WO1994011512A3 - Proteines et peptides allergenes provenant du pollen du cedre du japon - Google Patents

Proteines et peptides allergenes provenant du pollen du cedre du japon Download PDF

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Publication number
WO1994011512A3
WO1994011512A3 PCT/US1993/011000 US9311000W WO9411512A3 WO 1994011512 A3 WO1994011512 A3 WO 1994011512A3 US 9311000 W US9311000 W US 9311000W WO 9411512 A3 WO9411512 A3 WO 9411512A3
Authority
WO
WIPO (PCT)
Prior art keywords
cry
fragments
japanese cedar
peptides
cedar pollen
Prior art date
Application number
PCT/US1993/011000
Other languages
English (en)
Other versions
WO1994011512A9 (fr
WO1994011512A2 (fr
Inventor
Mei-Chang Kuo
Siu-Mei Helena Yeung
Andrew W Brauer
Joanne Pollock
Original Assignee
Immulogic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharma Corp filed Critical Immulogic Pharma Corp
Priority to JP6512408A priority Critical patent/JPH08505284A/ja
Priority to AU56681/94A priority patent/AU5668194A/en
Priority to EP94902242A priority patent/EP0669983A1/fr
Publication of WO1994011512A2 publication Critical patent/WO1994011512A2/fr
Publication of WO1994011512A3 publication Critical patent/WO1994011512A3/fr
Publication of WO1994011512A9 publication Critical patent/WO1994011512A9/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention se rapporte à des séquences d'acide nucléique codant pour l'allergène principal Cry j II du pollen du Cryptomeria japonica et à des fragments de celles-ci. La présente invention concerne également le Cry j II purifié et au moins un fragment de celui-ci obtenu dans une cellule hôte transformée par une séquence d'acide nucléique codant le Cry j II ou au moins un fragment de celle-ci et des fragments de Cry j préparés synthétiquement. Le Cry j II et les fragments de celui-ci sont utiles dans le diagnostic, le traitement et la prévention de la pollinose du cèdre du Japon
PCT/US1993/011000 1992-11-12 1993-11-12 Proteines et peptides allergenes provenant du pollen du cedre du japon WO1994011512A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP6512408A JPH08505284A (ja) 1992-11-12 1993-11-12 杉花粉由来のアレルゲン性蛋白質及びペプチド
AU56681/94A AU5668194A (en) 1992-11-12 1993-11-12 Allergenic proteins and peptides from japanese cedar pollen
EP94902242A EP0669983A1 (fr) 1992-11-12 1993-11-12 Proteines et peptides allergenes provenant du pollen du cedre du japon

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97517992A 1992-11-12 1992-11-12
US07/975,179 1992-11-12

Publications (3)

Publication Number Publication Date
WO1994011512A2 WO1994011512A2 (fr) 1994-05-26
WO1994011512A3 true WO1994011512A3 (fr) 1994-07-07
WO1994011512A9 WO1994011512A9 (fr) 1994-07-21

Family

ID=25522765

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/011000 WO1994011512A2 (fr) 1992-11-12 1993-11-12 Proteines et peptides allergenes provenant du pollen du cedre du japon

Country Status (6)

Country Link
EP (1) EP0669983A1 (fr)
JP (1) JPH08505284A (fr)
AU (1) AU5668194A (fr)
CA (1) CA2148713A1 (fr)
NZ (1) NZ258701A (fr)
WO (1) WO1994011512A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4176820B2 (ja) * 1993-11-05 2008-11-05 明治乳業株式会社 スギ花粉アレルゲンＣｒｙｊＩＩエピトープ
JP3649460B2 (ja) * 1993-11-05 2005-05-18 明治乳業株式会社 スギ花粉アレルゲンＣｒｙ ｊ ＩＩエピトープ
EP0655500B1 (fr) * 1993-11-05 1999-05-12 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Polypeptide alergénique provenant du pollen du cedre Japonais et DNA encodant celui-ci
US6759234B1 (en) 1994-09-02 2004-07-06 Immulogic Pharmaceutical Corporation Compositions and methods for administering to humans, peptides capable of down regulating an antigen specific immune response
JPH10505356A (ja) * 1994-09-02 1998-05-26 イミユロジク・フアーマシユーチカル・コーポレーシヨン ヒトへの投与のための組成物および方法、抗原特異的免疫応答のダウンレギュレーションを行うことが可能なペプチド
AU748104B2 (en) * 1994-09-02 2002-05-30 Merck Patent Gmbh Peptide compositions capable of down regulating an antigen specific immune response
TW438807B (en) * 1994-09-10 2001-06-07 Hayashibara Biochem Lab Novel peptides containing T-cell epitope(s) of cedar pollen allergens, the processes therefor and the pharmaceutical uses thereof
KR100487456B1 (ko) * 1996-03-10 2005-11-25 메이지 데어리즈 코포레이션 알레르기질환에대한펩티드면역치료제
ATE412175T1 (de) 1996-03-21 2008-11-15 Circassia Ltd Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz
US7112329B1 (en) 1996-06-14 2006-09-26 Meiji Milk Products Co. Ltd. T cell epitope peptide
JP4176750B2 (ja) * 1996-06-14 2008-11-05 明治乳業株式会社 Ｔ細胞エピトープペプチド
DE19957904A1 (de) * 1999-12-01 2001-06-07 Merck Patent Gmbh Insektengift-Allergene mit verminderter IgE-Reaktivität und Verfahren zu ihrer Herstellung
WO2011052697A1 (fr) 2009-10-30 2011-05-05 日本製紙株式会社 Protéine ayant une immunogénicité contre le pollen de cèdre, polynucléotide codant pour ladite protéine, et utilisations de ladite protéine et dudit polynucléotide
PL2861240T3 (pl) 2012-06-15 2021-07-05 Immunomic Therapeutics, Inc. Kwasy nukleinowe do leczenia alergii

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0416816A1 (fr) * 1989-09-02 1991-03-13 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Agent d'hyposensibilisation
WO1992003551A1 (fr) * 1990-08-13 1992-03-05 Biomay Biotechnik Produktions- Und Handelsgesellschaft M.B.H. Allergene p14 au pollen de bouleau servant au diagnostic et a la therapie des maladies allergiques

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0416816A1 (fr) * 1989-09-02 1991-03-13 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Agent d'hyposensibilisation
WO1992003551A1 (fr) * 1990-08-13 1992-03-05 Biomay Biotechnik Produktions- Und Handelsgesellschaft M.B.H. Allergene p14 au pollen de bouleau servant au diagnostic et a la therapie des maladies allergiques

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
M. SAKAGUCHI ET AL.;: "Identification of the second major allergen of Japanese cedar pollen", ALLERGY, vol. 45, 1990, pages 309 - 312 *
M. TANIAI ET AL.;: "N-terminal amino acid sequence of a major allergen of Japanese cedar pollen", FEBS LETTERS, vol. 239, 1988, pages 329 - 332 *

Also Published As

Publication number Publication date
EP0669983A1 (fr) 1995-09-06
AU5668194A (en) 1994-06-08
CA2148713A1 (fr) 1994-05-26
NZ258701A (en) 1996-11-26
JPH08505284A (ja) 1996-06-11
WO1994011512A2 (fr) 1994-05-26

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