WO1997000076A1 - Compositions contenant des sels de poly(hexamethylene biguanide) et leurs utilisations - Google Patents

Compositions contenant des sels de poly(hexamethylene biguanide) et leurs utilisations Download PDF

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Publication number
WO1997000076A1
WO1997000076A1 PCT/GB1996/001457 GB9601457W WO9700076A1 WO 1997000076 A1 WO1997000076 A1 WO 1997000076A1 GB 9601457 W GB9601457 W GB 9601457W WO 9700076 A1 WO9700076 A1 WO 9700076A1
Authority
WO
WIPO (PCT)
Prior art keywords
salt
eye
poly
hexamethylene biguanide
use
Prior art date
Application number
PCT/GB1996/001457
Other languages
English (en)
Inventor
Nigel Morlet
Frank Larkin
John Dart
Victor Andrews
Original Assignee
Moorfields Eye Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB9512290.9 priority Critical
Priority to GBGB9512290.9A priority patent/GB9512290D0/en
Application filed by Moorfields Eye Hospital filed Critical Moorfields Eye Hospital
Publication of WO1997000076A1 publication Critical patent/WO1997000076A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen

Abstract

Utilisations de sels de poly(héxaméthylène biguanide), en particulier le sel d'hydrochlorure, dans la fabrication de médicaments pour le traitement local des infections microbiennes, et méthodes de traitement afférentes. L'invention a également trait à des préparations pharmaceutiques, des antiseptiques, des désinfectants et des formulations liquides renfermant un sel de poly(hexaméthylène biguanide).
PCT/GB1996/001457 1995-06-16 1996-06-17 Compositions contenant des sels de poly(hexamethylene biguanide) et leurs utilisations WO1997000076A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GB9512290.9 1995-06-16
GBGB9512290.9A GB9512290D0 (en) 1995-06-16 1995-06-16 Uses of polyhexanide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AU61308/96A AU6130896A (en) 1995-06-16 1996-06-17 Compositions containing poly(hexamethylene biguanide) salts and uses thereof

Publications (1)

Publication Number Publication Date
WO1997000076A1 true WO1997000076A1 (fr) 1997-01-03

Family

ID=10776200

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1996/001457 WO1997000076A1 (fr) 1995-06-16 1996-06-17 Compositions contenant des sels de poly(hexamethylene biguanide) et leurs utilisations

Country Status (3)

Country Link
AU (1) AU6130896A (fr)
GB (1) GB9512290D0 (fr)
WO (1) WO1997000076A1 (fr)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0788797A1 (fr) * 1996-02-08 1997-08-13 Fresenius AG L'usage de PHMB pour le traitement des infections causées par germes qui se propagent intracellulairement
GB2323279A (en) * 1997-03-20 1998-09-23 Medeva Europ Ltd Polybiguanide Preservative
WO2000018442A1 (fr) * 1998-09-25 2000-04-06 Becton, Dickinson And Company Solution de rinçage de catheter et procede d'utilisation associe
WO2001062237A2 (fr) * 2000-02-23 2001-08-30 Orentreich Foundation For The Advancement Of Science, Inc. Methodes et compositions de traitement de l'alopecie et d'autres troubles de l'appareil pilosebace
WO2003037356A1 (fr) * 2001-10-26 2003-05-08 Fresenius Kabi Deutschland Gmbh Composition pharmaceutique contenant un facteur de croissance et/ou une cytokine et un biguanide antiseptique
WO2004093545A1 (fr) * 2003-04-11 2004-11-04 Bausch & Lomb Incorporated Solutions desinfectantes efficaces contre les endospores bacteriennes
WO2006066752A1 (fr) * 2004-12-21 2006-06-29 Bayer Innovation Gmbh Mousses polyurethane resistantes a l'infection, leur procede de production et leur utilisation dans des pansements a action antiseptique
EP2165701A1 (fr) * 2008-09-18 2010-03-24 Croma-Pharma Gesellschaft m.b.H. Composition active antimicrobienne et antivirale
WO2010031096A1 (fr) * 2008-09-18 2010-03-25 Croma-Pharma Gesellschaft M.B.H. Composition à action antimicrobienne et antivirale
AU2005282377B2 (en) * 2004-09-07 2011-07-28 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
US8198326B2 (en) 2004-09-07 2012-06-12 3M Innovative Properties Company Phenolic antiseptic compositions and methods of use
US8338491B2 (en) 2006-10-27 2012-12-25 3M Innovative Properties Company Antimicrobial compositions
DE102012007212A1 (de) * 2012-04-11 2013-10-17 Merz Pharma Gmbh & Co. Kgaa Zubereitung zur topischen Anwendung auf Schleimhäuten mit Polyhexanid als Wirkstoff
US8623935B2 (en) 2007-12-31 2014-01-07 3M Innovative Properties Company Antimicrobial compositions
CN104398534A (zh) * 2014-11-04 2015-03-11 卫国刚 聚六亚甲基胍滴眼液
US9826770B2 (en) 2005-03-10 2017-11-28 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxycarboxylic acids
US9848604B2 (en) * 2014-07-11 2017-12-26 Medtronic Xomed, Inc. Antimicrobial wash

