WO1994027436A1 - Conservateurs presentant une efficacite antimicrobienne amelioree - Google Patents

Conservateurs presentant une efficacite antimicrobienne amelioree Download PDF

Info

Publication number
WO1994027436A1
WO1994027436A1 PCT/US1994/005693 US9405693W WO9427436A1 WO 1994027436 A1 WO1994027436 A1 WO 1994027436A1 US 9405693 W US9405693 W US 9405693W WO 9427436 A1 WO9427436 A1 WO 9427436A1
Authority
WO
WIPO (PCT)
Prior art keywords
compound
quaternary ammonium
group
paraben
antimicrobial
Prior art date
Application number
PCT/US1994/005693
Other languages
English (en)
Inventor
Benedict T. Decicco
James Kevin Keeven
Original Assignee
Decicco Benedict T
James Kevin Keeven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decicco Benedict T, James Kevin Keeven filed Critical Decicco Benedict T
Publication of WO1994027436A1 publication Critical patent/WO1994027436A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/51—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/524—Preservatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures

Abstract

Conservateur comprenant un niveau non irritant d'un composé d'ammonium quaternaire, tel que chlorure de benzalkonium ou chlorure de cétylpyridinium et soit un parabène, un chélatant hydrophobe, soit un composé alcoolique. La combinaison des deux composés permet d'atteindre une efficacité de destruction synergique contre des bactéries de contrôle, des bactéries persistantes et des bactéries adaptées, ainsi que contre des levures et des moisissures. Ladite combinaison permet également d'améliorer la rapidité de destruction.
PCT/US1994/005693 1993-05-20 1994-05-20 Conservateurs presentant une efficacite antimicrobienne amelioree WO1994027436A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6447093A 1993-05-20 1993-05-20
US08/064,470 1993-05-20

Publications (1)

Publication Number Publication Date
WO1994027436A1 true WO1994027436A1 (fr) 1994-12-08

Family

ID=22056218

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/005693 WO1994027436A1 (fr) 1993-05-20 1994-05-20 Conservateurs presentant une efficacite antimicrobienne amelioree

Country Status (1)

Country Link
WO (1) WO1994027436A1 (fr)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757402A1 (fr) * 1996-12-24 1998-06-26 Oreal Systeme conservateur et son utilisation dans une composition cosmetique ou pharmaceutique
US5972358A (en) * 1998-01-20 1999-10-26 Ethicon, Inc. Low tack lotion, gels and creams
US5997893A (en) * 1998-01-20 1999-12-07 Ethicon, Inc. Alcohol based anti-microbial compositions with cosmetic appearance
US6022551A (en) * 1998-01-20 2000-02-08 Ethicon, Inc. Antimicrobial composition
EP1080715A2 (fr) * 1999-08-05 2001-03-07 Bode Chemie GmbH & Co. Combinaison de principes actifs et compositions pour le soin des pieds le contenant
US6248343B1 (en) 1998-01-20 2001-06-19 Ethicon, Inc. Therapeutic antimicrobial compositions
WO2002069710A1 (fr) * 2001-03-01 2002-09-12 Lonza, Inc. Melanges conservateurs contenant des composes ammomium quaternaires
WO2004000373A1 (fr) * 2002-06-22 2003-12-31 Ecolab Inc. Concentre aqueux pour la desinfection de surfaces
WO2005097960A1 (fr) * 2004-04-07 2005-10-20 Advanced Medical Optics, Inc. Chlorure de cetylpyridinium utilise en tant qu'agent antimicrobien dans des compositions ophtalmiques
WO2005112907A2 (fr) * 2004-05-14 2005-12-01 Lifetech Usa, Inc. Agents non toxiques permettant de detruire e. coli et d'autres micro-organismes posant des problemes
WO2009047584A1 (fr) * 2007-10-11 2009-04-16 Hatchtech Pty. Ltd. Compositions de combinaison et procédés d'utilisation de celles-ci pour lutter contre une infestation
WO2016098965A1 (fr) * 2014-12-15 2016-06-23 코오롱생명과학 주식회사 Composition antiseptique et son utilisation
CN106119028A (zh) * 2016-07-05 2016-11-16 吴俊娟 一种三黄芎参酒
WO2018083675A1 (fr) * 2016-11-07 2018-05-11 Jubilant Life Sciences Limited Compositions antimicrobiennes synergiques
CN110290703A (zh) * 2016-12-16 2019-09-27 弗特鲁斯控股有限责任公司 季胺制剂及其用途
EP3496540A4 (fr) * 2016-08-11 2020-07-15 Ecolab USA Inc. Interaction entre des composés quaternaires antimicrobiens et des tensioactifs anioniques
US11406103B2 (en) 2016-03-01 2022-08-09 Ecolab Usa Inc. Sanitizing rinse based on quat-anionic surfactant synergy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2694663A (en) * 1950-09-05 1954-11-16 California Research Corp Synergistic microbicidal compositions
US4474748A (en) * 1979-09-26 1984-10-02 Johnson & Johnson Medicaments potentiated with phenyl alkanols

