WO1995009157A1 - Derive d'azole et composition pharmaceutique le contenant - Google Patents
Derive d'azole et composition pharmaceutique le contenant Download PDFInfo
- Publication number
- WO1995009157A1 WO1995009157A1 PCT/JP1994/001593 JP9401593W WO9509157A1 WO 1995009157 A1 WO1995009157 A1 WO 1995009157A1 JP 9401593 W JP9401593 W JP 9401593W WO 9509157 A1 WO9509157 A1 WO 9509157A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- group
- formula
- different
- same
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/619,629 US5807880A (en) | 1993-09-30 | 1994-09-28 | Azole derivative and pharmaceutical composition thereof |
AU77071/94A AU679119B2 (en) | 1993-09-30 | 1994-09-28 | Azole derivative and pharmaceutical composition thereof |
EP94927788A EP0721943A4 (en) | 1993-09-30 | 1994-09-28 | AZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME |
KR1019960701595A KR960704852A (ko) | 1993-09-30 | 1994-09-28 | 아졸 유도체 및 이의 약제학적 조성물 (Azole derivative and pharmaceutical composition thereof) |
NO961274A NO961274L (no) | 1993-09-30 | 1996-03-29 | Azolderivat og farmasöytiske preparat derav |
FI961418A FI961418A (fi) | 1993-09-30 | 1996-03-29 | Atsolijohdannainen ja sen farmaseuttinen seos |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5/244944 | 1993-09-30 | ||
JP24494493 | 1993-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1995009157A1 true WO1995009157A1 (fr) | 1995-04-06 |
Family
ID=17126291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1994/001593 WO1995009157A1 (fr) | 1993-09-30 | 1994-09-28 | Derive d'azole et composition pharmaceutique le contenant |
Country Status (12)
Country | Link |
---|---|
US (1) | US5807880A (ja) |
EP (1) | EP0721943A4 (ja) |
KR (1) | KR960704852A (ja) |
CN (1) | CN1131944A (ja) |
AU (1) | AU679119B2 (ja) |
CA (1) | CA2170874A1 (ja) |
FI (1) | FI961418A (ja) |
HU (1) | HUT75871A (ja) |
NO (1) | NO961274L (ja) |
NZ (1) | NZ273681A (ja) |
PL (1) | PL313769A1 (ja) |
WO (1) | WO1995009157A1 (ja) |
Cited By (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998037070A1 (fr) * | 1997-02-21 | 1998-08-27 | Takeda Chemical Industries, Ltd. | Composes a anneaux condenses, leur procede de production et leur utilisation |
WO1999018075A1 (fr) * | 1997-10-02 | 1999-04-15 | Yukijirushi Nyugyo Kabushiki Kaisha | Nouveaux composes a base de dihydronaphtalene et leur procede de production |
WO2002046186A1 (fr) | 2000-12-08 | 2002-06-13 | Takeda Chemical Industries, Ltd. | Dérivés thiazole substitués porteurs de groupes 3-pyridyl, procédé d'élaboration et leur utilisation |
US6518423B1 (en) | 1996-08-09 | 2003-02-11 | Eisai Co., Ltd. | Benzopiperidine derivatives |
EP1681290A2 (en) | 2000-11-17 | 2006-07-19 | Takeda Pharmaceutical Company Limited | Imidazole derivatives, production method thereof and use thereof |
WO2010149755A1 (en) | 2009-06-26 | 2010-12-29 | Novartis Ag | 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17 |
WO2012035078A1 (en) | 2010-09-16 | 2012-03-22 | Novartis Ag | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS |
WO2012149413A1 (en) | 2011-04-28 | 2012-11-01 | Novartis Ag | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS |
JP2014031339A (ja) * | 2012-08-03 | 2014-02-20 | Kao Corp | StAR発現抑制剤 |
JP2014125444A (ja) * | 2012-12-26 | 2014-07-07 | Ne Chemcat Corp | カルバゾール類の製造方法およびこの方法により製造されたカルバゾール類。 |
WO2014158875A1 (en) | 2013-03-14 | 2014-10-02 | Pellficure Pharmaceuticals Inc. | Novel therapy for prostate carcinoma |
