WO1994028854A1 - Procede et dispositif permettant de traiter des tissus du corps - Google Patents

Procede et dispositif permettant de traiter des tissus du corps Download PDF

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Publication number
WO1994028854A1
WO1994028854A1 PCT/EP1994/001875 EP9401875W WO9428854A1 WO 1994028854 A1 WO1994028854 A1 WO 1994028854A1 EP 9401875 W EP9401875 W EP 9401875W WO 9428854 A1 WO9428854 A1 WO 9428854A1
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WO
WIPO (PCT)
Prior art keywords
liquid
tissue
substances
heat
therapeutically active
Prior art date
Application number
PCT/EP1994/001875
Other languages
German (de)
English (en)
Inventor
Peter KÖLTRINGER
Original Assignee
Koeltringer Peter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koeltringer Peter filed Critical Koeltringer Peter
Publication of WO1994028854A1 publication Critical patent/WO1994028854A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0261—Compresses or poultices for effecting heating or cooling medicated

Definitions

  • the present invention relates to a method for the treatment of body tissues by the use of liquid, optionally with the addition of (further) therapeutically active substances and / or heat, the treatment being carried out on a localized area of the patient's body , as well as a device for carrying out the method.
  • the present invention relates to a treatment method and a device for the treatment of body tissues with liquid and / or heat, liquid and heat being able to be used both together and, if appropriate, separately in time.
  • a particularly important and extensive area of application for such a method is the treatment of muscle tension which occurs, for example, in the area of the spine.
  • the causes are diverse and range from degenerative changes in the spinal column to inflammatory and traumatic changes to tension in the context of psychological disorders. Treatment of these complaints is possible on the one hand with medication, but the large number of side effects, particularly on the gastrointestinal tract, is particularly worth mentioning.
  • this group of medications which have an acological effect on the whole organism, there are also a whole range of physiotherapeutic treatments, which range from massages to special spinal exercises to bath therapy.
  • the object of the present invention is to provide treatment methods or treatment devices which require little expenditure of water, energy and amounts of extract, which do not require a large amount of space and which minimize the necessary hygiene measures, the treatment method and the Corresponding device can also be used for heart tendrils and venous diseases as well as for other contraindications in which the patient is not allowed to take a bath, whereby long-term treatments should preferably also be possible.
  • a treatment method and a treatment device should be created with which or with which one can achieve a similar effect in body tissues as in the treatment methods described at the outset, but with far less effort.
  • the present invention provides according to the method that, especially for long-term therapy, the liquid preferably evaporates or is introduced in a nebulized form in metered amounts into a mask covering the area to be treated or selected and by means of a temporarily or continuously operating heat source heat is generated in depth in the tissues present in this area, or that the therapeutically active substances with or without additional liquid into a heatable and, if necessary, coolable porous, which can be applied to the area and, if necessary, sealed on the back Material bodies are introduced in doses.
  • a device for the treatment of body tissues through the use of liquid, possibly with the addition of therapeutically active substances and possibly through the use of heat, which is provided by a liquid applicator with at least one outlet opening to the tissue to be treated and a deep heat generating source, which heats the tissue to be treated at the same time as the liquid application or at different times.
  • This treatment method or this device avoids the disadvantages mentioned when using the spa and, on the other hand, the heat achieves an additional effect which, for example, increased blood circulation, better skin permeability and thus also better absorption of substances by the skin.
  • the heat achieves an additional effect which, for example, increased blood circulation, better skin permeability and thus also better absorption of substances by the skin.
  • liquid is thus applied to the body tissue in small quantities and preferably this body tissue is simultaneously heated by a heat source or a support, such as e.g. a fleece is applied to a tissue area as a wound dressing with or without liquid or substance addition while heating.
  • a heat source or a support such as e.g. a fleece is applied to a tissue area as a wound dressing with or without liquid or substance addition while heating.
