WO1995005862A1 - Catheter - Google Patents

Catheter Download PDF

Info

Publication number
WO1995005862A1
WO1995005862A1 PCT/GB1994/001841 GB9401841W WO9505862A1 WO 1995005862 A1 WO1995005862 A1 WO 1995005862A1 GB 9401841 W GB9401841 W GB 9401841W WO 9505862 A1 WO9505862 A1 WO 9505862A1
Authority
WO
WIPO (PCT)
Prior art keywords
catheter
aperture
tip
catheter according
restrictor
Prior art date
Application number
PCT/GB1994/001841
Other languages
English (en)
Inventor
Man Fai Shiu
Original Assignee
Man Fai Shiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Man Fai Shiu filed Critical Man Fai Shiu
Priority to EP94924917A priority Critical patent/EP0715529A1/fr
Priority to JP7507428A priority patent/JPH09501597A/ja
Publication of WO1995005862A1 publication Critical patent/WO1995005862A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0074—Dynamic characteristics of the catheter tip, e.g. openable, closable, expandable or deformable
    • A61M25/0075—Valve means
    • A61M2025/0076—Unidirectional valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/008—Strength or flexibility characteristics of the catheter tip
    • A61M2025/0081—Soft tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked

Definitions

  • This invention relates to a catheter intended primarily for contrast angiography and interventional procedures. It was devised with a view to improving safety and efficacy in procedures in the coronary arteries but may have application in all arterial work such as neuro-radiology and peripheral arterial work. It is to be understood that the present invention does not relate to all forms of medical catheters, for example urological catheters, but only to those for use in blood vessels.
  • the wire is soft tipped often with a small curved tip to reduce trauma during catheter advance and positioning. This allows preliminary exploration of curved and diseased arteries for example.
  • the wire also serves the function for example with the pre-formed shaped Judkins catheter of straightening out the catheter as it is passed into position. Finally, the use of a wire allows the exchange of catheters without the loss of access to the same artery or arterial segment.
  • catheters of the second type referred to above having side holes only, lose the advantages of accommodating the introducing wire.
  • the first type of catheter having an end hole, does have certain disadvantages.
  • the end hole tends to have a sharp edge which can injure the walls of the blood vessel during positioning of the catheter.
  • the forceful injection of contrast medium may also have a traumatic effect on the vessel wall because the contrast medium emerges as a single forwardly directed forceful jet. In a small number of cases, perhaps 0.3%, dissection of the arterial wall can occur, with serious risk to the patient.
  • Imaging can also be defective as the contrast medium can tend to issue in a stream along the lumen of the artery, giving an indistinct image of the vessel wall. If the artery branches, the injected medium may subselect one of two or three branches, giving poor or indeed no imaging of the other branches.
  • a single end hole allows precise position for pressure measurements and in certain circumstances, precise injection of contrast, although the need for the latter is rare. Conversely, however, if the single end hole is positioned in abutment with an arterial wall, pressure monitoring ceases and injection of contrast medium can prove dangerous.
  • Catheters of the second type, having side holes only, are recognised to have a higher degree of safety because there is no sharp tip and they are therefore less traumatic during manoeuvring. Injection of contrast medium through the catheter gives better imaging because the contrast medium sprays laterally outwardly from the catheter, showing the contours of the arterial wall and picking up any local side branches. There is also less tendency for the side hole only catheter to recoil from its chosen position during injection. However such catheters have the major disadvantage that they cannot be deployed over a wire and need other techniques, for example the use of a guide catheter or sheath to position them.
  • a catheter having a hollow lumen having a distal end provided with a tip for insertion into a blood vessel, a plurality of peripherally spaced holes closely adjacent the tip, the tip having a terminal aperture capable of adopting two configurations, namely an enlarged wire carrying configuration in which it is capable of receiving and passing a wire, and a restricted configuration in which it is of substantially smaller cross- sectional area than in the enlarged condition, the aperture being normally biased into said restricted configuration.
  • the terminal aperture may comprise a slit or a plurality of intersecting slits.
