WO1998018439A1 - Compositions permettant d'attenuer les odeurs corporelles et l'exces de moiteur - Google Patents

Compositions permettant d'attenuer les odeurs corporelles et l'exces de moiteur Download PDF

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Publication number
WO1998018439A1
WO1998018439A1 PCT/US1997/019262 US9719262W WO9818439A1 WO 1998018439 A1 WO1998018439 A1 WO 1998018439A1 US 9719262 W US9719262 W US 9719262W WO 9818439 A1 WO9818439 A1 WO 9818439A1
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WO
WIPO (PCT)
Prior art keywords
composition
odor
skin
present
cyclodextrin
Prior art date
Application number
PCT/US1997/019262
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English (en)
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WO1998018439A9 (fr
Inventor
Liezl Gonzales Peterson
Patricia Alison Lafleur
Original Assignee
The Procter & Gamble Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/736,838 external-priority patent/US5780020A/en
Priority claimed from US08/739,091 external-priority patent/US5885599A/en
Priority to BR9712449-4A priority Critical patent/BR9712449A/pt
Priority to IL12957197A priority patent/IL129571A0/xx
Priority to JP52061298A priority patent/JP2002515890A/ja
Priority to IDW990256D priority patent/ID23973A/id
Application filed by The Procter & Gamble Company filed Critical The Procter & Gamble Company
Priority to AU49183/97A priority patent/AU4918397A/en
Priority to EP97911917A priority patent/EP0954276A1/fr
Priority to CA002269471A priority patent/CA2269471A1/fr
Publication of WO1998018439A1 publication Critical patent/WO1998018439A1/fr
Publication of WO1998018439A9 publication Critical patent/WO1998018439A9/fr
Priority to NO991895A priority patent/NO991895L/no