US9655868B2 (en) | 2010-08-04 | 2017-05-23 | Pellficure Pharmaceuticals, Inc. | Treatment of prostate carcinoma |
WO2018080933A1 (en) | 2016-10-24 | 2018-05-03 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
US10093620B2 (en) | 2014-09-12 | 2018-10-09 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
JP2021526157A (ja) * | 2018-04-27 | 2021-09-30 | チョンドゥー ホンハオ インベストメント カンパニー リミテッド | 10h−フェノチアジン系フェロトーシス阻害剤、その製造方法、及び用途 |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6559157B2 (en) | 1997-10-02 | 2003-05-06 | Daiichi Pharmaceutical Co., Ltd. | Dihydronaphthalene compounds |
JP4546589B2 (ja) * | 1998-04-23 | 2010-09-15 | 武田薬品工業株式会社 | ナフタレン誘導体 |
EP1073640B1 (en) | 1998-04-23 | 2005-04-13 | Takeda Pharmaceutical Company Limited | Naphthalene derivatives, their production and use |
PE20010781A1 (es) * | 1999-10-22 | 2001-08-08 | Takeda Chemical Industries Ltd | Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion |
WO2001030764A1 (fr) | 1999-10-22 | 2001-05-03 | Takeda Chemical Industries, Ltd. | Alcools de phenyl-1-(1h-imidazol-4-yl) substitues en position 1, procede de preparation et utilisation de ces derniers |
JP4520012B2 (ja) * | 1999-10-22 | 2010-08-04 | 武田薬品工業株式会社 | 1−置換−1−(1h−イミダゾール−4−イル)メタノール類 |
CA2429437A1 (en) | 2000-11-20 | 2002-05-23 | Takeda Chemical Industries, Ltd. | Imidazole derivatives, process for their preparation and their use |
EP1607092A4 (en) * | 2003-03-17 | 2010-12-15 | Takeda Pharmaceutical | CONTROLLED RELEASE COMPOSITIONS |
WO2008021250A2 (en) * | 2006-08-10 | 2008-02-21 | Fred Hutchinson Cancer Research Center | Compositions and methods for modulating apoptosis in cells over-expressing bcl-2 family member proteins |
WO2011041731A2 (en) | 2009-10-02 | 2011-04-07 | Fred Hutchinson Cancer Research Center | Method of inhibiting bcl-2-related survival proteins |
WO2011041737A2 (en) | 2009-10-02 | 2011-04-07 | Fred Hutchinson Cancer Research Center | Gain-of-function bcl-2 inhibitors |
AU2011343966B2 (en) * | 2010-12-13 | 2017-03-16 | Innocrin Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
CN109748884B (zh) * | 2019-02-19 | 2022-06-24 | 成都恒昊创新科技有限公司 | 一种铁死亡抑制剂及其制备方法与应用 |
WO2021098715A1 (zh) * | 2019-11-21 | 2021-05-27 | 成都恒昊投资有限公司 | 一种吩噻嗪类铁死亡抑制剂及其制备方法和用途 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0433813A2 (de) * | 1989-12-21 | 1991-06-26 | Bayer Ag | Triarylmethan-Farbbildner |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ221729A (en) * | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
GB9310635D0 (en) * | 1993-05-21 | 1993-07-07 | Glaxo Group Ltd | Chemical compounds |
WO1995004723A1 (fr) * | 1993-08-04 | 1995-02-16 | Yamanouchi Pharmaceutical Co., Ltd. | Derive d'imidazolylalkylamine et composition pharmaceutique contenant ledit derive |
-
1994
- 1994-09-28 US US08/619,629 patent/US5807880A/en not_active Expired - Fee Related
- 1994-09-28 NZ NZ273681A patent/NZ273681A/en unknown
- 1994-09-28 PL PL94313769A patent/PL313769A1/xx unknown
- 1994-09-28 AU AU77071/94A patent/AU679119B2/en not_active Ceased
- 1994-09-28 WO PCT/JP1994/001593 patent/WO1995009157A1/ja not_active Application Discontinuation
- 1994-09-28 HU HU9600813A patent/HUT75871A/hu unknown
- 1994-09-28 EP EP94927788A patent/EP0721943A4/en not_active Withdrawn
- 1994-09-28 KR KR1019960701595A patent/KR960704852A/ko not_active Application Discontinuation
- 1994-09-28 CA CA002170874A patent/CA2170874A1/en not_active Abandoned
- 1994-09-28 CN CN94193503A patent/CN1131944A/zh active Pending
-
1996