  • the aperture may be provided with a resilient peripheral restrictor which may comprise an annulus of resilient material surrounding and at least partly closing the aperture or which may comprise a plurality of inwardly projecting resilient restrictor members which at least partly close the aperture.
  • the resilient peripheral restrictor may comprise latex or silicone rubber.
  • the catheter may be coated with the same material as forms the resilient peripheral restrictor.
  • the aperture may comprise a valve openable by a wire.
  • the catheter may comprise a diagnostic coronary angiogram catheter or may comprise a guiding catheter for interventional procedures such as PTCA.
  • Figure 1 shows a prior art catheter tip having a terminal aperture
  • Figure 2 shows a prior art catheter tip having side apertures but no terminal aperture.
  • Figure 3A shows a prior art catheter tip having a terminal aperture and side apertures at a distance from the tip.
  • Figure 3B shows a prior art catheter similar to that in Figure 3A but with side apertures close to the tip.
  • Figure 4 shows a prior art Judkins type catheter having a terminal aperture.
  • Figure 5 shows the present invention applied to a Judkins type catheter.
  • Figure 6 is an enlarged detail view of the tip of the catheter shown in Figure 5 with a tip aperture in a restricted configuration
  • Figure 6A is a detail end view of the tip shown in Figure 6,
  • Figure 7 shows the catheter of Figure 5 with the tip aperture in an enlarged wire carrying configuration.
  • Figure 8 illustrates an alternative form of tip in cross- section in the normal restricted configuration.
  • Figure 8A is a detail end view of the tip shown in Figure 8,
  • Figure 8B is a detail end view of a still further alternative of the tip shown in Figure 8,
  • Figure 9 illustrates the tip of Figure 8 in the enlarged wire carrying configuration.
  • Figure 10 illustrates the catheter tip of Figures 8 and 9 in use during contrast angiography, illustrating ease of visualisation of small side branches.
  • Figure 1 shows the tip 10 of a catheter having an end hole 11 which is of the same internal diameter as the lumen of the catheter.
  • This is a type of catheter exemplified by the Judkins left and right catheters such as that illustrated in Figure 4.
  • this type of catheter can be used in combination with an introducing or guide wire by well known techniques. The use of the guide wire enables it to be positioned accurately.
  • the tip aperture 11 has a relatively sharp edge which may cause trauma.
  • Figure 2 shows diagrammatically a form of catheter 13 which has a closed end 14 which is of rounded configuration.
  • This catheter has a plurality of side holes 15 arranged peripherally near to the tip 14.
  • the NIH catheter is a typical example of the type of catheter shown in Figure 2.
  • FIGS 3A and 3B The third form of prior art catheter is illustrated in Figures 3A and 3B comprises a catheter 16 having an end hole 17 similar to the end hole 11 of Figure 1 and also has a plurality of side holes 18 which, however, are either spaced by a distance of perhaps 2 cm to 3 cm from the distal tip and the end hole 17 (Figure 3A) or close to the tip ( Figure 3B) .
  • a wire can be used for positioning the catheter.
  • the extreme free end of the tip portion 23 has a terminal aperture in the form of three slits meeting at a point as shown in Figure 6A.
  • This construction is by way of example and it would be possible to provide more or fewer slits or even a single slit provided that the aperture is capable of adopting two configurations.
  • the actual aperture has a very small cross-sectional area and this is the normal condition. In other words, the aperture is biased into this restricted configuration. This may be a result of the nature of the materials of which the catheter is made or of some mechanical constraint.
  • a guide wire 24 has been passed into a suitable position in a blood vessel and the catheter 22 has been slid along the guide wire until it is in its correctly deployed condition.
  • the tip 23 has its aperture 25 opened up so that each of the slits 26 spreads apart and the effective cross-sectional area of the aperture is enlarged.
  • the wire 24 may be withdrawn and, as this is done, the slits 26 resiliently re-close the aperture 25 to the restricted condition shown in Figure 6.
  • catheter 22 has side holes 27, a plurality of which are provided very closely adjacent the tip aperture 25.
  • certain open ended catheters of the type shown in Figure 1 have a "soft tip" made of elastic material as opposed to the firm material used in the main core of the body of the catheter.
  • a firm core 29 is surrounded by a coating of suitably elastic material 30 such as latex or silicone rubber which extends at the tip to form a resilient peripheral restrictor 31, restricting the aperture 40 at the tip by reducing the normal internal diameter of the catheter lumen 32 to a closed or virtually closed condition under normal circumstances.