  • inhalation devices with a mask adapted to the face of the user and a heating device which causes a water bath with mucus-dissolving substances to evaporate are known, the user especially the moist, hot vapors should breathe in through the nose.
  • the device according to the present invention differs from the known inhalation device in several respects.
  • the liquid is used only in evaporated, hot form, while according to the invention the liquid is used in cold form when using a mask having a nebulizing space.
  • only known heating of the surface of the patient's face is achieved with the known inhalation devices.
  • a heat source which generates heat acting in depth, is used here just as little as a staggered supply of the liquid and the heat.
  • the liquid used can preferably consist of a basic solution such as water or physiological saline and additionally contain different extracts or medicaments to achieve certain effects such as increased circulation, muscle relaxation, anti-inflammatory effects, antibiotic effects and much more.
  • acetylsalicylic acid proteolytic enzymes
  • muscle relaxants e.g., spasticity releasing substances
  • electrolytes e.g. magnesium, antiplatelet drugs, antihypertensive drugs, antihypertensive drugs, vasodilator drugs, hair growth agents, salts (sea salt) and insulin either alone or in combination, for example antirheumatics with vitamin B cocomplexes or antirheumatics with muscle-relaxing medications.
  • the moisture released by the body in individual changes can also be taken into account as a liquid.
  • This enables targeted therapeutic use on tissues with little effort.
  • the invention makes it possible to combine cold and heat therapy in a simple manner, namely by occasionally switching on the heat source. This then alternately causes vascular toning and vaso-relaxing effects.
  • the radiant heat can thus only act on the tissue for a certain time and, independently of this, e.g. in the rest of the time the cold nebulized liquid achieve a cold effect.
  • a nebulizer When the liquid is administered by means of a nebulizer, this can preferably be done by an ultrasound source, which enables liquid administration or nebulization without simultaneous heating.
  • a dosing device In order to be able to administer an extract or a medicament in exact dosage in a simple manner, a dosing device is provided. In the present case, this is particularly important when it comes to the question of underdosing or overdosing.
  • the heat source preferably consists of an infrared or microwave radiation source. This can be achieved by increasing blood circulation in the areas to be heated, which in addition to circulatory disorders e.g. is also of great importance in healing processes after tissue injuries.
  • the device according to the invention has an opening for the liquid to the body tissue to be treated, which opening should be limited to this area as closely as possible, similar to a mask. As a side effect, the amount of liquid required is also limited.
  • a control unit is provided both for the heat and for the liquid, which enables predefined treatment times.
  • An alternative device for the treatment of body tissues by the use of liquid and / or therapeutically active substances is characterized in that the device arranges a porous for the liquid or the therapeutically active substance facing the tissue has heatable material layer, a heating device for heating the material layer or the underlying skin and / or the underlying tissue being provided.
  • a non-woven fabric is used as the porous, heatable material layer, e.g. also serve as a cover film providing the mask, which is glued to the treatment site via the fleece.
  • the mask or cover film can also extend over one or more body regions; what is essential is the best possible closure to the surroundings. This can also limit energy requirements.
  • With wound coverings there are also cases where a good external seal is neither necessary nor sensible, e.g. always the case when the liquid is not evaporated or atomized, but is only applied when heated. If heated wound dressings without added liquid are used, sealing is also not necessary. Particularly in the case of wound dressings which are brought to the tissue with heat, referred to here briefly as “heated wound dressings", it is possible to achieve a much faster healing due to the increased blood flow.
  • the present invention also provides a device for treating body tissues, which is characterized by a porous tissue area to be treated covering material layer and a device provided for heating and / or cooling the tissue area is marked.
  • a device for treating body tissues which is characterized by a porous tissue area to be treated covering material layer and a device provided for heating and / or cooling the tissue area is marked.
  • the application to a fleece-like tissue enables precise dosing of the administration amount even without a metering device, since the substance can be weighed in when the tissue is soaked. If the porous material layer of the invention is used as a "heated wound dressing", the advantage arises that, in addition to faster healing, there is also the possibility of being able to introduce a wide variety of substances better into the tissue under heat.
  • the invention therefore proposes a method according to which, on the one hand, the liquid, in small quantities, acts on the body tissue in a liquefied, nebulized or evaporated manner and, if necessary, is accompanied by specifically controllable heating of the tissue or the liquid by means of a heat source , on the other hand, only a pad is placed on a wound surface, which is left in place for a long time with heating.
  • FIG. 2 shows a schematic representation of a dosing cartridge which is suitable for use in the device similar to FIG. 1,
  • FIG. 3 shows a schematic diagram to explain the operation of the device of FIG. 1 in more detail
  • Fig. 4 shows an alternative device according to the invention for the treatment of body tissues with liquid and heat
  • FIG. 5 shows a schematic illustration of a further device according to the invention for treating wounds of a heatable pad.
  • the device according to the invention according to FIG. 1 has a mask 1, the open edge of which rests on the body tissue area to be treated, which is indicated only schematically by a dash-dotted line 2, the treatment being carried out primarily in the area covered by the mask shall be.
  • the edge of the mask 1 is preferably provided with a seal 3, by means of which the mist is prevented from escaping from the interior 17 of the mask 1, ie from the nebulization space.
  • a nebulizer 4 is provided, to which the liquid to be nebulized, in particular water, is supplied in a manner not shown.
  • the liquid is atomized via an ultrasound source which is arranged in the interior of the atomization device 4 and is fed via an electrical line 5.
  • the mist passes from the nebulization device 4 into the interior of the mask 1 via an outlet opening 6.
  • the nebulizing device 4 can itself contain a sufficient amount of the liquid to be nebulized, or the liquid can be fed from a supply source, in particular in the case of long-lasting treatments, via a line 15, which is shown in dashed lines in FIG. 1. If, as is preferably provided, an ultrasound source is used to atomize the liquid, the liquid is not or at least not warmed up to a significant extent by the atomization, so that a relatively cold mist is present in the mask.
  • an ultrasonic nebulizer there are also other systems for distributing the liquid in fine droplets or even in vapor form within the mask.
  • an electric pump similar to an air-free spray gun or by means of a corresponding connection for compressed air, could be used in the manner of a spray gun, i.e. that spraying, spraying and nebulizing devices known from other areas of technology can be used.
  • spraying, spraying and nebulizing devices known from other areas of technology can be used.
  • spraying, spraying and nebulizing devices known from other areas of technology can be used.
  • the evaporation of the corresponding liquid causes the same to be cooled, so that the desired cold treatment is achieved with little effort.
  • treatment with Liquid is only made with liquid in cold form. It is also entirely within the meaning of the invention if a warm liquid is used for the treatment instead of a cold liquid. In this case, the liquid must then be heated, for example by an electrical heating device (not shown), which can be accommodated in the atomizing device 4, for example. However, it is also possible to arrange such a heating device far from the mask and, for example, to warm up the liquid supplied via line 15 before this liquid enters the nebulizing device.
  • the nebulizing device 4 also contains a dosing device 7 for adding a medically effective extract additive to the mist.
  • This extract additive is under overpressure in a metering cartridge 8, the wall of which is opened by introducing the metering cartridge 8 into the metering device 7 without additional measures, so that the underpressure content of the metering cartridge gets into the nebulizing device 4 and there with the mist mixed.
  • a metering device of this type is known, for example, in the field of the manufacture of carbonated beverages, where a metering cartridge designed as a gas bottle containing CO 2 is screwed onto a mixing bottle, as a result of which a beveled cannula in the neck area of the mixing bottle is one that is present at the narrower end of the gas cartridge.
  • the membrane pierces and thereby allows the contents of the cartridge, which are under pressure, to flow into the mixing bottle.
  • this dosing cartridge 8 provides an exact dosage of the extract additive according to the content of this Cartridge sure.
  • a metering cartridge which is under excess pressure, can also be used to introduce the liquid into the nebulizing device 4.
  • the pressure of the cartridge can also be sufficient to introduce the contents of the dosing cartridge into the mask over the treatment period.
  • the dosing cartridge 8 can also be arranged far from the mask and can communicate with the nebulization device 4 via a line (not shown). As a result, the weight of the mask with attached elements can be reduced, which is advantageous for the convenience of the patient.
  • a heat source 9 which is formed by an infrared or microwave radiation source and which is fed in via an electrical line 10.
  • the heat source provides deep heat, i.e. not only heating the surface of the patient's skin, but also heating the underlying tissue.
  • a watertight, but radiation-permeable separating element 11 is expediently provided, by means of which the mist is prevented from reaching the radiation source 9, which could cause malfunctions in this radiation source.
  • the excess liquid which forms in the interior of the mask 1 is discharged through a drain or drip opening 12, for example, into a vessel (not shown) arranged underneath.
  • the electrical lines 5, 10 are connected to a time switch device 13, which in turn can be controlled via an electrical signal line 14.
  • the signal line 14 can for example be connected to a computer (not shown).
  • the time switch device can be formed by a computer, ie a separate time switch device is then not absolutely necessary.
  • the electrical supply to the time switch device 13 and the components 9 or 4 controlled thereby is preferably carried out via the lines 16.
  • the time switch device 13 can also be designed such that it can treat the treatment or a number of different treatments in accordance with one or can run several previously defined program.
  • This time switching device not only enables the total treatment time to be set, but also a separate setting of the treatment time by means of the nebulization device 4 and by means of the heat source 9, these devices also being able to work in a time-different manner, for example alternately or with different test conditions.
  • This device can also be used, for example, for skin diseases where something is to be vaporized under heat on a certain area, for example the device according to the invention can be used promisingly in the treatment of acne.
  • the admixture of local anesthetics for nerve pain or of antibiotics, antimycotics (fungus treatment substances) or anti-pyretics (anti-inflammatories) are also possible here, like many others.
  • the extract additive is mixed with the liquid for the nebulizing device 4 at an earlier point in time. If this liquid is fed to the line 15, a corresponding metering device can be arranged away from the mask.
  • the therapeutically active substances do not necessarily have to be introduced into the mask with the liquid, but can also be introduced into the mask separately from the liquid and only mix there with the liquid or reach the patient's skin in the area to be treated.
  • FIG. 2 shows the dosing cartridge 8 after its introduction into a screw sleeve 20.
  • the dosing cartridge 8 is inserted into the screw sleeve 20 in accordance with the arrow 21.
  • the screw sleeve 20 has at its right end 21 in FIG. 2 an internal thread 22, which together with an external thread 23 on a connecting piece 24 a receiving chamber 25 can be screwed.
  • the connector 24 has an annular chamber 26 which is dimensioned such that it receives the neck portion 27 of the metering cartridge 8.
  • An annular seal 28 within the connection piece 24 provides a seal between the neck part 27 of the metering cartridge and the connector 24.
  • Axially offset within the ring chamber 26 is a cannula 29 with a beveled membrane 30 at the end of the neck part 27 of the metering cartridge 8 facing end 31.
  • the cannula When screwing the screw sleeve 20 with the connection 24, the cannula pierces through the membrane, so that the contents of the metering cartridge due to the excess pressure prevailing inside the cartridge, which can be generated by a compressed gas or by steam pressure, through the longitudinal channel 32 of the cannula in the receiving chamber 25 flows into it.
  • the cannula can be provided with a one-way valve (not shown) so that backflow from the chamber 25 is excluded.
  • a further connecting part 35 designed as a needle valve seat is provided, with a valve needle 36 cooperating with the conical valve seat.
  • the valve needle 36 is pressed against the valve seat by a spring 38, the spring 38 being accommodated in a hat-like abutment 39 which has an outlet opening 40 for the therapeutically active substance.
  • an electromagnet 41 which, when excited via the electronic lines, not shown, the valve needle 36 pulls away from the valve seat 37 against the force of the compression spring 38 and thereby a part of the therapeutically active substance contained in the receiving chamber 25 can escape, this substance being able to pass through the valve needle and out of the outlet opening 40 in the abutment 39 enters the interior of the mask 1.
  • the amount of the therapeutically active substance determined by the content of the metering cartridge, divided into several partial doses, can be introduced into the mask over a relatively long period of time.
  • the cycle length can be adapted to the overpressure still present in the receiving chamber 25 in the course of the treatment.
  • the device according to FIG. 2 can be used at least in part for the implementation of the device of FIG. 1.
  • the arrangement to the left of the dashed line 43 can be used for the parts 8 and 7 of the device of FIG. 1, the chamber 25 then being to be regarded as belonging to the nebulization device 4 there.
  • FIG. 3 shows with a schematic control diagram how the time control 13 has three outputs in this example.
  • An outlet 50 leads to the liquid nebulizer, which is designed, for example, according to FIG. 1.
  • An output 51 leads to the electromagnet 41 of the metering device according to FIG. 2 and an output 52 leads to the heat radiation source 9, which can be designed according to FIG. 1.
  • the liquid applicator 4 and the metering device (FIG. 2) for the therapeutically active substances can be carried out independently of one another simultaneously or selected synchronously with each other.
  • the schematic control diagram for the device of FIG. 1 would look similar, only the output 50 would be missing.
  • the control of the liquid applicator would also serve to control the metering of the therapeutically active substance (s) which is or will be admixed with the liquid.
  • FIG 4 shows an alternative device for the treatment of body tissue with the therapeutically active substances with the possibility of having them act on the patient's skin when heated.
  • a porous material in the manner of a sponge or a fleece 60 is provided, which is soaked with a predetermined amount of the therapeutically active substance, possibly in a carrier liquid. Since the material layer has only a limited absorption capacity, the volume of the material layer can also determine the dosage of the therapeutically active substance. That the porous material can be dimensioned according to the invention, taking into account the absorption capacity of the selected material, so that it absorbs a certain amount of treatment liquid with a therapeutically active substance.
  • the porous material layer is preferably in direct contact with the body tissue to be treated.
  • a heating device 61 above the porous material layer, which ensures the introduction of the required heat.
  • This heating device can be implemented in a wide variety of ways.
  • it can contain a resistance element 64 or be designed as an inductive heating element.
  • it can also be implemented as an infrared or microwave source or as an element with electrodes have which induce or generate heat in the material of the heating element and / or in the material layer itself.
  • the device of FIG. 4 is preferably also covered with a membrane 62 in the form of a sealing film, which preferably extends over its edge area 63 an adhesive layer (not shown) is glued to the patient's skin.
  • a cooling device can also be used in addition to the heating device. This can be achieved, for example, by guiding a coolant in a heat exchanger loop.
  • the part labeled 64 can be understood as the heat exchanger loop.
  • the heat exchanger loop 64 is supplied with a coolant from an external cooling source. If such a heat exchanger loop is used, this can also be used to introduce the required heat, for which purpose a heat transfer medium is passed through the loop from an external source. In this way, a warm / cold treatment can also be carried out.
  • the energy required can come from a battery supplied by the Patient is carried with him. If cooling operation is also desired in this type of implementation, the necessary cooling can be achieved by utilizing the pelletizing effect.
  • FIG. 5 shows an embodiment which is very similar to the embodiment of FIG. 4, but in which the film 62 is either missing as a whole or is only used to fix the porous, heatable wound dressing 60.
  • the film shown here with dashed lines, can have a plurality of larger openings 65, at least in the area covering the porous material, which enable free air exchange between the patient's skin and the surroundings. It would also be conceivable to implement the film with a larger number of smaller openings up to breathable pores.
  • the wound dressing 5 is mainly intended for the treatment of wounds by means of heat (possibly and / or cold), the wound dressing not primarily being impregnated with a therapeutically active substance, but it is also conceivable here to provide the porous material layer with a therapeutically active substance, for example with a disinfectant substance in the treatment of burns.
  • Such nerve cell or nerve fiber diseases include various indications, e.g .:
  • the investigations according to the invention show that the preparation is suitable for nerve cell and nerve fiber regeneration after injury, namely for nerve fibers of all qualities, i.e. for motor as well as sensitive and vegetative nerve fibers.
  • the present invention provides a remedy here by the fact that the new form of administration using heat in the above-mentioned diseases or injuries enables pain and / or regeneration of the affected nerve cells and fibers to be largely relieved.
  • the following examples relate to the use of a combination of alpha-lipoic acid (thioctic acid) as a substance and an overheating of the tissue.
  • Alpha lipoic acid is applied to the skin and surrounded by a heating system, for example according to FIG. 4, which warms the skin and thus expands the capillaries in the microcirculation of the skin. Furthermore, this warming also opens the pores and, in addition, the skin becomes more permeable to substances, which means that the applied substance can now be introduced better and much more intensively into the tissue to be treated.
  • the blood flow means that the speed of healing processes is often accelerated many times over.
  • Alpha-lipoic acid also called thioctic acid
  • thioctic acid is commercially available in tablets and ampoule form, the dosage for tablets being around 200 mg, for ampoules the dosage is in the order of 10 mg to 50 mg / ml.
  • the main indication areas are diabetic polyneuropathy and, in some countries, certain liver diseases.
  • Polyneuropathy syndromes are widespread and occur in a wide variety of underlying diseases. Sugar metabolism disorders come first, followed by alcoholism, drug side effects, inflammatory diseases, circulatory disorders and tumors. The symptoms of weight very often begin with nighttime burning sensations which lead to the patient no longer being able to lie still. If you then get up and walk around for a while or move your feet, these symptoms will improve again. This is why this phase of symptoms is also known as "Burning Feet Syndrome" or "Restless Legs Syndrome". As a result, there are often sensations and hypersensitivities in the skin, which are usually present first in the leg area, furthermore muscle weakness and paralysis can follow.
  • the substance alpha-lipoic acid was applied to the tissue (fleece) 60 of the device in FIG. 4 and applied under the heating part 61 to the particularly painful areas of the skin.
  • the heating section achieved an overheating of approx. 1.5 - 2 degrees Celsius, which was kept constant for a period of 5 hours.
  • the entire system - alpha-lipoic acid-impregnated tissue 60 and heating element 61 - was attached to the corresponding parts of the body by means of bandages and sealed as well as possible from the surroundings.
  • the tissue was impregnated with an aqueous solution containing 20 mg alpha-lipoic acid. After a few minutes, the pain decreased, which remains constant. After repeated use, there were indications that the symptoms improved overall, and not only during the period of substance administration.
  • Carpal tunnel syndromes are disorders in the area of an arm nerve (median nerve), which occurs in the wrist area through a constriction to the ball of the thumb. At this constriction, especially in middle and older age, compression symptoms occur again and again, which can lead to massive pain, to emotional disturbances up to muscle weakness in the area of the thumb ball.
  • the causes are diverse, ranging from traumatic damage to completely unexplained cases or hormonal disorders. It is interesting that women in the menopause are very often affected by this disease.
  • the substance alpha-lipoic acid was applied to the tissue (fleece 60) and applied to the wrist under heating element 61.
  • the tissue was soaked in a solution of 20 mg alpha lipoic acid.
  • the heating section achieved an overheating of approx. 1.5 - 2 degrees Celsius, which was kept constant for a period of 5 hours.