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405645A (en) * 1980-04-02 1983-09-20 Wella Aktiengesellschaft Treatment of dandruff with biguanides
JPS63183502A (en) * 1986-09-04 1988-07-28 Ueno Seiyaku Oyo Kenkyusho:Kk Virus inactivating agent
EP0293761A2 (fr) * 1987-05-26 1988-12-07 Allpro Venture Oy Agent désinfectant et son utilisation pour la désinfection de la peau et des surfaces d'objets
EP0450117A1 (fr) * 1990-04-02 1991-10-09 Infectless S.A. Solution de Ringer et son utilisation en tant que médicament à effet bactéricide pour traitement local des blessures
EP0468122A1 (fr) * 1989-03-10 1992-01-29 Guy Andermann Composition thérapeutique à base de polihexanide pour le traitement des manifestations cutanées, oculaires et génitales de l'herpès
WO1994027440A1 (fr) * 1993-05-26 1994-12-08 Fresenius Ag Agents anti-infectieux

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405645A (en) * 1980-04-02 1983-09-20 Wella Aktiengesellschaft Treatment of dandruff with biguanides
JPS63183502A (en) * 1986-09-04 1988-07-28 Ueno Seiyaku Oyo Kenkyusho:Kk Virus inactivating agent
EP0293761A2 (fr) * 1987-05-26 1988-12-07 Allpro Venture Oy Agent désinfectant et son utilisation pour la désinfection de la peau et des surfaces d'objets
EP0468122A1 (fr) * 1989-03-10 1992-01-29 Guy Andermann Composition thérapeutique à base de polihexanide pour le traitement des manifestations cutanées, oculaires et génitales de l'herpès
EP0450117A1 (fr) * 1990-04-02 1991-10-09 Infectless S.A. Solution de Ringer et son utilisation en tant que médicament à effet bactéricide pour traitement local des blessures
WO1994027440A1 (fr) * 1993-05-26 1994-12-08 Fresenius Ag Agents anti-infectieux

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 8836, Derwent World Patents Index; Class B04, AN 88-253361, XP002015831 *
ELDER ET AL: "A clinicopathologic study of in vitro sensitivity testing and Acanthamoeba keratitis", OPHTALM. & VIS. SCI., vol. 35, 1994, pages 1059 - 64, XP000603790 *
H.W. TIKUS: "Topical gels containing chlorhexidine,vantocil, fluorophene and animal caries", HELV. ODONT. ACTA, vol. 17, no. 2, 1973, pages 105 - 8, XP000603388 *