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins

Definitions

  • Body odor is most commonly caused by fatty acids on skin and by malodors from microbial sources.
  • the human skin is naturally populated with numerous micro-organisms which are nourished by various skin secreted substances (eccrine and apocrine sweat, and sebum), skin cell debris, breakdown products of the skin and the organisms themselves.
  • These unpleasant body odors are mainly organic molecules which have different structures and functional groups, such as amines, acids, alcohols, aldehydes, ketones, phenolics, polycyclics, indoles, aromatics, polyaromatics, etc. They can also be made up of sulfur- containing functional groups, such as, thiol, mercaptan, sulf.de and/or disulfide groups.
  • deodorant compositions aimed at combating controlling odor associated with skin secretions, which have been described in the chemical and cosmetic literature, include emulsion sticks or suspensoid sticks, aerosols, roll-ons, pads, pump sprays, and even soap bars. These known deodorants attempt to control odor through a variety of means. For instance, U.S. Patent No. 5,525,331, to Betts, issued June 11, 1996, discloses compositions which inhibit the growth of micro-organisms in the body-secretions. Deodorants may also include antibacterial compounds which help destroy/control the amount of bacteria present on skin, thereby minimising odor produced via bacterial metabolism of skin secretions.
  • Zeolites are known odor absorbers. However, these solid odor absorbers, in addition to known activated charcoal odor absorbers, lose functionality when wet. Therefore, when wetted by body fluids or when carried in an aqueous solution, these odor absorbers are not preferred as they lose their desired odor absorbent characteristics. Furthermore, zeolites can cause "harsh” feel if too much is deposited onto the skin.
  • an improved odor and moisture absorbing composition which is essentially free of irritating ingredients such as perfumes or astringent antiperspirants and which is safe and effective for use on the entire body. More particularly, there is a need for a convenient composition which is left on the skin and is capable of absorbing a broad spectrum of body odors and excess moisture that are not fully suppressed by the aforementioned means.
  • a composition which is left on the skin, which incorporates odor absorbing, uncomplexed cyclodextrins; highly effective moisture absorbing ingredients; and a powder carrier.
  • a particular advantage of the present invention is the ability to provide convenient, non-irritating odor and moisture protection when applied to occluded skin areas such as the pelvic region, the external vagina, the panty-area, the bra-line, and skin-folds, which may be very sensitive.
  • the aforementioned benefits may be delivered in a powder carrier which also optionally delivers skin aid benefits to the user such as protection and/or moisturization.
  • the present invention relates to a perfume-free powder, odor absorbing composition, which is safe for use on skin comprising from about 0.1% to about 25%, by weight of the composition, of uncomplexed cyclodextrin; and a powder carrier.
  • the present invention also relates to a powder odor and moisture absorbing composition which additionally comprises from about 5% to about 60%, by weight of the composition, of a highly effective moisture absorber.
  • the compositions of the present invention may also contain additional odor controlling agents selected from the group consisting of zeolites, activated charcoal, sodium bicarbonate, antimicrobial agents, and antiperspirants.
  • the present invention also relates to the use of the aforementioned compositions in reducing body odor and excess moisture on occluded skin sites.
  • the present invention relates to a perfume-free, dry powder, odor absorbing, and optionally moisture absorbing composition.
  • the present invention also relates to the use of the aforementioned powder composition in reducing body odor and excess moisture from occluded skin sites wherein the powdered composition is applied to occluded skin.
  • the composition can be applied to occluded skin directly as a spray, shaken from a bottle or canister and applied by hand, or applied via wipe which is dry.
  • composition of the present invention comprises dry ingredients preferably having particle sizes of from about 1 micron to about 100 microns; more preferred from about 1 micron to about 60 microns; and most preferred from about 1 micron to about 20 microns.
  • particle size refers to the largest dimension of the particle and to the ultimate (or primary) particles.
  • occluded skin refers to regions of a human body covered by undergarments, such as the pelvic area, panty-area, and bra-line; and skin-folds or intertriginous regions, where there is continuing skin to skin contact.
  • body fluids includes eccrine sweat, apocrine sweat, sebum, build up of sensible moisture from transepidermal water loss, vaginal discharge, urine, and mixtures thereof.
  • excess moisture means an undesirable and/or unhealthy level of body fluids deposited on the human skin.
  • body odor means odors which are generated as a result of the natural functioning of a human body. Such odors include, but are not limited to odors produced by microorganisms of the human skin (i.e. bacterial decomposition of skin secretions), urine, or vaginal discharge, and mixtures thereof.
  • the term "entire body” means the entire external surface of human or mammalian skin.
  • vaginal odor relates specifically to those body odors which emanate from the pelvic region of a woman, particularly the vagina and the panty area.
  • cyclodextrin includes any of the known cyclodextrins such as unsubstituted cyclodextrins containing from six to twelve glucose units, especially alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin and/or their derivatives and/or mixtures thereof.
  • uncomplexed cyclodextrin as used herein means that the cavities within the cyclodextrin in the composition of the present invention should remain essentially unfilled prior to application to skin in order to allow the cyclodextrin to absorb various odor molecules when the composition is applied to the skin.
  • cyclodextrins for use in the present invention are alpha-cyclodextrin, beta- cyclodextrin, gamma-cyclodextrin and/or their derivatives. More preferred are beta cyclodextrin, hydroxypropyl alpha-cyclodextrin, hydroxypropyl beta-cyclodextrin, methylated-alpha-cyclodextrin or methylated-beta-cyclodextrin. Most preferred is beta- cyclodextrin.
  • cyclodextrins absorb body odors more broadly by complexing with a wider range of odoriferous molecules having a wider range of molecular sizes.
