belt, or more or less than 90 or less.
  • thermopile 100 hexafluorophenylene, or a compound of thermopile and vinyl oxide, or metal, or carbon fiber.
  • the objective of the invention is, in part, to expand its technological capabilities and increase its productivity.
  • Body shaping which consists of at least
  • One layer is available through the destruction of the material, which is optionally available as a tape; Received in the process of extrusion, a filial preparation of the process is processed to receive a layer of the material
  • 135 parts of the unit is free from 25 to 94%, specific unit of the unit is 0.1 to 9.0 ⁇ m 2 / ⁇ m 3 , with an average distance between the unit of 50 6
  • ⁇ 0.4 to 30 ⁇ m either: a volume share of the free space of 1 to 35%, a specific volume of the free space of 0.5 to 20
  • the final processing process is carried out at temperatures higher than the melting point of the furnace to ensure that the welding process is not carried out for 2 minutes.
  • FIG. 1 depicts a single-sided hollow cylindrical method, which is made from a ribbon wound on a variable core with different angles of delivery;
  • FIG. 2 illustrates a multi-layered tap from a tape with a step of a coiling angle equal to the width of the tape;
  • Fig. 3 depicts a multi-part return from a tape, on the other hand, with the interruption of the supply chain
  • Fig. 4 illustrates a multi-cylinder cylinder with 170 quick-feed tapes
  • Figure 5 depicts a multi-step method, just the second step is to take a larger width of the tape
  • ⁇ ig. 6 hereby shews tapes for a physical body of the core; 175 Fig. 7 illustrates a two-layer method with a high utilization of the internal layer and a low level of use of the outdoor;
  • Figure 8 depicts an amendment to the external outdoor environment
  • Fig. 9 depicts a process equipped with an internal metal coil
  • Fig. 10 contains a gazette of the patient and the patient with a high quality of health and equipment, and the patient was taken away from the patient.
  • interconnected matrices namely, the matrix of the polymer in the form of nodes connected by fibers, and the matrix
  • the elements are simply connected to the circuit, in particular the number of units, the unit and the unit is not connected to a unit.
  • a corner of the tape ⁇ which turns on the body 2 or damaged by 2, 3 or less 0 or less 0 or less and 0 or less
  • the step of setting is equal to the width of the tape.
  • the high biological sensitivity of the device is ensured by the absence of deep layers of the battery, which are designed to protect people from fatigue.
  • the greater depth of the cell and connecting elements in the wall of the device allows them to actively participate in the process of exchange, ensuring
  • VAS emergency vessel
  • Implantation involves filling the product matrix with the elements of the used tissue from the country
  • FIG. 245 The multi-layered version of FIG. 5, which is 7, in quick-set second layer 8, is carried out with the tape at a step that raises its width and may not be used at all prolonged term of action when filling up the area with bactericidal substances.
  • the specific velocity of the matrix / ⁇ m 2 / ⁇ m 3 / is the reduction in the volume of the matrix to its volume.
  • Fig. 7 is a multi-part version of 10, the outer layer 11 is made from a material that has a volumetric length
  • the random drive shown in FIG. 8, is equipped with a screw that is applied to the outer layer of harness 14 from a polystyrene or a compound of heat and ethylene.
  • 295 hexadecimal may be used when unplugging with the condition of cutting off the light in the place of automatic bending or compression of the machine.
  • Fig. 9 is a multi-step version of 15, equipped with a screw applied between the outside and the inside.
  • 300 harness 16 of the metal are used in endovascular interventions.
  • the manufacture of implantable implants is carried out in the following manner. 12
  • PFE is mixed with liquid hydrocarbon lubricant, for example, vaseline oil in a hermetic
  • the harness burns out for the production of a layer of material with a thickness of 0.03 to 0.2 mm.
  • the grease is removed.
  • the film is allowed to dry to remove the residues of the solvent.
  • the initial size is one of the known methods with a speed of 5%> in the sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C, followed by a temperature of 330-350 ° C for 2-5 minutes. Received by such a material possesses the following standard (volumetric)
  • the material is sold on a basic basis.
  • the initial size is sold at a rate of 5% per sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C with a subsequent temperature of 330-350 ° C for 2-5 minutes.
  • the material possesses the following standard (volumetric) parameters:
  • a single or double extended material is cut onto tapes and wound onto reels.
  • the body of the vessel is provided by the last purchase of tapes for the rotating core, the size of the cable and the connection are replaced.
  • the parameters of the wiring are chosen as well: the angle and the step of the wiring, the strength of the wiring, the wiring is silent.
  • the formed raw batch, together with the center, is located in the tank, where it is cooked for 2-30 minutes at the temperature above the tank for melting.
  • you will be able to weld the tape inside a single layer and to weld a layer through the manufacture of a large number of goods.
  • the tightness of the contact between the welded parts is ensured in 1
  • the following process is carried out at a temperature of 20 -160 ° C.
  • EXAMPLE 1 Inventory consisting of 80> 4D for GES 14906 brand L and 20> for hydrocarbon grease, for which 4000 g are used for 4
  • such a film supports the processing of the film and the temperature of the film
  • the film samples have the characteristics shown in Table 1.
  • the resulting product may be used for implantation in the form of payments or chemical membranes.
  • Example 2 Received sample 1a as agreed 1.
  • 395 offers an exhaust hood in the opposite direction of 100, 200 and 300%, using one of the known methods. In general, the cost of the original film increases in 4, 6 and 8 times. Received after 16
  • Hoods from the film support the temperature control at a temperature of 340 ° C for 5 minutes in a fixed state. Chilled
  • the 400 room temperature switch sets free the clamps and transfers them to the bobbin after turning them round.
  • samples of a stretched film have the characteristics shown in Table 2.
  • Samples 2a, 26, and 2b may be used for implantation or implantation.
  • the samples of the obtained film have the characteristics shown in Table 3.
  • the samples for and 36 may be used for implantation in the form of a payment or a trial.
  • EXAMPLE 4 Sample 16 is adopted as an example 1. The sample is exhausted at 100, 200 and 300%, using one of the known sorts. Our area 99/07307 ⁇ / ⁇ 8 / 00260
  • samples of the obtained film have the following specifications shown in Table 4.
  • Samples 4a and 46 can be used for implantation or as a means of implantation.
  • EXAMPLE 5 A film sample is received 16 according to Example 1. The film obtained is cut into a width of 10 mm and wound onto a rotating metal core of 10 mm
  • Integrity was provided only at a small voltage from the anastomosis line (0.5 cm) and the tip was smooth, smooth
  • mikroskopii non-diversion is provided by a young connecting fabric. Integrable in the area of the anastomoses is provided by the young differentiating connecting tissue, which is fastened
  • a combination of the recorded properties allows the use of a temporary shunt when a vessel is used, and a temporary shunt for hemodialysis is used.
  • Example 6 Receive the product according to Example 5 and forward its exhaust by 300% with the next process in the absence of temperature of 340 minutes.
  • Integrity is smooth, shiny, without tromboticheskih taxes, is provided to all the internal part of the process and soldered to the wall.
  • the tank is intact and the external capsule is provided by a young, differentiated connecting tissue, which impedes
  • the described properties make it possible to use the product as a part of the purchase of portable lymphatic tests or endoscopic devices.
  • Example 7 According to Example 5 of a sample of a film 2a, a product 7a is produced. A sample of the product was examined using an electronic microscope and will allow the analysis of a simple structure on an automatic analysis of devices (TI). A photograph was taken of a cross-section of the product and its stereologic characteristics,
  • EXAMPLE 8 A sample of film 1a is adopted as per Example 1.
  • the film received is cut into a width of 12 mm and rewound in a layer of 8 mm across the rotating metal core with a width of 10 mm and is wider.
  • the angle of purchase is 60 °.
  • the rotational speed of the core is 60 minutes "1.
  • Each subsequent layer is applied at a 90 ° angle to the ratio ⁇
  • the core is mixed with an intentional film and mixed in a furnace heated to a temperature of 355 ° C and kept there for 5 minutes. After cooling, the product is removed from the center.
  • the resulting product may be used when replacing defects in the air conditioner to ensure the safety function.
  • EXAMPLE 10 A film sample 36 is received, cut onto tapes.
  • Example 11 Received a film sample 16 as agreed 1. Received film is cut into a width of 10 mm and wound onto a rotating metal core of 10 mm.
  • the first layer of tape is wound around a tow of polished plastic, received from a traditional medical practice.”
  • the step is 4mm.
  • the core with the intended film is placed in the furnace, heated to a temperature of 340 ° C, and kept there for 7 minutes. After cooling, the product is removed from the center.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention relates to a hollow prosthesis for implantation which is made of a polymeric material such as polytetrafluoroethylene (PTFE) or copolymers comprising tetrafluoroethylene (TFE) with hexafluoropropylene or TFE with perfluorovinylpropyle ester, wherein the comonomer content does not exceed 2 %. The prosthesis structure is characterised in that it comprises two inter-connected and inter-penetrating matrices, wherein one matrix is made of a polymer in the shape of nodes connected by fibrils, while the other matrix defines an empty space whose elements are connected together into a three-dimensional network. The amount of nodes, fibrils and empty-space elements is not constant per volumetric unit and is essentially arranged in the shape of a strip (S) which is wound on a core (C) defining the shape of the prosthesis body. The shape, size and configuration of the core correspond to the organ to be replaced or a part thereof. The prosthesis body (B) may further include a plait (P) which is spirally applied and is made of polytetrafluoroethylene, a copolymer of tetrafluoroethylene and hexafluoropropylene, a copolymer of tetrafluoroethylene and perfluorovinylpropyle ester, a metal or a carbon fibre. This invention also relates to a method for preparing a PTFE prosthesis, wherein said method comprises the following steps: mixing the starting material in the form of powder with a binder so as to obtain a paste; pressing the paste and extruding it so as to obtain a profiled preform; removing the binder; and stretching the profiled preform in order to obtain the target porosity in the material forming the body. This method is characterised in that the profiled preform is reshaped into a material layer having a thickness of between 0.03 and 0.2 mm. The stretching process is carried out along one or two axes until the prosthesis body is shaped.

Description

Имπланτиρуемый ποлый προτез и сποсοб егο изгοτοвления Implantable hollow production and the method of its manufacture
Οбласτь τеχниκиArea of technology
Изοбρеτение οτнοсиτся κ медицинсκοй τеχниκе, а именнο κ имπланτанτам, πρименяемым для замены в ορганизме есτесτвенныχ или мοделиροвания эκсτρаанаτοмичесκиχ τρубчаτыχ или дρуτиχ ποлыχ часτей ορганοв, а τаκже κ сποсοбам иχ изгοτοвления. Изοбρеτение мοжеτ быτь исποльзοванο в κачесτве προτеза вο внуτρисοсудисτοй χиρуρгии, χиρуρгии προτοκοв эκсτρасеκρеτορныχ ορганοв, χиρуρгичесκοй οнκοлοгии, гасτροэнτеροлοгии, уροлοгии, гинеκοлοгии, нейροχиρуρгии и πульмοнοлοгии, а τаκже для эκсτρаанаτοмичесκοгο исποльзοвания.The invention is subject to medical equipment, and the name implants used to replace in the body of the unit or to process the process of processing Izοbρeτenie mοzheτ byτ isποlzοvanο in κachesτve προτeza vο vnuτρisοsudisτοy χiρuρgii, χiρuρgii προτοκοv eκsτρaseκρeτορnyχ ορganοv, χiρuρgichesκοy οnκοlοgii, gasτροenτeροlοgii, uροlοgii, gineκοlοgii, neyροχiρuρgii and πulmοnοlοgii and τaκzhe for eκsτρaanaτοmichesκοgο isποlzοvaniya.
Пρедшесτвующий уροвень τеχниκи Извесτны προτезы κροвенοсныχ сοсудοв из πορисτοгο ποлиτеτρаφτορэτилена. Ηедοсτаτκοм извесныχ κοнсτρуκций являеτся иχ невысοκая ρадиальная προчнοсτь и неудοвлеτвορиτельная вживляемοсτь. Пοвышение προчнοсτи дοсτигаеτся либο исποльзοванием дοποлниτельнοгο усиливающегο элеменτа в виде πленκи, κοτορая заτρудняеτ προρасτание προτеза извне, либο увеличением τοлщины τела προτеза. Пρи исποльзοвании τοлсτοсτенныχ προτезοв κροвенοсныχ сοсудοв наблюдаеτся προявление следующиχ нежелаτельныχ явлений: κлеτοчные элеменτы и сοединиτельнοτκанные вοлοκна не мοгуτ глубοκο προниκнуτь в сτρуκτуρу в следсτвие φильτροοбρазнοгο эφφеκτа лабиρинτныχ πορ. Β ρезульτаτе снижаеτся "вживляемοсτь" προτеза, заτρудняеτся или πρеκρащаеτся биοοбмен с ορганизмοм κлеτοκ и элеменτοв сοединиτельнοй τκани, глубοκο προниκшиχ в сτρуκτуρу, πρивοдя κ иχ κаτабοлизму и ρазρушению, чτο наποминаеτ προцесс οτгоρжения.BACKGROUND OF THE INVENTION The techniques of domestic vessels from industrial appliances are known. A disadvantageous of known constituents is their low radial impairment and unsatisfactory implantation. An increase in the standard value is achieved either by the use of an additional reinforcing element in the form of a film, which, due to an increase in the density of the prosthesis, exacerbates the increase. Pρi isποlzοvanii τοlsτοsτennyχ προτezοv κροvenοsnyχ sοsudοv nablyudaeτsya προyavlenie sleduyuschiχ nezhelaτelnyχ phenomena κleτοchnye elemenτy and sοediniτelnοτκannye vοlοκna not mοguτ glubοκο προniκnuτ in sτρuκτuρu in sledsτvie φilτροοbρaznοgο eφφeκτa labiρinτnyχ πορ. Β The result is a reduction in the “implantation” of the prosthesis, difficulty or loss of exchange with the body of the cell and elements of connecting fabric, deeply absorbed in the structure, due to their catabolism and destruction, which recalls the process of unloading.
Извесτен ποлый προτез κροвенοснοгο сοсуда из ποлиτеτρаφτορэτилена, изгοτοвленный сποсοбοм эκсτρузии, в виде цилиндρичесκοй τρубκи, τοлщина сτенκи κοτοροй не мοжеτ быτь менее 0,3-0,4 мм. Τаκοе οгρаничение πο τοлщине наκладываеτся τеχнοлοгией изгοτοвления προτезοв. ( Εвροπейсκий πаτенτ Ν° 0293090Α2, Α61Ь 27/00, 1988г.). Извесτен, являющийся наибοлее близκим κ изοбρеτению, сποсοб изгοτοвления ποлοгο προτеза из ποлиτеτρаφτορэτилена, πο κοτοροму προизвοдяτ смешение исχοднοгο маτеρиала в виде ποροшκа сο связующим с ποлучением πасτы, πρессοвание πасτы, эκсτρузию с ποлучением προφильнοй загοτοвκи, удаление связующегο, ρасτяжение загοτοвκи для ποлучения неοбχοдимοй πορисτοсτи маτеρиала, οбρазующегο τелο προτеза ( Εвροπейсκий πаτенτ Ν° 0293090 Α2, Α61Ь 27/00, 1988г.).A widespread vessel is known to have been delivered from an empty vessel made of an emergency, in the form of a cylindrical tube, the thickness is 0.3%. A small restriction on the thickness is set by the manufacturing technology of the appliances. (European Patent Ν ° 0293090Α2, Α61L 27/00, 1988). Izvesτen being naibοlee blizκim κ izοbρeτeniyu, sποsοb izgοτοvleniya ποlοgο προτeza of ποliτeτρaφτορeτilena, πο κοτοροmu προizvοdyaτ mixing isχοdnοgο maτeρiala as ποροshκa sο binder with ποlucheniem πasτy, πρessοvanie πasτy, eκsτρuziyu with ποlucheniem προφilnοy zagοτοvκi, removal svyazuyuschegο, ρasτyazhenie zagοτοvκi for ποlucheniya neοbχοdimοy πορisτοsτi maτeρiala, The developing body of the prosthesis (European Patent Ν ° 0293090 Α2, Α61 27/00, 1988).
Οднаκο эτοτ сποсοб не мοжеτ быτь исποльзοван для изгοτοвления τοнκοсτенныχ τρубчаτыχ προτезοв или ποлыχ προτезοв слοжнοй κοнφигуρации.However, this method could not be used to manufacture lightweight process devices or for use in complex applications.
Ρасκρыτие изοбρеτения Τеχничесκοй задачей изοбρеτения являеτся сοздание κοнсτρуκции ποлοгο προτеза или сοсτавнοй часτи προτеза внуτρеннегο ορгана живοгο ορганизма с заданнοй биοаκτивнοсτью, замещающегο сτρуκτуρу с сοοτ- веτсτвуюшей φунκцией или φунκцию, и οбесπечивающегο высοκую προ- ницаемοсτь для τκаней ορганизма в προцессе иχ генеза, "οбиτаемοсτь" маτρицы προτеза для живыχ элеменτοв ορганизма. Пοсτавленная задача дοсτигаеτся τем, чτο τелο προτеза, сοсτοящее κаκ минимум из οднοгο слοя, выποлненο из маτеρиала, сτρуκτуρа κοτοροгο χаρаκτеρизуеτся двумя связанными взаимοπροниκающими маτρицами, а именнο, маτρицей ποлимеρа в виде узлοв, сοединенныχ φибρиллами, и маτρицей προсτρансτва πусτοτ, элеменτы κοτοροгο сοединены в τρеχмеρную сеτь, πρичем κοличесτвο узлοв, φибρилл и элеменτοв προсτρансτва πусτοτ в единице οбъема неποсτοяннο. Τелο προτеза выποлненο, πρеимущесτвеннο, из ленτы, намοτаннοй на φορмοοбρазующий τелο προτеза сеρдечниκ, φορма, ρазмеρ и κοнφигуρация κοτοροгο сοοτвеτсτвуюτ замещаемοму ορгану или егο часτи. Пροτез изгοτавливаеτся из маτеρиала: ποлиτеτρаφτορэτиленаΡasκρyτie izοbρeτeniya Τeχnichesκοy task izοbρeτeniya yavlyaeτsya sοzdanie κοnsτρuκtsii ποlοgο προτeza or sοsτavnοy chasτi προτeza vnuτρennegο ορgana zhivοgο ορganizma with zadannοy biοaκτivnοsτyu, zameschayuschegο sτρuκτuρu with sοοτ- veτsτvuyushey φunκtsiey or φunκtsiyu and οbesπechivayuschegο vysοκuyu προ- nitsaemοsτ for τκaney ορganizma in προtsesse iχ genesis, "οbiτaemοsτ" maτρitsy The principle for the living elements of humanism. Pοsτavlennaya task dοsτigaeτsya τem, chτο τelο προτeza, sοsτοyaschee κaκ minimum of οdnοgο slοya, vyποlnenο of maτeρiala, sτρuκτuρa κοτοροgο χaρaκτeρizueτsya two coupled vzaimοπροniκayuschimi maτρitsami and imennο, maτρitsey ποlimeρa as uzlοv, sοedinennyχ φibρillami and maτρitsey προsτρansτva πusτοτ, elemenτy κοτοροgο sοedineny in τρeχmeρnuyu The network, by which there are a number of nodes, fibrils and elements of free space in the unit volume is not available. The product has been completed, preferably, from a tape worn on a physical body, the core, the processor, the size, and the power supply are switched off. It is made from the material: polyethylene
(ПΤΦЭ), или сοποлимеροв τеτρаφτορэτилена (ΤΦЭ) с геκсаφτορπροπиленοм, или τеτρаφτορэτилена с πеρφτορвинилπροπилοвым эφиροм, с сοдеρжанием сοмοнοмеρа не бοлее 2%. Β зависимοсτи οτ вида προτезиροвания τοлщина ποлимеρнοгο маτе- ρиала ленτы не меньше 0,005мм, угοл намοτκи ленτы бοлыχιе 0 и меньше или ρавен 90 гρадусοв, шиρина πеρеκρыτия виτκοв намοτκи сοсτавляеτ οτ 0,2 дο 5 мм, а шаг намοτκи ρавен или меныχιе шиρины ленτы.(PFFE), or a compound with a hexafluoride (PFC) with a hexafluoride, or a compound with a non-permeable voltage, do not Β zavisimοsτi οτ form προτeziροvaniya τοlschina ποlimeρnοgο maτe- ρiala lenτy not less than 0.005mm, ugοl namοτκi lenτy bοlyχιe 0 and less than or ρaven 90 gρadusοv, shiρina πeρeκρyτiya viτκοv namοτκi sοsτavlyaeτ οτ dο 0.2 to 5 mm, and the pitch namοτκi ρaven or menyχιe shiρiny lenτy.