- 1996-03-29 NO NO961274A patent/NO961274L/no unknown
- 1996-03-29 FI FI961418A patent/FI961418A/fi unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0433813A2 (de) * | 1989-12-21 | 1991-06-26 | Bayer Ag | Triarylmethan-Farbbildner |
Non-Patent Citations (2)
Title |
---|
J. INDIAN CHEM. SOC., Vol. 61, No. 7, (1984), pages 611 to 613. * |
See also references of EP0721943A4 * |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6518423B1 (en) | 1996-08-09 | 2003-02-11 | Eisai Co., Ltd. | Benzopiperidine derivatives |
WO1998037070A1 (fr) * | 1997-02-21 | 1998-08-27 | Takeda Chemical Industries, Ltd. | Composes a anneaux condenses, leur procede de production et leur utilisation |
US6420375B1 (en) | 1997-02-21 | 2002-07-16 | Takeda Chemical Industries, Ltd. | Fused ring compounds, process for producing the same and use thereof |
WO1999018075A1 (fr) * | 1997-10-02 | 1999-04-15 | Yukijirushi Nyugyo Kabushiki Kaisha | Nouveaux composes a base de dihydronaphtalene et leur procede de production |
EP1681290A2 (en) | 2000-11-17 | 2006-07-19 | Takeda Pharmaceutical Company Limited | Imidazole derivatives, production method thereof and use thereof |
WO2002046186A1 (fr) | 2000-12-08 | 2002-06-13 | Takeda Chemical Industries, Ltd. | Dérivés thiazole substitués porteurs de groupes 3-pyridyl, procédé d'élaboration et leur utilisation |
WO2010149755A1 (en) | 2009-06-26 | 2010-12-29 | Novartis Ag | 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17 |
US9655868B2 (en) | 2010-08-04 | 2017-05-23 | Pellficure Pharmaceuticals, Inc. | Treatment of prostate carcinoma |
US9877932B2 (en) | 2010-08-04 | 2018-01-30 | Pellficure Pharmaceuticals, Inc. | Treatment of prostate carcinoma |
US10245240B2 (en) | 2010-08-04 | 2019-04-02 | Pellficure Pharmaceuticals, Inc. | Treatment of prostate carcinoma |
WO2012035078A1 (en) | 2010-09-16 | 2012-03-22 | Novartis Ag | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS |
WO2012149413A1 (en) | 2011-04-28 | 2012-11-01 | Novartis Ag | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS |
JP2014031339A (ja) * | 2012-08-03 | 2014-02-20 | Kao Corp | StAR発現抑制剤 |
JP2014125444A (ja) * | 2012-12-26 | 2014-07-07 | Ne Chemcat Corp | カルバゾール類の製造方法およびこの方法により製造されたカルバゾール類。 |
WO2014158875A1 (en) | 2013-03-14 | 2014-10-02 | Pellficure Pharmaceuticals Inc. | Novel therapy for prostate carcinoma |
US10093620B2 (en) | 2014-09-12 | 2018-10-09 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
US10577315B2 (en) | 2014-09-12 | 2020-03-03 | Pellficure Pharmaceuticals, Inc. | Compositions and methods for treatment of prostate carcinoma |
WO2018080933A1 (en) | 2016-10-24 | 2018-05-03 | Pellficure Pharmaceuticals Inc. | Pharmaceutical compositions of 5-hydroxy-2-methylnaphthalene-1, 4-dione |
JP2021526157A (ja) * | 2018-04-27 | 2021-09-30 | チョンドゥー ホンハオ インベストメント カンパニー リミテッド | 10h−フェノチアジン系フェロトーシス阻害剤、その製造方法、及び用途 |
Also Published As
Publication number | Publication date |
---|---|
AU7707194A (en) | 1995-04-18 |
NO961274D0 (no) | 1996-03-29 |
CA2170874A1 (en) | 1995-04-06 |
NZ273681A (en) | 1996-09-25 |
FI961418A0 (fi) | 1996-03-29 |
EP0721943A4 (en) | 1996-09-04 |
NO961274L (no) | 1996-03-29 |
US5807880A (en) | 1998-09-15 |
EP0721943A1 (en) | 1996-07-17 |
PL313769A1 (en) | 1996-07-22 |
HU9600813D0 (en) | 1996-05-28 |
CN1131944A (zh) | 1996-09-25 |
AU679119B2 (en) | 1997-06-19 |
FI961418A (fi) | 1996-03-29 |
KR960704852A (ko) | 1996-10-09 |
HUT75871A (en) | 1997-05-28 |
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