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2694663A (en) * 1950-09-05 1954-11-16 California Research Corp Synergistic microbicidal compositions
US4474748A (en) * 1979-09-26 1984-10-02 Johnson & Johnson Medicaments potentiated with phenyl alkanols

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Volume 113, No. 10, issued 03 September 1990, MORITA et al., "Ophthalmic Solution Containing Benzalkonium Chloride, P-Hydrobenzoate Esters, and Chelating Agents", Abstract No. 113:84881a. *
CHEMICAL ABSTRACTS, Volume 76, No. 15, issued 10 April 1972, RICHARDS et al., "Phenylethanol Enhancement of Preservatives Used in Ophthalmic Preparations", Abstract No. 81660j. *
CHEMICAL ABSTRACTS, Volume 80, No. 13, issued 01 April 1974, RICHARDS et al., "Enhancement of Benzalkonium Chloride and Chlorhexidine Acetate Activity Against Pseudomonas Aeruginosa by Aromatic Alcohols", Abstract No. 66969f. *
WINDHOLZ et al., "The Merck Index", Published 1983, by MERCK & CO,, INC., (RAHWAY, N.J., U.S.A.), Tenth Edition, see pages 706 and 707, Abstract No. 4765. *

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757402A1 (fr) * 1996-12-24 1998-06-26 Oreal Systeme conservateur et son utilisation dans une composition cosmetique ou pharmaceutique
EP0850634A1 (fr) * 1996-12-24 1998-07-01 L'oreal Système conservateur et son utilisation dans une composition cosmétique ou pharmaceutique
US6063388A (en) * 1996-12-24 2000-05-16 L'oreal Preserving system and its use in a cosmetic or pharmaceutical composition
US5972358A (en) * 1998-01-20 1999-10-26 Ethicon, Inc. Low tack lotion, gels and creams
US5997893A (en) * 1998-01-20 1999-12-07 Ethicon, Inc. Alcohol based anti-microbial compositions with cosmetic appearance
US6022551A (en) * 1998-01-20 2000-02-08 Ethicon, Inc. Antimicrobial composition
US6080416A (en) * 1998-01-20 2000-06-27 Ethicon, Inc. Low tack lotion, gels and creams
US6248343B1 (en) 1998-01-20 2001-06-19 Ethicon, Inc. Therapeutic antimicrobial compositions
EP1080715A2 (fr) * 1999-08-05 2001-03-07 Bode Chemie GmbH & Co. Combinaison de principes actifs et compositions pour le soin des pieds le contenant
EP1080715A3 (fr) * 1999-08-05 2002-04-10 Bode Chemie GmbH & Co. Combinaison de principes actifs et compositions pour le soin des pieds le contenant
EP1769678A2 (fr) * 2001-03-01 2007-04-04 Lonza, Inc. Mélanges conservateurs contenant des composés d'ammonium quaternaire
WO2002069710A1 (fr) * 2001-03-01 2002-09-12 Lonza, Inc. Melanges conservateurs contenant des composes ammomium quaternaires
EP1769678A3 (fr) * 2001-03-01 2007-05-16 Lonza, Inc. Mélanges conservateurs contenant des composés d'ammonium quaternaire
US7342044B2 (en) 2001-03-01 2008-03-11 Lonza Inc. Preservative blends containing quaternary ammonium compounds
WO2004000373A1 (fr) * 2002-06-22 2003-12-31 Ecolab Inc. Concentre aqueux pour la desinfection de surfaces
US7160846B2 (en) 2002-06-22 2007-01-09 Ecolab Inc. Aqueous concentrate for the disinfection of surfaces
ES2323827A1 (es) * 2004-04-07 2009-07-24 Advanced Medical Optics, Inc. Cloruro de cetilpiridinio como agente antimicrobiano en composiciones oftalmicas.
WO2005097960A1 (fr) * 2004-04-07 2005-10-20 Advanced Medical Optics, Inc. Chlorure de cetylpyridinium utilise en tant qu'agent antimicrobien dans des compositions ophtalmiques
CN1942571B (zh) * 2004-04-07 2012-02-15 雅培医疗光学公司 氯化十六烷基吡啶鎓在眼药组合物中作为抗菌剂
US7578996B2 (en) 2004-04-07 2009-08-25 Advanced Medical Optics, Inc. Cetylpyridinium chloride as an antimicrobial agent in ophthalmic compositions
US8268337B2 (en) 2004-05-14 2012-09-18 Wheeler Jack A Nontoxic killer of E. coli and other problem microorganisms
WO2005112907A3 (fr) * 2004-05-14 2006-04-13 Lifetech Usa Inc Agents non toxiques permettant de detruire e. coli et d'autres micro-organismes posant des problemes
WO2005112907A2 (fr) * 2004-05-14 2005-12-01 Lifetech Usa, Inc. Agents non toxiques permettant de detruire e. coli et d'autres micro-organismes posant des problemes
WO2009047584A1 (fr) * 2007-10-11 2009-04-16 Hatchtech Pty. Ltd. Compositions de combinaison et procédés d'utilisation de celles-ci pour lutter contre une infestation
WO2016098965A1 (fr) * 2014-12-15 2016-06-23 코오롱생명과학 주식회사 Composition antiseptique et son utilisation
US11406103B2 (en) 2016-03-01 2022-08-09 Ecolab Usa Inc. Sanitizing rinse based on quat-anionic surfactant synergy
CN106119028A (zh) * 2016-07-05 2016-11-16 吴俊娟 一种三黄芎参酒
US11044907B2 (en) 2016-08-11 2021-06-29 Ecolab Usa Inc. Interaction between antimicrobial quaternary compounds and anionic surfactants
US11839209B2 (en) 2016-08-11 2023-12-12 Ecolab Usa Inc. Interaction between antimicrobial quaternary compounds and anionic surfactants
EP3496540A4 (fr) * 2016-08-11 2020-07-15 Ecolab USA Inc. Interaction entre des composés quaternaires antimicrobiens et des tensioactifs anioniques
CN110113942A (zh) * 2016-11-07 2019-08-09 朱比兰特生命科学有限公司 协同抗微生物组合物
WO2018083675A1 (fr) * 2016-11-07 2018-05-11 Jubilant Life Sciences Limited Compositions antimicrobiennes synergiques
EP3554233A4 (fr) * 2016-12-16 2020-07-22 Vertellus Holdings LLC Formulations d'amine quaternaire et leurs utilisations
CN110290703A (zh) * 2016-12-16 2019-09-27 弗特鲁斯控股有限责任公司 季胺制剂及其用途
US11825842B2 (en) 2016-12-16 2023-11-28 Aurorium Holdings Llc Quaternary amine formulations and uses thereof