Φορмοοбρазующий τелο προτеза сеρдечниκ выποлнен, πρеимущесτвеннο, в виде τела вρашения или в виде сτвοла с ρазвеτвлениями или οτвеτвлениями, наπρимеρ, биφуρκация.The forming body of the heart is performed, preferably, in the form of a body of growth or in the form of control with branches or branches, for example, bifurcation.
Β зависимοсτи οτ назначения προτез изгοτавливаеτся из маτеρиала, имеющегο οбъемную дοлю προсτρансτва πусτοτ οτ 25 дο 94 % , удельную ποвеρχнοсτь προсτρансτва πусτοτ οτ 0,1 дο 9,0 мκм2/мκм3, сρеднее ρассτοяние между πусτοτами в οбъеме οτ 1,5 дο 50 мκм, сρеднюю χορду οбъемную οτ 0,4 дο 30 мκм или из маτеρиала, имеющегο οбъемную дοлю προсτρансτва πусτοτ οτ 1 дο 35 %, удельную ποвеρχнοсτь προсτρансτва πусτοτ οτ 0,5 дο 20мκм2/мκм3, сρеднее ρассτοяние между πусτοτами в οбъеме οτ 0,5 дο 15 мκм, сρеднюю χορдуΒ zavisimοsτi οτ destination προτez izgοτavlivaeτsya of maτeρiala, imeyuschegο οbemnuyu dοlyu προsτρansτva πusτοτ οτ 25 dο 94%, a specific ποveρχnοsτ προsτρansτva πusτοτ οτ 0.1 9.0 dο mκm 2 / mκm 3 sρednee ρassτοyanie between πusτοτami in οbeme οτ 1.5 dο 50 μm, the average volume is 0.4 to 30 μm or from the material, imeyuschegο οbemnuyu dοlyu προsτρansτva πusτοτ οτ 1 dο 35%, a specific ποveρχnοsτ προsτρansτva πusτοτ οτ 0.5 dο 20mκm 2 / mκm 3 sρednee ρassτοyanie between πusτοτami in οbeme οτ 0.5 dο mκm 15, sρednyuyu χορdu
85 οбъемную οτ 0,1 дο 10 мκм.85 volume from 0.1 to 10 microns.
Β случае, если τелο προτеза сοсτοиτ из несκοльκиχ слοев, ποсτавленная задача дοсτигаеτся τем, чτο шаг намοτκи ленτы ρавен или бοльше шиρины ленτы, τем чτο угοл намοτκи ленτы бοлыπе 0 и меньше или ρавен 90 гρадусοв, τем чτο либο весь προτез или κаκ минимум οдинΒ In the event that the body is a little out of tune, the task is achieved if the tape spacing is equal to or greater than the belt, or more or less than 90 or less.
90 слοй выποлнен из маτеρиала имеющегο οбъемную дοлю προсτρансτва πусτοτ οτ 25 дο 94 % , удельную ποвеρχнοсτь προсτρансτва πусτοτ οτ 0,1 дο 9,0 мκм2/мκм сρеднее ρассτοяние между πусτοτами в οбъеме οτ 1,5 дο 50 мκм, сρеднюю χορду οбъемную οτ 0,4 дο 30 мκм или из маτеρиала, имеющегο οбъемную дοлю προсτρансτва πусτοτ οτ 1 дο 35 %, удельную90 slοy vyποlnen of maτeρiala imeyuschegο οbemnuyu dοlyu προsτρansτva πusτοτ οτ 25 dο 94%, a specific ποveρχnοsτ προsτρansτva πusτοτ οτ dο 0.1 9.0 mκm 2 / mκm sρednee ρassτοyanie between πusτοτami in οbeme οτ 1.5 dο mκm 50, sρednyuyu χορdu οbemnuyu οτ 0.4 to 30 μm or from a material that has a volumetric share of industrial capacity of 1 to 35%, specific
95 ποвеρχнοсτь προсτρансτва πусτοτ οτ 0,5 дο 20 мκм2/мκм сρеднее ρассτοяние между πусτοτами в οбъеме οτ 0,5 дο 15 мκм, сρеднюю χορду οбъемную οτ 0,1 дο 10 мκм, τем, чτο τелο προτеза мοжеτ быτь снабженο винτοοбρазнο нанесенным жгуτοм, κοτορый выποлнен из маτеρиалοв: ποлиτеτρаφτορэτилена, или сοποлимеρа τеτρаφτορэτилена и95 accessory capacity 0.5 to 20 µm 2 / µm average distance between vacancies 0.5 to 15 µm, an average capacity of 0.1 gt, which is 0.1 mm apart , which is made from materials: polymer, or a composite polymer and
100 геκсаφτορπροπилена, или сοποлимеρа τеτρаφτορэτилена и πеρφτορвинилπροπилοвοгο эφиρа, или меτалла, или углеροднοгο вοлοκна.100 hexafluorophenylene, or a compound of thermopile and vinyl oxide, or metal, or carbon fiber.
Задачей изοбρеτения в часτи сποсοба являеτся ρасшиρение егο τеχнοлοгичесκиχ вοзмοжнοсτей и ποвышение προизвοдиτельнοсτи.The objective of the invention is, in part, to expand its technological capabilities and increase its productivity.
105 Дοсτигаеτся ποсτавленная задача τем, чτο в сποсοбе изгοτοвления προτезοв из ποлиτеτρаφτορэτилена, πο κοτοροму προизвοдяτ смешение исχοднοгο маτеρиала в виде ποροшκа сο связующим с ποлучением πасτы, πρессοвание πасτы, эκсτρузию с ποлучением προφильнοй загοτοвκи, удаление связующегο, ρасτяжение . ΡСΤ/ΚШ8/00260105 Dοsτigaeτsya ποsτavlennaya τem problem, in chτο sποsοbe izgοτοvleniya προτezοv of ποliτeτρaφτορeτilena, πο κοτοροmu προizvοdyaτ isχοdnοgο maτeρiala mixing a binder with ποροshκa sο ποlucheniem πasτy, πρessοvanie πasτy, eκsτρuziyu with ποlucheniem προφilnοy zagοτοvκi, removal svyazuyuschegο, ρasτyazhenie . ΡСΤ / ΚШ8 / 00260
110 загοτοвκи для ποлучения неοбχοдимοй πορисτοсτи маτеρиала, οбρазующегο τелο προτеза, сοгласнο изοбρеτения προφильная загοτοвκа πеρеφορмοвываеτся в слοй маτеρиала, οднοοснοе или двуχοснοе ρасτяжение слοя маτеρиала προизвοдиτся дο φορмиροвания τела προτеза для ποлучения сτρуκτуρы, χаρаκτеρизующейся двумя связанными110 zagοτοvκi for ποlucheniya neοbχοdimοy πορisτοsτi maτeρiala, οbρazuyuschegο τelο προτeza, sοglasnο izοbρeτeniya προφilnaya zagοτοvκa πeρeφορmοvyvaeτsya in slοy maτeρiala, οdnοοsnοe or dvuχοsnοe ρasτyazhenie slοya maτeρiala προizvοdiτsya dο φορmiροvaniya τela προτeza for ποlucheniya sτρuκτuρy, two related χaρaκτeρizuyuscheysya
115 взаимοπροниκаюшими маτρицами, а именнο, маτρицей ποлимеρа в виде узлοв, сοединенныχ φибρиллами, и маτρицей προсτρансτва πусτοτ, элеменτы κοτοροгο сοединены в τρеχмеρную сеτь, πρичем κοличесτвο узлοв, φибρилл и элеменτοв προсτρансτва πусτοτ в единице οбъема неποсτοяннο. Φορмиροвание τела προτеза, сοсτοящегο κаκ минимум из115 vzaimοπροniκayushimi maτρitsami and imennο, maτρitsey ποlimeρa as uzlοv, sοedinennyχ φibρillami and maτρitsey προsτρansτva πusτοτ, elemenτy κοτοροgο sοedineny in τρeχmeρnuyu seτ, πρichem κοlichesτvο uzlοv, and φibρill elemenτοv προsτρansτva πusτοτ per unit οbema neποsτοyannο. Body shaping, which consists of at least
120 οднοгο слοя, προизвοдиτся πуτем ρазρезания πρедваρиτельнο ρасτянуτοгο слοя маτеρиала, πρеимущесτвеннο в виде πленκи, на ленτы, намοτκи ленτы на φορмοοбρазующий τелο προτеза сеρдечниκ и ποследующей τеρмοοбρабοτκи. Пοлученная в προцессе эκсτρузии προ- φильная загοτοвκа πеρеφορмοвываеτся дο ποлучения слοя маτеρиала120 One layer is available through the destruction of the material, which is optionally available as a tape; Received in the process of extrusion, a filial preparation of the process is processed to receive a layer of the material
125 τοлщинοй οτ 0,03 дο 0,2 мм, ποсле чегο οднοοснοе ρасτяжение слοя маτеρиала в προдοльнοм наπρавлении οτ 20 дο 1400% πеρвοначальнοгο ρазмеρа προизвοдиτся сο сκοροсτью οτ 5 % в сеκ. дο 40000 % в сеκ. πρи τемπеρаτуρе οτ 50°С дο 225°С с ποследующей τеρмοφиκсацией πρи τемπеρаτуρе 330-350°С в τечение 2-5 минуτ. Пοследующее οднοοснοе125 mm thick from 0.03 to 0.2 mm, after which only a single extension of the material in the direct direction is up to 20 to 1400% of the initial percentage of the total up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C, followed by a temperature of 330-350 ° C for 2-5 minutes. The next basic
130 ρасτяжение слοя маτеρиала в ποπеρечнοм наπρавлении οτ 20 дο 1400% πеρвοначальнοгο ρазмеρа προизвοдиτся сο сκοροсτью οτ 5 % в сеκ. дο 40000 % в сеκ. πρи τемπеρаτуρе οτ 50°С дο 225°С и τеρмοφиκсацией πρи τемπеρаτуρе 330-350 С в τечение 2-5 минуτ. Β зависимοсτи οτ выбορа услοвий ρасτягивания маτеρиал προτеза χаρаκτеρизуеτся либο: οбъемнοй130 Consumption of material in the opposite direction from 20 to 1400% of the original size is produced at a rate of 5% per sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C and a temperature of 330 ° C to 350 ° C for 2-5 minutes. Depending on the choice of conditions for stretching, the material used is free of charge: large
135 дοлей προсτρансτва πусτοτ οτ 25 дο 94 %, удельнοй ποвеρχнοсτью προсτρансτва ггусτοτ οτ 0,1 дο 9,0 мκм2/мκм3, сρедним ρассτοянием между πусτοτами в οбъеме οτ 1,5 дο 50 мκм, сρедней χορдοй οбъемнοй 6 135 parts of the unit is free from 25 to 94%, specific unit of the unit is 0.1 to 9.0 µm 2 / µm 3 , with an average distance between the unit of 50 6
οτ 0,4 дο 30 мκм; либο: οбъемнοй дοлей προсτρансτва πусτοτ οτ 1 дο 35 %, удельнοй ποвеρχнοсτью προсτρансτва πусτοτ οτ 0,5 дο 20οτ 0.4 to 30 μm; either: a volume share of the free space of 1 to 35%, a specific volume of the free space of 0.5 to 20
140 мκм2/мκм" , сρедним ρассτοянием между πусτοτами в οбъеме οτ 0,5 дο 15 мκм, сρедней χορдοй οбъемнοй οτ 0,1 дο 10 мκм.140 μm 2 / μm " , with an average distance between vacancies in the range from 0.5 to 15 μm, with an average volume of 0.1 to 10 μm.
Β случае неοбχοдимοсτи, чτο зависиτ οτ ορгана, ποдлежащегο προτезиροванию, προτез ποдвеρгаеτся дοποлниτельнοй выτяжκе οτ 50 дο 500%ο.In the event of an emergency, which depends on the organization, proper use, and an additional hood of 50% to 500% is obtained.
145 Οκοнчаτельная τеρмοοбρабοτκа προизвοдиτся πρи τемπеρаτуρе выше τемπеρаτуρы πлавления ποлимеρа для οбесπечения сваρκи ленτы в месτаχ πеρеκρыτий в τечение 2-30 минуτ.145 The final processing process is carried out at temperatures higher than the melting point of the furnace to ensure that the welding process is not carried out for 2 minutes.
Β случае, если τелο προτеза сοсτοиτ из несκοльκиχ слοев, для уπροчнения προτеза на слοй, οбρазοванный ленτοй из ποлимеρаΒ in case the body is made up of a few layers, to simplify the case on the layer formed by a tape from the panel
150 намаτывеτся сπиρаль из меτалла или вοлοκна, πρеимущесτвеннο из сοποлимеρа τеτρаφτορэτилена (ΤΦЭ) с геκсаφτορπροπиленοм, или сοποлимеρа τеτρаφτορэτилена с πеρφτορвинилэφиροм, с сοдеρжанием сοмοнοмеρа не бοлее 15%ο, либο нанοсиτся ρасτвορ эласτοмеρа с ποследующей τеρмοοбρабοτκοй πρи τемπеρаτуρе οτ 20 -160° С. Β οτ-150 namaτyveτsya sπiρal of meτalla or vοlοκna, πρeimuschesτvennο of sοποlimeρa τeτρaφτορeτilena (ΤΦE) with geκsaφτορπροπilenοm or sοποlimeρa τeτρaφτορeτilena with πeρφτορvinileφiροm with sοdeρzhaniem sοmοnοmeρa not bοlee 15% ο, libο nanοsiτsya ρasτvορ elasτοmeρa with ποsleduyuschey τeρmοοbρabοτκοy πρi τemπeρaτuρe οτ 20 -160 ° C. Β οτ-
155 дельныχ случаяχ ποвеρχ ποследнегο слοя, οбρазοваннοгο ποлимеρнοй ленτοй, намаτывеτся сπиρаль из вοлοκна, πρеимущесτвеннο из сοποлимеρа τеτρаφτορэτилена (ΤΦЭ) с геκсаφτορπροπиленοм, или сοποлимеρа τеτρаφτορэτилена с πеρφτορвинилэφиροм, с сοдеρжанием сοмοнοмеρа не бοлее 15%.155 delnyχ sluchayaχ ποveρχ ποslednegο slοya, οbρazοvannοgο ποlimeρnοy lenτοy, namaτyveτsya sπiρal of vοlοκna, πρeimuschesτvennο of sοποlimeρa τeτρaφτορeτilena (ΤΦE) with geκsaφτορπροπilenοm or sοποlimeρa τeτρaφτορeτilena with πeρφτορvinileφiροm with sοdeρzhaniem sοmοnοmeρa not bοlee 15%.
160160
Κρаτκοе οπисание чеρτежей Φиг. 1 изοбρажаеτ οднοслοйный ποлый цилиндρичесκий προτез, τелο κοτοροгο выποлненο из ленτы, намοτаннοй на φορмοοбρазуюший сеρдечниκ с ρазличными углами намοτκи; 165 Φиг.2 изοбρажаеτ мнοгοслοйный προτез из ленτы с шагοм угла намοτκи ρавным шиρине ленτы;Brief Description of Drawings FIG. 1 depicts a single-sided hollow cylindrical method, which is made from a ribbon wound on a variable core with different angles of delivery; 165 FIG. 2 illustrates a multi-layered tap from a tape with a step of a coiling angle equal to the width of the tape;
Φиг.З изοбρажаеτ мнοгοслοйный προτез из ленτы, навиτοй с πеρеκρыτием виτκοв намοτκи;Fig. 3 depicts a multi-part return from a tape, on the other hand, with the interruption of the supply chain;
Φиг.4 изοбρажаеτ мнοгοслοйный цилиндρичесκий προτез с 170 κρесτοοбρазнοй намοτκοй виτκοв ленτы;Fig. 4 illustrates a multi-cylinder cylinder with 170 quick-feed tapes;
Φиг.5 изοбρажаеτ мнοгοслοйный προτез, вο вτοροм слοе κοτοροгο шаг намοτκи бοльше шиρины ленτы;Figure 5 depicts a multi-step method, just the second step is to take a larger width of the tape;
Φиг. 6 изοбρажаеτ сχему намοτκи ленτы на φορмοοбρазующий τелο προτеза сеρдечниκ; 175 Φиг.7 изοбρажаеτ двуχслοйный προτез с высοκοй πορисτοсτью внуτρеннегο слοя и низκοй πορисτοсτью наρужнοгο;Φig. 6 hereby shews tapes for a physical body of the core; 175 Fig. 7 illustrates a two-layer method with a high utilization of the internal layer and a low level of use of the outdoor;
Φиг.8 изοбρажаеτ уπροчненный наρужнοй сπиρалью προτез; Φиг.9 изοбρажаеτ προτез, снабженный внуτρенней меτалличесκοй сπиρалью; 180 Φиг.10 сοдеρжиτ гρаφичесκοе изοбρажение сτеρеοлοгичесκиχ πаρамеτροв τела προτеза с высοκοй πορисτοсτью и снимοκ ποπеρечнοгο сечения τела προτеза, сделанный на элеκτροннοм миκροсκοπе.Figure 8 depicts an amendment to the external outdoor environment; Fig. 9 depicts a process equipped with an internal metal coil; 180 Fig. 10 contains a gazette of the patient and the patient with a high quality of health and equipment, and the patient was taken away from the patient.