  • This restricted configuration is as illustrated in Figure 8.
  • the peripheral restrictor 31 is annular in shape ( Figure 8B) although it could possibly comprise a number of inwardly directed relatively localised restrictor members 33 which tend to partly close up the aperture 40 in the normal restricted condition as illustrated in Figure 8A.
  • Figure 9 shows the catheter 28 of Figure 8 with a guide wire 34 deployed.
  • the aperture 40 defined by the peripheral restrictor 31 has been resiliently opened so that the terminal aperture 40 adopts an enlarged wire carrying configuration.
  • the internal diameter of the lumen 32 may conform very closely to the external diameter of the wire 34 but preferably provides a small clearance as shown. This means that the resilient peripheral restrictor 31 is a snug fit around the wire.
  • the device is illustrated in Figure 10.
  • the catheter 28 is shown positioned within an artery whose wall is indicated at 35. It will be seen that the artery 35 is bifurcated into a main branch 36 and a small side branch 37 in this example. This figure will illustrate more clearly the effectiveness of the present invention.
  • the catheter of Figures 8 to 10 has a plurality of side holes 38, again peripherally spaced around the catheter and close to the extreme tip and its terminal aperture.
  • peripheral side holes 38 provided in the catheter of the present invention, together with the restricted tip aperture 40, a "spray” effect is achieved with the contrast medium which spreads out into both the main artery 36 and the small side branch 37, tending to billow and cling to the walls and highlight the contours in a very advantageous way.
  • the terminal aperture 40 at the tip 39 will be in its restricted configuration and may be closed or almost closed during injection. However it may be helpful if some portion of the injected medium emanates from the tip aperture as well as through the side holes 38 since this gives the best pattern of contrast medium.
  • the invention is used in exactly the same way as the existing catheter of the same type so no new techniques need to be learned by the physician. It can be positioned using a guide wire.
  • the procedure time is shortened. Repeated imaging is not necessary because the "spray effect" of the contrast medium from the catheter provides much better images.
  • the positional stability of the catheter is greatly improved during forced injection of contrast medium. There is little or no recoil detectable.
  • the conventional end hole only catheter may lodge primarily in the left anterior descending artery, giving rise to poor or even no imaging of the circumflex artery for example.
  • the catheter tip does not cause disruption of plaque. This is again due to the relative spreading of the contrast medium on injection.
  • PTCA percutaneous transluminal coronary angioplasty
  • a guiding catheter is positioned using a guide wire.
  • the guide catheter is left in position and a small balloon catheter is fed through it so that the balloon can be positioned within a constricted portion of artery, where it is inflated to expand the lumen of the artery.
  • Guide catheters used for PTCA are usually soft tip catheters having an end hole only. The soft tip is useful because of the slightly larger size of the catheters, and the need to avoid damage not merely to the patients tissue but also to the very delicate balloon catheter as it is passed.
  • a catheter having the features of the present invention namely side holes close to the tip and a self-closing or self-restricting tip aperture
  • substantial advantages can be gained.
  • the manoeuvring of the guide catheter can be safely achieved due to the capability of using a guide wire.
  • the wire can be removed and the balloon catheter passed without any alteration in the standard techniques currently adopted.
  • the imaging available would be considerably better for the reasons outlined above in connection with angiography.
  • the peripheral restrictor or tip construction is sufficiently compliant, the passage of the balloon catheter would be unimpeded with possibly some slight increase in resistance.
  • the form of resilient peripheral restrictor which is annular in shape as illustrated in Figure 8B may provide the best arrangement for a PTCA guide catheter rather than the form shown in Figure 8A or the slit type arrangement shown in Figure 6A.
  • the catheter could be used for other interventional procedures for example insertion of stents.
  • Catheter devices as set out in the claims of this application may be adapted for use in other circumstances such as for example neuro-radiology or peripheral arterial work.

