Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
  • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
  • A61B6/08—Auxiliary means for directing the radiation beam to a particular spot, e.g. using light beams

Definitions

• the present invention relates to medical imaging systems and in particular to a method and apparatus for aligning an imaging device relative to a patient's body.
• the invention is particularly, but not exclusively, applicable to the positioning of x-ray apparatus.
• the x-ray film When taking an x-ray of a patient, it is important to correctly position the x-ray source relative to the patient's body.
• the x-ray film is placed beneath a table on which the patient lies, with an ionization chamber positioned between the patient and the film.
• the vertical distance of the x-ray source above the patient is set by the operator.
• the x-ray source can also be moved by the operator in a horizontal plane.
• a known system for enabling accurate positioning of the x-ray source in the horizontal plane involves the projection of a beam of light from a light source onto a patient's body.
• the light source is positioned adjacent to the x-ray source and is fixed relative thereto.
• a x-ray radiation translucent mirror is used to direct the light beam onto the patient's body along the path taken by the x-ray beam.
• the operator Prior to taking the x- ray, the operator positions the x-ray source using the light beam as a guide. Whilst in theory this system improves x-ray source alignment, in practice, regular checks must be carried out on the x-ray apparatus to ensure that the light source does not become misaligned relative to the x-ray source.
• apparatus for aligning an imaging device relative to a human or animal body to enable an image of an operator selected anatomical region to be obtained, the apparatus comprising: a plurality of light reflective markers for attachment to respective anatomical landmarks of the body, which landmarks mark out said anatomical region; an image sensor arranged in use to view at least a portion of the body including attached reflective markers; a light source arranged in use to illuminate attached reflective markers; and an image processing computer for receiving image data from the image sensor, the computer being arranged: a) to store or access a database of standard patient records including, for each of a plurality of anatomical regions, a locating position for the imaging device relative to the positions of said anatomical landmarks; b) to select an appropriate record from the database using operator input data for the patient to be imaged; c) to select from the selected record a relative locating position for the imaging device using operator input data identifying the anatomical region to be imaged; d) to determine from said image data the
• the number of reflective markers required depends upon the particular area to be imaged. Typically however, a relatively small number of markers are used, e.g. between two and five.
• the image sensor comprises at least one CCD camera.
• the image sensor comprises a pair of CCD cameras which are spaced apart so as to enable a three dimensional image of a patient's body to be obtained.
• the resulting three dimensional image can be used in order to provide position information in three dimensions.
• the computer may be arranged to store focus information defining a preferred focal distance for each anatomical region.
• the three dimensional position information may be used to manually, or automatically set the distance of the imaging device from the patient's body.
• three dimensional rendering techniques can be applied to allow a 3-D visual image of the patient to be presented to an operator, maximising the information available to the operator.
• said image sensor is positioned adjacent to said light source and the light reflective markers are retro-reflective markers which tend to reflect light in the direction of the light source and the image sensor.
• the image sensor is arranged to generate image data in which areas without reflective markers are identified as black with the reflective markers being identified as light spots. This may be achieved by appropriately setting the aperture of the image sensor or by shuttering the image sensor at an appropriately high speed. Alternatively, or in addition, image data generated by the image sensor may be applied to a variable gain amplifier.
• the light source comprises a flash lamp which may be operated in synchronisation with an image sensor shutter.
• the imaging device which is aligned by the present invention is a x-ray imaging system.
• the image sensor is rigidly secured to the x- ray generating apparatus so that alignment of the image sensor relative to the x-ray tube can be accurately maintained.
• the image processing computer comprises a video display unit.
• the computer may be arranged to superimpose the determined positions of the light reflective markers on the display.
• the locating position of the imaging device may also be displayed.
• the apparatus of the above first aspect of the present invention may comprise positioning means, coupled to said computer, for automatically positioning the imaging means
• the image processing computer may also be arranged to locate the imaging device at the correct focal distance, e.g. using said three-dimensional position information and using a calibration frame containing permanent markers positioned strategically on the x-ray table.
• a method of aligning an imaging device relative to a human or animal body to enable an image of a selected anatomical region to be obtained comprises the steps of: attaching a plurality of light reflective markers to anatomical landmarks of the body; illuminating the body and the reflective markers with light; detecting light reflected from the reflective markers with an image sensor; selecting from a database of standard patient records, a record appropriate to the patient or animal to be imaged, each record including, for each of a plurality of anatomical regions, a locating position for the imaging device relative to the positions of said anatomical landmarks; selecting from the selected record a set of relative positions using operator input data identifying the anatomical region to be imaged; using the selected relative position data and the determined positions of the reflective markers to determine the actual position at which the imaging device should be located in order to obtain a desired image; and positioning the imaging device at said determined position.
• an imaging aligning system for aligning anobject to be imaged with a source of imaging radiation to which the object is exposed for creating an image of the object
• said image aligning system comprising: a first radiation source for generating an incident alignment radiation signal, a plurality of reflective markers adapted to be located at predetermined locations on the object to be imaged, reflected alignment radiation means for receiving reflected alignment radiation from the reflective markers disposed on said object, processing means coupled to the radiation source mans for providing positional information of said reflective markers relative to said object and to said source of imaging radiation, said processing means being coupled to a database of object data identifying the position for locating said source of imaging radiation relative to said object for centering said source relative to said reflective markers for exposing said object to said source of imaging information.
• apparatus for obtaining a desired image of an object, said apparatus having a source of imaging radiation to which the object is exposed and imaging means for obtaining an image of the object exposed to said radiation source, said object to be exposed having a plurality of markers defining an area of said object to be imaged, said apparatus including an aligning system stated in the above further aspect of the invention for facilitating alignment of the source of imaging radiation and said markers in order to obtain said desired image.
• a method of obtaining a desired image of an object using apparatus having a source of radiation for exposed the object to the radiating and imaging means for obtaining an image of said exposed object comprising the steps of: disposing locating reflective markers on predetermined locations of said object, transmitting a first incident signal from a signal source towards said object, collecting reflected signals from said markers, said reflected signals being indicative of the position of said markers, processing said reflected signals by comparing said marker location information with predetermined stored information from a database providing a relative position of the object to be imaged, determining the position of said reflective markers relative to said source of radiation, and aligning the source with the reflective markers in which imaging of said object produces said desired image.
• Figure 1 is a bird's-eye view of a supine patient to be x-rayed with reflective anatomical landmarks disposed at certain positions for imaging the anterio-posterior lumbar spine;
• Figure 2 is a perspective view of the patient of
• Figure 3 is a perspective view of the patient with three reflective anatomical markers disposed for assisting in imaging a lateral view of the lumbar spine;
• Figure 4 illustrates a x-ray apparatus, incorporating a positioning system according to an embodiment of the present invention.
• FIG. 5 is a block diagram of the system of Figure 4.
• Figure 1 a bird's-eye view of a patient 10 lying on the table 12 of a x-ray system.
• Figure 2 shows a perspective view of the patient .
• Three retro-reflective markers 14 are located on specific parts of the patient's body by an operator, usually a radiographer. The exact location of these markers depends upon the anatomical region to be imaged.
• Figure 1 where the anterio-posterior lumbar spine is to be imaged, so the markers are positioned on the sternal notch and both anterior superior iliac spine.
• the markers When it is desired to obtain a lateral image of the lumbar spine, the markers are positioned, as shown in Figure 3, on the axilla, the anterior superior iliac spine, and the posterior superior iliac spine.
• the required positions of the markers are readily located by an experienced radiographer.
• Each of the retro-reflective markers 14 comprise a mirrored surface coated with glass micro-spheres (manufactured by 3M Corporation) which act as prisms to reflect incident light back towards its source.
• the markers reflect light received from a light source mainly back towards that light source and thus are highly efficient where a light detector, used to detect reflected light, is placed adjacent to the light source.
• Figure 4 illustrates a combined x-ray apparatus and positioning system, generally indicated by reference numeral 16, which is arranged to use positional information from the reflecting markers 14 to accurately align the x-ray tube apparatus, generally indicated by reference numeral 18, to the selected anatomical region of the patient's body.
• X-ray radiation is produced by a x-ray source 20 (shown in broken outline) contained within a lead-lined housing 22. X-rays from the source 20 are collimated within a channel 24 through which the x-ray radiation beam exits.
• the x-ray apparatus and positioning system 16 is adjustably mounted on a support 26 such that the height of the apparatus 16 above the patient 10 can be varied. The mounting arrangement also allows the x-ray apparatus 16 to be moved in a horizontal plane for alignment with the patient.
• a x-radiation translucent mirror 28 Contained within the x-ray apparatus channel 24 is a x-radiation translucent mirror 28, oriented at an angle of 45° to the vertical.
• the mirror 28 allows x-ray radiation to pass freely therethrough towards the patient and the film but presents a reflecting surface to reflected light.
• an infra-red strobe 30 Positioned inside the x-ray apparatus 16 is an infra-red strobe 30 which can generate relatively short pulses of light (i.e. 50 pulses per second at a wavelength of 980mm) .
• Light from strobe 30 is reflected from the patient 10 and from the reflective markers 14 is reflected towards the x-ray apparatus 14 and the strobe 30 due to the retro-reflective nature of the markers 14.
• Reflected light entering the channel 24 is reflected by the mirror 28 towards a side-wall 32 of the channel 24.
• a charge coupled camera 33 having camera elements 34,36 are mounted in this side wall for receiving the reflected radiation. Cameras elements 34,36 are spaced apart in the vertical direction such that they receive reflective light beams 38,40 from markers 14 located horizontally spaced apart positions on the patient 10.
• an ionisation chamber 42 Positioned beneath the table 12 is an ionisation chamber 42 which forms part of a known type automatic exposure device (AED) .
• AED automatic exposure device
• the AED monitors the x-ray beam transmitted through the area of the patient's body under examination.