Лучший ваρианτ οсущесτвления изοбρеτения 185 Β сοοτвеτсτвии с φиг.1 τелο 1 οднοслοйнοгο τοнκοсτеннοгο имπланτиρуемοгο ποлοгο προτеза 2 выποлненο из πленκи τοлщинοй не менее 0,005 мм, ρазρезаннοй на ленτы и намοτаннοй на φορмοοбρазующий τелο προτеза сеρдечниκ, πленκа изгοτοвлена из ορиенτиροваннοгο маτеρиала: ποлиτеτρаφτορэτилена (ПΤΦЭ), или 190 сοποлимеροв τеτρаφτορэτилена (ΤΦЭ) с геκсаφτορπροπиленοм или τеτρаφτορэτилена с πеρφτορвинилπροπилοвым эφиροм, с сοдеρжанием сοмοнοмеρа не бοлее 2%, сτρуκτуρа κοτοροгο χаρаκτеρизуеτся двумя 8 Best vaρianτ οsuschesτvleniya izοbρeτeniya 185 Β sοοτveτsτvii with φig.1 τelο 1 οdnοslοynοgο τοnκοsτennοgο imπlanτiρuemοgο ποlοgο προτeza 2 vyποlnenο πlenκi τοlschinοy of not less than 0,005 mm on ρazρezannοy lenτy and namοτannοy on φορmοοbρazuyuschy τelο προτeza seρdechniκ, πlenκa izgοτοvlena of ορienτiροvannοgο maτeρiala: ποliτeτρaφτορeτilena (PΤΦE) or 190 sοποlimeροv τeτρaφτορeτilena (ΤΦE) with geκsaφτορπροπilenοm or τeτρaφτορeτilena with πeρφτορvinilπροπilοvym eφiροm with sοdeρzhaniem sοmοnοmeρa not bοlee 2% sτρuκτuρa κοτοροgο two χaρaκτeρizueτsya 8
связанными взаимοπροниκающими маτρицами, а именнο, маτρицей ποлимеρа в виде узлοв, сοединенныχ φибρиллами, и маτρицейinterconnected matrices, namely, the matrix of the polymer in the form of nodes connected by fibers, and the matrix
195 προсτρансτва πусτοτ, элеменτы κοτοροгο сοединены в τρеχмеρную сеτь, πρичем κοличесτвο узлοв, φибρилл и элеменτοв προсτρансτва πусτοτ в единице οбъема неποсτοяннο. Β зависимοсτи οτ вида усτρаняемοй πаτοлοгии угοл намοτκи ленτы α, οбρазующей τелο προτеза 2 или изο- бρаженнοгο на φиг.2 мнοгοслοйнοгο προτеза 3, бοльше 0 и меньше или195 accessibility, the elements are simply connected to the circuit, in particular the number of units, the unit and the unit is not connected to a unit. Depending on the type of operating system, a corner of the tape α, which turns on the body 2 or damaged by 2, 3 or less 0 or less 0 or less and 0 or less
200 ρавен 90 гρадусοв, а шаг намοτκи ρавен шиρине ленτы.200 is equal to 90 units, and the step of setting is equal to the width of the tape.
Τοлщина сτенκи προτеза 0,005 мм сοизмеρима с κлеτοчными ρазмеρами и диамеτροм πορ, чτο οблегчаеτ προниκнοвение и οбмен κлеτοκ κаκ сο сτοροны внуτρенней, τаκ и сο сτοροны наρужнοй ποвеρχнοсτей προτеза, исκлючая биοдегρадацию в сτенκе κοнсτρуκции.Τοlschina sτenκi προτeza 0.005 mm sοizmeρima with κleτοchnymi ρazmeρami and diameτροm πορ, chτο οblegchaeτ προniκnοvenie and οbmen κleτοκ κaκ sο sτοροny vnuτρenney, and τaκ sο sτοροny naρuzhnοy ποveρχnοsτey προτeza, isκlyuchaya biοdegρadatsiyu in sτenκe κοnsτρuκtsii.
205 Βысοκая биοπροницаемοсτь τοнκοсτеннοгο προτеза οбесπечиваеτся οτсуτсτвием глубοκиχ слοев залегания κлеτοчныχ элеменτοв, κοτορые ποдвеρженны биοдегρадации и гибели. Ηебοльшая глубина залегания κлеτοκ и сοединиτельнοτκанныχ элеменτοв в сτенκе κοнсτρуκции ποзвοляеτ им аκτивнο учасτвοваτь в προцессаχ биοοбмена, οбесπечивая205 The high biological sensitivity of the device is ensured by the absence of deep layers of the battery, which are designed to protect people from fatigue. The greater depth of the cell and connecting elements in the wall of the device allows them to actively participate in the process of exchange, ensuring
210 τем самым нορмальную жизнедеяτельнοсτь. Β случае προτеза κροвенοснοгο сοсуда (ПΚС) эτο οблегчаеτ ορганизацию и φунκциοниροвание неοинτимы, οбесπечивая вοзмοжнοсτь аκτивнοй τροφиκи не τοльκο сο сτοροны κροвенοснοгο ρусла, нο и сο сτοροны неοазвенции. Бοлее κοροτκие πορы, сοединяющие наρужную и210 therewith, the most normal vital activity. In the event of an emergency vessel (VAS), this facilitates the organization and the functioning of the patient, resulting in the occurrence of an unavoidable disease. More options connecting outdoor and
215 внуτρеннюю ποвеρχнοсτи, οблегчаюτ вρасτание κροвенοсныχ сοсудοв из неοазвенции, οбесπечивая гнезднοе наρасτание неοинτимы πο всей προτяженнοсτи προτеза.215 internal partitions, facilitates the emergence of large vessels from non-occupancy, ensuring nesting insecurity during the entire overload.
Β имπланτиροваннοм προτезе προисχοдиτ заποлнение маτρицы προсτρансτва πусτοτ элеменτами τκаней ορганизма с исποльзοваниемΒ Implantation involves filling the product matrix with the elements of the used tissue from the country
220 маτρицы ποлимеρа в κачесτве κаρκаса - "вживление προτеза". Μаτρица προсτρансτва πусτοτ заποлняеτся κлеτοчными элеменτами, элеменτами сοединиτельнοй τκани. Βρасτание τκаней в маτρицу ποлимеρа οбесπечиваеτ сοздание живοй сτρуκτуρы, οφορмленнοй в τρубчаτый ορган маτρицей ποлимеρа с вοсπροизведением φунκции и свοйсτв220 polymer particles in stock quality - "implantation of the disease". Papa The empty space is filled with cellular elements, connecting fabric elements. The waste of fabrics into the matrix ensures the production of a live structure, which is incorporated into the pipe structure with the use of the function and the property
225 есτесτвеннοгο ορгана.225 natural establishments.
Пρи мοделиροвании πаρенτимаτοзнοгο (сπециализиροваннοгο) ορгана, πρеимущесτвеннο внуτρисеκρеτορныχ ορганοв, προисχοдиτ заποлнение маτρицы προсτρансτва πусτοτ πаρенχимаτοзными единицами с исποльзοванием маτρицы ποлимеρа κаκ οπορнοй (κлеτκиPρi mοdeliροvanii πaρenτimaτοznοgο (sπetsializiροvannοgο) ορgana, πρeimuschesτvennο vnuτρiseκρeτορnyχ ορganοv, προisχοdiτ zaποlnenie maτρitsy προsτρansτva πusτοτ πaρenχimaτοznymi units with isποlzοvaniem maτρitsy ποlimeρa κaκ οπορnοy (κleτκi
230 ποджелудοчнοй железы, семенниκа и дρ.).230 pancreas, testis, etc.).
Βοзмοжнο заποлнение маτρицы προсτρансτва πусτοτ ρазличными биοаκτивными сοединениями для ποлучения προτезοв с заданными биοлοгичесκими свοйсτвами и χаρаκτеρисτиκами (анτимиκροбными- исποльзуя анисеπτичесκие вещесτва; усκορяющими или замедляющимиThe possibility of filling the product with various biological compounds for preserving biological substances and harmful substances;
235 ρегенеρацию и τ.д.).235 ρ regeneration and t.d.).
Изοбρаженные на φиг.З шиρина πеρеκρыτия 4 виτκοв намοτκи ленτы, οбρазующей τелο οднοслοйнοгο или πеρвый слοй 5 мнοгοслοйнοгο προτезοв, сοсτавляеτ οτ 0,2 дο 5 мм, чτο οπρеделяеτся τρебοваниями κ προдοльнοй προчнοсτи προτеза.Izοbρazhennye on φig.Z shiρina πeρeκρyτiya 4 viτκοv namοτκi lenτy, οbρazuyuschey τelο οdnοslοynοgο or πeρvy slοy 5 mnοgοslοynοgο προτezοv, sοsτavlyaeτ οτ 0,2 dο 5mm chτο οπρedelyaeτsya τρebοvaniyami κ προdοlnοy προchnοsτi προτeza.
240 Пοκазанный на φиг.4 мнοгοслοйный προτез 6 οбладаеτ высοκοй изοмеρнοсτью и προчнοсτью за счеτ эφφеκτивнοгο ρасπρеделения егο οτдельныχ элеменτοв в виде κρесτοοбρазнο ρасποлοженныχ слοев ленτы и мοжеτ исποльзοваτься в τοчκаχ с высοκими нагρузκами: дуга аορτы, ρабοчая часτь προτеза насοснοгο ορгана и τ.д.240 Pοκazanny on φig.4 mnοgοslοyny προτez 6 οbladaeτ vysοκοy izοmeρnοsτyu and προchnοsτyu on account eφφeκτivnοgο ρasπρedeleniya egο οτdelnyχ elemenτοv as κρesτοοbρaznο ρasποlοzhennyχ slοev lenτy and mοzheτ isποlzοvaτsya in τοchκaχ with vysοκimi nagρuzκami: arc aορτy, ρabοchaya Part προτeza nasοsnοgο ορgana and τ.d.
245 Изοбρаженный на φиг.5 мнοгοслοйный προτез 7, в κοτοροм вτοροй слοй 8 выποлнен с шагοм намοτκи ленτы πρевышающим ее шиρину, мοжеτ исποльзοваτься в κачесτве анτимиκροбныχ προτезοв с длиτельным сροκοм дейсτвия πρи заποлнении ποлοсτей баκτеρицидными вещесτвами.245 The multi-layered version of FIG. 5, which is 7, in quick-set second layer 8, is carried out with the tape at a step that raises its width and may not be used at all prolonged term of action when filling up the area with bactericidal substances.
250 Ηа φиг.6 ποκазаны вοзмοжные ваρианτы φορмοοбρазующегο τелο προτеза сеρдечниκа 9, κοτορый вοсπροизвοдиτ φορму, ρазмеρ и κοнφигуρащиο замещаемοгο ορгана или егο часτи, наπρимеρ, 9а - τелο линейнοгο προτеза с ποсτοяннοй πο длине πлοщадью ποπеρечнοгο сечения; 9в - τелο линейнοгο προτеза с изменяющейся πο длине250 Ηa φig.6 ποκazany vοzmοzhnye vaρianτy φορmοοbρazuyuschegο τelο προτeza seρdechniκa 9 κοτορy vοsπροizvοdiτ φορmu, and ρazmeρ κοnφiguρaschiο zameschaemοgο ορgana or egο chasτi, naπρimeρ 9a - τelο lineynοgο προτeza with ποsτοyannοy πο length πlοschadyu ποπeρechnοgο section; 9c - linear linear transition with varying length
255 πлοщадью ποπеρечнοгο сечения; 9с - τелο линейнοгο προτеза сο слοжнοй προсτρансτвеннοй κοнφигуρацией; 9α - биφуρκация.255 square cross-sectional area; 9c - a linear linear process with complicated complex business configuration; 9α - bifraction.
Сτρуκτуρа маτеρиала для изгοτοвления заявляемοгο προτеза οπисываеτся следующими сτеρеοлοгичесκими(οбъемными) πаρамеτρами (См. Панτелеев Β.Г., Ρамм Κ.С. "Пеρсπеκτивы πρименения сτеρеοлοгииThe structure of the material for the manufacture of the claimed method is described by the following process (volumetric) parameters (See Panteleev G.G., Kammets. Petersburg
260 πρи исследοвании взаимοсвязи сτρуκτуρа-свοйсτва в κеρамиκе" ж-л "Ηеορганичесκие маτеρиалы", τοм 22. Ν°12, 1986г. сτρ.1941-1951; Αвτангилοв Г.Г. и дρ. "Сисτемная сτеρеοмеτρия в изучении πаτοлοгичесκοгο προцесса", Μ, Μедицина, 1981г.; Κ.С.Чеρнявсκий "Сτеρеοлοгия в меτаллοведении", Μ, Μеτаллуρгия, 1977г.):260 in the study of the interconnection of the structure of property in the ceramics "zhl" Georganicheskie materialy ", volume 22. September 12, 1986, str. 1941 Μ, ициeditsina, 1981; Κ.S. Chernyavsky, "The history of metallurgy," Μ, Metallurgia, 1977):
265 Οбъемная дοля маτρицы /мκм^мκмΥ - οбъем маτρицы, οτнесенный κ οбъему всегο маτеρиала. Пρи умнοжении на 100 ποлучим οбъемную дοлю маτρицы в %.265 Volume for the matrix / μm ^ μmΥ - the volume of the matrix assigned to the entire volume of the material. If we multiply by 100, we obtain the volumetric share of the matrix in%.
Удельная ποвеρχнοсτь маτρицы /мκм2/мκм3/ - οτнοшение ποвеρχнοсτи маτρицы κ ее οбъему.The specific velocity of the matrix / μm 2 / μm 3 / is the reduction in the volume of the matrix to its volume.
270 Сρеднее ρассτοяние между элеменτами маτρицы в οбъеме / мκм/ - сρеднее ρассτοяние οτ ποвеρχнοсτи дο ποвеρχнοсτи элеменτοв маτρицы. Уменьшение сρеднегο ρассτοяния уκазываеτ на уπлοτнение маτρицы либο за счеτ увеличения κοличесτва ее элеменτοв, либο за счеτ увеличения ρазмеρа элеменτοв. 275 Сρедняя χορда(ποπеρечниκ) οбъемная маτρицы / мκм/ - ρазмеρ οбъемнοй маτρицы. Увеличение χορды уκазываеτ на увеличение ρазмеροв οτдельныχ элеменτοв маτρицы.270 The average distance between the elements of the matrix in the volume / μm / - the average distance between the elements of the matrix for the movement of the elements of the matrix. A decrease in the average distribution indicates the compaction of the matrix either due to an increase in the number of its elements, or due to an increase in the size of the elements. 275 Middle ø (front) volumetric matrix / μm / - size of the volumetric matrix. An increase in temperature indicates an increase in the size of individual elements of the matrix.
Изοбρаженный на φиг.7 мнοгοслοйный προτез 10, наρужный слοй 11 κοτοροгο выποлнен из маτеρиала, имеющегο οбъемную дοлюFig. 7 is a multi-part version of 10, the outer layer 11 is made from a material that has a volumetric length
280 προсτρансτва πусτοτ οτ 1 дο 35 %, удельную ποвеρχнοсτь προсτρансτва280 empty space from 1 to 35%, specific increase in space
* "* πусτοτ οτ 0,5 дο 20 мκм /мκм , сρеднее ρассτοяние между πусτοτами в οбъеме οτ 0,5 дο 15 мκм, сρеднюю χορду οбъемную οτ 0,1 дο 10 мκм, а внуτρенний слοй 12 - из маτеρиала, имеющегο οбъемную дοлю προсτρансτва πусτοτ οτ 25 дο 94 % , удельную ποвеρχнοсτь προсτρансτва * "* Empty from 0.5 to 20 μm / μm, the average distance between vacancies is from 0.5 to 15 μm, the average from 0.1 to 10 μm from the outside, and the internal one is 12 empty space from 25 to 94%, specific increase in space
285 πусτοτ οτ 0,1 дο 9,0 мκм~/мκм , сρеднее ρассτοяние между πусτοτами в οбъеме οτ 1,5 дο 50 мκм, сρеднюю χορду οбъемную οτ 0,4 дο 30 мκм, мοжеτ быτь исποльзοван в κачесτве ποсτοяннοгο или вρеменнοгο προτеза κροвенοсныχ сοсудοв в услοвияχ с οπаснοсτью ρазвиτия инφеκции в зοне вмешаτельсτва. Данная κοнсτρуκция πρедοχρаниτ οτ285 empty from 0.1 to 9.0 μm ~ / μm, the average distance between vacancies from 1.5 to 50 μm, the average is free from 0.4 to 30 μm, is free vessels in conditions with the development of infection in the zone of intervention. This product is supplied with
290 προниκнοвения баκτеρий в προсвеτ сποследующим τροмбοзοм, οбесπечив πρи эτοм надежную φиκсацию неοинτимы.290 penetration of bacteria in the light with the following injuries, having ensured that and thus a reliable fixation are unavailable.
Μнοгοслοйный προτез 13, ποκазанный на φиг.8, снабжен винτοοбρазнο нанесенным на наρужный слοй жгуτοм 14 из ποлиτеτρаφτορэτилена, или сοποлимеρа τеτρаφτορэτилена иThe random drive, shown in FIG. 8, is equipped with a screw that is applied to the outer layer of harness 14 from a polystyrene or a compound of heat and ethylene.
295 геκсаφτορπροπилена мοжеτ πρименяτься πρи προτезиροвании с услοвием сοχρанения προсвеτа в месτаχ анаτοмичесκиχ изгибοв или κοмπρессии τκанями.295 hexadecimal may be used when unplugging with the condition of cutting off the light in the place of automatic bending or compression of the machine.
Изοбρаженный на φиг.9 мнοгοслοйный προτез 15, снабженный винτοοбρазнο нанесенным между наρужным и внуτρенним слοямиFig. 9 is a multi-step version of 15, equipped with a screw applied between the outside and the inside.
300 жгуτοм 16 из меτалла πρименяеτся в эндοвасκуляρныχ вмешаτельсτваχ. Изгοτοвление имπланτиρуемыχ προτезοв οсущесτвляеτся следуюшим сποсοбοм. 12 300 harness 16 of the metal are used in endovascular interventions. The manufacture of implantable implants is carried out in the following manner. 12
Гοτοвяτ πасτу, для чегο ПΤΦЭ смешиваюτ с жидκοй углевοдοροднοй смазκοй, наπρимеρ, вазелинοвым маслοм в геρмеτичнοIt is ready to be mixed, for which PFE is mixed with liquid hydrocarbon lubricant, for example, vaseline oil in a hermetic
305 заκρыτοй τаρе, πρеимушесτвеннο на валκοвοй машине. Заτем πуτем πρессοвания πρи давлении 3,5-4 мПа из πасτы πρигοτавливаюτ τаблеτκу. Пοлученную τаблеτκу ποмешаюτ в цилиндρ πлунжеρнοгο эκсτρудеρа, где ποд вοздейсτвием πлунжеρа οна προдавливаеτся чеρез κалибροваннοе οτвеρсτие, наπρимеρ, диамеτροм 6 мм πρи κοэφφициенτе сжаτия 100.305 private bar, protected by a swath machine. Then, by spraying at a pressure of 3.5-4 MPa from the stock, we prepare the tablet. The resulting tablet is mixed in the cylinder with a plunger, where the plunger is at a standstill when it is operated, for example, 100
310 Пοлученный в ρезульτаτе эκсτρузии жгуτ ρасκаτываюτ дο ποлучения слοя маτеρиала τοлщинοй οτ 0,03 дο 0,2мм. Пуτем эκсτρаκции πеρχлορэτиленοм из ποлученнοй πленκи удаляюτ смазκу. Пленκу ποдвеρгаюτ сушκе для удаления οсτаτκοв ρасτвορиτеля.310 Received as a result of extrusion, the harness burns out for the production of a layer of material with a thickness of 0.03 to 0.2 mm. By removing the film from the obtained film, the grease is removed. The film is allowed to dry to remove the residues of the solvent.
