WO1998033819A9 - Recepteurs cellulaires des adenovirus du sous-groupe c et des virus coxsackie du groupe b - Google Patents
Recepteurs cellulaires des adenovirus du sous-groupe c et des virus coxsackie du groupe bInfo
- Publication number
- WO1998033819A9 WO1998033819A9 PCT/US1998/001724 US9801724W WO9833819A9 WO 1998033819 A9 WO1998033819 A9 WO 1998033819A9 US 9801724 W US9801724 W US 9801724W WO 9833819 A9 WO9833819 A9 WO 9833819A9
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hcar
- protein
- mcar
- glycoprotein
- cell
- Prior art date
Links
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Abstract
Les molécules protéiques HCAR et MCAR sont, respectivement, des protéines humaines et des protéines de souris servant de récepteurs cellulaires pour les adénovirus des sérotypes 2 et 5 (sous-groupe C) et pour les virus Coxsackie du groupe B. L'invention se rapporte à des molécules d'ADN codant ces protéines ou codant des dérivés fonctionnels de ces dernières, à des cellules hôtes transformées par les molécules d'ADN et à des procédés permettant de produire les protéines recombinées et leurs dérivés. L'invention concerne aussi ces protéines, les fragments peptidiques de ces protéines qui correspondent à leurs domaines extracellulaires, ainsi que d'autres dérivés fonctionnels, en particulier les oligopeptides qui se lient au virus. Les protéines HCAR ou MCAR isolées ou des fragments ou des variants de ces dernières sont utilisées pour prévenir ou traiter les infections virales. L'expression de l'ADN précité dans des cellules qui ne possèdent pas ces récepteurs viraux rendent les cellules susceptibles d'être transformées par des vecteurs d'adénovirus portant des gènes de thérapie génique.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU61372/98A AU6137298A (en) | 1997-01-30 | 1998-01-30 | Cellular receptors for subgroup c adenoviruses and group b coxsackieviruses |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3698697P | 1997-01-30 | 1997-01-30 | |
| US60/036,986 | 1997-01-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1998033819A1 WO1998033819A1 (fr) | 1998-08-06 |
| WO1998033819A9 true WO1998033819A9 (fr) | 1998-12-03 |
Family
ID=21891817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1998/001724 WO1998033819A1 (fr) | 1997-01-30 | 1998-01-30 | Recepteurs cellulaires des adenovirus du sous-groupe c et des virus coxsackie du groupe b |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU6137298A (fr) |
| WO (1) | WO1998033819A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999015555A1 (fr) * | 1997-09-19 | 1999-04-01 | The General Hospital Corporation | Recepteurs car, molecules et procedes apparentes |
| WO2000029425A1 (fr) * | 1998-11-13 | 2000-05-25 | Kyowa Hakko Kogyo Co., Ltd. | Peptides actifs physiologiquement |
| GB0016791D0 (en) * | 2000-07-07 | 2000-08-30 | Novartis Ag | Organic compounds |
| EP1315416A2 (fr) * | 2000-09-07 | 2003-06-04 | Index Pharmaceuticals AB | Procede permettant d'obtenir un mammifere non humain susceptible de fournir un gene a mediation par adenovirus, |
| WO2002070744A2 (fr) * | 2001-03-07 | 2002-09-12 | Galapagos Genomics B.V. | Test de criblage de banque adénovirale destiné à des procédés et à des gènes régulateurs e2f, et compositions destinées au criblage de composés |
| AU2003213164A1 (en) * | 2002-02-19 | 2003-09-09 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of | Mutated constitutively active nuclear orphan receptor |
| US8017344B2 (en) * | 2004-04-28 | 2011-09-13 | Eisai R&D Management Co., Ltd. | Methods for detecting Th1 cells |
| US7608413B1 (en) | 2005-03-25 | 2009-10-27 | Celera Corporation | Kidney disease targets and uses thereof |
-
1998
- 1998-01-30 WO PCT/US1998/001724 patent/WO1998033819A1/fr active Application Filing
- 1998-01-30 AU AU61372/98A patent/AU6137298A/en not_active Abandoned
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