• ionisation chamber timers the AED terminates the exposure when a sufficient quantity of radiation has been received to produce a radiographic image of the required density.
• the AED exercises accurate control on the quantity of radiation provided that the positioning of the patient is accurate in relation to the site of the ionisation chamber.
• the film is placed beneath the ionisation chamber in a mount 44 and receives the radiation which has been transmitted through the patient and AED.
• FIG. 5 depicts the block diagram which shows schematically the image processing system, generally indicated by reference numeral 46, which is used to analyse the outputs of the two CCD camera elements 34,36 to determine alignment information for the x-ray apparatus 16.
• the image processing system 46 includes a video processor 48 for capturing visual information and a computer for analysing the captured information. After a predetermined time interval following activation of the strobe 30, the video processor 48 captures an image frame from each of the elements 34,36. The video processor 48 looks for transitions from dark to light in these frames and identifies any such transitions as the presence of light reflecting markers 14. The video processor scans each horizontal line of the captured image frames from left to right and identifies transitions from dark to light.
• transitions are located at approximately the same position on two consecutive horizontal lines, these transitions are grouped together and are identified as the site of a reflecting marker.
• the elements 34,36 are provided with respective shutters (not shown) which open for a very short time interval during the strobe exposure. Typically, the shutters open for 1/1250 of a second.
• the output of each CCD element is also applied to a variable gain amplifier (not shown) within the video processor 48 the gain of which is adjusted so that the intensity produced by the reflective markers 14 is set as a 'normal' intensity. This set-up generates image data where the reflective markers 14 show up as bright spots while remaining areas are black.
• the system may be further optimised by minimising the background light levels in the room containing the x-ray apparatus .
• the resulting position data which defines the absolute position of the retro-reflective markers 14 relative to the patient 10 and the x-ray apparatus 16, is delivered from the video processor to the computer 50.
• the computer 508 contains a database of standard patient records. The patients selected for the database cover a range of heights and weights, and each record contains anatomical position data for each of a number of anatomical regions. This anatomical data defines the position at which the x-ray apparatus 16 should be positioned for the X-ray to be centred upon the required anatomical region, relative to the positions of the reflecting markers 14 on the anatomical landmarks.
• the radiographer uses a keyboard 52 to enter the height, weight and identification of the patient 10 to be imaged.
• the computer 50 selects the appropriate record from the stored database.
• the radiographer then also selects the anatomical region of interest and the appropriate data is extracted from the selected record.
• the computer is able to calculate the actual locating position. This positional information can either be displayed to the operator who can then manually position the x-ray apparatus or the positional information can be fed to automatic x-ray apparatus adjustment means for automatically repositioning the apparatus 16.
• the system 46 optionally contains a display monitor 54 for displaying image data generated by one of the CCD cameras 34,36.
• the cameras 34,36 may be arranged to generate normal continuous image data for display on the monitor 54, the cameras only being shuttered for a relatively short time period to obtain reflective marker position information. Once this position information has been obtained, it can be overlaid on the image of the patient's body on the display. This allows the operator to visually confirm the correct identification of the reflective markers 14 before automatic alignment of the x-ray apparatus occurs.
• the computer may be arranged to overlay the determined locating position of the x-ray apparatus on the display.
• a first marker would be placed 2.5cm above the superior aspect of the patella, a second marker 2.5cm below the tibial tuberosity, and third and fourth markers on the lateral and medial borders adjacent to the apex of the patella.
• a first marker would be placed 2.5cm above the upper border of the knee on the medial side, and a second marker placed 2.5cm below the apex of the patella on the medial side.
• patient movement can be monitored visually, thus allowing the operator to correct patient position relative to any movement. This function therefore provides an assessment of the correctness of positioning before the x-ray exposure has been made. Monitoring of patient movement continues until the exposure has been completed.
• the x-ray system and positioning apparatus can be used to image an animal body and the light source used could be replaced by an infra-red source with an infra-red camera.
• the positioning system may be used with any other suitable medical imaging system where alignment of the source of radiation with the part of the patient to be imaged is required.

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• 1996
  • 1996-11-13 GB GBGB9623575.9A patent/GB9623575D0/en active Pending
• 1997
  • 1997-11-13 AT AT97912306T patent/ATE359028T1/de not_active IP Right Cessation
  • 1997-11-13 ES ES97912306T patent/ES2286829T3/es not_active Expired - Lifetime
  • 1997-11-13 JP JP52228198A patent/JP3902239B2/ja not_active Expired - Fee Related
  • 1997-11-13 US US09/297,969 patent/US6267503B1/en not_active Expired - Fee Related
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  • 1997-11-13 DE DE69737604T patent/DE69737604T2/de not_active Expired - Fee Related
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  • 1997-11-13 AU AU49549/97A patent/AU732859B2/en not_active Ceased
  • 1997-11-13 WO PCT/GB1997/003045 patent/WO1998020795A1/en active IP Right Grant

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