WO1996008425A2 - Dispositif de traitement de l'air et procede d'utilisation de ce dispositif - Google Patents

Dispositif de traitement de l'air et procede d'utilisation de ce dispositif Download PDF

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Publication number
WO1996008425A2
WO1996008425A2 PCT/US1995/011557 US9511557W WO9608425A2 WO 1996008425 A2 WO1996008425 A2 WO 1996008425A2 US 9511557 W US9511557 W US 9511557W WO 9608425 A2 WO9608425 A2 WO 9608425A2
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WO
WIPO (PCT)
Prior art keywords
solvent
perfume
air treatment
air
propellant
Prior art date
Application number
PCT/US1995/011557
Other languages
English (en)
Other versions
WO1996008425A3 (fr
Inventor
Christopher J. Miller
Carl Triplett
Mark W. Mcelfresh
Yeong C. Park
Guy Anthony Williams
Thomas B. Aldrich, Iii
Original Assignee
The Dial Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Dial Corp filed Critical The Dial Corp
Priority to AU35517/95A priority Critical patent/AU3551795A/en
Publication of WO1996008425A2 publication Critical patent/WO1996008425A2/fr
Publication of WO1996008425A3 publication Critical patent/WO1996008425A3/fr

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/38Details of the container body
    • B65D83/384Details of the container body comprising an aerosol container disposed in an outer shell or in an external container
    • B65D83/386Details of the container body comprising an aerosol container disposed in an outer shell or in an external container actuation occurring by moving the aerosol container relative to the outer shell or external container
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/01Deodorant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/14Disinfection, sterilisation or deodorisation of air using sprayed or atomised substances including air-liquid contact processes