Similar Documents

Publication Publication Date Title
WO1994027436A1 (fr) Conservateurs presentant une efficacite antimicrobienne amelioree
US4836986A (en) Disinfecting and preserving systems and methods of use
US4758595A (en) Disinfecting and preserving systems and methods of use
JP2554237B2 (ja) コンタクトレンズの消毒保存用溶液
JP4856392B2 (ja) 防腐剤及びこれを含有する水性組成物
CA1236752A (fr) Composes et methode de desinfection
TWI498122B (zh) 含有硼酸鹽－多元醇複合物之水性藥學組成物
KR101738502B1 (ko) 보레이트-폴리올 복합체를 함유하는 수성 약학 조성물
KR20060135006A (ko) 아연 보존제 조성물 및 사용 방법
CN101678140A (zh) 用于隐形眼镜护理和防腐的药用组合物的磷脂组合物
CA2663817A1 (fr) Compositions pharmaceutiques aqueuses a conservation spontanee
EP0053451A2 (fr) Solution(polymérique) pour la désinfection et la conservation de lentilles de contact
WO2008052031A2 (fr) Dérivés de 2-pyrrolidone pour la conservation des compositions ophtalmiques, auriculaires et nasales
US4421665A (en) Contact lens cleaning composition containing lipid solvent and method of using
JP3407654B2 (ja) 眼科用組成物
JP4725699B2 (ja) 眼科用組成物及び眼科用組成物配合用防腐剤
JPH08133911A (ja) 抗菌組成物
WO2007088783A1 (fr) Collyre pour porteurs de verres de contact souples
JP2002316926A (ja) コンタクトレンズ用眼科用組成物及び眼刺激性の緩和方法
WO2005123148A1 (fr) Composition pour lentille de contact
NZ229706A (en) Ophthalmic solution containing dodecyl-dimethyl-(2-phenoxyethyl)-ammonium bromide as an antimicrobial agent; use in cleaning, disinfecting and conditioning contact lenses
JP5713034B2 (ja) 眼科用組成物、及び眼科製剤用防腐組成物
JP5584336B2 (ja) 防腐剤及びこれを含有する水性組成物
JP2003300871A (ja) 眼科用組成物
MXPA99005481A (en) Use of low molecular weight amino alcohols in ophthalmic compositions

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA JP

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA