WO1994004122A3 - Application de diacylglycerols pour accroitre la teneur en melanine des melanocytes - Google Patents

Application de diacylglycerols pour accroitre la teneur en melanine des melanocytes Download PDF

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Publication number
WO1994004122A3
WO1994004122A3 PCT/US1993/007853 US9307853W WO9404122A3 WO 1994004122 A3 WO1994004122 A3 WO 1994004122A3 US 9307853 W US9307853 W US 9307853W WO 9404122 A3 WO9404122 A3 WO 9404122A3
Authority
WO
WIPO (PCT)
Prior art keywords
melanocytes
increasing
melanin content
diacylglycerols
melanin
Prior art date
Application number
PCT/US1993/007853
Other languages
English (en)
Other versions
WO1994004122A2 (fr
Inventor
Barbara A Gilchrest
Philip R Gordon
Original Assignee
Univ Boston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Boston filed Critical Univ Boston
Priority to JP6506555A priority Critical patent/JPH08500595A/ja
Priority to DE69324689T priority patent/DE69324689D1/de
Priority to EP93920249A priority patent/EP0655907B1/fr
Publication of WO1994004122A2 publication Critical patent/WO1994004122A2/fr
Publication of WO1994004122A3 publication Critical patent/WO1994004122A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0626—Melanocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Procédé pour induire la synthèse de la mélanine dans les mélanocytes pour de ce fait augmenter leur teneur en mélanine et, ainsi, accroître la pigmentation, mélanocytes à teneur accrue en mélanine produits par ces procédés, et leurs applications.
PCT/US1993/007853 1992-08-21 1993-08-20 Application de diacylglycerols pour accroitre la teneur en melanine des melanocytes WO1994004122A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP6506555A JPH08500595A (ja) 1992-08-21 1993-08-20 メラニン細胞のメラニン含有量を増加させるためのジアシルグリセロールの使用
DE69324689T DE69324689D1 (de) 1992-08-21 1993-08-20 Verwendung von diacylglycerolen zur steigerung des melaningehaltes in melanozyten
EP93920249A EP0655907B1 (fr) 1992-08-21 1993-08-20 Application de diacylolycerols pour accroitre la teneur en melanine des melanocytes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/934,872 US5352440A (en) 1988-03-30 1992-08-21 Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof
US07/934,872 1992-08-21

Publications (2)

Publication Number Publication Date
WO1994004122A2 WO1994004122A2 (fr) 1994-03-03
WO1994004122A3 true WO1994004122A3 (fr) 1994-03-31

Family

ID=25466212

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/007853 WO1994004122A2 (fr) 1992-08-21 1993-08-20 Application de diacylglycerols pour accroitre la teneur en melanine des melanocytes

Country Status (6)