Definitions

  • This invention relates generally to dispensers for use with air-treating formulations, preferably air freshening formulations. More particularly, this invention relates to a novel air treatment formulation and a method and apparatus for dispensing the same.
  • odors tend to gather in areas such as those existing in homes, offices and the like. As is also well known, on occasion these odors can be unpleasant, and the unpleasant odors can gather in an area in these structures. This tendency of malodors to gather is exacerbated in homes and other buildings that are constructed in an energy-efficient manner. Typically, homes and other buildings are constructed in a manner that essentially prevents air circulation between the inside and outside of the building. In these buildings malodors can accumulate to offensive levels.
  • the present invention relates generally to the treatment of air for a wide variety of purposes, including removing malodors, removing or killing germs and the like
  • this invention and the problems it addresses will be described primarily with reference to air treatment in the form of air freshening, namely the adding of fragrances to the air such that the odors which tend to accumulate in such buildings and/or homes can be effectively treated.
  • air treatment in the form of air freshening, namely the adding of fragrances to the air such that the odors which tend to accumulate in such buildings and/or homes can be effectively treated.
  • a wide variety of devices and methods are known for the dispensing of fragrances to the air.
  • known devices can be characterized as being configured for instant treatment of the air, continuous treatment of the air, or a combination of both.
  • Exemplary of instant treatment devices are the well- known aerosol spray cans which contain aerosols comprising a fragrance, which aerosols can be sprayed throughout a particular room or building.
  • Exemplary of continuous air- treating devices are those devices which generally comprise a fragrance impregnated and/or releasing element which is suitably placed in an area were freshening is desired.
  • the present invention has particular usefulness in connection with instant treatment type devices.
  • these types of devices for dispensing fluid from aerosol containers generally include a spray stem or spray head which, when actuated, disperses fluid from the container.
  • the fluid preferably comprises a fragrance (e.g. perfume).
  • a widely-employed procedure for packaging such fluids e.g.
  • fragrance-containing fluids and facilitating their dispersion into the air is through the use of aerosol products (e.g. hydrocarbon products).
  • aerosol products e.g. hydrocarbon products.
  • the fragrance (perfume) is dissolved or dispersed in a fluid composition, normally an aqueous solution, and carried by a propellant, such as a hydrocarbon, in a container having a valved spray nozzle.
  • a propellant such as a hydrocarbon
  • Air fresheners which may be activated by certain events and thereby disperse a metered amount of an aerosol air freshener into a building are known.
  • U.S. Patent No. 4,570,824, issued February 18, 1986 to Boiling discloses a doorbell-actuated air freshener. In operation, an actuation mechanism of an air freshener is connected to a doorbell system for a house.
  • the actuation device When the doorbell rings, the actuation device causes a metered amount of the aerosol air freshener to be released into a convenient location in the room. While generally addressing the difficulties associated with waste, such a device is of limited use for general household purposes or normal use within homes.
  • actuators for dispensing aerosols from various types of bottles are known. See, for example, U.S. Patent No. 3,157,317 issued November 17, 1964 to Ramsbotham for a holder for bottles and the like, U.S. Patent No. 3,272,391 issued September 13, 1966 to Meshberg for an actuator for dispensing various materials under pressure and U.S. Patent No. 3,549,055 issued December 22, 1970 to Gatland for an aerosol clam-shell dispenser. It is noted that the '055 and '391 patents each relate to devices in which pressure upon a housing causes actuation of the aerosol container and release of the contents of the container.
  • the present invention addresses this long-felt need by providing an air freshener which comprises a pressurized vessel containing a concentrated air-treating composition.
  • the vessel includes a metered valve and a depressible valve stem.
  • the air freshener further comprises a dispenser for supporting the vessel.
  • the dispenser comprises a first housing section which has a dispensing aperture suitably positioned for communication with the valve stem of the vessel, and a second housing section having a removable securing device for the vessel.
  • the first housing is movable with respect to the second housing.
  • the vessel suitably contains a highly fragrant air-treating composition.
  • the composition consists essentially of about 20 to about 50 wt. % of a propellant, about 5 to about 10 wt. % alcohol, and about 40 to about 55 wt. % of a perfume. More particularly, a first composition preferably consists essentially of about 5 wt. % ethanol, about 50 wt. % perfume and about 45 wt. % of a propellant.
  • the composition comprises from about 10 to about 60 wt. % of a perfume, about 27 to about 90 wt.
  • the second composition preferably consists essentially of about 5 wt. % ethanol, about 30 wt. % isopropyl myristate, about 20 wt. % perfume and about 45 wt. % of a propellant.
  • a method of treating air includes the steps of providing a dispenser for use with an aerosol container which has a device for removably receiving an aerosol container and a device for actuating the aerosol container, and providing an aerosol container of a concentrated air treatment composition.
  • the method further includes the steps of inserting the aerosol container in the dispenser through actuation of said removable container receiving device, and actuating the aerosol container to release the air treatment composition.
  • FIG. 1 is a perspective view of an aerosol dispenser in accordance with the present invention.
  • Figure 2 is a side view of the upper portion of the dispenser according to Figure 1 ;
  • Figure 3 is a top view of the lower portion of the dispenser according to Figure 1 ;
  • Figure 4 is a sectional view along the line 4-4 of Figure 1.
  • Figure 5 is a sectional view along the lines 5-5 of Figure 1 , showing the aerosol container in phantom;
  • Figure 6 is a sectional view similar to that of Figure 4 showing operation of the dispenser according to Figure 1;
  • Figure 7 is a bottom view of the dispenser according to Figure 1;
  • Figure 8 is a perspective of the bottom view of an alternative embodiment of the device of Figure 1;
  • Figure 9 is a plot of fragrance intensity on a composition matrix for aerosol mixtures of perfume, ethanol and dipropylene glycol.
  • Apparatus 10 preferably includes an upper portion 12 and a lower portion 14.
  • Upper portion 12 preferably includes a dispensing aperture 16 suitably surrounded by a collection reservoir 18.
  • the diameter of dispensing aperture 16 is optimally in the range of between about 13 and about 25 millimeters (mm), more preferably about 15 to about 20 mm, and optimally about 20 mm.
  • apparatus 10 preferably contains a container (vessel) 20 which may be of a conventional configuration.
  • container 20 preferably comprises an aerosol container and suitably includes a valve 22 suitably securely affixed to a canister 23.
  • a valve actuating stem 24 is suitably disposed in valve 22 and preferably includes a delivery aperture 26 configured to communicate with the interior of container 20, such that upon actuation of stem 24 (e.g. stem 24 being depressed in the downward direction), a predetermined amount of aerosol formulation is released from container 20.
  • aerosol container 20 is secured within lower portion 14 by a retainer 30 formed interiorly of portions 12 and 14.
  • retainer 30 comprises a support collar 40 which terminates in respective legs 42 and 44 formed internally of lower portion 14.
  • a protuberance 38 extending inwardly from wall 36 configured to form upper portion 12 aids in retention of container 20 within device 10.