  • the levels of cyclodextrin are from about 0.1% to about 25%, preferably from about 1% to about 20%, more preferably from about 2% to about 15%, most preferably from about 3% to about 10%, by weight of the composition.
  • Cyclodextrins having small particle sizes aid in providing higher cyclodextrin surface availability for odor absorption and therefore are preferred.
  • the particle size refers to the largest dimension of the particle and to the ultimate (or primary) particles.
  • Small particle cyclodexrins of this invention are those having a particle size of less than about 12 microns, preferably less than about 10 microns, and more preferably less than about 5 microns.
  • a more complete description of the cyclodextrins, cyclodextrin derivatives, and cyclodextrin particle sizes useful in the present invention can be found in U.S. Patent No. 5,429,628, Trinh et al., issued July 4, 1995, which is incorporated herein by reference in its entirety.
  • the cyclodextrins and other optional components useful in the present invention should be dispersed in a pharmaceutically-acceptable powder carrier for convenient, uniform application and disbursement onto the skin.
  • pharmaceutically-acceptable means a powder suitable for topical use on the skin without undue toxicity, irritation, allergic response, and the like.
  • the powder carrier also helps prevent any solubilized cyclodextrin from washing away from the desired skin contact.
  • Powder carriers useful in the present invention include powders known in the art to be safe for human skin.
  • Such powders include but are not limited to cornstarch (topical starch), talc, rice starch, oat starch, tapioca starch, microcrystalline cellulose (for example Avicel®), aluminum starch octenyl succinate (sold by National Starch & Chemical Co. as Dry Flo® Pure, Dry Flo® XT, and/or Dry Flo® PC), kaolin, and mixtures thereof.
  • cornstarch topical starch
  • talc rice starch
  • oat starch tapioca starch
  • microcrystalline cellulose for example Avicel®
  • aluminum starch octenyl succinate sold by National Starch & Chemical Co. as Dry Flo® Pure, Dry Flo® XT, and/or Dry Flo® PC
  • kaolin kaolin
  • the powder carrier of the present invention will comprise from about 10% to about 95%, preferably from about 15% to about 80%, more preferably from about 25% to about 50%, by weight of the composition.
  • HIGHLY EFFECTIVE MOISTURE ABSORBERS Highly effective moisture absorbers may optionally be included in the present invention to aid in reducing excess moisture on occluded skin. Highly effective moisture absorbers also increase the flowability (the ability to flow without caking due to moisture) of the compositions of the present invention.
  • highly effective moisture absorbers refers to silicas (silicone dioxide), silicates or carbonates wherein the silicates and carbonates are formed by reaction of a carbonate or silicate with the alkali (IA) metals, alkaline earth (IIA) metals, or transition metals.
  • Preferred highly effective moisture absorbers are calcium silicate, amorphous silicas, calcium carbonate, magnesium carbonate, or zinc carbonate, and mixtures thereof.
  • Synthetic versions of the highly effective moisture absorbers, particularly in regards to silicas and silicates due to safety risks related to crystalline silica. Synthetic versions are formed by controlled chemical reactions in a manufacturing process rather than using a natural, mined version of these compounds which is then further refined.
  • Synthetic carbonates useful in the present invention can be obtained from various suppliers such as Mallinckrodt or Whittaker, Clark, and Daniels.
  • Examples of synthetic calcium silicates useful in the present invention are Hubersorb® 250 or Hubersorb® 600 available from J.M. Huber.
  • the highly effective moisture absorbers comprise from about 5% to about 60%; more preferred, from about 10% to about 50%; and most preferred, from about 20% to about 40% by weight of the total compo
  • compositions of the present invention may comprise zeolites, carbon odor-controlling agents, sodium bicarbonates, antimicrobial agents and/or antiperspirant ingredients for added body odor control.
  • zeolites refers to non-fibrous zeolites. When included in the present invention, zeolites may be present from about 0.1% to about 25%, preferably from about 1% to about 15%, by weight of the composition. A detailed description of zeolites useful in the present invention is found in U.S. Patent No. 5,429,628, Trinh et al., issued July 4, 1995, incorporated herein by reference in its entirety.
  • Carbon odor-controlling agents described in U.S. Patent No. 5,429,628 may be used in the present invention at a level of from about 0.1% to about 25%, by weight of the composition.
  • sodium bicarbonate is known in the art for its use as an odor absorber.
  • An example of sodium bicarbonate and its use as an underarm deodorant is found in U.S. Patent No. 4,382,079, to Marschner, issued May 3, 1983, which is incorporated herein in its entirety by reference.
  • sodium bicarbonate may be present from about 0.1% to about 50%, by weight of the composition.
  • the antimicrobial agents of the present invention are selected from a group consisting of antibacterial agents, antifungal agents, and mixtures thereof. Antimicrobial agents help destroy and/or control the amount of bacteria and or fungi present on the skin.
  • Preferred antimicrobial agents are zinc phenolsulfonate, zinc oxide, triclosan, Zelec® AM by DuPont, zinc ricinoleate, zinc undecylenate, and mixtures thereof. More preferred are zinc phenolsulfonate, zinc oxide, and triclosan. Triclosan is available from Ciba-Geigy as Irgasan DP-300. Examples of antimicrobial agents useful in the present invention are found in the Cosmetic Bench Reference. 1994 Edition, page 10, which is incorporated herein by reference. When included in the present invention, the antimicrobials are at a level of from about 0.01% to about 25%. Preferably from about 0.1% to about 10%, by weight of the present composition.
  • antiperspirant ingredients When used on the underarms, antiperspirant ingredients may be included in the present invention. Examples of antiperspirants known in the art are found in the Cosmetic Bench Reference. 1994 Edition, page 13, which is incorporated herein by reference. When included in the present invention, antiperspirants may be present from about 0.1% to about 25%, by weight of the composition.
  • compositions of the present invention also optionally include skin aids.
  • skin aids refers to skin protectants, emollients, and moisturizers.