Abstract

Ce cathéter (22, 28) comporte une lumière creuse dont l'extrémité distale est pourvue d'une pointe (23, 29) destinée à l'insertion dans un vaisseau sanguin, et une pluralité de trous (27, 28) espacés sur la périphérie à proximité de la pointe (23, 39). La pointe possède une ouverture terminale (25, 40) qui peut prendre deux configurations, à savoir une configuration élargie de support du fil, dans laquelle elle peut recevoir et faire passer un fil (24, 34), et une configuration rétrécie dans laquelle elle présente une surface en section sensiblement plus petite que dans l'état élargi, l'ouverture (25, 40) étant normalement précontrainte dans cette configuration rétrécie. L'ouverture (25, 40) peut comporter une fente ou une pluralité de fentes (26) ou un dispositif de restriction périphérique (31, 33) prenant la forme d'un anneau, ou une pluralité d'éléments de restriction en matériau élastique tel qu'un caoutchouc au latex ou au silicone. Ce cathéter, destiné à être utilisé dans des vaisseaux sanguins, peut être utilisé dans les interventions sur les coronaires, par exemple l'angiographie coronarienne ou les procédures d'intervention telles que l'angioplastie par ballonnet ou l'insertion de stents, ainsi que pour d'autres interventions artérielles.
PCT/GB1994/001841 1993-08-24 1994-08-23 Catheter WO1995005862A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP94924917A EP0715529A1 (fr) 1993-08-24 1994-08-23 Catheter
JP7507428A JPH09501597A (ja) 1993-08-24 1994-08-23 カテーテル

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9317539.6 1993-08-24
GB939317539A GB9317539D0 (en) 1993-08-24 1993-08-24 Catheter

Publications (1)

Publication Number Publication Date
WO1995005862A1 true WO1995005862A1 (fr) 1995-03-02

Family

ID=10740917

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1994/001841 WO1995005862A1 (fr) 1993-08-24 1994-08-23 Catheter

Country Status (4)

Country Link
EP (1) EP0715529A1 (fr)
JP (1) JPH09501597A (fr)
GB (1) GB9317539D0 (fr)
WO (1) WO1995005862A1 (fr)

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1000678C2 (en) * 1995-06-28 1996-12-31 Cordis Europ Catheter with hose-shaped basic body and distal end
EP0874653A1 (fr) * 1995-12-14 1998-11-04 Medtronic, Inc. Dispositif et procede pour administrer de maniere selective un fluide dans une lumiere anatomique
EP0998321A4 (fr) * 1996-08-01 2000-05-10 Gerald S Linder Conduit d'intubation nasale et procede d'utilisation
EP1595565A1 (fr) * 2004-05-14 2005-11-16 Piolax Medical Devices, Inc. Cathéter d'infusion pour une solution de médicament
EP1682199A2 (fr) * 2003-11-15 2006-07-26 Medrad, Inc. Catheter pour imagerie diagnostique et procedures therapeutiques
US7939014B2 (en) * 2005-07-11 2011-05-10 Saint-Gobain Performance Plastics Corporation Radiation resistant silicone formulations and medical devices formed of same
US7943697B2 (en) * 2005-07-11 2011-05-17 Saint-Gobain Performance Plastics Corporation Radiation resistant silicone formulations and medical devices formed of same
WO2012068283A1 (fr) * 2010-11-16 2012-05-24 C2C Development, Llc Dispositifs ou procédés de cathéters à embout étanche
CN104039214A (zh) * 2011-11-30 2014-09-10 喉罩有限公司 内窥镜装置
WO2014113257A3 (fr) * 2013-01-15 2014-10-02 A.V. Medical Technologies, Ltd. Cathéter de perfusion équipé d'un système de robinet pour fil-guide
US8876754B2 (en) 2006-08-31 2014-11-04 Bayer Medical Care Inc. Catheter with filtering and sensing elements
US9133340B2 (en) 2005-07-11 2015-09-15 Saint-Gobain Performance Plastics Corporation Radiation resistant silicone formulations and medical devices formed of same
CN105107077A (zh) * 2015-09-15 2015-12-02 仇汉诚 一种微导管
CN105126231A (zh) * 2015-09-15 2015-12-09 仇汉诚 一种球囊导管
EP3061485A1 (fr) * 2015-02-25 2016-08-31 Innovations for Heart and Vessels Sp. z o.o. Cathéter intravasculaire pour diagnostics invasifs de vaisseaux périphériques
US10155099B2 (en) 2009-09-21 2018-12-18 Cook Regentec Llc Method for infusing stem cells
US10231857B2 (en) 2014-11-18 2019-03-19 A.V. Medical Technologies LTD Treating endoleakages in aortic aneurysm repairs
US10532193B2 (en) 2012-06-05 2020-01-14 Muffin Incorporated Catheter systems and methods useful for cell therapy
US10532185B2 (en) 2015-09-08 2020-01-14 Covidien Lp Navigable catheter distal tip configuration
US10561827B2 (en) 2012-07-09 2020-02-18 A V Medical Technologies, Ltd. Disrupting fibrin sheath from a host blood vessel and visualization thereof
US10617850B2 (en) 2015-06-25 2020-04-14 Covidien Lp Balloon catheter with fortified proximal outlet port, and manufacturing thereof
US11116948B2 (en) 2014-01-08 2021-09-14 A.V. Medical Technologies, Ltd Devices and methods for imaging and treating blood vessels