  • protuberance 38 is suitably configured to receive actuating stem 24 of container 20, thereby providing communication between delivery aperture 26 and dispensing aperture 16.
  • dispensing aperture 16 is preferably formed in the center of protuberance 38 such that protuberance 38 suitably surrounds aperture 16.
  • protuberance 38 is configured to have a height sufficient to retain the upper portion of stem 24; to that end, the height of protuberance 38 is in the range of about 0J to about 0.3 inches (in.), and more preferably about 0.25 in.
  • the lower portion of retainer 30 includes legs 42 and 44, each of which terminates at its distal end in respective actuating tabs 46 and 48.
  • actuating tabs 46 and 48 permit a user of apparatus 10 to easily "load” and “unload” container 20 directly to and from apparatus 10.
  • container 20 may be of any convenient form.
  • container 20 may comprise metal, glass, or plastic.
  • container 20 employed in apparatus 10 comprises a conventional aerosol container, such as is now known or hereafter devised by those skilled in the art.
  • a conventional aerosol container such as is now known or hereafter devised by those skilled in the art.
  • canisters made from impact- extruded aluminum may be suitably employed.
  • diat apparatus 10 may also be used in conjunction with non-aerosol, i.e. "pump-type", containers.
  • container 20 would be suitably modified to enable the air- treatment compound contained therein to be effectively evacuated.
  • valve 22 instead of valve 22, a pump or other device likely would be used.
  • container 20 comprises a standard aluminum aerosol container having a capacity in the range of about 15 to about 30 milliliters (ml), preferably in the range of about 20 ml.
  • Container 20 preferably exhibits conventional cylindrical dimensions; thus, container 20 suitably exhibits a diameter in the range of about 15 to about 30 mm and a height H in the range of about 50 mm to about 80 mm.
  • container 20 comprises an aluminum aerosol container having a diameter of about 22 mm and a height H of about 58 mm. It should be appreciated that while the present invention will be discussed in the context of use of aerosol container 20 as just described, any container of suitable size and dimension may be utilized in apparatus 10, and apparatus 10 may be suitably configured to house such a container.
  • Valve 22 may also be of any convenient form such as is now known or hereafter devised by those of ordinary skill in the art.
  • valve 22 comprises a metering valve suitably configured to release between about 75 and about 150 microliters ( ⁇ l ) of the formulation contained within container 20, more preferably from about 95 to about 120 ⁇ l, and optimally about 120 ⁇ l of formulation when actuated.
  • ⁇ l microliters
  • Upper portion 12 and lower portion 14 of apparatus 10 are suitably formed from, for example, a plastic material, preferably a thermoplastic material.
  • upper portion 12 and lower portion 14 comprise polypropylene and are formed by conventional injection molding techniques. It should be appreciated that portions 12 and 14 are preferably suitably constructed to provide a relatively simple, yet sturdy, dispensing apparatus 10.
  • upper portion 12 suitably comprises a substantially crescent-shaped housing formed from wall 36.
  • wall 36 is formed in a generally arcuate, U-shaped configuration with respective reinforcing walls 32 and 34 spanning therebetween.
  • wall 36 is substantially rigid and is further reinforced by walls 32 and 34.
  • walls 32 and 34 if employed, are suitably positioned within surface 36 so that the lowermost ends thereof engage the uppermost part of collar 40 when upper portion 12 and lower portion 14 are assembled together.
  • walls 32 and 34 having a sufficient depth, are positioned so that when apparatus 10 is assembled, walls 32 and 34 each mates against an outer surface of collar 40 of retainer 30. Such a construction further ensures proper alignment and rigidity of the components of apparatus 10.
  • wall 36 of portion 12 is also formed in a generally elliptical configuration with the major axis being larger than the minor axis.
  • wall 36 of upper portion 12 preferably has a thickness in the range of 0.75 to about 2.0 mm, more preferably about 1.2 mm.
  • Respective engaging members 50 and 52 are suitably carried on each opposing end of upper portion 12 at distal ends of the major axis thereof.
  • engaging members 50 and 52 each preferably comprise resiliently deflectable legs 54 and 56, which terminate in respective locking nibs 58 and 60.
  • locking nibs 58 and 60 are formed as angularly disposed ledges carried on the outside portion of legs 54 and 56.
  • legs 54 and 56 have a length of from about 3 to about 15 mm, and optimally have a length of about 6.4 mm (0.25 in.).
  • lower portion 14 is also preferably formed in a generally elliptical configuration and has a substantially rigid construction.
  • lower portion 14 comprises an outer surface 64 having a thickness in the range of 0.75 to 2.5 mm, preferably about 2.0 mm.
  • Surface 64 generally exhibits an elliptical cross- section ( Figure 3), including a major axis "f ' and a minor axis "w".
  • major axis T has a length in the range of between about 8 and 12 centimeters (cm), preferably about 10 cm; minor axis "w” suitably has a length of between about 2.5 and about 5 cm, and preferably about 3.8 cm.
  • upper portion 12 and lower portion 14 are similarly dimensioned. Further, and in accordance with a preferred aspect of the present invention, the ratio of length to width of portions 12 and 14 is in the range of about 2: 1 to about 3: 1, more preferably about 2.67:1. Such a construction provides for enhanced stability of apparatus 10 when in use, as discussed in greater detail hereinbelow.
  • a support surface 66 substantially spans the ellipse defined by surface 64 of portion 14.
  • retainer 30 suitably extends from surface 66.
  • Respective attaching slots 70 and 72 are preferably disposed at the distal ends of major axis "l" of the ellipse formed by outer surface 64. Attaching slots 70 and 72 are suitably configured to receive attaching members 50 and 52 of upper portion 12.
  • attaching slots 70 and 72 are preferably formed in such a manner as to provide respective locking ribs 74 and 76.
  • ribs 74 and 76 are suitably configured to engage locking nibs 58 and 60 of attaching members 50 and 52.
  • Collar 40 is preferably carried by platform 66, with respective apertures 80 and 82 formed in proximity to legs 42 and 44 within platform 66.
  • legs 42 and 44 preferably extend from support collar 40.
  • legs 42 and 44 are suitably configured such that they are movable within a plane defined along the major axis of lower portion 14 (i.e. along arrows 92 and 94 in Figure 4). While certainly not described in a limiting sense, in that any orientation of legs 42 and 44 is usable in the context of the present invention, it should be recognized that the orientation of legs 42 and 44 in this fashion provides for greater ease of movement and manipulation of such legs in operation and use of apparatus 10, as will be discussed in greater detail hereinbelow.
  • respective relief slits 84 and 86 are provided within support wall 40 adjacent leg 44.
  • upper portion 12 and lower portion 14 are suitably formed such that upper portion 12 fits within lower portion 14 and is removably retained therein.
  • upper portion 12 is suitably dimensioned such that it fits within the area defined by surface 66 and outer surface 64 of lower portion 14.
  • Attaching members 50 and 52 preferably are carried within attaching slot 70 and 72 such that locking nibs 58 and 60 engage locking ribs 74 and 76 when upper portion 12 and lower portion 14 are in their normal engaged positions.
  • upper portion 12 is upwardly and downwardly movable with respect to lower portion 14.
  • upper portion 12 is caused to move downwardly relative to lower portion 14 such that stem 24 actuates valve 22 and the aerosol contained within canister 23 is released.
  • Further movement of upper portion 12 relative to lower portion 14, however, is preferably restrained by the configuration of such portions, for example by the length of leg members 54 and 56 or as a result of the lower portion of wall 36 contacting support platform 66.
  • stem 24 is returned to its normal position as valve 22 closes.