  • Skin protectants useful in the present invention are found in the Cosmetic Bench Reference. 1994 Edition, page 53; and the Monograph on Skin Protectant Drug Products for Over-the-Counter Human Use, 21 CFR 347.
  • Preferred skin protectants are corn starch, kaolin, mineral oil, sodium bicarbonate, dimethicone, zinc oxide, colloidal oatmeal, and mixtures thereof.
  • the skin protectants comprise from about 0.1% to about 80%, preferably from about 0.1% to about 30%, most preferably from about 0.1% to about 10%, by weight of the composition.
  • Emollients and moisturizers useful in the present invention can be found in the Cosmetic Bench Reference. 1994 Edition, pages 27-32 and 46-48, incorporated herein by reference.
  • Preferred emollients and moisturizers are tocopherol, tocopheryl acetate, aloe, vegetable oils, mineral oil, petrolatum, jojoba oil, and mixtures thereof. More preferred are encapsulated or spray/freeze dried emollients. The use of spray/freeze dried or encapsulated emollients keeps the emollients protected in the powder carrier until they are released through shearing (such as rubbing against undergarments or clothes) or through contact with skin moisture.
  • emollients/moisturizers comprise from about 0.1% to about 50%, preferably from about
  • compositions may optionally comprise slip compounds.
  • slip compounds refers to compounds which have unique structures which provide enhanced slip/lubrication characteristics of powders and/or reduced skin to skin friction between intertriginous skin sites.
  • Slip compounds of the present invention include polyethylene; nylon; polytetra- fluoroethylene; silica which is in the form of microspheres, ellipsoids, barrel-shapes, and the like; mica, silicone (e.g. dimethicone) and metallic stearates (e.g. zinc stearate); and mixtures thereof.
  • Preferred slip compounds are silicas which are in the form of microspheres, ellipsoids, barrel-shapes, and the like.
  • Silica ellipsoids useful in the present invention are available from DuPont as ZELEC® Sil.
  • Silica microspheres are available from KOBO as MSS-500, MSS 500/3, MSS-500/H, MSS-500/3H, MSS-500/N, and MSS-500/3N. Additionally, it is preferred that some of the silica of the present invention be fumed silica for increased flowability of the powder in addition to enhancing the slip characteristics. Fumed silica is available from Cabot Corporation (Cab-O-Sil®) and from Degussa (Aerosil®).
  • the slip compounds When present in the compositions of the invention, the slip compounds comprise from about 0.1% to about 35% , preferably from about 1% to about 10%, by weight of the composition.
  • BINDERS The present invention may optionally also include dry or wet binders to help promote adhesion of the powder and active ingredients to the skin. Binders useful in the present invention are found in the Cosmetic Bench Reference. 1994 Edition, pages 13-14, which is incorporated herein by reference. Preferred binders are calcium stearate, zinc stearate, isopropyl myristate, magnesium myristate, silicone, and mixtures thereof. More preferred are zinc stearate, dimethicone, and mixtures thereof.
  • the binders When included in the composition, the binders are at a level of from about 0.1% to about 25%, preferably from about 1% to about 15%, by weight of the composition.
  • ANTI-PRUR ⁇ IC AGENTS Anti-pruritic agents such as those known in the art may be included in the compositions of the present invention. Examples of anti-pruritic agents useful in the present invention are Magnesium-L-Lactate, hydrocortisone, hydrocortisone acetate, and colloidal oatmeal. A description of anti-pruritic agents are found in the Handbook of Non Prescription Drugs. 10th Edition, p. 529, 1993; which is incorporated herein by reference. When included in the composition, anti-pruritic agents may be present from about 0.1% to about 40%, by weight of the composition..
  • COLORANTS Colorants and dyes can be optionally added to the odor absorbing compositions for visual appeal and performance impression. Colorants suitable for use in the present invention are found in the Cosmetic Bench Reference. 1994 Edition, pages 21-22, which is incorporated herein by reference
  • compositions of the present invention are prepared by the following steps: creating a mixture by mixing cyclodextrin, highly effective moisture absorbers (if present), and optional ingredients in a powder carrier via a commercially available mixer such as a vee-blender, double cone blender, or ribbon blender until the mixture is uniform; and creating a reduced size mixture using a commercially available size reduction technique such as hammer milling, impact milling, ball milling, or fluid energy milling until the desired particle size distribution is achieved.
  • a commercially available mixer such as a vee-blender, double cone blender, or ribbon blender until the mixture is uniform
  • a commercially available size reduction technique such as hammer milling, impact milling, ball milling, or fluid energy milling until the desired particle size distribution is achieved.
  • compositions of the present invention are to be applied directly to the skin or hair, various applicators are useful for delivering the compositions to the occluded skin sites for maximum odor control.
  • the compositions are preferably deposited in a bottle, a canister, a spray dispenser, a manually activated spray dispenser, or on a wipe structure which later is contacted with the skin to transfer the composition to the skin.
  • Bottles and canisters known in the art are suitable for use in delivering the compositions of the present invention.
  • Bottles and canisters preferably comprise lids with small apertures for convenient dispensing of the composition.
  • composition of the present invention can also be delivered as a suspended solution via a spray dispenser or a bottle, such that when applied or sprayed onto the skin, the solvent would immediately dry/volatilize off to leave a powder film.
  • suspension forms are aerosols, liquid powder suspensions, or silicone suspensions.
  • the powders of the present invention When present in an aerosol composition, the powders of the present invention will usually be present in the range of from about 0.1% to about 15%, by weight of the composition.
  • the incorporation of a powder into an aerosol is more fully explained in U.S. Patent No. 4,078,051, to Pomot et al., issued March 7, 1978; which is incorporated herein by reference in its entirety. This method is not preferred however for use on sensitive areas of the body such as the panty-area or other occluded skin areas since skin irritations may result from propellants commonly used in aerosol containers.
  • a manually activated spray dispenser which delivers the composition as a powder without the use of propellants, and without the composition being in a solution form.