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0788797A1 (fr) * 1996-02-08 1997-08-13 Fresenius AG L'usage de PHMB pour le traitement des infections causées par germes qui se propagent intracellulairement
US6403363B1 (en) 1997-03-20 2002-06-11 Medeva Europe Limited Method of preservation of vaccines with polybiguanide
WO1998042373A1 (fr) * 1997-03-20 1998-10-01 Medeva Europe Limited Methode de preservation de vaccins mettant en oeuvre un polybiguanide
GB2323279B (en) * 1997-03-20 2001-02-07 Medeva Europ Ltd A method of preservation
GB2323279A (en) * 1997-03-20 1998-09-23 Medeva Europ Ltd Polybiguanide Preservative
WO2000018442A1 (fr) * 1998-09-25 2000-04-06 Becton, Dickinson And Company Solution de rinçage de catheter et procede d'utilisation associe
WO2001062237A2 (fr) * 2000-02-23 2001-08-30 Orentreich Foundation For The Advancement Of Science, Inc. Methodes et compositions de traitement de l'alopecie et d'autres troubles de l'appareil pilosebace
AU2001239826B2 (en) * 2000-02-23 2006-06-15 Orentreich Foundation For The Advancement Of Science, Inc. Methods and compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus
US7105573B2 (en) 2000-02-23 2006-09-12 Orentreich Foundation For The Advancement Of Science, Inc. Methods and compositions for the treatment of alopecia and other disorders of the pilosebaceous apparatus
WO2001062237A3 (fr) * 2000-02-23 2002-06-13 Rozlyn A Krajcik Methodes et compositions de traitement de l'alopecie et d'autres troubles de l'appareil pilosebace
WO2003037356A1 (fr) * 2001-10-26 2003-05-08 Fresenius Kabi Deutschland Gmbh Composition pharmaceutique contenant un facteur de croissance et/ou une cytokine et un biguanide antiseptique
WO2004093545A1 (fr) * 2003-04-11 2004-11-04 Bausch & Lomb Incorporated Solutions desinfectantes efficaces contre les endospores bacteriennes
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
US8198326B2 (en) 2004-09-07 2012-06-12 3M Innovative Properties Company Phenolic antiseptic compositions and methods of use
AU2005282377B2 (en) * 2004-09-07 2011-07-28 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
US10016501B2 (en) 2004-09-07 2018-07-10 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
WO2006066752A1 (fr) * 2004-12-21 2006-06-29 Bayer Innovation Gmbh Mousses polyurethane resistantes a l'infection, leur procede de production et leur utilisation dans des pansements a action antiseptique
US8147857B2 (en) 2004-12-21 2012-04-03 Bayer Innovation Gmbh Infection-resistant polyurethane foams, method for producing the same and use thereof in antiseptic wound dressings
EA016503B1 (ru) * 2004-12-21 2012-05-30 Байер Инновейшн Гмбх Ячеистый гидрофильный полиуретановый гель, способ его получения и применение этого ячеистого гидрофильного полиуретанового геля для изготовления изделия медицинского назначения и повязка на рану, содержащая этот ячеистый гидрофильный полиуретановый гель
AU2005318512B2 (en) * 2004-12-21 2009-09-24 Bayer Innovation Gmbh Infection-resistant polyurethane foams, method for producing the same and use thereof in antiseptic wound dressings
US9826770B2 (en) 2005-03-10 2017-11-28 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxycarboxylic acids
US8338491B2 (en) 2006-10-27 2012-12-25 3M Innovative Properties Company Antimicrobial compositions
US8569384B2 (en) 2006-10-27 2013-10-29 3M Innovative Properties Company Antimicrobial compositions
US8623935B2 (en) 2007-12-31 2014-01-07 3M Innovative Properties Company Antimicrobial compositions
EP2165701A1 (fr) * 2008-09-18 2010-03-24 Croma-Pharma Gesellschaft m.b.H. Composition active antimicrobienne et antivirale
WO2010031096A1 (fr) * 2008-09-18 2010-03-25 Croma-Pharma Gesellschaft M.B.H. Composition à action antimicrobienne et antivirale
WO2013152838A1 (fr) 2012-04-11 2013-10-17 Merz Pharma Gmbh & Co. Kgaa Préparation pour application locale sur les muqueuses, contenant un polyhexanide comme substance active
DE102012007212A1 (de) * 2012-04-11 2013-10-17 Merz Pharma Gmbh & Co. Kgaa Zubereitung zur topischen Anwendung auf Schleimhäuten mit Polyhexanid als Wirkstoff
US9848604B2 (en) * 2014-07-11 2017-12-26 Medtronic Xomed, Inc. Antimicrobial wash
CN104398534A (zh) * 2014-11-04 2015-03-11 卫国刚 聚六亚甲基胍滴眼液

Also Published As

Publication number Publication date
AU6130896A (en) 1997-01-15
GB9512290D0 (en) 1995-08-16

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