Country Link
US (2) US5352440A (fr)
EP (1) EP0655907B1 (fr)
JP (1) JPH08500595A (fr)
CA (1) CA2143003A1 (fr)
DE (1) DE69324689D1 (fr)
WO (1) WO1994004122A2 (fr)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352440A (en) * 1988-03-30 1994-10-04 Trustees Of Boston University Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof
US5700450A (en) * 1988-03-30 1997-12-23 The Trustees Of Boston University Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof
FR2706304B1 (fr) * 1993-06-15 1995-09-01 Carita Sa Utilisation des huiles de Chaulmoogra dans le domaine cosmétique et pharmaceutique, notamment en dermatologie, pour harmoniser la pigmentation de la peau.
SE9303444D0 (sv) * 1993-10-20 1993-10-20 Kabi Pharmacia Ab New use of prostaglandins
US5798386A (en) * 1994-08-03 1998-08-25 Cell Therapeutics, Inc. Angiogenic lipid formulations
US5955624A (en) * 1994-08-03 1999-09-21 Cell Therapeutics, Inc. Growth stimulating factors
US6808709B1 (en) * 1994-12-30 2004-10-26 The Regents Of The University Of California Immunoglobulins containing protection proteins and their use
AU722668B2 (en) 1994-12-30 2000-08-10 King's College London Methods for producing immunoglobulins containing protection proteins in plants and their use
US6046037A (en) * 1994-12-30 2000-04-04 Hiatt; Andrew C. Method for producing immunoglobulins containing protection proteins in plants and their use
KR980008211A (ko) * 1996-07-27 1998-04-30 유상옥 소목(Caesapinia sappan L.) 추출물을 함유하는 탠닝 화장료
WO1998055085A1 (fr) * 1997-06-04 1998-12-10 Codon Pharmaceuticals, Inc. Compositions pharmaceutiques et procedes
AU740783B2 (en) * 1996-09-18 2001-11-15 Applied Genetics Incorporated Dermatics Pharmaceutical compositions and methods
US6623724B2 (en) * 1996-09-18 2003-09-23 Applied Genetics Incorporated Dermatics Dermatological compositions and methods
US6214888B1 (en) * 1996-09-18 2001-04-10 Applied Genetics Incorporated Dermatological compounds
US6160021A (en) * 1997-02-04 2000-12-12 The General Hospital Corporation Method for treating epidermal or dermal conditions
KR100385448B1 (ko) * 1997-02-18 2003-08-19 주식회사 코리아나화장품 브라질린(Brazilin)을주성분으로함유하는탠닝화장료
US6267948B1 (en) 1998-04-06 2001-07-31 Applied Genetics Incorporated Dermatics Dermatological formulations and methods
AU4215499A (en) * 1998-05-28 2002-07-08 Codon Pharmaceuticals, Inc. Treatment of neurodegenerative diseases
AU2000238755A1 (en) * 2000-03-10 2001-09-24 Applied Genetics Incorporated Dermatics Dermatological compounds
US7951378B2 (en) * 2000-04-28 2011-05-31 Planet Biotechnology Inc. Immunoadhesin comprising a chimeric ICAM-1 molecule produced in a plant
US20060015969A1 (en) * 2000-04-28 2006-01-19 Planet Biotechnology, Inc. Novel immunoadhesins for treating and prventing toxicity and pathogen-mediated diseases
WO2003022043A1 (fr) * 2001-09-06 2003-03-20 Shiseido Company, Ltd. Systeme de reconstitution de follicule pileux et animal portant ce systeme
US20070118934A1 (en) * 2001-10-26 2007-05-24 Planet Biotechnology, Inc. Chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax
DE10160966A1 (de) * 2001-12-12 2003-06-26 Beiersdorf Ag Melaninbildendes Haarfärbungsprodukt
US7368131B2 (en) * 2003-02-27 2008-05-06 Supernatural Health, Inc. Method and composition for treating hypopigmentation of the hair and skin
WO2009064492A1 (fr) * 2007-11-14 2009-05-22 New York University School Of Medicine Composés de quinoline à titre de modificateurs de mélanogenèse et leurs utilisations
WO2009064493A1 (fr) * 2007-11-14 2009-05-22 New York University School Of Medicine Composés tricycliques en tant que modificateurs de la mélanogenèse et leurs utilisations
KR100924060B1 (ko) 2007-11-17 2009-10-27 바이오스펙트럼 주식회사 퓨린 유도체를 포함하는 멜라닌 생성 촉진 조성물
US20100040568A1 (en) * 2008-04-30 2010-02-18 Skinmedica, Inc. Steroidal compounds as melanogenesis modifiers and uses thereof
FR2951938B1 (fr) 2009-10-30 2012-01-06 Oreal Utilisation d'un extrait de punica granatum pour lutter contre la canitie
US8772252B2 (en) 2011-01-27 2014-07-08 New York University Coumarin compounds as melanogenesis modifiers and uses thereof
FR2978659B1 (fr) 2011-08-05 2014-01-10 Oreal Utilisation de composes cannabinoides pour stimuler la melanogenese
FR2999931A1 (fr) 2012-12-21 2014-06-27 Oreal Utilisation de microorganismes probiotiques comme agent favorisant la synthese de melanine
FR2999932B1 (fr) 2012-12-21 2020-01-31 Société des Produits Nestlé S.A. Utilisation de microorganismes probiotiques comme agent favorisant la synthese de melanine
CA3184332A1 (fr) 2020-06-26 2021-12-30 Artur Manuel Cavaco Paulo Composition pour la modulation de follicules pileux, procedes et utilisations associes
WO2022098908A1 (fr) * 2020-11-05 2022-05-12 The Regents Of The University Of Colorado, A Body Corporate Compositions et méthodes de traitement de l'homocystinurie et d'autres pathologies à l'aide de polyamines

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989009258A1 (fr) * 1988-03-30 1989-10-05 Trustees Of Tufts College Procedes d'augmentation de teneur en melanine et induisant la proliferation de melanocytes in vivo et in vitro
WO1991007168A1 (fr) * 1989-11-09 1991-05-30 Schering-Plough Healthcare Products, Inc. Riboflavine comme promoteur du tannage
WO1991007167A1 (fr) * 1989-11-09 1991-05-30 Schering-Plough Healthcare Products, Inc. Activateurs de la kinase de proteine comme promoteurs de la production de melamine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4443546A (en) * 1980-07-07 1984-04-17 The Beth Israel Hospital Association Process and composition for propagating mammalian cells
US4508706A (en) * 1983-03-30 1985-04-02 Yale University Composition for increasing melanin in mammalian skin and hair
US4618484A (en) * 1983-03-30 1986-10-21 Yale University Composition and method for treatment of melanomas
US4695449A (en) * 1983-03-30 1987-09-22 Yale University Composition and method for treatment of melanomas
NL8601767A (nl) * 1986-07-07 1988-02-01 Schreuder Chem Adviesbureau Huidbruiningsmiddel.
US4816450A (en) * 1986-09-15 1989-03-28 Duke University Inhibition of protein kinase C by long-chain bases
US5352440A (en) * 1988-03-30 1994-10-04 Trustees Of Boston University Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989009258A1 (fr) * 1988-03-30 1989-10-05 Trustees Of Tufts College Procedes d'augmentation de teneur en melanine et induisant la proliferation de melanocytes in vivo et in vitro
WO1991007168A1 (fr) * 1989-11-09 1991-05-30 Schering-Plough Healthcare Products, Inc. Riboflavine comme promoteur du tannage
WO1991007167A1 (fr) * 1989-11-09 1991-05-30 Schering-Plough Healthcare Products, Inc. Activateurs de la kinase de proteine comme promoteurs de la production de melamine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
P.R. GORDON & B. A. GILCHREST: "HUMAN MELANOGENESIS IS STIMULATED BY DIACYLGLYCEROL", THE JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 93, no. 5, November 1989 (1989-11-01), NEW YORK, pages 93 - 95, XP000562502, DOI: doi:10.1111/1523-1747.ep12319900 *

Also Published As

Publication number Publication date
US5750091A (en) 1998-05-12
US5352440A (en) 1994-10-04
WO1994004122A2 (fr) 1994-03-03
EP0655907A1 (fr) 1995-06-07
EP0655907B1 (fr) 1999-04-28
CA2143003A1 (fr) 1994-03-03
DE69324689D1 (de) 1999-06-02
JPH08500595A (ja) 1996-01-23

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