  • Spray dispensers useful in the present invention are described more fully in U.S. Patent No. 2,450,205, to Rose, issued September 28, 1948; and U.S. Patent No. 2,840,277, to Bach, issued June 24, 1958, both of which are incorporated herein by reference in their entireties.
  • the wipe comprises a flexible dispensing means.
  • flexible dispensing means includes papers, cloths, non- wovens, films, foams, sponges, rollers, pads, tissues, cotton balls, and the like.
  • Preferred wipe substrates comprise a porous material, such as the non-woven substrates, foams, or sponges, which are capable of holding the composition within the pores of the substrates. Examples of cellulosic non-wovens particularly useful and economic in the present invention is described in U.S. Patent Number 4,191,609, Trokhan, issued March 4, 1980 which is incorporated herein by reference in its entirety.
  • compositions of the present invention are well known in the art. Examples of common methods of combining the composition to the wipe substrate may involve coating, immersing, dipping, sprinkling, or spraying, the wipe substrate with the composition of the present invention.
  • the composition of the present invention is added to the wipe substrate at a level sufficient to provide the desired odor control and/or other desired skin benefits of the present invention.
  • the present invention also encompasses the use of the compositions described herein in reducing body odor and excess moisture on a human comprising the application of the compositions described herein to occluded skin.
  • the present invention also encompasses the use of the compositions described herein in reducing vaginal odor on a human comprising applying the compositions described herein onto a pelvic region, external vagina, and/or panty-area.
  • the compositions of the present invention should not be inserted into the vagina, nor applied onto the vulva.
  • an "effective amount" of the compositions of the present invention means an amount sufficient to absorb body odor and/or excess moisture to the point that body odor is not discernible by the human sense of smell and excess moisture is not present.
  • compositions of the present invention are topically applied directly to the skin or hair.
  • the compositions can be delivered by placing the composition into a dispensing means and applying an effective amount via spraying, sprinkling, shaking, or rubbing the composition onto the desired skin surface.
  • the dispensing means is a canister, a spray bottle, or a pre-formed wipe which comprises a flexible dispensing means.
  • the user may deposit the composition of the present invention onto a wipe comprising a flexible dispensing means of his or her own choosing.
  • a flexible dispensing means such as a washcloth or puff
  • the user may also use his her hand to apply the compositions of the present invention.
  • the user may use as much or as little of the composition of the present invention as he/she desires, depending upon their intended use and degree of odor and moisture control necessary.
  • the following non-limiting examples illustrate the formulations and methods of use of the present invention.
  • Examples I and II may also comprise a colorant and/or an anti-pruitic agent such as Magnesium-L-Lactate.
  • Zinc Stearate 5.00 Zinc Stearate 5.00
  • Tocopheryl Acetate Oil (Vit. E. 3.00 Mineral Oil 5.00
  • Example III may also comprise a zeolite.
  • EXAMPLE V EXAMPLE VI
  • Examples V and VI may also comprise sodium bicarbonate.
  • Example VII and VIII may also comprise an anti-pruritic agent such as Magnesium-L- Lactate.
  • an anti-pruritic agent such as Magnesium-L- Lactate.
  • Examples LX and X may also comprise a zeolite and/or a colorant.
  • EXAMPLE XI EXAMPLE XII
  • Corn Starch (Topical Starch) 10.25 Corn Starch (Topical Starch) 8.80 Oat Flour/Colloidal Oatmeal 8.35 Kaolin 4.00
  • Examples XIII and XTV may also comprise sodium bicarbonate.
  • compositions of the present invention such as those formed from the examples may be loaded onto a wipe or deposited into a spray device or canister.
  • the compositions may be applied directly onto the skin or into/onto a flexible dispensing means of the user's choosing for convenient application to the skin.
  • Example XV A woman with stress urinary incontinence finds that the wetness associated with this condition causes vaginal odor and discomfort. She wishes to reduce both the excess moisture and the vaginal odor. After urinating, the woman wipes her external vagina and pelvic region with a wipe containing the composition in Example VI. The woman notices less odor after using the wipes. Alternatively, the woman uses the composition in Example XIV and notices less odor and less moisture after using the wipes.
  • Example XVI A large-breasted woman finds that when she exercises, she tends to experience sweating and skin chafing under the breasts. Before and after exercising, she applies the composition from Example III via a manual spray bottle. She sprays the composition under her breasts and the woman notices less odor and feels more comfortable after using the powder spray. Alternatively, the woman uses the composition in Example XrV and notices less odor and less moisture after using the wipes.
  • Example XVII A man has severe allergies to cosmetic deodorants and antiperspirants and avoids using such products. This results in uncontrolled and embarrassing body odor due to excess moisture build up. His doctor suggests applying the mild odor and moisture absorbing composition of Example I or VIII. The man applies the composition to his entire body via a spray each morning after showering, and suffers no allergic reaction. The man notices less odor when using the composition of either Example I or VIII, and notices a marked reduction of moisture with the composition of Example VIII. The man keeps a pouch of wipes at work, which also contain the composition of Example VIII, for convenient and discrete reapplication as needed, particularly on hot and sweaty days.
  • Example XVHI An obese woman has several large abdominal skin folds wherein excess moisture often accumulates causing body odor. She wishes to reduce her body odor as well as the excess moisture. The woman applies the composition of Example IV by sprinkling the composition from a bottle into the palm of her hand and rubbing the composition into the intertriginous regions between her skin folds as well as other occluded skin sites. The woman notices less odor. Alternatively, the woman uses the composition in Example XI and notices less odor and less moisture after using the wipes.