  • stem 24 is moved upward, given the relationship between stem 24 and protuberance 38, upper portion 12 is returned to its normal position.
  • the relative movement of upper portion 12 with respect to lower portion 14 can be suitably controlled by varying the lengths of members 50 and 52, or the orientation of surface 66, and/or other variation as may be desired.
  • Apparatus 10 is suitably of a convenient size for placement in a room, such as a room in a house, building or other structure.
  • apparatus 10 has an overall length on the order of about 10 to about 15 cm and an overall height on the order of about 5 and to about 10 cm.
  • upper portion 12 and/or lower portion 14 are provided with decorative and ornamental attributes to increase the aesthetic appearance of apparatus 10.
  • at least lower portion 14 is provided with a series of decorative ribs 90 carried on the outer portion of wall 64. Ribs 90 can be configured, as shown in the illustrated embodiment, to generally replicate the overall shape of upper portion 12 (see Figure 2).
  • apparatus 10 When utilized in a room, and as briefly discussed hereinabove, apparatus 10 is used to actuate valve 22 of container 20 such that a metered amount of the air-treating formulation is dispersed into the air in the room. In so dispensing the formulation, it is desirable to ensure that the formulation expands rapidly, and is readily and widely dispersed into the air.
  • the present inventors have undertaken an analysis of various fragrance formulations to identify particular formulations having optimal efficacy when used in apparatus 10.
  • Formulations having conventional perfume solvents e.g. dipropylene glycol (DPG) and the like, were investigated.
  • fragrance formulations comprised of all or a major portion of a perfume would have the highest fragrance intensity, resulting in a sustained presence of the fragrance within a room.
  • formulations yielding optimal fragrance intensities do not comprise solely perfume, but instead a mixture of perfume and alcohol, or perfume and solvent, or more particularly perfume and an alcohol or solvent/co-solvent mixture.
  • the formulation comprises, in general, a perfume and up to about 80 wt. % ethanol, more preferably in the range of about 5 to about 30 wt. % ethanol, and optimally about 9 wt. % ethanol in the formulation concentrate of the aerosol.
  • the formulation comprises a perfume, a solvent or solvent/co-solvent mixture and a propellant.
  • perfume is used broadly to include, in general, all now known and hereafter devised fragrances and fragrance compositions (even compositions including identifiable amounts of other conventional compounds, e.g. DPG and the like).
  • perfumes are selected from the group of perfumes having viscosities at room temperature in the range of between about 10 and about 30 cps; these perfumes have been found to be particularly advantageous in the context of the present invention.
  • perfumes are selected which have viscosities (at room temperature) in the range of about 5 to about 50 cps, and more preferably in the range of about 10 to about 30 cps.
  • Acceptable aerosol compositions in the context of the present invention preferably include single-phase aerosol formulations comprising any suitable hydrocarbon propellant.
  • Preferred propellants include iso-butane, propane, and mixtures thereof.
  • a particularly preferred propellant comprises a blend of iso-butane and propane, and is available from Aeropres of Shreveport, LA under the designation A-60.
  • preferred fragrance compositions comprise single-phase aerosol formulations having between about 20 and about 90 wt. % of a propellant, about 20 to about 80 wt. % of a perfume and between about 0 and about 30 wt.% alcohol.
  • the propellant is present in amounts from about 25 to about 50 wt. %, more preferably about 30 to about 50 wt. %, and optimally 45 wt. %.
  • the perfume is present in an amount from about 25 to about 60 wt. %, more preferably from about 30 to about 60 wt. %, and optimally about 50 wt. %.
  • alcohol is present in an amount from about 2 to about 25 wt. %, more preferably about 2 to about 10 wt. %, and optimally about 5 wt. %.
  • a fragrance formulation in accordance with the first formulation embodiment of the present invention consists essentially of an aerosol composition having about 45 to about 50 wt. % of a propellant, about 50 to about 55 wt. % of a perfume having a viscosity of between about 10 and about 30 cps, and between about 5 and about 10% ethanol.
  • a fragrance formulation in accordance with this aspect of the present invention consists of about 45 wt. % propellant, about 50 wt. % of a perfume having a viscosity in the range of about 10 to about 30 cps, and about 5 wt. % ethanol.
  • the solvent or solvent/co-solvent mixture preferably comprises a composition which does not unduly depress the fragrance intensity of the particular perfume utilized, has good solvency for a wide range of perfume oils, has a generally low odor, has a generally low viscosity and has a generally low vapor pressure (e.g. less than 0J mm H g ).
  • the solvent and/or solvent/co-solvent mixture should generally be non-toxic, i.e. be of a substance which causes little or no eye and/or skin irritation and generally know acute toxicity in terms of ingestion.
  • the solvent or solvent/co-solvent mixture useful in the context of this second formulation embodiment of d e present invention may comprise any solvent now known or hereafter devised by those skilled in the art which substantially meets these solvent criteria.
  • the solvent utilized in preferred aerosol compositions in accordance with the second formulation embodiment of the present invention comprises fatty acid esters, isoparaffinic hydrocarbons, glycol ethers, glycols and/or mixtures thereof. More preferably, the solvent may comprise a fatty acid ester having a carbon chain between about C 12 and about C 16 is preferred. A particularly preferred fatty acid ester is isopropyl myristate having the general formula (CH 3 ) (CH 2 ) I2 CO 2 (CH 3 ) 2 . It should be recognized, however, that other saturated, or unsaturated fatty acid esters, particularly saturated fatty acid esters may be used in the context of the present invention.
  • Preferred isoparaffinic hydrocarbon solvents useful in accordance with the present invention comprise high-purity isoparaffinic materials, such as ISOPAR MTM (ISOPAR M is a trademark of Exxon Corp.). Other isoparaffinic materials such as those available under the trademark POLYSYNLANETM may also be used (POLYSYNLANE is a trademark of Polyespher Corp.).
  • Preferred glycol ethers include mono- and dialkyl-ethers of diethylene glycol, generally currently available under the trademark CARBITOLTM (CARBITOL is a trademark of Union Carbide Corp.). In addition, various glycols having the foregoing functional characteristics may also be utilized.
  • the solvent utilized in the aerosol compositions in accordance with this aspect of the second formulation embodiment of the present invention comprise a solvent/co-solvent mixture.
  • the co-solvent preferably comprises an alcohol.
  • Preferred alcohols include ethanol, isopropyl alcohol and mixtures thereof. Additional conventional solvents, for example dipropylene glycol and the like may also be used alone or in conjunction with the alcohol.
  • the co-solvent comprises a low chain alcohol, most preferably ethanol.
  • Solvent and/or co-solvent mixtures particularly useful in the context of this aspect of the present invention are preferably present in an amount from about 27 to about 90 wt. % of the aerosol composition.
  • the co-solvent which suitably comprises ethanol is present in an amount from about 0 to about 30 wt. % , more preferably from about 2 to about 25 wt. %, still more preferably from about 5 to about 15 wt. %, and optimally 5 to about 10 wt. %.
  • the solvent preferably isopropyl myristate, is present in an amount from about 25 to about 85 wt. % , more preferably from about 30 to about 60 wt. %, still more preferably from about 30 to about 56 wt. %, and optimally about 30 to about 35 wt. %.
  • preferred fragrance compositions comprise single-phase aerosol formulations having about between 10 to about 60 wt. % of a perfume, between about 27 to about 90 wt. % of a solvent or solvent/co-solvent mixture, and between about 15 and about 75 wt. % of a propellant.
  • the perfume is present in an amount from about 15 to about 50 wt. %, more preferably from about 20 to about 35 wt. %, and optimally about 25 to about 30 wt. %.
  • the solvent or solvent co-solvent mixture is present in an amount from about 27 to about 85 wt. % , more preferably about 30 to about 60 wt.
  • the propellant is present in an amount from about 24 to about 50 wt. % , more preferably about 30 to about 45 wt. % , and optimally about 40 to about 45 wt. %.
  • the following examples describe preferred exemplary embodiments of the present invention; these examples should not be interpreted as restricting the scope of the invention as defined in the accompanying claims. Unless otherwise specified, all parts and percentages in these examples are by weight.
  • fragrance formulations comprising varying amounts of perfume, ethanol, and dipropylene glycol (DPG), a commonly used perfume solvent, were evaluated for fragrance intensity.
  • DPG dipropylene glycol
  • a sensory panel comprising about 15 to 20 people was exposed to each of the following fragrance formulations in a specially designed room and asked to attribute a rating of the fragrance using a fixed scale, e.g. from zero (0) to eight (8), with 0 being a weak to non-existent fragrance and 8 being an extremely strong fragrance.
  • the room having a volume of 900 cubic feet (e.g.
  • apex 100 represents an aerosol concentrate mixture containing 100% of a perfume
  • apex 200 represents an aerosol concentrate of 50% perfume and 50% ethanol
  • apex 300 represents an aerosol concentrate of 50% perfume and 50% DPG.
  • the fragrance intensities plotted on this concentration matrix are shown using alpha characters where A represents a fragrance intensity of 1.500, B a fragrance intensity of 2.250, C a fragrance intensity of 3.000, D a fragrance intensity of 3.750, E a fragrance intensity of 4.500, and F a fragrance intensity of 5.250.
  • fragrance intensities in the range of or greater than about 3.5, preferably in the range of or greater than about 3.75, more preferably in the range of or greater than about 4.5, and optimally in the range of or greater than about 5.250.
  • Example 3 As illustration of the second fragrance formulation of the present invention, various fragrance formulations comprising varying amounts of perfume, solvent and/or solvent/co- solvent mixture and propellant were evaluated for fragrance intensity in the same manner as described in Example 1. Each of the fragrance compositions was dispensed from an aerosol container of the type described herein. In each case the perfume comprised a sweet floral fragrance. The results of these tests are set forth in Table 2. TABLE 2
  • Example 3 The various fragrance compositions set forth in Example 3 were further evaluated for longevity of fragrance intensity.
  • the fragrance intensity values for these compositions were therefore evaluated not only after initial dispensation, but also at 2 hour intervals for three intervals, i.e., at 2 hours, at 4 hours and at 6 hours.
  • the results are set forth in Table 3. TABLE 3
  • a preferable composition useful in the context of the present invention possesses a fragrance intensity after initial dispensing in die range of about 2.0 to 6.0, preferably about 4.0 to about 6.0. As shown, these formulations are preferably capable of maintaining a fragrance intensity of 3.0 to 4.5 after 2 hours, and a fragrance intensity of about 2.2 to about 4J after 6 hours.
  • preferred fragrance compositions have, with continued reference to Table 3, initial fragrance intensities preferably in the range of or greater than about 2.6, more preferably in the range of or greater than about 4.2, and optimally in the range of or greater than about 4.4.
  • These fragrance compositions suitably have desirable longevity characteristics such that the fragrance intensity of a preferred fragrance composition remains in the range of or greater than about 2.2, more preferably in the range of or greater than about 2.8 and optimally in the range of or greater than about 3.0 for at least 2 hours after initial dispensing.
  • fragrances other materials are or may be useful in connection with the present invention.
  • materials include but are not limited to deodorizers, biologically active disinfectants, bactericides, insecticides and insect repellents, insect pheromones, plant nutrient regulators and die like.
  • compositions in accordance wim the present invention have desirable fragrance intensities. While the mechanism underlying these results is not completely understood, it is possible that these enhanced fragrance intensity readings result from the improved dispersion of the perfume as enabled by the alcohol, solvent or solvent/co-solvent mixture carrier.
  • the alcohol, solvent or solvent/co-solvent mixture may cause the perfume to be dispersed in very fine particles in a rapid fashion such that the fragrance is readily dissipated into the air. Given the high quantity of perfume contained within the compositions and die fine dispersion of those compositions in the air surrounding apparatus 10, long-lasting fragrances are obtainable.
  • Container 20 preferably is provided widi a fragrance formulation having one of die foregoing compositions. Once so provided, container 20 is "loaded” into apparatus 10. In particular, and with reference to Figures 4 and 6, e loading of apparatus 10 and use of the loaded apparatus 10 will now be described.
  • tabs 46 and 48 are preferably provided widi sloping leading edges 96 and 98 which facilitate ease of insertion of container 20 into retainer 30.
  • Apparatus 10 is now ready for dispensing of die formulation contained within container 20.
  • actuating stem 24 is depressed, diereby causing release of the fragrance formulation dirough delivery aperture 26 to dispensing aperture 16 of upper portion 12.
  • a misting spray S is produced.
  • a metered amount of the fragrance composition is released through valve 22, thus ensuring that the air treating formulation is not wasted and me fragrance is optimally dispersed.
  • any residue which is collected from spray S or which remains from spray S can be collected in collection reservoir 18, dius preventing any residue from running down d e side of apparatus 10.
  • the perfume contained within the formulation is readily and widely dispersed in die air surrounding apparatus 10. This efficient dispersion tends to enhance longevity of the fragrance as well as intensity of the fragrance, as compared to results from other air freshener devices.
  • the useful life of container 20, and tiius apparatus 10 widi which it is used, is enhanced. Once die metered dose is released from valve 22, valve stem 24, and tiius upper portion 12, are returned to their normal closed positions. If desired (although generally not necessary), additional doses can be immediately obtained by again depressing upper portion 12 wid respect to lower portion 14.
  • container 20 can be directly removed from apparatus 10 in a fashion tiiat reverses the loading process described hereinabove.
  • tabs 46 and 48 can be manually separated and container 20 removed from housing 30 of apparatus 10.
  • tabs 46 and 48 are separated and die bottom portion of container 20 grasped by d e user and removed from apparatus 10.
  • upper portion 12 can be removed from lower portion 14 and container 20 removed from collar 40 by grasping valve 22 or die upper portion of container 20.
  • die bottom of lower portion 14 is provided widi a solid base 99. Loading of apparatus 10 in connection with this embodiment can be facilitated by removing upper portion 12, placing container 20 widiin collar 40 such diat it is retained in die bottom portion of retainer 30, and attaching upper portion 12 to lower portion 14 as described herein.
  • die invention is not limited to die specific forms shown herein.
  • the precise configuration of lower portion 14 and/or upper portion 12 can be modified as necessary to provide a suitable housing for die dispensing of die fragrance formulation disclosed herein.
  • die dimensions set forth herein are merely for the purpose of illustration and that the invention is not necessarily limited thereby.
  • diat die alcohol, solvent or co-solvent mixtures and/or perfumes usable in me context of die present invention can be modified to include otiier conventional aerosol additives, if desired.