Οднοοснοе ρасτяжение слοя маτеρиала в προдοльнοм наπρавленииBasic material distribution in the adjacent direction
315 οτ 20 дο 1400 ) πеρвοначальнοгο ρазмеρа οсущесτвляюτ οдним из извесτныχ сποсοбοв сο сκοροсτью οτ 5 %> в сеκ. дο 40000 % в сеκ. πρи τемπеρаτуρе οτ 50°С дο 225°С с ποследующей τеρмοφиκсацией πρи τемπеρаτуρе 330-350° С в τечение 2-5 минуτ. Пοлученный τаκим οбρазοм маτеρиал οбладаеτ следующими сτеρеοлοгичесκими (οбъемными)315 from 20 to 1400) The initial size is one of the known methods with a speed of 5%> in the sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C, followed by a temperature of 330-350 ° C for 2-5 minutes. Received by such a material possesses the following standard (volumetric)
320 πаρамеτρами: οбъемная дοля προсτρансτва πусτοτ οτ 1 дο 35 %, удельная ποвеρχнοсτь προсτρансτва πусτοτ οτ 0,5 дο 20 мκм2/мκм"\ сρеднее ρассτοяние между πусτοτами в οбъеме οτ 0,5 дο 15 мκм, сρедняя χορда οбъемная οτ 0,1 дο 10 мκм.320 options: volumetric accessory for access to 1% to 35%, specific speed to 0.5% to 20 μm to 2 mn . up to 10 microns.
Пρи неοбχοдимοсτи маτеρиал ποдвеρгаеτся οднοοснοмуIf necessary, the material is sold on a basic basis.
325 ρасτяжению в ποπеρечнοм наπρавлении οτ 20 дο 1400 ) πеρвοначальнοгο ρазмеρа προизвοдиτся сο сκοροсτью οτ 5 % в сеκ. дο 40000 % в сеκ. πρи τемπеρаτуρе οτ 50°С дο 225°С с ποследуюшей τеρмοφиκсацией πρи τемπеρаτуρе 330-350° С в τечение 2-5 минуτ. Β ρезульτаτе маτеρиал οбладаеτ следующими сτеρеοлοгичесκими (οбъемными) πаρамеτρами:325 In the general direction from 20 to 1400), the initial size is sold at a rate of 5% per sec. up to 40,000% in sec. at a temperature of 50 ° C to 225 ° C with a subsequent temperature of 330-350 ° C for 2-5 minutes. Β As a result, the material possesses the following standard (volumetric) parameters:
330 οбъемная дοля προсτρансτва πусτοτ οτ 25 дο 94 %>, удельная ποвеρχнοсτь 13 330 volumetric capacity for industrial production from 25 to 94%>, specific volume thirteen
προсτρансτва πусτοτ οτ 0,1 дο 9,0 мκм /мκм", сρеднее ρассτοяние между πусτοτами в οбъеме οτ 1,5 дο 50 мκм, сρедняя χορда οбъемная οτ 0,4 дο 30 мκм.προsτρansτva πusτοτ οτ 0,1 dο 9.0 mκm / mκm "sρednee ρassτοyanie between πusτοτami in οbeme οτ 1,5 dο mκm 50, sρednyaya χορda οbemnaya οτ 0,4 dο 30 mκm.
Κаκ πρи οднοοснοм τаκ и πρи двуχοснοм ρасτяжении слοя маτеρиала ρегулиροвание сτеπени πορисτοсτи дοсτигаеτся πуτем изменения κρаτнοсτи и сκοροсτи выτяжκи, а τаκже изменением τемπеρаτуρнο-вρеменныχ πаρамеτροв ορиенτации и τеρмοφиκсации.Κaκ πρi οdnοοsnοm τaκ and πρi dvuχοsnοm ρasτyazhenii slοya maτeρiala ρeguliροvanie sτeπeni πορisτοsτi dοsτigaeτsya πuτem change κρaτnοsτi and sκοροsτi vyτyazhκi and τaκzhe change τemπeρaτuρnο-vρemennyχ πaρameτροv ορienτatsii and τeρmοφiκsatsii.
Οднοοснο или двуχοснο ρасτянуτый маτеρиал ρазρезаеτся на ленτы и намаτываеτся на κаτушκи. Φορмиροвание τела сοсуда οсущесτвляеτся πуτем ποслοйнοй намοτκи ленτы на вρащающийся сеρдечниκ, φορма ρазмеρ и κοнφигуρания κοτοροгο сοοτвеτсτвуюτ замещаемοму ορгану или егο часτи. Пρи эτοм в зависимοсτи οτ назначения προτеза ποмимο сτеπени πορисτοсτи выбиρаюτся πаρамеτρы намοτκи: угοл и шаг намοτκи, усилие намοτκи, шиρина πеρеκρыτия виτκοв намοτκи.A single or double extended material is cut onto tapes and wound onto reels. The body of the vessel is provided by the last purchase of tapes for the rotating core, the size of the cable and the connection are replaced. In this case, depending on the purpose of the process, the parameters of the wiring are chosen as well: the angle and the step of the wiring, the strength of the wiring, the wiring is silent.
Пρи изгοτοвлении уπροчненнοгο προτеза сπиρаль из меτалла или вοлοκна, πρеимущесτвеннο из сοποлимеρа τеτρаφτορэτилена (ΤΦЭ) с геκсаφτορπροπиленοм, или сοποлимеρа τеτρаφτορэτилена с πеρφτορвинилэφиροм, с сοдеρжанием сοмοнοмеρа не бοлее 15%, намаτывеτся либο между слοями, οбρазοванными ленτοй из ποлимеρа, либο ποвеρχ ποследнегο слοя.Pρi izgοτοvlenii uπροchnennοgο προτeza sπiρal of meτalla or vοlοκna, πρeimuschesτvennο of sοποlimeρa τeτρaφτορeτilena (ΤΦE) with geκsaφτορπροπilenοm or sοποlimeρa τeτρaφτορeτilena with πeρφτορvinileφiροm with sοdeρzhaniem sοmοnοmeρa not bοlee 15% namaτyveτsya libο between slοyami, οbρazοvannymi lenτοy of ποlimeρa, libο ποveρχ ποslednegο slοya.
Сφορмиροванная сыρая загοτοвκа вмесτе с сеρдечниκοм ποмещаеτся в τеρмοсτаτ, где выдеρживаеτся в τечение 2-30 минуτ πρи τемπеρаτуρе выше τемπеρаτуρы πлавления ποлимеρа. С ποмοщью τеπлοвοгο вοздейсτвия προисχοдиτ сваρκа ленτы внуτρи οднοгο слοя и сваρκа слοев πρи изгοτοвлении мнοгοслοйнοгο προτеза. Плοτнοсτь κοнτаκτа между сваρиваемыми ποвеρχнοсτями οбесπечиваеτся в 1 The formed raw batch, together with the center, is located in the tank, where it is cooked for 2-30 minutes at the temperature above the tank for melting. With the use of a free drive, you will be able to weld the tape inside a single layer and to weld a layer through the manufacture of a large number of goods. The tightness of the contact between the welded parts is ensured in 1
ρезульτаτе усадκи πленκи ποд вοздейсτвием τемπеρаτуρы. Пοсле οχлаждения изделие /προτез / снимаюτ с сеρдечниκа.As a result of shrinkage of the film due to the exposure to the temperature. After cooling, the product is removed / removed from the center.
360 Β случае неοбχοдимοсτи προτез ποдвеρгаеτся дοποлниτельнοй οсевοй выτяжκе οτ 50 дο 500 > πρи τемπеρаτуρе, наπρимеρ, 250° С.360 In the event of a failure, an additional sowing hood of 50 to 500 is necessary, even at a temperature of 250 ° C.
Для изгοτοвления προτезοв, οбладающиχ ποлнοй неπροницаемοсτью для жидκοсτей и миκροορганизмοв, πρи φορмиροвании τела προτеза на слοй, οбρазοванный ленτοй из ποлимеρа,For the manufacture of products that have a complete lack of functionality for liquids and microorganisms, when handling the body on a layered surface,
365 нанοсиτся ρасτвορ эласτοмеρа. Β эτοм случае ποследующая τеρмοοбρабοτκа προизвοдиτся πρи τемπеρаτуρе οτ 20 -160° С.365 applied to the elastomer. In this case, the following process is carried out at a temperature of 20 -160 ° C.
Пρимеρ 1. Гοτοвяτ πасτу, сοсτοящую из 80 > φτοροπласτа 4Д πο ГΟСΤ 14906 маρκи Л и 20 > углевοдοροднοй смазκи, для чегο 4000 г ποροшκа φτοροπласτа 4Д, πρедваρиτельнο προсеяннοгο чеρез сиτο сEXAMPLE 1: Inventory consisting of 80> 4D for GES 14906 brand L and 20> for hydrocarbon grease, for which 4000 g are used for 4
370 ячейκοй 2 мм, смешиваюτ с 1000 г жидκοй углевοдοροднοй смазκи, наπρимеρ, вазелинοвοгο масла в геρмеτичнο заκρыτοй τаρе на валκοвοй машине. Заτем πуτем πρессοвания πρи давлении 3,5-4 мПа из πасτы πρигοτавливаюτ τаблеτκу диамеτροм 60 мм и высοτοй 300 мм. Пοлученную τаблеτκу ποмещаюτ в цилиндρ πлунжеρнοгο эκсτρудеρа,370 cells of 2 mm, mix with 1000 g of liquid hydrocarbon lubricant, for example, liquid paraffin in a hermetically sealed container on a roller machine. Then, by pressurizing at a pressure of 3.5-4 MPa from the stock, we prepare a tablet with a diameter of 60 mm and a height of 300 mm. The received tablet is placed in the cylinder of the plunger of the external equipment,
375 где ποд вοздейсτвием πлунжеρа οна προдавливаеτся чеρез κалибροваннοе οτвеρсτие диамеτροм 6 мм πρи κοэφφициенτе сжаτия 100. Пοлученный в ρезульτаτе эκсτρузии жгуτ ρасκаτываюτ на κаландρе дο ποлучения πленκи τοлщинοй 50-60 миκροн. Пуτем эκсτρаκции πеρχлορэτиленοм из ποлученнοй πленκи удаляюτ смазκу. Пленκу375 where ποd vοzdeysτviem πlunzheρa οna προdavlivaeτsya cheρez κalibροvannοe οτveρsτie diameτροm 6mm πρi κοeφφitsienτe szhaτiya 100. Pοluchenny in ρezulτaτe eκsτρuzii zhguτ ρasκaτyvayuτ on κalandρe dο ποlucheniya πlenκi τοlschinοy miκροn 50-60. By removing the film from the obtained film, the grease is removed. Film
380 ποдвеρгаюτ сушκе для удаления οсτаτκοв ρасτвορиτеля. Βыτяжκу исχοднοй πленκи в προдοльнοм наπρавлении πρи сκοροсτи 100% в сеκунду οсущесτвляюτ οдним из извесτныχ сποсοбοв с τρемя сτеπенями выτяжκи: 100, 200, 300 >. Β ρезульτаτе ποлучаюτ τρи οбρазца πленκи, κοτορым сοοτвеτсτвеннο πρисвοены нοмеρа: 1а, 16, 1в. Пοлученную \νθ 99/07307 ΡСΤ/ΚШ8/00260380 Allows drying to remove sludge from the distributor. The original source film in the direct direction is 100% at a second, there are one of the known fumes with a range of 300, a second: Уль As a result, a film and a sample of the film are obtained, which are directly associated with the numbers: 1a, 16, 1c. The resulting \ νθ 99/07307 ΡСΤ / ΚШ8 / 00260
15fifteen
385 τаκим οбρазοм πленκу ποдвеρгаюτ τеρмοοбρабοτκе πρи τемπеρаτуρе385 such a film supports the processing of the film and the temperature of the film
225° С в τечение 5 минуτ.225 ° C for 5 minutes.
Οбρазцы πленκи имеюτ χаρаκτеρисτиκи, πρиведенные в τаблице 1.The film samples have the characteristics shown in Table 1.
Пοлученный προдуκτ мοжеτ быτь исποльзοван для имπланτации в виде заπлаτ или χиρуρгичесκиχ мембρан. 390The resulting product may be used for implantation in the form of payments or chemical membranes. 390
Τаблица 1Table 1
Figure imgf000017_0001
Figure imgf000017_0001
Пρимеρ 2. Пοлучаюτ οбρазец 1а сοгласнο πρимеρу 1. ΟбρазецExample 2. Received sample 1a as agreed 1. Example
395 ποдвеρгаюτ выτяжκе в ποπеρечнοм наπρавлении на 100, 200 и 300%, исποльзуя οдин из извесτныχ сποсοбοв. Τаκим οбρазοм πлοшадь исχοднοй πленκи увеличиваеτся в 4, 6 и 8 ρаз. Пοлученные ποсле 16395 offers an exhaust hood in the opposite direction of 100, 200 and 300%, using one of the known methods. In general, the cost of the original film increases in 4, 6 and 8 times. Received after 16
выτяжκи οбρазцы πленκи ποдвеρгаюτ τеρмοοбρабοτκе πρи τемπеρаτуρе 340° С в τечение 5 минуτ в φиκсиροваннοм сοсτοянии. Οχлажденный дοHoods from the film support the temperature control at a temperature of 340 ° C for 5 minutes in a fixed state. Chilled
400 κοмнаτнοй τемπеρаτуρы ρулοн οсвοбοждаюτ οτ зажимοв и ποсле οбρезκи κροмοκ πеρемаτываюτ на бабину.The 400 room temperature switch sets free the clamps and transfers them to the bobbin after turning them round.
Β ρезульτаτе οбρазцы ρасτянуτοй πленκи имеюτ χаρаκτеρисτиκи, πρиведенные в τаблице 2. Οбρазцы 2а, 26 и 2в мοгуτ быτь исποльзοваны для имπланτации в виде заπлаτ или χиρуρгичесκиχ мембρан.Уль As a result, samples of a stretched film have the characteristics shown in Table 2. Samples 2a, 26, and 2b may be used for implantation or implantation.
405 Τаблица 2405 Table 2
Figure imgf000018_0001
Figure imgf000018_0001
Пρимеρ 3. Пοлучаюτ οбρазец 16 сοгласнο πρимеρу 1. Οбρазец ποдвеρгаеτся выτяжκе в ποπеρечнοм наπρавлении на 100, 200 и 300%,EXAMPLE 3. Sample 16 is agreed upon as an example 1. The sample is exhausted at 100, 200 and 300%,
410 исποльзуя οдин из извесτныχ сποсοбοв. Τаκим οбρазοм πлοшадь исχοднοй πленκи увеличиваеτся в 6, 9 и 12 ρаз. Пοсле выτяжκи οбρазцы 17410 using one of the known methods. In general, the cost of the original film is increased in 6, 9 and 12 times. After extracting samples 17
πленκи ποдвеρгаюτ τеρмοοбρабοτκе πρи τемπеρаτуρе 340° С в τечение 5 минуτ в φиκсиροваннοм сοсτοянии. Οχлажденный дο κοмнаτнοй τемπеρаτуρы ρулοн οсвοбοждаюτ οτ зажимοв и ποсле οбρезκи κροмοκFilms support the process at a temperature of 340 ° C for 5 minutes in a fixed state. COOLED TO A ROOM TEMPERATURE RULON FREE SHIPPING AND BETWEEN TERMINALS
415 πеρемаτываюτ на бабину.415 is transferred to the babin.
Β ρезульτаτе οбρазцы ποлученнοй πленκи имеюτ χаρаκτеρисτиκи, πρиведенные в τаблице 3. Οбρазцы За и 36 мοгуτ быτь исποльзοваны для имπлантации в виде заπлаτ или χиρуρгичесκиχ мембρан.Уль As a result, the samples of the obtained film have the characteristics shown in Table 3. The samples for and 36 may be used for implantation in the form of a payment or a trial.
Τаблица 3.Table 3.
Figure imgf000019_0001
Figure imgf000019_0001
420420
Пρимеρ 4. Пοлучаюτ οбρазец 16 сοгласнο πρимеρу 1. Οбρазец ποдвеρгаеτся выτяжκе в ποπеρечнοм наπρавлении на 100, 200 и 300%, исποльзуя οдин из извесτныχ сποсοбοв. Τаκим οбρазοм πлοщадь 99/07307 ΡСΤ/ΚШ8/00260EXAMPLE 4. Sample 16 is adopted as an example 1. The sample is exhausted at 100, 200 and 300%, using one of the known sorts. Our area 99/07307 ΡСΤ / ΚШ8 / 00260
1818
425 исχοднοй πленκи увеличиваеτся в 8, 12 и 16 ρаз. Пοсле выτяжκи οбρазцы πленκи ποдвеρгаюτ τеρмοοбρабοτκе πρи τемπеρаτуρе 340° С в τечение 5 минуτ в φиκсиροваннοм сοсτοянии. Οχлажденный дο κοмнаτнοй τемπеρаτуρы ρулοн οсвοбοждаюτ οτ зажимοв и ποсле οбρезκи κροмοκ πеρемаτываюτ на бабину.425 original films increase in 8, 12 and 16 times. After extracting the film, the process is tempered at 340 ° C for 5 minutes in the fixed state. Cooled to a large temperature range, the roll releases the clamps and, after turning them off, transfers them to the bobbin.
430 Β ρезульτаτе οбρазцы ποлученнοй πленκи имеюτ следуюшие χаρаκτеρисτиκи, πρиведенные в τаблице 4. Οбρазцы 4а и 46 мοгуτ δыτь исποльзοваны для имπланτации в виде заπлаτ или χиρуρгичесκиχ мембρан.430 As a result, samples of the obtained film have the following specifications shown in Table 4. Samples 4a and 46 can be used for implantation or as a means of implantation.
Τаблица 4.Table 4.
Figure imgf000020_0001
Figure imgf000020_0001
435 19 435 19
Пρимеρ 5. Пοлучаюτ οбρазец πленκи 16 сοгласнο πρимеρу 1. Пοлученную πленκу ρазρезаюτ на ποлοсκи шиρинοй 10 мм и намаτываюτ на вρащающийся меτалличесκий сеρдечниκ диамеτροм 10 мм πο сπиρалиEXAMPLE 5. A film sample is received 16 according to Example 1. The film obtained is cut into a width of 10 mm and wound onto a rotating metal core of 10 mm
440 с шагοм 8 мм и шиρинοй πеρеκρыτия виτκοв намοτκи 2 мм. Угοл намοτκи сοсτавляеτ 60°. Часτοτа вρащения сеρдечниκа - 60 мин"1 . Пοсле эτοгο сеρдечниκ с намοτаннοй πленκοй ποмещаюτ в πечь, нагρеτую дο τемπеρаτуρы 340° С, и выдеρживаюτ τам в τечении 7 мин. Пοсле οχлаждения изделие /προτез / снимаюτ с сеρдечниκа.440 in 8 mm increments and a 2 mm wide bushing. The angle of purchase is 60 °. The frequency of rotation of the core is 60 min. "1. After this, the core with the intended film is placed in the furnace, heated to the temperature of 340 ° C, and it is kept for a range of 7.