Abstract

La présente invention porte sur une composition absorbant les odeurs, se présentant sous forme d'une poudre sans parfum, et qui peut être utilisée sans danger sur la peau. Cette composition comprend d'environ 0,1 % à environ 25 % en poids de cyclodextrine non complexée, et un excipient sous forme de poudre. Cette invention porte également sur une composition sous forme de poudre absorbant les odeurs et la moiteur qui comprend, de plus, d'environ 5 % à environ 60 % en poids d'un agent très efficace absorbant la moiteur. Les compositions de la présente invention peuvent également contenir des agents additionnels régulant les odeurs, sélectionnés dans le groupe constitué par des zéolites, du charbon actif, du bicarbonate de sodium, des agents antimicrobiens et des agents antisudorifiques. Cette invention porte également sur l'utilisation des compositions précitées, utilisées pour éliminer les odeurs corporelles et l'excédent de moiteur sur des sites fermés de la peau.
PCT/US1997/019262 1996-10-28 1997-10-27 Compositions permettant d'attenuer les odeurs corporelles et l'exces de moiteur WO1998018439A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CA002269471A CA2269471A1 (fr) 1996-10-28 1997-10-27 Compositions permettant d'attenuer les odeurs corporelles et l'exces de moiteur
EP97911917A EP0954276A1 (fr) 1996-10-28 1997-10-27 Compositions permettant d'attenuer les odeurs corporelles et l'exces de moiteur
IL12957197A IL129571A0 (en) 1996-10-28 1997-10-27 Compositions for reducing body odors and excess moisture
JP52061298A JP2002515890A (ja) 1996-10-28 1997-10-27 体臭および過剰湿分を減少させる組成物
IDW990256D ID23973A (id) 1996-10-28 1997-10-27 Komposisi untuk mengurangi bau badan dan kelembaban yang berlebihan
BR9712449-4A BR9712449A (pt) 1996-10-28 1997-10-27 Composições para redução dos odores e umidade em excesso dos corpos
AU49183/97A AU4918397A (en) 1996-10-28 1997-10-27 Compositions for reducing body odors and excess moisture
NO991895A NO991895L (no) 1996-10-28 1999-04-21 Blandinger for Õ nedsette kroppslukter og overskudds fuktighet

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/736,838 US5780020A (en) 1996-10-28 1996-10-28 Methods and compositions for reducing body odor
US08/736,838 1996-10-28
US08/739,091 US5885599A (en) 1996-10-28 1996-10-28 Methods and compositions for reducing body odors and excess moisture
US08/739,091 1997-10-28

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Cited By (28)