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5628527B2 (ja) * 2010-01-20 2014-11-19 オリンパス株式会社 カテーテルおよびカテーテル挿入器具
JP5995806B2 (ja) * 2013-08-13 2016-09-21 株式会社カテラ 側孔付き導入補助器具
JP2021058572A (ja) * 2019-10-08 2021-04-15 国立大学法人京都大学 カテーテル

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4023559A (en) * 1975-01-28 1977-05-17 Smith & Nephew (Australia) Pty. Limited Sampling catheter device
WO1989001352A1 (fr) * 1987-08-07 1989-02-23 Target Therapeutics Catheter a valve, et procede
US5035705A (en) * 1989-01-13 1991-07-30 Scimed Life Systems, Inc. Method of purging a balloon catheter
US5085635A (en) * 1990-05-18 1992-02-04 Cragg Andrew H Valved-tip angiographic catheter
WO1993025263A1 (fr) * 1992-06-05 1993-12-23 Cardiac Pathways Corporation Catheter a canule retractable pour l'administration de substances chimiques

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4023559A (en) * 1975-01-28 1977-05-17 Smith & Nephew (Australia) Pty. Limited Sampling catheter device
WO1989001352A1 (fr) * 1987-08-07 1989-02-23 Target Therapeutics Catheter a valve, et procede
US5035705A (en) * 1989-01-13 1991-07-30 Scimed Life Systems, Inc. Method of purging a balloon catheter
US5085635A (en) * 1990-05-18 1992-02-04 Cragg Andrew H Valved-tip angiographic catheter
WO1993025263A1 (fr) * 1992-06-05 1993-12-23 Cardiac Pathways Corporation Catheter a canule retractable pour l'administration de substances chimiques

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1000678C2 (en) * 1995-06-28 1996-12-31 Cordis Europ Catheter with hose-shaped basic body and distal end
EP0874653A1 (fr) * 1995-12-14 1998-11-04 Medtronic, Inc. Dispositif et procede pour administrer de maniere selective un fluide dans une lumiere anatomique
EP0874653A4 (fr) * 1995-12-14 1999-09-29 Medtronic Inc Dispositif et procede pour administrer de maniere selective un fluide dans une lumiere anatomique
EP0998321A4 (fr) * 1996-08-01 2000-05-10 Gerald S Linder Conduit d'intubation nasale et procede d'utilisation
EP0998321A1 (fr) * 1996-08-01 2000-05-10 Gerald S. Linder Conduit d'intubation nasale et procede d'utilisation
EP1682199A2 (fr) * 2003-11-15 2006-07-26 Medrad, Inc. Catheter pour imagerie diagnostique et procedures therapeutiques
EP1682199A4 (fr) * 2003-11-15 2008-03-12 Medrad Inc Catheter pour imagerie diagnostique et procedures therapeutiques
US8114047B2 (en) 2004-05-14 2012-02-14 Piolax Medical Devices, Inc. Drug solution infusion catheter
EP1595565A1 (fr) * 2004-05-14 2005-11-16 Piolax Medical Devices, Inc. Cathéter d'infusion pour une solution de médicament
US7939014B2 (en) * 2005-07-11 2011-05-10 Saint-Gobain Performance Plastics Corporation Radiation resistant silicone formulations and medical devices formed of same
US7943697B2 (en) * 2005-07-11 2011-05-17 Saint-Gobain Performance Plastics Corporation Radiation resistant silicone formulations and medical devices formed of same
US8129468B2 (en) 2005-07-11 2012-03-06 Saint-Gobain Performance Plastics Corporation Medical devices including a non-polar silicone matrix and a radiation resistant component
US9133340B2 (en) 2005-07-11 2015-09-15 Saint-Gobain Performance Plastics Corporation Radiation resistant silicone formulations and medical devices formed of same
US8876754B2 (en) 2006-08-31 2014-11-04 Bayer Medical Care Inc. Catheter with filtering and sensing elements
US10155099B2 (en) 2009-09-21 2018-12-18 Cook Regentec Llc Method for infusing stem cells
US20130310767A1 (en) * 2010-11-16 2013-11-21 C2C Developement, LLC Seal tip catheter devices or methods
WO2012068283A1 (fr) * 2010-11-16 2012-05-24 C2C Development, Llc Dispositifs ou procédés de cathéters à embout étanche
CN104039214A (zh) * 2011-11-30 2014-09-10 喉罩有限公司 内窥镜装置
US10532193B2 (en) 2012-06-05 2020-01-14 Muffin Incorporated Catheter systems and methods useful for cell therapy
US11413436B2 (en) 2012-07-09 2022-08-16 A V Medical Technologies Ltd. Disrupting fibrin sheath from a host blood vessel and visualization thereof
US10561827B2 (en) 2012-07-09 2020-02-18 A V Medical Technologies, Ltd. Disrupting fibrin sheath from a host blood vessel and visualization thereof
WO2014113257A3 (fr) * 2013-01-15 2014-10-02 A.V. Medical Technologies, Ltd. Cathéter de perfusion équipé d'un système de robinet pour fil-guide
US10363358B2 (en) 2013-01-15 2019-07-30 A.V. Medical Technologies Ltd. Infusion catheter with guidewire valving
US11052188B2 (en) 2013-01-15 2021-07-06 A.V. Medical Technologies LTD Double-lumen infusion catheter with infusion lumen widened along intermediate section thereof
US11116948B2 (en) 2014-01-08 2021-09-14 A.V. Medical Technologies, Ltd Devices and methods for imaging and treating blood vessels
US10231857B2 (en) 2014-11-18 2019-03-19 A.V. Medical Technologies LTD Treating endoleakages in aortic aneurysm repairs
EP3061485A1 (fr) * 2015-02-25 2016-08-31 Innovations for Heart and Vessels Sp. z o.o. Cathéter intravasculaire pour diagnostics invasifs de vaisseaux périphériques
US10617850B2 (en) 2015-06-25 2020-04-14 Covidien Lp Balloon catheter with fortified proximal outlet port, and manufacturing thereof
US10532185B2 (en) 2015-09-08 2020-01-14 Covidien Lp Navigable catheter distal tip configuration
CN105126231A (zh) * 2015-09-15 2015-12-09 仇汉诚 一种球囊导管
CN105107077A (zh) * 2015-09-15 2015-12-02 仇汉诚 一种微导管