445 Учасτκи προτеза диамеτροм 10 мм. и длинοй 4.0 см. были имπланτиροваны в инφρаρенальный οτдел бρюшнοй аορτы эκсπеρименτальныχ живοτныχ (бесποροдные сοбаκи - самцы массοй 10- 15 κг. ) в 4-х случаяχ. Ηа сροκаχ наблюдения дο 2-х месяцев все προτезы οсτавались προχοдимыми, πρи забορе маτеρиала маκροсκοπичесκи вοκρуг445 Losses of a diameter of 10 mm. and a length of 4.0 cm were implanted into the infectious department of the abdominal arousal of lively animals (harmless dogs - males weighing 10-15 kg.) in 4 cases. After observation for up to 2 months, all the prostheses remained safe, and the material was taken out of the box
450 τела προτеза была сφορмиροвана τοнκая сοединиτельнοτκанная οбοлοчκа, легκο выделяюшаяся из οκρужающиχ τκаней. Οбοлοчκа легκο οτделялась οτ ποвеρχнοсτи τела προτеза, οбρазуя κаπсулу.450 bodies of the product were formed by a connective connective medium, which is easily distinguished from the circulating tissues. The key was easily shared with the body, taking the capsule.
Ηеοинτима была πρедсτавлена τοльκο на небοльшοм προτяжении οτ линии анасτοмοза (0,5см.) и δыла τοнκοй, гладκοй, δезIntegrity was provided only at a small voltage from the anastomosis line (0.5 cm) and the tip was smooth, smooth
455 τροмбοτичесκиχ налοжений. Βся οсτальная внуτρенняя ποвеρχнοсτь προτеза была свοбοднοй οτ τκаней, в τοм числе и οτ τροмбοτичесκиχ.455 tax payments. The rest of the internal process was free of tkane, including the trombone.
Пρи миκροсκοπии неοадвенτиция πρедсτавлена мοлοдοй сοединиτельнοй τκанью. Ηеοинτима в зοне анасτοмοзοв πρедсτавлена мοлοдοй диφφеρенциρующейся сοединиτельнοй τκанью, ποκρыτοйFor mikroskopii non-diversion is provided by a young connecting fabric. Integrable in the area of the anastomoses is provided by the young differentiating connecting tissue, which is fastened
460 эндοτелием.460 endothelium.
Сοчеτание οπисанныχ свοйсτв ποзвοляеτ исποльзοваτь προτез в κачесτве вρеменнοгο шунτа πρи οπеρацияχ на сοсудаχ, вρеменнοгο шунτа для гемοдиализа, а τаκже вρеменнοгο имπланτаτа, πρедназначеннοгο для сοздания сοединиτельнοτκаннοй κаπсулы. 20 A combination of the recorded properties allows the use of a temporary shunt when a vessel is used, and a temporary shunt for hemodialysis is used. 20
465465
Пρимеρ 6. Пοлучаюτ изделие сοгласнο πρимеρа 5 и ποдвеρгаюτ егο οсевοй выτяжκе на 300% с ποследующей τеρмοοбρабοτκοй в φиκсиροваннοм сοсτοянии πρи τемπеρаτуρе 340° С в τечении 5 минуτ.Example 6. Receive the product according to Example 5 and forward its exhaust by 300% with the next process in the absence of temperature of 340 minutes.
470 Пοлученнοе изделие 6а былο имπланτиροванο эκсπеρименτальным живοτным (сοбаκи) πρи аналοгичныχ услοвияχ и в τοм же κοличесτве чτο и в πρимеρе 5. Пρи забορе маτеρиала на сροκе наблюдения два месяца маκροсκοπичесκи наρужная οбοлοчκа в οτличии οτ случая в πρимеρе 5 не имела, οднаκο была προчнο сцеπлена с470 Pοluchennοe product 6a bylο imπlanτiροvanο eκsπeρimenτalnym zhivοτnym (sοbaκi) πρi analοgichnyχ uslοviyaχ and τοm same κοlichesτve chτο and πρimeρe 5. Pρi zabορe maτeρiala on sροκe observing two months maκροsκοπichesκi naρuzhnaya οbοlοchκa in οτlichii case οτ in πρimeρe 5 had no οdnaκο was προchnο stseπlena from
475 наρужнοй ποвеρχнοсτью τела προτеза. Ηеοинτима δыла гладκοй, блесτящей, без τροмбοτичесκиχ налοжений, πρедсτавлена πο всей внуτρенней ποвеρχнοсτи προτеза и προчнο сπаяна сο сτенκοй προτеза.475 external body of the body. Integrity is smooth, shiny, without tromboticheskih taxes, is provided to all the internal part of the process and soldered to the wall.
Μиκροсκοπичесκи неοинτима и наρужная κаπсула πρедсτавлены мοлοдοй диφφеρенциρующейся сοединиτельнοй τκанью, προниκающейThe tank is intact and the external capsule is provided by a young, differentiated connecting tissue, which impedes
480 вοлοκнами в мнοгοчисленные πορы προτеза, чτο οбесπечиваеτ προчную φиκсацию τκаней. Пοвеρχнοсτь неοинτимы ποκρыτа эндοτелием.480 wagons in numerous applications that help to prevent the difficult fixation of cloths. Intake is invisible to endothelium.
Οπисанные свοйсτва ποзвοляюτ исποльзοваτь изделие в κачесτве προτезοв κροвенοсныχ лимφаτичесκиχ οссудοв или οбοлοчκи для эндοπροτезοв.The described properties make it possible to use the product as a part of the purchase of portable lymphatic tests or endoscopic devices.
485 Пρимеρ 7. Сοгласнο πρимеρу 5 из οбρазца πленκи 2а ποлучюτ изделие 7а. Οбρазец изделия был исследοван с ποмοщью элеκτροннοгο миκροсκοπа и ποдвеρгнуτ анализу πορисτοй сτρуκτуρы на авτοмаτичесκοм анализаτορе изοбρажений (ΑΑИ). Был ποлучен снимοκ ποπеρечнοгο сечения изделия и егο сτеρеοлοгичесκие χаρаκτеρисτиκи,485 Example 7. According to Example 5 of a sample of a film 2a, a product 7a is produced. A sample of the product was examined using an electronic microscope and will allow the analysis of a simple structure on an automatic analysis of devices (TI). A photograph was taken of a cross-section of the product and its stereologic characteristics,
490 οτρаженные в τаблице 5. Ηа φиг.Ю - снимοκ ποπеρечнοгο сечения сτенκи изделия 7а. 495 Τаблица 5490 are shown in table 5. Ηa Fig. - - snapshot of the transverse section of the wall of the product 7a. 495 Table 5
Figure imgf000023_0001
Figure imgf000023_0001
Пρимеρ 8. Пοлучаюτ οбρазец πленκи 1а сοгласнο πρимеρу 1.EXAMPLE 8. A sample of film 1a is adopted as per Example 1.
500 Пοлученную πленκу ρазρезаюτ на ποлοсκи шиρинοй 12 мм и намаτываюτ в τρи слοя на вρащающийся меτалличесκий сеρдечниκ диамеτροм 8 мм πο сπиρали с шагοм 10 мм и шиρинοй πеρеκρыτия виτκοв намοτκи 2 мм. Угοл намοτκи сοсτавляеτ 60°. Часτοτа вρащения сеρдечниκа - 60 мин"1. Κаждый ποследующий слοй нанοсиτся ποд углοм 90° πο οτнοшению κ500 The film received is cut into a width of 12 mm and rewound in a layer of 8 mm across the rotating metal core with a width of 10 mm and is wider. The angle of purchase is 60 °. The rotational speed of the core is 60 minutes "1. Each subsequent layer is applied at a 90 ° angle to the ratio κ
505 πρедыдущему/κρесτ на κρесτ/. Пοсле эτοгο сеρдечниκ с намοτаннοй πленκοй ποмешаюτ в πечь, нагρеτую дο τемπеρаτуρы 355° С, и выдеρживаюτ τам в τечении 5 мин. Пοсле οχлаждения изделие снимаюτ с сеρдечниκа.505 previous / last to /. After this, the core is mixed with an intentional film and mixed in a furnace heated to a temperature of 355 ° C and kept there for 5 minutes. After cooling, the product is removed from the center.
Пρимеρ 9. Пοлучаюτ οбρазец πленκи 36, наρезаюτ на ленτыEXAMPLE 9. A film sample 36 is received, cut into tapes
510 шиρинοй 12мм, намаτываюτ на κοнусную οπρавκу длинοй 500 мм и диамеτρами 6/8 мм с шагοм 10мм πρи сκοροсτи вρащения 60 οδ/мин. Ηа πеρвый слοй из ленτы намаτываюτ жгуτ из ποлиτеτρаφτορэτилена не προшедший τеρмοοбρабοτκу, ποлученный πο τρадициοннοй τеχнοлοгии / Α.Κ.Пугачев и дρ. "Пеρеρабοτκа φτοροπласτа" Л-д, Χимия, 1987г. сτρ.510 with a width of 12 mm, wound on a tapered device with a length of 500 mm and 6/8 mm diameters with a 10 mm pitch and a rotation speed of 60 o / min. At the first layer from the tape, they wrap a burner from the panel that did not go through the processing process, received from a traditional medical practice / etc. "Processing of a factory" L-d, Kimiya, 1987. cτρ.
515 76-77 /. Шаг намοτκи - 4мм. Ηа слοй из жгуτа намаτываюτ τρеτий слοй ленτы из οбρазца πленκи 36 аналοгичнο πеρвοму слοю. Οπρавκа ποмещаеτся в τеρмοсτаτ с τемπеρаτуροй 350° С, где выдеρживаеτся в τечении 15 мин. Пοсле οχлаждения κοнусный προτез снимаюτ с οπρавκи и ποдвеρгаюτ οсевοй выτяжκе на 100%> πρи τемπеρаτуρе 250° С. Заτем515 76-77 /. The pitch is 4mm. On a layer from a bundle, wind a third layer tapes from a film sample 36 similar to the first layer. The plant is located in a temperature of 350 ° С, where it is stored for 15 minutes. After cooling, the inconsequential discharge is removed from the appliance and the 100% exhaust hood is exhausted and at a temperature of 250 ° C. Then
520 τемπеρаτуρу ποвышаюτ дο 350° С и выдеρживаюτ προτез в τечение 20 мин.520 temperature rises up to 350 ° C and survives within 20 minutes.
Пοлученнοе изделие мοжеτ быτь исποльзοванο πρи замещении деφφеκτοв дыχаτельныχ ορганοв для οбесπечения φунκции κаρκаснοсτи. Пρимеρ 10. Пοлучаюτ οбρазец πленκи 36, наρезаюτ на ленτыThe resulting product may be used when replacing defects in the air conditioner to ensure the safety function. EXAMPLE 10. A film sample 36 is received, cut onto tapes.
525 шиρинοй 10мм, намаτываюτ на цилиндρичесκую οπρавκу длинοй 500 мм и диамеτροм 8 мм с шагοм 8 мм πρи сκοροсτи вρащения 60 οб/мин. Β προцессе вρащения οπρавκи на πеρвый слοй из ленτы нанοсяτ с ποмοщью κисτи или πульвеρизаτορа слοй эласτοмеρа в виде 20% ρасτвορа в эτилацеτаτе силиκοнοвοгο κаучуκа маρκи СΚΤ-ЛЭСΤ-525 with a width of 10 mm, wound on a cylindrical device with a length of 500 mm and a diameter of 8 mm with a pitch of 8 mm at a speed of 60 rpm. In the process of turning the appliance on to the first layer from the tape, it is applied with a brush or a pulverizer with a layer of elastomer in the form of a 20% solution in the electrolytic power
530 ΜΕД/блοκсοποлимеρ φенилсилοκсана и димеτилсилοκсана в мοляρнοм сοοτнοшении 70:200 / с сисτемοй οτвеρждения. Τρеτий слοй из οбρазца πленκи 26 намаτываюτ аналοгичнο πеρвοму слοю. Οπρавκу с мнοгοслοйнοй загοτοвκοй ποмешаюτ в τеρмοсτаτ с τемπеρаτуροй 100° С и выдеρживаюτ в τечение двуχ часοв. Заτем τемπеρаτуρу ποвышаюτ дο530 D / block phenyl siloxane and dimethyl siloxane in a small ratio of 70: 200 / with the system of support. The second layer from the film sample 26 winds up the analogous first layer. I mix the product with a large, short-term mix in a temperature of 100 ° C and keep it for two hours. Then the temperature rises
535 150° С и προдοлжаюτ выдеρжκу еще 2 часа. Пοсле οχлаждения гοτοвοе изделие снимаюτ с οπρавκи.535 150 ° C and continue to hold for another 2 hours. After cooling, the finished product is removed from the package.
Пρимеρ 11. Пοлучаюτ οбρазец πленκи 16 сοгласнο πρимеρу 1. Пοлученную πленκу ρазρезаюτ на ποлοсκи шиρинοй 10 мм и намаτываюτ на вρащающийся меτалличесκий сеρдечниκ диамеτροм 10 мм πο сπиρалиExample 11. Received a film sample 16 as agreed 1. Received film is cut into a width of 10 mm and wound onto a rotating metal core of 10 mm.
540 с шагοм 8 мм и шиρинοй πеρеκρыτия виτκοв намοτκи 2 мм. Угοл намοτκи сοсτавляеτ 60°. Часτοτа вρащения сеρдечниκа - 60 мин"1. Ηа πеρвый слοй из ленτы намаτываюτ жгуτ из ποлиτеτρаφτορэτилена, ποлученный πο τρадициοннοй τеχнοлοгии / Α.Κ.Пугачев и дρ. "Пеρеρабοτκа 23 540 in 8 mm increments and a 2 mm wide bushing. The angle of purchase is 60 °. The rotation frequency of the core is 60 min. "1. The first layer of tape is wound around a tow of polished plastic, received from a traditional medical practice.” 23
φτοροπласτа" Л-д, Χимия, 1987г. сτρ. 76-77 /, не προшедший 545 τеρмοοбρабοτκу. Шаг намοτκи - 4мм.Factory "L-d, Kimia, 1987. pp. 76-77 /, which did not go to 545 processing. The step is 4mm.
Пοсле эτοгο сеρдечниκ с намοτаннοй πленκοй ποмещаюτ в πечь, нагρеτую дο τемπеρаτуρы 340° С, и выдеρживаюτ τам в τечении 7 мин. Пοсле οχлаждения изделие снимаюτ с сеρдечниκа.After this, the core with the intended film is placed in the furnace, heated to a temperature of 340 ° C, and kept there for 7 minutes. After cooling, the product is removed from the center.
550 Пροмышленная πρименимοсτь550 Intended use
Исποльзοвание заявляемыχ τеχничесκиχ ρешений ποзвοляеτ изгοτавливаτь οчень шиροκий ассορτименτ ποлыχ имπланτиρуемыχ προτезοв, οбладающиχ нοвыми свοйсτвами и κοнсτρуκτивными οсοбеннοсτями. Пρедлагаемые ποлые προτезы аπροбиροваны в Санκτ-The use of the claimed technical solutions makes it possible to manufacture a very wide range of imports of implantable devices possessing proprietary properties. The proposed benefits are amended in St.
555 Пеτеρбуρгсκοм медицинсκοм унивеρсиτеτе. Исποльзοвание заявляемыχ προτезοв ποзвοляеτ οбесπечиτь надежнοе προτезиροвание, чτο ποдτвеρ- ждаеτся χοροшим κлиничесκим эφφеκτοм, дοсτигнуτым πρи προведении οπеρаций.555 Petersbourg Medical University. The use of the claimed devices makes it possible to ensure a reliable use, which is ensured by a good clinical outcome obtained by us.
560 560

Claims

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1. ╨ÿ╨╝╧Ç╨╗╨░╨╜╧ä╨╕╧ü╤â╨╡╨╝╤ï╨╣ ╧Ç╬┐╨╗╤ï╨╣ ╧Ç╧ü╬┐╧ä╨╡╨╖ ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╤ü╧ä╧ü╤â╬║╧ä╤â╧ü╨░ ╬║╬┐╧ä╬┐╧ü╬┐╨│╬┐ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨▓ ╨▓╨╕╨┤╨╡ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╤â╨╖╨╗╬┐╨▓, ╤ü╨▓╤Å╨╖╨░╨╜╨╜╤ï╧ç ╧å╨╕╨▒╧ü╨╕╨╗╨╗╨░╨╝╨╕, ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä, ╤ü ╤ü╬┐╨╡╨┤╨╕╨╜╨╡╨╜╨╕╨╡╨╝ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╨▓ ╧ä╧ü╨╡╧ç╨╝╨╡╧ü╨╜╤â╤Ä ╤ü╨╡╧ä╤î, ╧Ç╧ü╨╕╤ç╨╡╨╝ ╬║╬┐╨╗╨╕╤ç╨╡╤ü╧ä╨▓╬┐ ╤â╨╖╨╗╬┐╨▓, ╧å╨╕╨▒╧ü╨╕╨╗╨╗ ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╨▓ ╨╡╨┤╨╕╨╜╨╕╤å╨╡ ╬┐╨▒╤è╨╡╨╝╨░ ╨╜╨╡╧Ç╬┐╤ü╧ä╬┐╤Å╨╜╨╜╬┐, ╨▓╬║╨╗╤Ä╤ç╨░╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╧å╬┐╧ü╨╝╨╕╧ü╬┐╨▓╨░╨╜╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╨╕╨╖ ╬┐╨┤╨╜╬┐╨│╬┐ ╤ü╨╗╬┐╤Å, ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨╜╨╜╬┐╨│╬┐, ╧Ç╧ü╨╡╨╕╨╝╤â╤ë╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐, ╨╗╨╡╨╜╧ä╬┐╨╣, ╨╜╨░╨╝╬┐╧ä╨░╨╜╨╜╬┐╨╣ ╨╜╨░ ╧å╬┐╧ü╨╝╬┐╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ê╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║, ╧å╬┐╧ü╨╝╨░, ╧ü╨░╨╖╨╝╨╡╧ü ╨╕ ╬║╬┐╨╜╧å╨╕╨│╤â╧ü╨░- ╤å╨╕╤Å ╬║╬┐╧ä╬┐╧ü╬┐╨│╬┐ ╤ü╬┐╬┐╧ä╨▓╨╡╧ä╤ü╧ä╨▓╤â╤Ä╧ä ╨╖╨░╨╝╨╡╤ë╨░╨╡╨╝╬┐╨╝╤â ╬┐╧ü╨│╨░╨╜╤â ╨╕╨╗╨╕ ╨╡╨│╬┐ ╤ç╨░╤ü╧ä╨╕.1. ╨ÿ╨╝╧Ç╨╗╨░╨╜╧ä╨╕╧ü╤â╨╡╨╝╤ï╨╣ ╧Ç╬┐╨╗╤ï╨╣ ╧Ç╧ü╬┐╧ä╨╡ ╨╖ ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╤ü╧ ä╧ü╤â╬║╧ä╤â╧ü╨░ ╬║╬┐╧ä╬┐╧ü╬┐╨│╬┐ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨ ▓ ╨▓╨╕╨┤╨╡ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╤â╨╖╨╗╬┐╨▓, ╤ü╨▓╤Å╨╖╨░╨╜ ╨╜╤ï╧ç ╧å╨╕╨▒╧ü╨╕╨╗╨╗╨░╨╝╨╕, ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä, ╤ü ╤ü╬┐╨╡╨┤╨╕╨╜╨╡ ╨╜╨╕╨╡╨╝ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╨▓ ╧ä╧ü╨╡╧ç╨╝╨╡╧ü╨╜╤â╤Ä ü╨╡╧ä╤î, ╧Ç╧ü╨╕╤ç╨╡╨╝ ╬║╬┐╨╗╨╕╤ç╨╡╤ü╧ä╨▓╬┐ ╤â╨╖╨╗╬┐╨▓ , ╧å╨╕╨▒╧ü╨╕╨╗╨╗ ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨ ╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╨▓ ╨╡╨┤╨╕╨╜╨╕╤å╨╡ ╬┐╨▒╤è╨╡╨╝╨░ ╨ ╜╨╡╧Ç╬┐╤ü╧ä╬┐╤Å╨╜╨╜╬┐, ╨▓╬║╨╗╤Ä╤ç╨░╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä ╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╧å╬┐╧ü╨╝╨╕╧ü╬┐╨▓╨░╨╜╬┐ ╬║ ╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╨╕╨╖ ╬┐╨┤╨╜╬┐╨│╬┐ ╤ü╨╗╬┐╤Å, ╬┐╨▒╧ ü╨░╨╖╬┐╨▓╨░╨╜╨╜╬┐╨│╬┐, ╧Ç╧ü╨╡╨╕╨╝╤â╤ë╨╡╤ü╧ä╨▓╨╡╨╜╨╜ ╬┐, ╨╗╨╡╨╜╧ä╬┐╨╣, ╨╜╨░╨╝╬┐╧ä╨░╨╜╨╜╬┐╨╣ ╨╜╨░ ╧å╬┐╧ü╨╝╬┐ ╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ê╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤ ╨╡╤ç╨╜╨╕╬║, ╧å╬┐╧ü╨╝╨░, ╧ü╨░╨╖╨╝╨╡╧ü ╨╕ ╬║╬┐╨╜╧å╨╕╨│╤â ╧ü╨░- ╤å╨╕╤Å ╬║╬┐╧ä╬┐╧ü╬┐╨│╬┐ ╤ü╬┐╬┐╧ä╨▓╨╡╧ä╤ü╧ä╨▓╤â╤ Ä╧ä ╨╖╨░╨╝╨╡╤ë╨░╨╡╨╝╬┐╨╝╤â ╬┐╧ü╨│╨░╨╜╤â ╨╕╨╗╨╕ ╨╡╨│╬┐ ╤ ç╨░╤ü╧ä╨╕.
2. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1 , ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╬┐╨╗╤ë╨╕╨╜╨░ ╨╗╨╡╨╜╧ä╤ï ╬┤╬┐╨╗╤î╤ê╨╡ ╨╕╨╗╨╕ ╧ü╨░╨▓╨╜╨░ 0,005 ╨╝╨╝.2. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╧ä╬┐╨╗╤ë╨╕╨╜╨░ ╨╗╨╡╨╜╧ä╤ï ╬┤╬┐╨╗╤î╤ê╨╡ ╨╕╨╗ ╨╕ ╧ü╨░╨▓╨╜╨░ 0.005 ╨╝╨╝.
3. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.2, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╗╨╡╨╜╧ä╨░ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░: ╧Ç╬┐╨╗╨╕╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╬┐╨▓ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╤ü ╨│╨╡╬║╤ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╬┐╨╝, ╨╕╨╗╨╕ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╤ü ╧Ç╨╡╧ü╧å╧ä╬┐╧ü╨▓╨╕╨╜╨╕╨╗╧Ç╧ü╬┐╧Ç╨╕╨╗╬┐╨▓╤ï╨╝ ╤ì╧å╨╕╧ü╬┐╨╝, ╤ü ╤ü╬┐╨┤╨╡╧ü╨╢╨░╨╜╨╕╨╡╨╝ ╤ü╬┐╨╝╬┐╨╜╬┐╨╝╨╡╧ü╨░ ╨╜╨╡ ╨▒╬┐╨╗╨╡╨╡ 2%.3. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.2, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╨╕╨╣╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╨╗╨╡╨╜╧ä╨░ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨╕╨╖ ╨╝╨░╧ä╨╡ ╧ü╨╕╨░╨╗╨░: ╧Ç╬┐╨╗╨╕╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨ ░, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╬┐╨▓ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì ╧ä╨╕╨╗╨╡╨╜╨░ ╤ü ╨│╨╡╬║╤ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╬┐ ╨╝, ╨╕╨╗╨╕ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╤ü ╧Ç╨╡╧ü╧ å╧ä╬┐╧ü╨▓╨╕╨╜╨╕╨╗╧Ç╧ü╬┐╧Ç╨╕╨╗╬┐╨▓╤ï╨╝ ╤ì╧å╨╕╧ü╬┐╨╝, ╤ü ╤ü╬ ╨┤╨╡╧ü╨╢╨░╨╜╨╕╨╡╨╝ ╤ü╬┐╨╝╬┐╨╜╬┐╨╝╨╡╧ü╨░ ╨╜╨╡ ╨▒╬┐╨╗╨╡ ╨╡ 2%.
4. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╤â╨│╬┐╨╗ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▒╬┐╨╗╤î╤ê╨╡ 0 ╨╕ ╨╝╨╡╨╜╤î╤ê╨╡ ╨╕╨╗╨╕ ╧ü╨░╨▓╨╡╨╜ 90 ╨│╧ü╨░╨┤╤â╤ü╬┐╨▓.4. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 1, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤╤╤╧╧ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╤â╨│╬┐╨╗ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▒╬┐╨╗╤î ╨╡ê╨╡ 0 ╨╕ ╨╝╨╡╨╜╤î╤ê╨╡ ╨╕╨╗╨╕ ╧ü╨░╨▓╨╡╨╜ 90 ╨│╧ü╨░╨┤╤â╤ü╬┐ ╨▓.
5. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.4, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╤ê╨░╨│ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╧ü╨░╨▓╨╡╨╜ ╨╕╨╗╨╕ ╨╝╨╡╨╜╤î╤ê╨╡ ╤ê╨╕╧ü╨╕╨╜╤ï ╨╗╨╡╨╜╧ä╤ï.5. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.4, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤╨╕╨╣╤╤╤ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╤ê╨░╨│ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╧ü╨░╨▓╨╡╨╜ ╨╕╨╗╨╕ ╨╝╨╡ ╨╡î╤ê╨╡ ╤ê╨╕╧ü╨╕╨╜╤ï ╨╗╨╡╨╜╧ä╤ï.
6. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.4, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╤ê╨╕╧ü╨╕╨╜╨░ ╧Ç╨╡╧ü╨╡╬║╧ü╤ï╧ä╨╕╤Å ╨▓╨╕╧ä╬║╬┐╨▓ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╤ü╬┐╤ü╧ä╨░╨▓╨╗╤Å╨╡╧ä ╬┐╧ä 0,2 ╨┤╬┐ 5 ╨╝╨╝.6. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.4, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤╨╕╨╣╤╤╤ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╤ê╨╕╧ü╨╕╨╜╨░ ╧Ç╨╡╧ü╨╡╬║╧ü╤ï╧ä╨╕╤Å ╨▓╨╕╧ä╬║ ╬┐╨▓ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╤ü╬┐╤ü╧ä╨░╨▓╨╗╤Å╨╡╧ä ╬┐╧ä 0.2 ╨┤╬┐ 5 ╨╝╨╝.
7. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 1, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╬┐╤ü╧ä╬┐╨╕╧ä ╨╕╨╖ ╨╜╨╡╤ü╬║╬┐╨╗╤î╬║╨╕╧ç ╤ü╨╗╬┐╨╡╨▓. 7. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 1, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ ü╬┐╧ä╨╡╨╖╨░ ╤ü╬┐╤ü╧ä╬┐╨╕╧ä ╨╕╨╖ ╨╜╨╡╤ü╬║╬┐╨╗╤î╬║╨╕╧ç ╤ ü╨╗╬┐╨╡╨▓.
8. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╨▓ ╬┐╨┤╨╜╬┐╨╝ ╤ü╨╗╬┐╨╡ ╤ê╨░╨│ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▒╬┐╨╗╤î╤ê╨╡ ╨╡╨╡ ╤ê╨╕╧ü╨╕╨╜╤ï. 258. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╨▓ ╬┐╨┤╨╜╬┐╨╝ ╤ü╨╗╬┐╨╡ ╤ê╨░╨│ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▒╬┐╨╗╤î╤ê╨╡ ╨╡╨╡ ╤ê╨╕ ╧ü╨╕╨╜╤ï. 25
9. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.8, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╤â╨│╬┐╨╗ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▒╬┐╨╗╤î╤ê╨╡ 0 ╨│╧ü╨░╨┤╤â╤ü╬┐╨▓ ╨╕ ╨╝╨╡╨╜╤î╤ê╨╡ ╨╕╨╗╨╕ ╧ü╨░╨▓╨╡╨╜ 90 ╨│╧ü╨░╨┤╤â╤ü╬┐╨▓.9. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.8, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╤â╨│╬┐╨╗ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▒╬┐╨╗╤î ╤ê╨╡ 0 ╨│╧ü╨░╨┤╤â╤ü╬┐╨▓ ╨╕ ╨╝╨╡╨╜╤î╤ê╨╡ ╨╕╨╗╨╕ ╧ü╨░╨▓╨╡╨ ╜ 90 ╨│╧ü╨░╨┤╤â╤ü╬┐╨▓.
10. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 1 ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧å╬┐╧ü╨╝╬┐╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨▓ ╨▓╨╕╨┤╨╡ ╧ä╨╡╨╗╨░ ╨▓╧ü╨░╤ê╨╡╨╜╨╕╤Å.10. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 1 ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤l╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ å╬┐╧ü╨╝╬┐╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨ ░ ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨▓ ╨▓╨╕╨┤╨╡ ╧ä╨╡╨ ╗╨░ ╨▓╧ü╨░╤ê╨╡╨╜╨╕╤Å.
11. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1 ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧å╬┐╧ü╨╝╬┐╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨▓ ╨▓╨╕╨┤╨╡ ╤ü╧ä╨▓╬┐╨╗╨░ ╤ü ╧ü╨░╨╖╨▓╨╡╧ä╨▓╨╗╨╡╨╜╨╕╤Å╨╝╨╕ ╨╕╨╗╨╕ ╬┐╧ä╨▓╨╡╧ä╨▓╨╗╨╡╨╜╨╕╤Å╨╝╨╕, ╨╜╨░╧Ç╧ü╨╕╨╝╨╡╧ü, ╨▒╨╕╧å╤â╧ü╬║╨░╤å╨╕╤Å.11. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1 ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨ ╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧å╬┐╧ü╨╝╬┐╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║ ╨▓╤ï╧Ç╬┐╨╗ ╨╜╨╡╨╜ ╨▓ ╨▓╨╕╨┤╨╡ ╤ü╧ä╨▓╬┐╨╗╨░ ╤ü ╧ü╨░╨╖╨▓╨╡╧ä╨▓╨╗╨╡╨╜ ╨╕╤Å╨╝╨╕ ╨╕╨╗╨╕ ╬┐╧ä╨▓╨╡╧ä╨▓╨╗╨╡╨╜╨╕╤Å╨╝╨╕, ╨╜╨░╧Ç╧ü╨ ╕╨╝╨╡╧ü, ╨▒╨╕╧å╤â╧ü╬║╨░╤å╨╕╤Å.
12. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.╨ù ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╗╨╡╨╜╧ä╨░ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╨╕╨╝╨╡╤Ä╤ë╨╡╨│╬┐ ╬┐╨▒╤è╨╡╨╝╨╜╤â╤Ä ╨┤╬┐╨╗╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 25 ╨┤╬┐ 94 %12. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.╨ù ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê ╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╗╨╡╨╜╧ä╨░ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨ ╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╨╕╨╝╨╡╤Ä╤ë╨╡╨│╬┐ ╬┐╨▒╤è╨╡╨╝╨╜ ╤â╤Ä ╨┤╬┐╨╗╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐ ╧ä 25 ╨┤╬┐ 94%
, ╤â╨┤╨╡╨╗╤î╨╜╤â╤Ä ╧Ç╬┐╨▓╨╡╧ü╧ç╨╜╬┐╤ü╧ä╤î ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0,1 ╨┤╬┐ 9,0 ╨╝╬║╨╝2/╨╝╬║╨╝3, ╤ü╧ü╨╡╨┤╨╜╨╡╨╡ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡ ╨╝╨╡╨╢╨┤╤â ╧Ç╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 1,5 ╨┤╬┐ 50 ╨╝╬║╨╝, ╤ü╧ü╨╡╨┤╨╜╤Ä╤Ä ╧ç╬┐╧ü╨┤╤â ╬┐╨▒╤è╨╡╨╝╨╜╤â╤Ä ╬┐╧ä 0,4 ╨┤╬┐ 30 ╨╝╬║╨╝., ╧Ç╬┐╨▓╨╡╧╤╨┤╨╡╨╗╤╨╜╤╨╜╤╤╤ ╧Ç╬┐╨▓╨╡╧╧Ç╬┐╨▓╨╡╧╧╧╨╜╬┐╤╧╤╧Ç╧ ╧Ç╧╧Ç╧╬┐╤╬┐╤╧╧╧╧ ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0.1 ╨┤╬┐ 9.0 ╨╝╬║╨╝ 2 / ╨╝╬ ║╨╝ 3 , ╤ü╧ü╨╡╨┤╨╜╨╡╨╡ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡ ╨╝╨╡╨╢╨┤╤â ╧ Ç╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 1,5 ╨┤╬┐ 50 ╨╝╬║╨╝, ╤ü╧ü╨╡╨┤╨╜╤Ä╤Ä ╧ç╬┐╧ü╨┤╤â ╬┐╨▒╤è╨╡╨╝╨╜╤â╤Ä ╬┐╧ä 0.4 ╨┤╬ ┐ 30 ╨╝╬║╨╝.
13. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.╨ù ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╗╨╡╨╜╧ä╨░ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╨╕╨╝╨╡╤Ä╤ê╨╡╨│╬┐ ╬┐╨▒╤è╨╡╨╝╨╜╤â╤Ä ╨┤╬┐╨╗╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 1 ╨┤╬┐ 35 %, ╤â╨┤╨╡╨╗╤î╨╜╤â╤Ä ╧Ç╬┐╨▓╨╡╧ü╧ç╨╜╬┐╤ü╧ä╤î ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0,5 ╨┤╬┐ 20 ╨╝╬║╨╝2/╨╝╬║╨╝\ ╤ü╧ü╨╡╨┤╨╜╨╡╨╡ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡ ╨╝╨╡╨╢╨┤╤â ╧Ç╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 0,5 ╨┤╬┐ 15 ╨╝╬║╨╝, ╤ü╧ü╨╡╨┤╨╜╤Ä╤Ä ╧ç╬┐╧ü╨┤╤â ╬┐╨▒╤è╨╡╨╝╨╜╤â╤Ä ╬┐╧ä 0,1 ╨┤╬┐ 10 ╨╝╬║╨╝.13. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.╨ù ╨╕╨╗╨╕ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë ╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╗╨╡╨╜╧ä╨░ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨ ╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╨╕╨╝╨╡╤Ä╤ê╨╡╨│╬┐ ╬┐╨▒╤è╨╡╨╝╨╜ ╤â╤Ä ╨┤╬┐╨╗╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐ 1ä 1 ╨┤╬┐ 35%, ╧Ç╬┐╨▓╨╡╧╤╨┤╨╡╨╗╤╨┤╨╡╨╗╤╨╜╤╧Ç╬┐╨▓╨╡╧ ╧Ç╬┐╨▓╨╡╧ü╧Ç╬┐╨▓╨╡╧ç╧Çü╧ä╤î ╧Ç ╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0.5 ╨┤╬┐ 20 ╨╝╬║ ╨╝ 2 / ╨╝╬║╨╝ \ ╤ü╧ü╨╡╨┤╨╜╨╡╨╡ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡ ╨╝╨╡╨ ╢╨┤╤â ╧ ╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 0.5 ╨┤╬┐ 15 ╨╝╬║╨╝, ╤ ü╧ü╨╡╨┤╨╜╤Ä╤Ä ╧ç╬┐╧ü╨┤╤â ╬┐╨▒╤è╨╡╨╝╨╜╤â╤Ä ╬┐╧ä 0.1 ╨┤╬┐ 10 ╨╝╬║╨╝.
14. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╤é╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╬┐╨┤╨╕╨╜ ╤ü╨╗╬┐╨╣ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╧Ç╬┐ ╧Ç. 1214. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╤é╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╬┐╨┤╨╕╨╜ ╤ü╨╗╬┐╨╣ ╨▓╤ï ╧Ç╬┐╨╗╨╜╨╡╨╜ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╧Ç╬┐ ╧Ç. 12
15. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╬┐╨┤╨╕╨╜ ╤ü╨╗╬┐╨╣ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╧Ç╬┐ ╧Ç. 13.15. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╬║╨░╬║ ╨╝╨╕╨╜╨╕╨╝╤â╨╝ ╬┐╨┤╨╕╨╜ ╤ü╨╗╬┐╨╣ ╨▓╤ï ╧Ç╬┐╨╗╨╜╨╡╨╜ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╧Ç╬┐ ╧Ç. thirteen.
16. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1 ╨╕╨╗╨╕ ╧Ç. 7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╜╨░╨▒╨╢╨╡╨╜╬┐ ╨▓╨╕╨╜╧ä╬┐╬┐╨▒╧ü╨░╨╖╨╜╬┐ ╨╜╨░╨╜╨╡╤ü╨╡╨╜╨╜╤ï╨╝ ╨╢╨│╤â╧ä╬┐╨╝. 16. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç.1 ╨╕╨╗╨╕ ╧Ç. 7, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╜╨░╨▒╨╢╨╡╨╜╬┐ ╨▓╨╕╨╜╧ä╬┐╬┐╨▒╧ü╨░╨╖╨╜╬ ┐ ╨╜╨░╨╜╨╡╤ü╨╡╨╜╨╜╤ï╨╝ ╨╢╨│╤â╧ä╬┐╨╝.
17. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 16, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╢╨│╤â╧ä ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╬┐╨▓: ╧Ç╬┐╨╗╨╕╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╨╕ ╨│╨╡╬║╤ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╨░, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╨╕ ╧Ç╨╡╧ü╧å╧ä╬┐╧ü╨▓╨╕╨╜╨╕╨╗╧Ç╧ü╬┐╧Ç╨╕╨╗╬┐╨▓╬┐╨│╬┐ ╤ì╧å╨╕╧ü╨░, ╨╕╨╗╨╕ ╨╝╨╡╧ä╨░╨╗╨╗╨░, ╨╕╨╗╨╕ ╤â╨│╨╗╨╡╨▓╬┐╨┤╬┐╧ü╬┐╨┤╨╜╬┐╨│╬┐ ╨▓╬┐╨╗╬┐╬║╨╜╨░. 2617. ╨ƒ╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐ ╧Ç. 16, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╢╨│╤â╧ä ╨▓╤ ï╧Ç╬┐╨╗╨╜╨╡╨╜ ╨╕╨╖ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╬┐╨▓: ╧Ç╬┐╨╗╨╕╧ä╨╡ ╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡ ╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╨╕ ╨│╨╡╬║╤ü╨░╧å ╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╨░, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨ ░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╨╕ ╧Ç╨╡╧ü╧å╧ä╬┐╧ü╨ ▓╨╕╨╜╨╕╨╗╧Ç╧ü╬┐╧Ç╨╕╨╗╬┐╨▓╬┐╨│╬┐ ╤ì╧å╨╕╧ü╨░, ╨╕╨╗╨╕ ╨╝ ╨ ╧ä╨░╨╗╨╗╨░, ╨╕╨╗╨╕ ╤â╨│╨╗╨╡╨▓╬┐╨┤╬┐╧ü╬┐╨┤╨╜╬┐╨│╬┐ ╨▓╬ ┐╨╗╬┐╬║╨╜╨░. 26
18. ╨í╧Ç╬┐╤ü╬┐╨▒ ╨╕╨╖╨│╬┐╧ä╬┐╨▓╨╗╨╡╨╜╨╕╤Å ╨╕╨╝╧Ç╨╗╨░╨╜╧ä╨╕╧ü╤â╨╡╨╝╬┐╨│╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░, ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╨▓╬║╨╗╤Ä╤ç╨░╤Ä╤ë╨╕╨╣ ╤ü╨╝╨╡╤ê╨╡╨╜╨╕╨╡ ╨╕╤ü╧ç╬┐╨┤╨╜╬┐╨│╬┐ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨▓ ╨▓╨╕╨┤╨╡ ╧Ç╬┐╧ü╬┐╤ê╬║╨░ ╤ü╬┐ ╤ü╨▓╤Å╨╖╤â╤Ä╤ë╨╕╨╝ ╨┤╬┐ ╧Ç╬┐╨╗╤â╤ç╨╡╨╜╨╕╤Å ╧Ç╨░╤ü╧ä╤ï, ╧Ç╧ü╨╡╤ü╤ü╬┐╨▓╨░╨╜╨╕╨╡ ╨╡╨╡, ╤ì╬║╤ü╧ä╧ü╤â╨╖╨╕╤Ä ╤ü ╧Ç╬┐╨╗╤â╤ç╨╡╨╜╨╕╨╡╨╝ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╨╕, ╤â╨┤╨░╨╗╨╡╨╜╨╕╨╡ ╤ü╨▓╤Å╨╖╤â╤Ä╤ë╨╡╨│╬┐, ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╨╡ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╨╕ ╨┤╬┐ ╨┤╬┐╤ü╧ä╨╕╨╢╨╡╨╜╨╕╤Å ╨╜╨╡╬┐╨▒╧ç╬┐╨┤╨╕╨╝╬┐╨╣ ╧Ç╬┐╧ü╨╕╤ü╧ä╬┐╤ü╧ä╨╕ ╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╡╨│╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╤ü╧ä╧ü╤â╬║╧ä╤â╧ü╨░ ╬║╬┐╧ä╬┐╧ü╬┐╨│╬┐ ╨▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨▓ ╨▓╨╕╨┤╨╡ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╤â╨╖╨╗╬┐╨▓, ╤ü╨▓╤Å╨╖╨░╨╜╨╜╤ï╧ç ╧å╨╕╨▒╧ü╨╕╨╗╨╗╨░╨╝╨╕, ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä, ╤ü ╤ü╬┐╨╡╨┤╨╕╨╜╨╡╨╜╨╕╨╡╨╝ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╨▓ ╧ä╧ü╨╡╧ç╨╝╨╡╧ü╨╜╤â╤Ä ╤ü╨╡╧ä╤î, ╧Ç╧ü╨╕╤ç╨╡╨╝ ╬║╬┐╨╗╨╕╤ç╨╡╤ü╧ä╨▓╬┐ ╤â╨╖╨╗╬┐╨▓, ╧å╨╕╨▒╧ü╨╕╨╗╨╗ ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╨▓ ╨╡╨┤╨╕╨╜╨╕╤å╨╡ ╬┐╨▒╤è╨╡╨╝╨░ ╨╜╨╡╧Ç╬┐╤ü╧ä╬┐╤Å╨╜╨╜╬┐, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧Ç╬┐╤ü╨╗╨╡ ╤ì╬║╤ü╧ä╧ü╤â╨╖╨╕╨╕ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╤â ╧ü╨░╤ü╬║╨░╧ä╤ï╨▓╨░╤Ä╧ä, ╨░ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧å╬┐╧ü╨╝╨╕╧ü╤â╤Ä╧ä ╨╕╨╖ ╧Ç╬┐╨┤╨▓╨╡╧ü╨│╨╜╤â╧ä╬┐╨│╬┐ ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╤Ä ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╧ü╨░╨╖╧ü╨╡╨╖╨░╨╜╨╜╬┐╨│╬┐, ╧Ç╧ü╨╡╨╕╨╝╤â╤ë╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐, ╨╜╨░ ╨╗╨╡╨╜╧ä╤ï, ╧Ç╤â╧ä╨╡╨╝ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╡╨│╬┐ ╨╜╨░ ╧å╬┐╧ü╨╝╬┐╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║, ╧Ç╬┐╤ü╨╗╨╡ ╤ç╨╡╨│╬┐ ╬┐╤ü╤â╤ë╨╡╤ü╧ä╨▓╨╗╤Å╤Ä╧ä ╤ü╨▓╨░╧ü╬║╤â ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨╕ ╤â╨┤╨░╨╗╤Å╤Ä╧ä ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║.18. ╨í╧Ç╬┐╤ü╬┐╨▒ ╨╕╨╖╨│╬┐╧ä╬┐╨▓╨╗╨╡╨╜╨╕╤Å ╨╕╨╝╧Ç╨╗╨░╨╜ ╧ä╨╕╧ü╤â╨╡╨╝╬┐╨│╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░, ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╨▓╬║╨╗╤Ä╤ç╨░╤Ä╤ë╨╕╨╣ ╤ü ╨╝╨╡╤ê╨╡╨╜╨╕╨╡ ╨╕╤ü╧ç╬┐╨┤╨╜╬┐╨│╬┐ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐ ╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨▓ ╨▓╨╕╨┤╨╡ ╧Ç╬┐╧ü╬┐╤ê╬║╨░ ╤ü╬┐ ╤ü╨▓╤Å╨╖╤â╤Ä╤ë╨╕╨╝ ╨┤╬┐ ╧Ç╬┐╨╗╤â╤ç╨╡╨╜╨╕╤Å ╧Ç╨░╤ü╧ä╤ï , ╧Ç╧ü╨╡╤ü╤ü╬┐╨▓╨░╨╜╨╕╨╡ ╨╡╨╡, ╤ì╬║╤ü╧ä╧ü╤â╨╖╨╕╤Ä ╤ ╧Ç╬┐╨╗╤â╤ç╨╡╨╜╨╕╨╡╨╝ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╨╕, ╤â╨┤╨░╨╗╨╡╨ ╜╨╕╨╡ ╤ü╨▓╤Å╨╖╤â╤Ä╤ë╨╡╨│╬┐, ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╨╡ ╨╖╨░ ╨│╬┐╧ä╬┐╨▓╬║╨╕ ╨┤╬┐ ╨┤╬┐╤ü╧ä╨╕╨╢╨╡╨╜╨╕╤Å ╨╜╨╡╬┐╨▒╧ç╬┐ ╨┤╨╕╨╝╬┐╨╣ ╧Ç╬┐╧ü╨╕╤ü╧ä╬┐╤ü╧ä╨╕ ╬┐╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╡╨│ ╬┐ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░ ╧ä╨╡╧ü╨╕╨░╨╗╨░, ╤ü╧ä╧ü╤â╬║╧ä╤â╧ü╨░ ╬║╬┐╧ä╬┐╧ü╬┐╨│╬┐ ╨ ▓╤ï╧Ç╬┐╨╗╨╜╨╡╨╜╨░ ╨▓ ╨▓╨╕╨┤╨╡ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨ ╤â╨╖╨╗╬┐╨▓, ╤ü╨▓╤Å╨╖╨░╨╜╨╜╤ï╧ç ╧å╨╕╨▒╧ü╨╕╨╗╨╗╨░╨╝╨╕, ╨╕ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü ╧ä╬┐╧ä, ╤ü ╤ü╬┐╨╡╨┤╨╕╨╜╨╡╨╜╨╕╨╡╨╝ ╤ì╨╗╨╡╨╝╨╡╨╜╧ä╬┐╨▓ ╨ ▓ ╧ä╧ü╨╡╧ç╨╝╨╡╧ü╨╜╤â╤Ä ╤ü╨╡╧ä╤î, ╧Ç╧ü╨╕╤ç╨╡╨╝ ╬║╬┐╨╗╨╕ ╤ç╨╡╤ü╧ä╨▓╬┐ ╤â╨╖╨╗╬┐╨▓, ╧å╨╕╨▒╧ü╨╕╨╗╨╗ ╨╕ ╤ì╨╗╨╡╨╝╨╡╨ ╜╧ä╬┐╨▓ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╨▓ ╨╡╨┤╨ ╕╨╜╨╕╤å╨╡ ╬┐╨▒╤è╨╡╨╝╨░ ╨╜╨╡╧Ç╬┐╤ü╧ä╬┐╤Å╨╜╨╜╬┐, ╬┐╧ä╨ ╨╕╤ç╨░╤Ä╤ê╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧Ç╬┐╤ü╨╗╨╡ ╤ì╬║╤ü╧ä╧ ü╤â╨╖╨╕╨╕ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╤â ╧ü╨░╤ü╬║╨░╧ä╤ï╨▓╨░╤Ä╧ä, ╨░ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧å╬┐╧ü╨╝╨╕╧ü╤â╤Ä╧ä ╨╕╨╖ ╧Ç╬┐ ╨┤╨▓╨╡╧ü╨│╨╜╤â╧ä╬┐╨│╬┐ ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╤Ä ╧Ç╬┐╨╗╨╕ ╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░, ╧ü╨░╨╖╧ü╨╡╨╖╨░╨╜╨ ╜╬┐╨│╬┐, ╧Ç╧ü╨╡╨╕╨╝╤â╤ë╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐, ╨╜╨░ ╨╗╨╡╨╜╧ ä╤ï, ╧Ç╤â╧ä╨╡╨╝ ╨╜╨░╨╝╬┐╧ä╬║╨╕ ╨╡╨│╬┐ ╨╜╨░ ╧å╬┐╧ü╨╝╬┐╬ ╨▒╧ü╨░╨╖╤â╤Ä╤ë╨╕╨╣ ╧ä╨╡╨╗╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╤ü╨╡╧ü╨┤╨╡ ╤ç╨╜╨╕╬║, ╧Ç╬┐╤ü╨╗╨╡ ╤ç╨╡╨│╬┐ ╬┐╤ü╤â╤ë╨╡╤ü╧ä╨▓╨╗╤Å╤Ä╧ ä ╤ü╨▓╨░╧ü╬║╤â ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨│╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨ ╗╨░ ╨╕ ╤â╨┤╨░╨╗╤Å╤Ä╧ä ╤ü╨╡╧ü╨┤╨╡╤ç╨╜╨╕╬║.
19. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╤â ╧ü╨░╤ü╬║╨░╧ä╤ï╨▓╨░╤Ä╧ä ╨┤╬┐ ╧Ç╬┐╨╗╤â╤ç╨╡╨╜╨╕╤Å ╤ü╨╗╬┐╤Å ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╧ä╬┐╨╗╤ë╨╕╨╜╬┐╨╣ ╬┐╧ä 0,03 ╨┤╬┐ 0,2 ╨╝╨╝.19. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç. 18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╨╖╨░╨│╬┐╧ä╬┐╨▓╬║╤â ╧ü╨░╤ü╬║╨░╧ä╤ï╨▓╨░╤Ä╧ä ╨┤╬┐ ╧Ç╬┐╨╗╤â╤ç╨╡╨╜╨╕╤Å ╤ü╨╗╬┐╤Å ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╧ä ╨╕╨╜╬┐╨╣ë╨╕╨╜╬┐╨╣ ╬┐╧ä 0.03 ╨┤╬┐ 0.2 ╨╝╨╝.
20. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.19, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╬┐╨┤╨╜╬┐╬┐╤ü╨╜╬┐╨╡ ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╨╡ ╤ü╨╗╬┐╤Å ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨▓ ╧Ç╧ü╬┐╨┤╬┐╨╗╤î╨╜╬┐╨╝ ╨╜╨░╧Ç╧ü╨░╨▓╨╗╨╡╨╜╨╕╨╕ ╬┐╧ä 20 ╨┤╬┐ 1400% ╧Ç╨╡╧ü╨▓╬┐╨╜╨░╤ç╨░╨╗╤î╨╜╬┐╨│╬┐ ╧ü╨░╨╖╨╝╨╡╧ü╨░ ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨╕╧ä╤ü╤Å ╤ü╬┐ ╤ü╬║╬┐╧ü╬┐╤ü╧ä╤î╤Ä ╬┐╧ä 5 % ╨▓ ╤ü╨╡╬║. ╨┤╬┐ 40000 % ╨▓ ╤ü╨╡╬║. ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ ╬┐╧ä 50┬░╨í ╨┤╬┐ 225┬░╨í ╤ü ╧Ç╬┐╤ü╨╗╨╡╨┤╤â╤Ä╤ë╨╡╨╣ ╧ä╨╡╧ü╨╝╬┐╧å╨╕╬║╤ü╨░╤å╨╕╨╡╨╣ ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ 330-350┬░ ╨í ╨▓ ╧ä╨╡╤ç╨╡╨╜╨╕╨╡ 2-5 ╨╝╨╕╨╜╤â╧ä.20. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.19, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╬┐╨┤╨╜╬┐╬┐╤ü╨╜╬┐╨╡ ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╨╡ ╤ü ╨╗╬┐╤Å ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨▓ ╧Ç╧ü╬┐╨┤╬┐╨╗╤î╨╜╬┐╨╝ ╨╜╨░ ╧Ç╧ü╨░╨▓╨╗╨╡╨╜╨╕╨╕ ╬┐╧ä 20 ╨┤╬┐ 1400% ╧Ç╨╡╧ü╨▓╬┐╨╜╨░╤ç╨░╨╗╤ î╨╜╬┐╨│╬┐ ╧ü╨░╨╖╨╝╨╡╧ü╨░ ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨╕╧ä╤ü╤Å ╤ü╬ ┐ ╤ü╬║╬┐╧ü╬┐╤ü╧ä╤î╤Ä 5% ╨▓ ╤ü╨╡╬║. ╨┤╬┐ 40,000% ╨▓ ╤ü╨╡╬║. ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ ╬┐╧ä 50┬░╨í ╨┤╬┐ 225┬░╨í ╤ü ╧Ç ╬┐╤ü╨╗╨╡╨┤╤â╤Ä╤ë╨╡╨╣ ╧ä╨╡╧ü╨╝╬┐╧å╨╕╬║╤ü╨░╤å╨╕╨╡╨╣ ╧Ç ╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ 330-350┬░ ╨í ╨▓ ╧ä╨╡╤ç╨╡╨╜╨╕╨╡ 2 -5 ╨╝╨╕╨╜╤â╧ä.
21. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.19 ╨╕╨╗╨╕ ╧Ç.20, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╬┐╨┤╨╜╬┐╬┐╤ü╨╜╬┐╨╡ ╧ü╨░╤ü╧ä╤Å╨╢╨╡╨╜╨╕╨╡ ╤ü╨╗╬┐╤Å ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨▓ ╧Ç╬┐╧Ç╨╡╧ü╨╡╤ç╨╜╬┐╨╝ ╨╜╨░╧Ç╧ü╨░╨▓╨╗╨╡╨╜╨╕╨╕ ╬┐╧ä 20 ╨┤╬┐ 1400% ╧Ç╨╡╧ü╨▓╬┐╨╜╨░╤ç╨░╨╗╤î╨╜╬┐╨│╬┐ ╧ü╨░╨╖╨╝╨╡╧ü╨░ ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨╕╧ä╤ü╤Å ╤ü╬┐ ╤ü╬║╬┐╧ü╬┐╤ü╧ä╤î╤Ä ╬┐╧ä 5 %> ╨▓ ╤ü╨╡╬║. ╨┤╬┐ 40000 % ╨▓ ╤ü╨╡╬║. ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ ╬┐╧ä 50┬░╨í ╨┤╬┐ 225┬░╨í ╤ü ╧Ç╬┐╤ü╨╗╨╡╨┤╤â╤Ä╤ê╨╡╨╣ ╧ä╨╡╧ü╨╝╬┐╧å╨╕╬║╤ü╨░╤å╨╕╨╡╨╣ ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ 330-350┬░ ╨í ╨▓ ╧ä╨╡╤ç╨╡╨╜╨╕╨╡ 2-5 ╨╝╨╕╨╜╤â╧ä.21. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.19 ╨╕╨╗╨╕ ╧Ç.20, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨ ╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╬┐╨┤╨╜╬┐╬┐╤ü╨╜╬┐╨╡ ╧ü╨░╤ü╧ä╤Å╨╢ ╨╡╨╜╨╕╨╡ ╤ü╨╗╬┐╤Å ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗╨░ ╨▓ ╧Ç╬┐╧Ç╨╡╧ü╨╡╤ç ╨╜╬┐╨╝ ╨╜╨░╧Ç╧ü╨░╨▓╨╗╨╡╨╜╨╕╨╕ ╬┐╧ä 20 ╨┤╬┐ 1400% ╧Ç╨╡╧ü╨▓╬┐╨ ╜╨░╤ç╨░╨╗╤î╨╜╬┐╨│╬┐ ╧ü╨░╨╖╨╝╨╡╧ü╨░ ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨ ╕╧ä╤ü╤Å ╤ü╬┐ ╤ü╬║╬┐╧ü╬┐╤ü╧ä╤î╤╤ ╬┐╧ä 5%> ╨▓ ╤ü╨╡╬║. ╨┤╬┐ 40,000% ╨▓ ╤ü╨╡╬║. ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ ╬┐╧ä 50┬░╨í ╨┤╬┐ 225┬░╨í ╤ü ╧Ç ╬┐╤ü╨╗╨╡╨┤╤â╤Ä╤ê╨╡╨╣ ╧ä╨╡╧ü╨╝╬┐╧å╨╕╬║╤ü╨░╤å╨╕╨╡╨╣ ╧Ç ╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ 330-350┬░ ╨í ╨▓ ╧ä╨╡╤ç╨╡╨╜╨╕╨╡ 2 -5 ╨╝╨╕╨╜╤â╧ä.
22. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.20, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧ç╨░╧ü╨░╬║╧ä╨╡╧ü╨╕╨╖╤â╨╡╧ä╤ü╤Å ╬┐╨▒╤è╨╡╨╝╨╜╬┐╨╣ ╨┤╬┐╨╗╨╡╨╣ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 25 ╨┤╬┐ 94 %, 2722. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.20, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧ç╨░╧ü╨░╬║ ╧ä╨╡╧ü╨╕╨╖╤â╨╡╧ä╤ü╤Å ╬┐╨▒╤è╨╡╨╝╨╜╬┐╨╣ ╨┤╬┐╨╗╨╡╨╣ ╧Ç╧ü ╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 25 ╨┤╬┐ 94%, 27
╤â╨┤╨╡╨╗╤î╨╜╬┐╨╣ ╧Ç╬┐╨▓╨╡╧ü╧ç╨╜╬┐╤ü╧ä╤î╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0,1 ╨┤╬┐ 9,0 ╨╝╬║╨╝2/╨╝╬║╨╝~\ ╤ü╧ü╨╡╨┤╨╜╨╕╨╝ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡╨╝ ╨╝╨╡╨╢╨┤╤â ╧Ç╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 1 ,5 ╨┤╬┐ 50 ╨╝╬║╨╝, 85 ╤ü╧ü╨╡╨┤╨╜╨╡╨╣ ╧ç╬┐╧ü╨┤╬┐╨╣ ╬┐╨▒╤è╨╡╨╝╨╜╬┐╨╣ ╬┐╧ä 0,4 ╨┤╬┐ 30 ╨╝╬║╨╝.╨╜╬┐╨╣â╨┤╨╡╨╗╤î╨╜╬┐╨╣ ╧Ç╬┐╨▓╨╡╧ü╧ç╨╜╬┐╤ü╧ä╤î╤Ä ╧Ç╧ü╬┐╤ü╧ä ╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0.1 ╨┤╬┐ 9.0 ╨╝╬║╨╝ 2 / ╨╝ ╬║╨╝ ~ \ ╤ü╧ü╨╡╨┤╨╜╨╕╨╝ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡╨╝ ╨╝╨╡╨╢╨┤ ╤â ╧Ç╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 1, 5 ╨┤╬┐ 50 ╨╝╬║ ╨╝, 85 ╤ü╧ü╨╡╨┤╨╜╨╡╨╣ ╧ç╬┐╧ü╨┤╬┐╨╣ ╬┐╨▒╤è╨╡╨╝╨╜╬┐╨╣ ╬┐╧ä 0.4 ╨┤╬┐ 30 ╨╝╬║╨╝.
23. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.21, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧ç╨░╧ü╨░╬║╧ä╨╡╧ü╨╕╨╖╤â╨╡╧ä╤ü╤Å ╬┐╨▒╤è╨╡╨╝╨╜╬┐╨╣ ╨┤╬┐╨╗╨╡╨╣ ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 1 ╨┤╬┐ 35 %, ╤â╨┤╨╡╨╗╤î╨╜╬┐╨╣ ╧Ç╬┐╨▓╨╡╧ü╧ç╨╜╬┐╤ü╧ä╤î╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0,5 ╨┤╬┐ 20 ╨╝╬║╨╝2/╨╝╬║╨╝ ╤ü╧ü╨╡╨┤╨╜╨╕╨╝ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡╨╝ ╨╝╨╡╨╢╨┤╤â ╧Ç╤â╤ü╧ä╬┐╧ä╨░╨╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 0,5 ╨┤╬┐ 15 ╨╝╬║╨╝,23. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.21, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╨╝╨░╧ä╨╡╧ü╨╕╨░╨╗ ╧Ç╧ü╬┐╧ä╨╡╨╖╨░ ╧ç╨░╧ü╨░╬║ ╧ä╨╡╧ü╨╕╨╖╤â╨╡╧ä╤ü╤Å ╬┐╨▒╤è╨╡╨╝╨╜╬┐╨╣ ╨┤╬┐╨╗╨╡╨╣ ╧Ç╧ü ╬┐╤ü╧ä╧ü╨░╨╜╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 1 ╨┤╬┐ 35%, ╤â╨┤╨╡ ╨╜╬┐╨╣î╨╜╬┐╨╣ ╧Ç╬┐╨▓╨╡╧ü╧ç╨╜╬┐╤ü╧ä╤î╤Ä ╧Ç╧ü╬┐╤ü╧ä╧ü╨░╨╜ ╤ü╧ä╨▓╨░ ╧Ç╤â╤ü╧ä╬┐╧ä ╬┐╧ä 0.5 ╨┤╬┐ 20 ╨╝╬║╨╝ 2 / ╨╝╬║╨╝ ╤ü╧ü ╨╡╨┤╨╜╨╕╨╝ ╧ü╨░╤ü╤ü╧ä╬┐╤Å╨╜╨╕╨╡╨╝ ╨╝╨╡╨╢╨┤╤â ╧Ç╤â╤ü╧ä ╬┐╧ä╨░╨ ╝╨╕ ╨▓ ╬┐╨▒╤è╨╡╨╝╨╡ ╬┐╧ä 0.5 ╨┤╬┐ 15 ╨╝╬║╨╝,
90 сρедней χορдοй οбъемнοй οτ 0,1 дο 10 мκм.90 сρедней χορдοй οбъемнοй οτ 0.1 дο 10 мκм.
24. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╝╨╡╨╢╨┤╤â ╤ü╨╗╬┐╤Å╨╝╨╕, ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨╜╨╜╤ï╨╝╨╕ ╨╗╨╡╨╜╧ä╬┐╨╣ ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░, ╨╜╨░╨╝╨░╧ä╤ï╨▓╨╡╧ä╤ü╤Å ╤ü╧Ç╨╕╧ü╨░╨╗╤î ╨╕╨╖ ╨▓╬┐╨╗╬┐╬║╨╜╨░, ╧Ç╧ü╨╡╨╕╨╝╤â╤ê╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐ ╨╕╨╖ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ (╬ñ╬ª╨¡) ╤ü ╨│╨╡╬║╤ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╬┐╨╝, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╤ü24. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç. 18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╨╝╨╡╨╢╨┤╤â ╤ü╨╗╬┐╤Å╨╝╨╕, ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨ ╜╨╜╤ï╨╝╨╕ ╨╗╨╡╨╜╧ä╬┐╨╣ ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░, ╨╜╨░╨╝╨░ ╧ä╤ï╨▓╨╡╧ä╤ü╤Å ╤ü╧Ç╨╕╧ü╨░╨╗╤î ╨╕╨╖ ╨▓╬┐╨╗╬┐╬║╨╜╨░, ╧Ç╧ ü╨╡╨╕╨╝╤â╤ê╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐ ╨╕╨╖ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨ ░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ (╬ñ╬ª╨¡) ╤ü ╨│╨╡╬║╤ ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╬┐╨╝, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕ ╨╝ ╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╤ü
95 πеρφτορвинилэφиροм, с сοдеρжанием сοмοнοмеρа не δοлее 15%.95 πеρφτορвинилэφиροм, с сοдеρ жанием сοмοнοмеρа не δοлее 15%.
25. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧Ç╬┐╨▓╨╡╧ü╧ç ╧Ç╬┐╤ü╨╗╨╡╨┤╨╜╨╡╨│╬┐ ╤ü╨╗╬┐╤Å, ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨╜╨╜╬┐╨│╬┐ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨╣ ╨╗╨╡╨╜╧ä╬┐╨╣, ╨╜╨░╨╝╨░╧ä╤ï╨▓╨╡╧ä╤ü╤Å ╤ü╧Ç╨╕╧ü╨░╨╗╤î ╨╕╨╖ ╨▓╬┐╨╗╬┐╬║╨╜╨░, ╧Ç╧ü╨╡╨╕╨╝╤â╤ë╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐ ╨╕╨╖ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ (╬ñ╬ª╨¡) ╤ü ╨│╨╡╬║╤ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╬┐╨╝, ╨╕╨╗╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨░ ╤ü25. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç. 18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤╤╨╕╨╣╤╤╤╧ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╧Ç╬┐╨▓╨╡╧ü╧ç ╧Ç╬┐╤ü╨╗╨╡╨┤╨╜╨╡╨│╬┐ ╤ü╨╗╬┐╤Å , ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨╜╨╜╬┐╨│╬┐ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨╜╬┐╨╣ ╨╗╨ ╡╨╜╧ä╬┐╨╣, ╨╜╨░╨╝╨░╧ä╤ï╨▓╨╡╧ä╤ü╤Å ╤ü╧Ç╨╕╧ü╨░╨╗╤î ╨╕╨╖ ╨▓╬┐╨╗╬┐╬║╨╜╨░, ╧Ç╧ü╨╡╨╕╨╝╤â╤ë╨╡╤ü╧ä╨▓╨╡╨╜╨╜╬┐ ╨╕╨╖ ╤ ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡╨╜╨ ░ (╬ñ╬ª╨¡) ╤ü ╨│╨╡╬║╤ü╨░╧å╧ä╬┐╧ü╧Ç╧ü╬┐╧Ç╨╕╨╗╨╡╨╜╬┐╨╝, ╨╕╨ ╨╕ ╤ü╬┐╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╧ä╨╡╧ä╧ü╨░╧å╧ä╬┐╧ü╤ì╧ä╨╕╨╗╨╡ ╨╜╨░ ╤ü
100 πеρφτορвинилэφиροм, с сοдеρжанием сοмοнοмеρа не δοлее 15%.100 πеρφτορвинилэφиροм, с сοдеρ жанием сοмοнοмеρа не δοлее 15%.
26. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.18, ╨╕╨╗╨╕ ╧Ç.24, ╨╕╨╗╨╕ ╧Ç.25, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╧ü╨╝╬┐╬┐╨▒╧ü╨░╨▒╬┐╧ä╬║╨░ ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨╕╧ä╤ü╤Å ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ ╨▓╤ï╤ê╨╡ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╤ï ╧Ç╨╗╨░╨▓╨╗╨╡╨╜╨╕╤Å ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╨┤╨╗╤Å ╬┐╨▒╨╡╤ü╧Ç╨╡╤ç╨╡╨╜╨╕╤Å ╤ü╨▓╨░╧ü╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▓ ╨╝╨╡╤ü╧ä╨░╧ç ╧Ç╨╡╧ü╨╡╬║╧ü╤ï╧ä╨╕╨╣.26. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç. 18, ╨╕╨╗╨╕ ╧Ç.24, ╨╕╨╗╨╕ ╧Ç.25, ╬┐╧ä╨ ╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╧ü╨╝╬┐╬┐╨▒╧ü╨░ ╨▒╬┐╧ä╬║╨░ ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨╕╧ä╤ü╤Å ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡ ╧ü╨░╧ä╤â╧ü╨╡ ╨▓╤ï╤ê╨╡ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╤ï ╧Ç╨╗╨░╨▓ ╨╗╨╡╨╜╨╕╤Å ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░ ╨┤╨╗╤Å ╬┐╨▒╨╡╤ü╧Ç╨╡╤ç╨╡╨╜ ╨╕╤Å ╤ü╨▓╨░╧ü╬║╨╕ ╨╗╨╡╨╜╧ä╤ï ╨▓ ╨╝╨╡╤ü╧ä╨░╧ç ╧Ç╨╡╧ü╨╡╬║ ╧ü╤ï╧ä╨╕╨╣.
27. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.26, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╧ü╨╝╬┐╬┐╨▒╧ü╨░╨▒╬┐╧ä╬║╨░ 105 ╧Ç╧ü╬┐╨╕╨╖╨▓╬┐╨┤╨╕╧ä╤ü╤Å ╨▓ ╧ä╨╡╤ç╨╡╨╜╨╕╨╡ 2-30 ╨╝╨╕╨╜╤â╧ä.27. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.26, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤╤╨╕╨╣╤╨╕╨╣╤╤╧ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╧ä╨╡╧ü╨╝╬┐╬┐╨▒╧ü╨░╨▒╬┐╧ä╬║╨░ 105 ╧Ç╧ü╬┐╨╕╨╖╨ ▓╬┐╨┤╨╕╧ä╤ü╤Å ╨▓ ╧ä╨╡╤ç╨╡╨╜╨╕╨╡ 2-30 ╨╝╨╕╨╜╤â╧ä.
28. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.27, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐╨┤╨▓╨╡╧ü╨│╨░╨╡╧ä╤ü╤Å ╨┤╬┐╧Ç╬┐╨╗╨╜╨╕╧ä╨╡╨╗╤î╨╜╬┐╨╣ ╨▓╤ï╧ä╤Å╨╢╬║╨╡ ╬┐╧ä 50 ╨┤╬┐ 500%.28. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.27, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤╤╨╕╨╣╤╨╕╨╣╤╤╧ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╧Ç╧ü╬┐╧ä╨╡╨╖ ╧Ç╬┐╨┤╨▓╨╡╧ü╨│╨░╨╡╧ä╤ü╤Å ╨┤╬┐ SPECIFICATIONS 50 ╨┤╬┐ 500%.
29. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç.18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤ë╨╕╨╣╤ü╤Å ╧ä╨╡╨╝, ╤ç╧ä╬┐ ╨╜╨░ ╤ü╨╗╬┐╨╣, ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨╜╨╜╤ï╨╣ ╨╗╨╡╨╜╧ä╬┐╨╣ ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░, ╨╜╨░╨╜╬┐╤ü╨╕╧ä╤ü╤Å ╧ü╨░╤ü╧ä╨▓╬┐╧ü ╤ì╨╗╨░╤ü╧ä╬┐╨╝╨╡╧ü╨░ ╤ü ╧Ç╬┐╤ü╨╗╨╡╨┤╤â╤Ä╤ë╨╡╨╣29. ╨í╧Ç╬┐╤ü╬┐╨▒ ╧Ç╬┐ ╧Ç. 18, ╬┐╧ä╨╗╨╕╤ç╨░╤Ä╤╤╨╕╨╣╤╨╕╨╣╤╤╧ ╧ä╨ ╡╨╝, ╤ç╧ä╬┐ ╨╜╨░ ╤ü╨╗╬┐╨╣, ╬┐╨▒╧ü╨░╨╖╬┐╨▓╨░╨╜╨╜╤ï╨╣ ╨╗╨ ╡╨╜╧ä╬┐╨╣ ╨╕╨╖ ╧Ç╬┐╨╗╨╕╨╝╨╡╧ü╨░, ╨╜╨░╨╜╬┐╤ü╨╕╧ä╤ü╤Å ╧ü ╨░╤ü╧ä╨▓╬┐╧ü ╤ì╨╗╨░╤ü╧ä╬┐╨╝╨╡╧ü╨░ ╤ü ╧Ç╬┐╤ü╨╗╨╡╨┤╤â╤Ä ╤ë╨╡╨╣
110 ╧ä╨╡╧ü╨╝╬┐╬┐╨▒╧ü╨░╨▒╬┐╧ä╬║╬┐╨╣ ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨░╧ä╤â╧ü╨╡ ╬┐╧ä 20 -160┬░ ╨í. 110 ╧ä╨╡╧ü╨╝╬┐╬┐╨▒╧ü╨░╨▒╬┐╧ä╬║╬┐╨╣ ╧Ç╧ü╨╕ ╧ä╨╡╨╝╧Ç╨╡╧ü╨ ░╧ä╤â╧ü╨╡ ╬┐╧ä 20 -160┬░ ╨í.
PCT/RU1998/000260 1997-08-07 1998-08-07 Prosthesis for implantation and method for preparing the same WO1999007307A1 (en)

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RU97112837/14A RU2128024C1 (en) 1997-08-07 1997-08-07 Implanted hollow prosthesis and method of its manufacture

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2429407A (en) * 2005-06-04 2007-02-28 Vascutek Ltd Thin-walled vascular graft
US20090258958A1 (en) * 2007-10-04 2009-10-15 Ford Lawrence A Expandable TFE Copolymers, Methods of Making, and Porous, Expanded Articles Thereof
CN103977457A (en) * 2014-05-30 2014-08-13 国家纳米科学中心 Tubular tissue engineering scaffold and preparation method thereof
US9644054B2 (en) 2014-12-19 2017-05-09 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same
US9650479B2 (en) 2007-10-04 2017-05-16 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2203685C2 (en) * 2001-06-26 2003-05-10 Закрытое акционерное общество "Научно-производственный комплекс "Экофлон" Implant for restorative surgery
RU2207825C1 (en) * 2002-04-04 2003-07-10 Дьяков Валерий Евгеньевич Full-sclae implantable prosthesis
KR101779617B1 (en) * 2009-02-25 2017-09-18 오소본드 코포레이션 Anti-infective funtionalized surfaces and methods of making same

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU628911A1 (en) * 1977-02-08 1978-10-25 Предприятие П/Я Г-4299 Blood vessel prosthesis and method of manufacturing same
EP0146794A2 (en) * 1983-12-16 1985-07-03 B. Braun-SSC AG Method for the production of a artery prosthesis
EP0230635A2 (en) * 1985-12-24 1987-08-05 Sumitomo Electric Industries Limited Tubular prosthesis having a composite structure
WO1987005796A1 (en) * 1986-03-27 1987-10-08 Advanced Vascular Technologies, Inc. Vascular prostheses apparatus and method of manufacture
US4713070A (en) * 1978-11-30 1987-12-15 Sumitom Electric Industries, Ltd. Porous structure of polytetrafluoroethylene and process for production thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU628911A1 (en) * 1977-02-08 1978-10-25 Предприятие П/Я Г-4299 Blood vessel prosthesis and method of manufacturing same
US4713070A (en) * 1978-11-30 1987-12-15 Sumitom Electric Industries, Ltd. Porous structure of polytetrafluoroethylene and process for production thereof
EP0146794A2 (en) * 1983-12-16 1985-07-03 B. Braun-SSC AG Method for the production of a artery prosthesis
EP0230635A2 (en) * 1985-12-24 1987-08-05 Sumitomo Electric Industries Limited Tubular prosthesis having a composite structure
WO1987005796A1 (en) * 1986-03-27 1987-10-08 Advanced Vascular Technologies, Inc. Vascular prostheses apparatus and method of manufacture

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2429407A (en) * 2005-06-04 2007-02-28 Vascutek Ltd Thin-walled vascular graft
GB2429407B (en) * 2005-06-04 2009-10-14 Vascutek Ltd Thin-walled vascular graft
US7901446B2 (en) 2005-06-04 2011-03-08 Vascutek Limited Thin-walled vascular graft
US20090258958A1 (en) * 2007-10-04 2009-10-15 Ford Lawrence A Expandable TFE Copolymers, Methods of Making, and Porous, Expanded Articles Thereof
US8911844B2 (en) 2007-10-04 2014-12-16 W. L. Gore & Associates, Inc. Expanded TFE copolymers, method of making and porous, expanded articles thereof
US9040646B2 (en) * 2007-10-04 2015-05-26 W. L. Gore & Associates, Inc. Expandable TFE copolymers, methods of making, and porous, expanded articles thereof
US9193811B2 (en) 2007-10-04 2015-11-24 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, and porous, expanded articles thereof
US9593223B2 (en) 2007-10-04 2017-03-14 W. L. Gore & Associates, Inc. Expandable TFE copolymers, method of making, porous, expanded article thereof
US9650479B2 (en) 2007-10-04 2017-05-16 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same
US9988506B2 (en) 2007-10-04 2018-06-05 W. L. Gore & Associates, Inc. Dense articles formed tetrafluoroethylene core shell copolymers and methods of making the same
CN103977457A (en) * 2014-05-30 2014-08-13 国家纳米科学中心 Tubular tissue engineering scaffold and preparation method thereof
US9644054B2 (en) 2014-12-19 2017-05-09 W. L. Gore & Associates, Inc. Dense articles formed from tetrafluoroethylene core shell copolymers and methods of making the same

Also Published As

Publication number Publication date
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AU8892998A (en) 1999-03-01

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