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WO1999044566A1 (fr) * 1998-03-02 1999-09-10 The Procter & Gamble Company Poudres pour le corps hautement absorbantes
WO1999055815A1 (fr) * 1998-04-27 1999-11-04 The Procter & Gamble Company Compositions de cyclodextrine non complexee ameliorees pour l'elimination des odeurs
WO1999055814A1 (fr) * 1998-04-27 1999-11-04 The Procter & Gamble Company Compositions de cyclodextrine non complexee ameliorees pour l'elimination des odeurs et des plis
WO1999055813A1 (fr) * 1998-04-27 1999-11-04 The Procter & Gamble Company Compositions de cyclodextrine non complexee ameliorees pour l'elimination des odeurs
WO2000035413A1 (fr) * 1998-12-15 2000-06-22 The Procter & Gamble Company Procede d'absorption des odeurs corporelles a l'aide de poudres contenant de la silice
US6110449A (en) * 1999-06-14 2000-08-29 The Procter & Gamble Company Anhydrous antiperspirant cream compositions improved perfume longevity
US6123932A (en) * 1999-06-14 2000-09-26 The Procter & Gamble Company Deodorant compositions containing cyclodextrin odor controlling agents
US6433243B1 (en) 1999-02-26 2002-08-13 Kimberly-Clark Worldwide, Inc. Water permeable porous layer materials treated with surfactant-modified cyclodextrins
US6479150B1 (en) 1999-02-26 2002-11-12 Kimberly-Clark Worldwide, Inc. Layer materials treated with surfactant-modified hydrophobic odor control agents
DE10123989A1 (de) * 2001-05-17 2002-11-21 Beiersdorf Ag Kosmetische und dermatologische Zubereitung zur Beseitigung und Regulation von Sebum
JP2002543243A (ja) * 1999-04-29 2002-12-17 ビーエーエスエフ アクチェンゲゼルシャフト 臭気制御性化合物を含む超吸収性ポリマー
US6509284B1 (en) 1999-02-26 2003-01-21 Kimberly-Clark Worldwide, Inc. Layer materials treated with surfacant-modified chelating agents
US6528013B1 (en) 1998-04-27 2003-03-04 The Procter & Gamble Company Uncomplexed cyclodextrin compositions for odor and wrinkle control
DE10141682A1 (de) * 2001-08-25 2003-03-06 Beiersdorf Ag Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von Füllstoffen auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und Füllstoffen
DE10141683A1 (de) * 2001-08-25 2003-03-06 Beiersdorf Ag Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von anorganischen Pigmenten auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und anorganischen Pigmenten
JP2003095906A (ja) * 2001-09-27 2003-04-03 Lion Corp 制汗デオドラント組成物
US6623848B2 (en) 1999-08-20 2003-09-23 Stockhausen Gmbh & Co. Kg Water-absorbing polymers having interstitial compounds, a process for their production, and their use
US6649155B1 (en) 1999-05-03 2003-11-18 The Procter & Gamble Company Anti-dandruff and conditioning shampoos containing certain cationic polymers
US7029704B2 (en) 2003-12-29 2006-04-18 Woods Jr Clifford E Anti-itch solution
US8147808B2 (en) 2005-05-19 2012-04-03 The Procter & Gamble Company Consumer noticeable improvement in wetness protection using solid antiperspirant compositions
US8318806B2 (en) 2007-10-03 2012-11-27 Zorbx Inc. Deodorizing composition and method of forming thereof
US8632755B2 (en) 2005-05-19 2014-01-21 The Procter & Gamble Company Consumer noticeable improvement in wetness protection
US8895041B2 (en) 2012-03-23 2014-11-25 The Procter & Gamble Company Compositions for delivering perfume to the skin
US9649386B2 (en) 2007-03-01 2017-05-16 The Procter & Gamble Company Compositions and/or articles comprising cyclodextrin complexing material
WO2017100875A1 (fr) * 2015-12-17 2017-06-22 L'oreal Composition antitranspirante anhydre sous forme de poudre
US10323131B2 (en) 2007-02-20 2019-06-18 Cellresin Technologies, Llc Combination of substituted cyclodextrin compound and activated carbon
WO2020076501A1 (fr) * 2018-10-10 2020-04-16 Hollister Incorporated Poudre pour stomie comprenant des ingrédients de santé de la peau
US11090250B2 (en) 2007-03-01 2021-08-17 The Procter & Gamble Company Compositions and/or articles comprising cyclodextrin complexing material

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KR101502076B1 (ko) * 2014-07-11 2015-03-12 백영배 체취 억제용 화장 조성물
CN107669586B (zh) * 2017-10-19 2021-04-27 北京天然风尚健康科技有限公司 一种纯天然腋下除味膏及其制备方法和用途

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JPH03170415A (ja) * 1989-11-30 1991-07-24 Sunstar Inc 制汗用エアゾール組成物
WO1994022500A1 (fr) * 1993-03-31 1994-10-13 The Procter & Gamble Company Articles absorbants pour combattre les odeurs, emettant un signal odorant agreable attestant de leur bon fonctionnement
WO1994022501A1 (fr) * 1993-03-31 1994-10-13 The Procter & Gamble Company Articles contenant de petites particules de cyclodextrine pour combattre les odeurs
US5429628A (en) * 1993-03-31 1995-07-04 The Procter & Gamble Company Articles containing small particle size cyclodextrin for odor control