Also Published As

Publication number Publication date
JPH09501597A (ja) 1997-02-18
EP0715529A1 (fr) 1996-06-12
GB9317539D0 (en) 1993-10-06

Similar Documents

Publication Publication Date Title
EP0715529A1 (fr) Catheter
US5741234A (en) Anatomical cavity access sealing condit
JP3349151B2 (ja) 内部マンドレルを有するカテーテルと使用方法
EP0630658B1 (fr) Hytérosalpingographie et salpingographie sélective
CA2334226C (fr) Localisation d'ouverture de tissus
US5558635A (en) Exchangeable guide system
US6071300A (en) Apparatus and method for percutaneous sealing of blood vessel punctures
US5234407A (en) Method and device for exchanging cardiovascular guide catheter while a previously inserted angioplasty guide wire remains in place
US5320639A (en) Vascular plug delivery system
US6423087B1 (en) Internal organ walls joining instrument for an endoscope
US6287322B1 (en) Tissue opening locator and everter and method
US5984950A (en) Percutaneous hemostasis device
US4844092A (en) Catheter Y-connector with guidewire locking means
US5910155A (en) Vascular wound closure system
US8382784B2 (en) Vessel cutting devices
EP0820784B1 (fr) Cathéter à ballon et méthode de son emploie
EP0955900B1 (fr) Systeme de fermeture de plaie vasculaire
US20010049534A1 (en) Device for inserting an aortic endoprosthesis
US20020123698A1 (en) Systems and methods for directing and snaring guidewires
JPH0575434B2 (fr)
US5330444A (en) Catheter tip with a low friction lining and method of use
JP2001527431A (ja) 血管創傷閉鎖装置
CN109498968B (zh) 一种导丝锚定球囊组件
US20080021383A1 (en) Angioplasty method and means for performing angioplasty
US20060020246A1 (en) Angiographic catheter for uterine artery embolization

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref country code: US

Ref document number: 1996 596266

Date of ref document: 19960208

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1994924917

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1994924917

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1994924917

Country of ref document: EP