  • the whole system - Tissue 60 impregnated with alpha lipoic acid and heating part 61 - was attached to the wrist by means of bandages.
  • Example 5 nerve conduction velocity measurement:

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Abstract

L'invention concerne un procédé et un dispositif permettant de traiter des tissus du corps. Le dispositif comprend un applicateur de liquide qui délivre des volumes réduits d'un liquide (vaporisé, volatilisé, atomisé ou imprégné dans un autre matériau) sur un tissu (2) circonscrit. Un dispositif du type masque permet de diriger ledit liquide sur les tissus organiques à traiter et ainsi de réaliser une application orientée dans la bonne direction. Cette application du liquide est combinée avec une source de chaleur (9) qui peut chauffer le tissu traité. La durée de l'application du liquide et celle de l'effet de la chaleur peuvent être commandées au moyen d'une minuterie (13). Un dispositif de dosage (7) permet de délivrer la dose exacte de la substance (8) utilisée. Lorsqu'on utilise un matériau imprégné de liquide, le dosage exact s'effectue pendant l'imprégnation. Les principaux domaines d'application de ce procédé sont la relaxation musculaire, une meilleure irrigation sanguine de la peau, le nettoyage de la peau, la dilatation des pores de la peau pour procéder à une désinfection, l'introduction et l'application de médicaments dans des tissus ainsi que des traitements déterminés par chaud-froid.
PCT/EP1994/001875 1993-06-11 1994-06-08 Procede et dispositif permettant de traiter des tissus du corps WO1994028854A1 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
ATA1138/93 1993-06-11
AT113893 1993-06-11
AT158593 1993-08-06
ATA1585/93 1993-08-09
AT202993 1993-10-08
ATA2029/93 1993-10-11
AT210993 1993-10-19
ATA2109/93 1993-10-20

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE868057C (de) * 1949-11-10 1953-02-23 Andreas Manetstoetter Vorrichtung zur Heranfuehrung von Heilmitteln in gasfoermigem Zustand an therapeutisch zu behandelnde Stellen
US4331137A (en) * 1980-07-22 1982-05-25 Kiichiro Sarui Apparatus for treating athlete's foot
DE3425962A1 (de) * 1984-07-14 1986-01-16 Günter 7290 Freudenstadt Schmid Vorrichtung zum auflegen von feuchten heilmitteln
CH662740A5 (de) * 1983-11-10 1987-10-30 Innovadata Ag Einrichtung zur gesteuerten transdermalen zufuehrung von pharmazeutischen wirkstoffen.
EP0258521A1 (fr) * 1986-08-23 1988-03-09 Arno Walter Latzke Dispositif pour appliquer des agents par diffusion à travers la peau
WO1993007842A1 (fr) * 1991-10-15 1993-04-29 Cygnus Therapeutic Systems Amelioration par voie thermique de l'administration percutanee de medicaments

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE868057C (de) * 1949-11-10 1953-02-23 Andreas Manetstoetter Vorrichtung zur Heranfuehrung von Heilmitteln in gasfoermigem Zustand an therapeutisch zu behandelnde Stellen
US4331137A (en) * 1980-07-22 1982-05-25 Kiichiro Sarui Apparatus for treating athlete's foot
CH662740A5 (de) * 1983-11-10 1987-10-30 Innovadata Ag Einrichtung zur gesteuerten transdermalen zufuehrung von pharmazeutischen wirkstoffen.
DE3425962A1 (de) * 1984-07-14 1986-01-16 Günter 7290 Freudenstadt Schmid Vorrichtung zum auflegen von feuchten heilmitteln
EP0258521A1 (fr) * 1986-08-23 1988-03-09 Arno Walter Latzke Dispositif pour appliquer des agents par diffusion à travers la peau
WO1993007842A1 (fr) * 1991-10-15 1993-04-29 Cygnus Therapeutic Systems Amelioration par voie thermique de l'administration percutanee de medicaments

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