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Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999044566A1 (fr) * 1998-03-02 1999-09-10 The Procter & Gamble Company Poudres pour le corps hautement absorbantes
US6528013B1 (en) 1998-04-27 2003-03-04 The Procter & Gamble Company Uncomplexed cyclodextrin compositions for odor and wrinkle control
WO1999055815A1 (fr) * 1998-04-27 1999-11-04 The Procter & Gamble Company Compositions de cyclodextrine non complexee ameliorees pour l'elimination des odeurs
WO1999055814A1 (fr) * 1998-04-27 1999-11-04 The Procter & Gamble Company Compositions de cyclodextrine non complexee ameliorees pour l'elimination des odeurs et des plis
WO1999055813A1 (fr) * 1998-04-27 1999-11-04 The Procter & Gamble Company Compositions de cyclodextrine non complexee ameliorees pour l'elimination des odeurs
WO2000035413A1 (fr) * 1998-12-15 2000-06-22 The Procter & Gamble Company Procede d'absorption des odeurs corporelles a l'aide de poudres contenant de la silice
US6433243B1 (en) 1999-02-26 2002-08-13 Kimberly-Clark Worldwide, Inc. Water permeable porous layer materials treated with surfactant-modified cyclodextrins
US6479150B1 (en) 1999-02-26 2002-11-12 Kimberly-Clark Worldwide, Inc. Layer materials treated with surfactant-modified hydrophobic odor control agents
US6509284B1 (en) 1999-02-26 2003-01-21 Kimberly-Clark Worldwide, Inc. Layer materials treated with surfacant-modified chelating agents
JP4933696B2 (ja) * 1999-04-29 2012-05-16 ビーエーエスエフ ソシエタス・ヨーロピア 臭気制御性化合物を含む超吸収性ポリマー
JP2002543243A (ja) * 1999-04-29 2002-12-17 ビーエーエスエフ アクチェンゲゼルシャフト 臭気制御性化合物を含む超吸収性ポリマー
US6649155B1 (en) 1999-05-03 2003-11-18 The Procter & Gamble Company Anti-dandruff and conditioning shampoos containing certain cationic polymers
WO2000076472A1 (fr) * 1999-06-14 2000-12-21 The Procter & Gamble Company Compositions de creme desodorisante anhydre ayant une duree de vie plus longue du parfum
US6123932A (en) * 1999-06-14 2000-09-26 The Procter & Gamble Company Deodorant compositions containing cyclodextrin odor controlling agents
US6110449A (en) * 1999-06-14 2000-08-29 The Procter & Gamble Company Anhydrous antiperspirant cream compositions improved perfume longevity
US6623848B2 (en) 1999-08-20 2003-09-23 Stockhausen Gmbh & Co. Kg Water-absorbing polymers having interstitial compounds, a process for their production, and their use
DE10123989A1 (de) * 2001-05-17 2002-11-21 Beiersdorf Ag Kosmetische und dermatologische Zubereitung zur Beseitigung und Regulation von Sebum
DE10141682A1 (de) * 2001-08-25 2003-03-06 Beiersdorf Ag Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von Füllstoffen auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und Füllstoffen
DE10141683A1 (de) * 2001-08-25 2003-03-06 Beiersdorf Ag Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von anorganischen Pigmenten auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und anorganischen Pigmenten
JP2003095906A (ja) * 2001-09-27 2003-04-03 Lion Corp 制汗デオドラント組成物
US7029704B2 (en) 2003-12-29 2006-04-18 Woods Jr Clifford E Anti-itch solution
US8632755B2 (en) 2005-05-19 2014-01-21 The Procter & Gamble Company Consumer noticeable improvement in wetness protection
US8147808B2 (en) 2005-05-19 2012-04-03 The Procter & Gamble Company Consumer noticeable improvement in wetness protection using solid antiperspirant compositions
US10323131B2 (en) 2007-02-20 2019-06-18 Cellresin Technologies, Llc Combination of substituted cyclodextrin compound and activated carbon
US10149910B2 (en) 2007-03-01 2018-12-11 The Procter & Gamble Plaza Compositions and/or articles comprising cyclodextrin complexing material
US11090250B2 (en) 2007-03-01 2021-08-17 The Procter & Gamble Company Compositions and/or articles comprising cyclodextrin complexing material
US9649386B2 (en) 2007-03-01 2017-05-16 The Procter & Gamble Company Compositions and/or articles comprising cyclodextrin complexing material
US9649387B2 (en) 2007-03-01 2017-05-16 The Procter & Gamble Company Compositions and/or articles comprising cyclodextrin complexing material
US8318806B2 (en) 2007-10-03 2012-11-27 Zorbx Inc. Deodorizing composition and method of forming thereof
US9364417B2 (en) 2012-03-23 2016-06-14 The Procter & Gamble Company Compositions for delivering perfume to the skin
US9161899B2 (en) 2012-03-23 2015-10-20 The Procter & Gamble Company Compositions for delivering perfume to the skin
US8895041B2 (en) 2012-03-23 2014-11-25 The Procter & Gamble Company Compositions for delivering perfume to the skin
WO2017100875A1 (fr) * 2015-12-17 2017-06-22 L'oreal Composition antitranspirante anhydre sous forme de poudre
WO2020076501A1 (fr) * 2018-10-10 2020-04-16 Hollister Incorporated Poudre pour stomie comprenant des ingrédients de santé de la peau
CN113038935A (zh) * 2018-10-10 2021-06-25 霍利斯特公司 含有皮肤愈合成分的造口粉

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CZ147499A3 (cs) 1999-09-15
NO991895L (no) 1999-06-28
NO991895D0 (no) 1999-04-21
AU4918397A (en) 1998-05-22
IL129571A0 (en) 2000-02-29
CN1307467A (zh) 2001-08-08

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