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Le dispositif décrit dans cette invention comprend un récipient préssurisé (20) renfermant une composition de traitement de l'air hautement concentrée, ainsi qu'un diffuseur facile à utiliser (10), servant à diffuser cette composition. Ledit récipient (20) comporte une valve de dosage et une tige de valve pouvant être abaissée. Ledit diffuseur (10) comprend un premier logement (12), lequel présente une ouverture de diffusion (16) disposée de façon appropriée pour communiquer avec la tige de valve (24) du récipient (20), ainsi qu'un second logement (14) présentant un dispositif de fixation amovible (30) pour ledit récipient (20). Le premier logement (12) est mobile par rapport au second logement (14). Cette invention se rapporte également à un procédé de traitement de l'air, lequel consiste: 1) à prévoir un diffuseur qui comprend un dispositif destiné à recevoir de façon amovible une bombe aérosol, ainsi qu'un dispositif pour actionner cette bombe aérosol; 2) à prévoir une bombe aérosol contenant une composition de traitement de l'air concentrée; 3) à introduire cette bombe aérosol dans le diffuseur par actionnement du dispositif recevant la bombe aérosol amovible; et 4) à actionner la bombe aérosol pour libérer la composition de traitement de l'air. Selon cette invention, une première composition désodorisante comprend environ 20 à environ 50 % en poids d'un gas propulseur, environ 5 à environ 10 % en poids d'un alcool et environ 40 à environ 55 % en poids d'un parfum (de préférence environ 5 % en poids d'éthanol, environ 50 % en poids d'un parfum et environ 45 % en poids d'un gaz propulseur). Selon cette invention, une seconde composition désodorisante comprend environ 10 à environ 60 % en poids d'un parfum, environ 27 à environ 90 % en poids d'un solvant ou d'un mélange solvant/co-solvant et environ 15 à environ 75 % en poids d'un gaz propulseur (de préférence environ 5 % en poids d'éthanol, environ 30 % en poids d'isopropyl-myristate, environ 20 % en poids d'un parfum et environ 45 % en poids d'un gaz propulseur).
PCT/US1995/011557 1994-09-12 1995-09-12 Dispositif de traitement de l'air et procede d'utilisation de ce dispositif WO1996008425A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU35517/95A AU3551795A (en) 1994-09-12 1995-09-12 Air treatment device and method of using same

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30424294A 1994-09-12 1994-09-12
US08/304,242 1994-09-12
US47712395A 1995-06-08 1995-06-08
US08/477,123 1995-06-08

Publications (2)

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WO1996008425A3 WO1996008425A3 (fr) 1996-08-01

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AU (1) AU3551795A (fr)
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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2750844A1 (fr) * 1996-07-10 1998-01-16 Ppi Sa Dispositif de presentoir testeur
WO1998038114A1 (fr) 1997-02-28 1998-09-03 S.C. Johnson & Son, Inc. Generateur d'aerosol
WO1999066788A1 (fr) * 1998-06-24 1999-12-29 The Sherwin-Williams Company Desodorisation de litiere d'animal
EP1106171A1 (fr) * 1999-12-06 2001-06-13 Isabella Simbürger Compositions de parfum
WO2001056619A1 (fr) * 2000-01-31 2001-08-09 Reckitt Benckiser (Uk) Limited Compositions d'assainisseur d'air liquide ou d'insecticide et leurs utilisations
EP1245221A1 (fr) * 2001-03-23 2002-10-02 Haarmann & Reimer Gmbh Additif de mouillage
WO2007052016A2 (fr) * 2005-11-01 2007-05-10 Reckitt Benckiser (Uk) Limited Procede et composition d'aerosol
WO2009067187A1 (fr) * 2007-11-20 2009-05-28 S. C. Johnson & Son, Inc. Composition concentrée de parfum distribuée en bombe d'aérosol dosé
EP2233214A1 (fr) * 2009-03-27 2010-09-29 S.C. Johnson & Son, Inc. Distributeur d'aérosol
WO2012015381A1 (fr) * 2010-07-30 2012-02-02 S. C. Johnson & Son, Inc. Adaptateur pour un distributeur
US8475769B2 (en) 2010-06-25 2013-07-02 S.C. Johnson & Son, Inc. Aerosol composition with enhanced dispersion effects
WO2017046615A1 (fr) * 2015-09-18 2017-03-23 Reckitt Benckiser (Brands) Limited Dispositif de pulvérisation
US10322198B2 (en) 2016-07-08 2019-06-18 The Procter & Gamble Company Freshening compositions comprising isopropyl myristate

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1831088A1 (fr) * 2004-12-03 2007-09-12 Multi-Vet Ltd. Systeme d'aministration de fluide utilise pour administrer une substance active sous forme d'aerosol
WO2007124554A1 (fr) * 2006-04-28 2007-11-08 Multi-Vet Ltd. Dispositif de distribution programmable pour système de distribution de fluide

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2607627A (en) * 1950-11-20 1952-08-19 Tappan Stove Co Liquid dispensing gun
US2998165A (en) * 1959-02-05 1961-08-29 Elorza John De Pressure container for perfume spray
DE1491714A1 (de) * 1964-11-11 1969-05-08 Fisons Pharmaceuticals Ltd Vorrichtung an einem Aerosol-Druckbehaelter
US3479297A (en) * 1963-08-08 1969-11-18 Bohme Fettchemie Gmbh Room deodorants
US3549055A (en) * 1967-07-04 1970-12-22 Sterling Drug Inc Aerosol clam shell dispenser
US4226340A (en) * 1978-08-15 1980-10-07 Louis Troesch Tissue treatment dispenser
JPS5964688A (ja) * 1982-10-05 1984-04-12 Johnson Kk エアゾ−ル組成物
DE3347742A1 (de) * 1983-12-30 1985-07-11 IG Sprühtechnik GmbH, 7867 Wehr Geruchloeschendes spray
AU553911B2 (en) * 1982-06-23 1986-07-31 Clean-A-Matic Pty Limited Air deodorising device
FR2594714A1 (fr) * 1986-02-26 1987-08-28 Oreal Dispositif distributeur-diffuseur de substances volatiles, notamment de desodorisants d'atmosphere
WO1992004419A1 (fr) * 1990-09-03 1992-03-19 Soltec Research Pty. Ltd. Aerosol concentre a pulverisation dans l'air ambiant
US5358147A (en) * 1993-09-02 1994-10-25 S. C. Johnson & Son, Inc. Spray dispensing package

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2607627A (en) * 1950-11-20 1952-08-19 Tappan Stove Co Liquid dispensing gun
US2998165A (en) * 1959-02-05 1961-08-29 Elorza John De Pressure container for perfume spray
US3479297A (en) * 1963-08-08 1969-11-18 Bohme Fettchemie Gmbh Room deodorants
DE1491714A1 (de) * 1964-11-11 1969-05-08 Fisons Pharmaceuticals Ltd Vorrichtung an einem Aerosol-Druckbehaelter
US3549055A (en) * 1967-07-04 1970-12-22 Sterling Drug Inc Aerosol clam shell dispenser
US4226340A (en) * 1978-08-15 1980-10-07 Louis Troesch Tissue treatment dispenser
AU553911B2 (en) * 1982-06-23 1986-07-31 Clean-A-Matic Pty Limited Air deodorising device
JPS5964688A (ja) * 1982-10-05 1984-04-12 Johnson Kk エアゾ−ル組成物
DE3347742A1 (de) * 1983-12-30 1985-07-11 IG Sprühtechnik GmbH, 7867 Wehr Geruchloeschendes spray
FR2594714A1 (fr) * 1986-02-26 1987-08-28 Oreal Dispositif distributeur-diffuseur de substances volatiles, notamment de desodorisants d'atmosphere
WO1992004419A1 (fr) * 1990-09-03 1992-03-19 Soltec Research Pty. Ltd. Aerosol concentre a pulverisation dans l'air ambiant
US5358147A (en) * 1993-09-02 1994-10-25 S. C. Johnson & Son, Inc. Spray dispensing package

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 008, no. 162 (C-235), 26 July 1984 & JP,A,59 064688 (JIYONSON KK), 12 April 1984, *

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2750844A1 (fr) * 1996-07-10 1998-01-16 Ppi Sa Dispositif de presentoir testeur
WO1998038114A1 (fr) 1997-02-28 1998-09-03 S.C. Johnson & Son, Inc. Generateur d'aerosol
WO1999066788A1 (fr) * 1998-06-24 1999-12-29 The Sherwin-Williams Company Desodorisation de litiere d'animal
US6253710B1 (en) 1998-06-24 2001-07-03 The Sherwin-Williams Company Odor control for animal litter
EP1106171A1 (fr) * 1999-12-06 2001-06-13 Isabella Simbürger Compositions de parfum
WO2001041728A1 (fr) * 1999-12-06 2001-06-14 Simbuerger Isabella Formulation de fragrance ou de parfum
WO2001056619A1 (fr) * 2000-01-31 2001-08-09 Reckitt Benckiser (Uk) Limited Compositions d'assainisseur d'air liquide ou d'insecticide et leurs utilisations
GB2358586B (en) * 2000-01-31 2002-05-01 Reckitt & Colmann Prod Ltd Improvements in or relating to compositions
US7018644B2 (en) 2000-01-31 2006-03-28 Reckitt Benckiser (Uk) Limited Liquid air freshener and insecticidal compositions and device for using same
EP1245221A1 (fr) * 2001-03-23 2002-10-02 Haarmann & Reimer Gmbh Additif de mouillage
WO2007052016A2 (fr) * 2005-11-01 2007-05-10 Reckitt Benckiser (Uk) Limited Procede et composition d'aerosol
WO2007052016A3 (fr) * 2005-11-01 2007-11-15 Reckitt Benckiser Uk Ltd Procede et composition d'aerosol
WO2009067187A1 (fr) * 2007-11-20 2009-05-28 S. C. Johnson & Son, Inc. Composition concentrée de parfum distribuée en bombe d'aérosol dosé
CN102414091B (zh) * 2009-03-27 2014-03-19 约翰逊父子公司 雾化分配器
EP2236435A1 (fr) * 2009-03-27 2010-10-06 S. C. Johnson & Son, Inc. Distributeur d'aérosol
CN102414091A (zh) * 2009-03-27 2012-04-11 约翰逊父子公司 雾化分配器
EP2233214A1 (fr) * 2009-03-27 2010-09-29 S.C. Johnson & Son, Inc. Distributeur d'aérosol
EP2684612A3 (fr) * 2009-03-27 2014-10-22 S.C.Johnson & Son, Inc. Distributeur d'aérosol
US8475769B2 (en) 2010-06-25 2013-07-02 S.C. Johnson & Son, Inc. Aerosol composition with enhanced dispersion effects
WO2012015381A1 (fr) * 2010-07-30 2012-02-02 S. C. Johnson & Son, Inc. Adaptateur pour un distributeur
US8474663B2 (en) 2010-07-30 2013-07-02 S.C. Johnson & Son, Inc. Adapter for a dispenser
WO2017046615A1 (fr) * 2015-09-18 2017-03-23 Reckitt Benckiser (Brands) Limited Dispositif de pulvérisation
CN108025859A (zh) * 2015-09-18 2018-05-11 雷克特本克斯尔(品牌)有限公司 喷射装置
US10442605B2 (en) 2015-09-18 2019-10-15 Reckitt Benckiser (Brands) Limited Spraying device
CN108025859B (zh) * 2015-09-18 2020-01-31 雷克特本克斯尔(品牌)有限公司 喷射装置
US10322198B2 (en) 2016-07-08 2019-06-18 The Procter & Gamble Company Freshening compositions comprising isopropyl myristate

Also Published As

Publication number Publication date
MX9701885A (es) 1998-07-31
AU3551795A (en) 1996-03-29
CA2199736A1 (fr) 1996-03-21
WO1996008425A3 (fr) 1996-08-01

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