WO1994002586A3 - Repression of virulent gene expression - Google Patents

Repression of virulent gene expression Download PDF

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Publication number
WO1994002586A3
WO1994002586A3 PCT/GB1993/001541 GB9301541W WO9402586A3 WO 1994002586 A3 WO1994002586 A3 WO 1994002586A3 GB 9301541 W GB9301541 W GB 9301541W WO 9402586 A3 WO9402586 A3 WO 9402586A3
Authority
WO
WIPO (PCT)
Prior art keywords
repression
gene expression
food
virulence
virulent gene
Prior art date
Application number
PCT/GB1993/001541
Other languages
French (fr)
Other versions
WO1994002586A2 (en
Inventor
Simon Fearon Park
Original Assignee
Agricultural & Food Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricultural & Food Res filed Critical Agricultural & Food Res
Priority to AU47144/93A priority Critical patent/AU4714493A/en
Publication of WO1994002586A2 publication Critical patent/WO1994002586A2/en
Publication of WO1994002586A3 publication Critical patent/WO1994002586A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/097—Preservation
    • A23C19/10—Addition of preservatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
    • A23K30/10—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder
    • A23K30/15—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs of green fodder using chemicals or microorganisms for ensilaging
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3481—Organic compounds containing oxygen
    • A23L3/349—Organic compounds containing oxygen with singly-bound oxygen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3544—Organic compounds containing hetero rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3562—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Expression of a gene for virulence in a microorganism is repressed by exposing the microorganism to cellobiose or arbutin or combinations thereof. For example, the virulence of pathogenic strains of Listeria may be repressed in or on food by admixing cellobiose or arbutin or combinations thereof with the food. An assay is provided for a compound which suppresses virulence in food-contaminating bacteria, including Listeria.
PCT/GB1993/001541 1992-07-24 1993-07-22 Repression of virulent gene expression WO1994002586A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU47144/93A AU4714493A (en) 1992-07-24 1993-07-22 Repression of virulent gene expression

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929215768A GB9215768D0 (en) 1992-07-24 1992-07-24 Repression of virulent gene expression
GB9215768.4 1992-07-24

Publications (2)

Publication Number Publication Date
WO1994002586A2 WO1994002586A2 (en) 1994-02-03
WO1994002586A3 true WO1994002586A3 (en) 1994-03-17

Family

ID=10719246

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1993/001541 WO1994002586A2 (en) 1992-07-24 1993-07-22 Repression of virulent gene expression

Country Status (3)

Country Link
AU (1) AU4714493A (en)
GB (1) GB9215768D0 (en)
WO (1) WO1994002586A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6020121A (en) * 1995-09-29 2000-02-01 Microcide Pharmaceuticals, Inc. Inhibitors of regulatory pathways
DE10147100A1 (en) 2001-09-25 2003-04-17 Numico Res B V Anti-infective carbohydrates

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2070217A (en) * 1980-02-05 1981-09-03 House Food Industrial Co Method for producing dry fruit chips
EP0152852A2 (en) * 1984-02-03 1985-08-28 Josef Dr. PÜHRINGER Antimicrobial agent for treating buildings, building materials, textiles, leather, agricultural products and foodstuffs
JPS62267238A (en) * 1986-05-15 1987-11-19 R P Shiila- Kk Production of insulin suppository
FR2609397A1 (en) * 1988-02-23 1988-07-15 Serobiologiques Lab Sa Use of a substance or composition of carbohydrate nature as active principle of a dermatological and/or cosmetological and/or pharmaceutical and/or cell-stimulating composition, and composition containing such a substance or composition of carbohydrate nature
EP0275834A1 (en) * 1986-12-29 1988-07-27 Warner-Lambert Company Continuous process for producing a comestible tablet
JPS63199282A (en) * 1987-02-13 1988-08-17 Shiseido Co Ltd Antioxidant
WO1989004165A1 (en) * 1987-10-19 1989-05-18 Haklitch Joseph A Detoxifying food supplement
JPH01225457A (en) * 1988-03-04 1989-09-08 Ajinomoto Co Inc Raw material having low sweetness
US4879280A (en) * 1981-09-24 1989-11-07 Fresenius Ag Dialysis solution for use in intraperitoneal dialysis
JPH02207092A (en) * 1989-02-07 1990-08-16 Kirin Brewery Co Ltd Production of freeze-dried preparation of anthracycline compound or salt thereof
EP0415720A2 (en) * 1989-08-29 1991-03-06 Nihon Shokuhin Kako Co., Ltd. Beta-glucooligosaccharide-containing composition, and method of improving intestinal flora
JPH0352810A (en) * 1989-07-20 1991-03-07 T Knight Albert Substance passing through blood- brain barrier

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2070217A (en) * 1980-02-05 1981-09-03 House Food Industrial Co Method for producing dry fruit chips
US4879280A (en) * 1981-09-24 1989-11-07 Fresenius Ag Dialysis solution for use in intraperitoneal dialysis
EP0152852A2 (en) * 1984-02-03 1985-08-28 Josef Dr. PÜHRINGER Antimicrobial agent for treating buildings, building materials, textiles, leather, agricultural products and foodstuffs
JPS62267238A (en) * 1986-05-15 1987-11-19 R P Shiila- Kk Production of insulin suppository
EP0275834A1 (en) * 1986-12-29 1988-07-27 Warner-Lambert Company Continuous process for producing a comestible tablet
JPS63199282A (en) * 1987-02-13 1988-08-17 Shiseido Co Ltd Antioxidant
WO1989004165A1 (en) * 1987-10-19 1989-05-18 Haklitch Joseph A Detoxifying food supplement
FR2609397A1 (en) * 1988-02-23 1988-07-15 Serobiologiques Lab Sa Use of a substance or composition of carbohydrate nature as active principle of a dermatological and/or cosmetological and/or pharmaceutical and/or cell-stimulating composition, and composition containing such a substance or composition of carbohydrate nature
JPH01225457A (en) * 1988-03-04 1989-09-08 Ajinomoto Co Inc Raw material having low sweetness
JPH02207092A (en) * 1989-02-07 1990-08-16 Kirin Brewery Co Ltd Production of freeze-dried preparation of anthracycline compound or salt thereof
JPH0352810A (en) * 1989-07-20 1991-03-07 T Knight Albert Substance passing through blood- brain barrier
EP0415720A2 (en) * 1989-08-29 1991-03-06 Nihon Shokuhin Kako Co., Ltd. Beta-glucooligosaccharide-containing composition, and method of improving intestinal flora

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 103, no. 8, 26 August 1985, Columbus, Ohio, US; abstract no. 59328 *
CHEMICAL ABSTRACTS, vol. 110, no. 8, 20 February 1989, Columbus, Ohio, US; abstract no. 63726 *
CHEMICAL ABSTRACTS, vol. 112, no. 13, 26 March 1990, Columbus, Ohio, US; abstract no. 117622 *
CHEMICAL ABSTRACTS, vol. 114, no. 20, 20 May 1991, Columbus, Ohio, US; abstract no. 192601 *
CHEMICAL ABSTRACTS, vol. 115, no. 20, 18 November 1991, Columbus, Ohio, US; abstract no. 214851 *
D.A.SCHIEMANN: "COMPARISON OF ENRICHMENT...", JOURNAL OF FOOD PROTECTION, vol. 46, no. 11, November 1983 (1983-11-01), pages 957 - 964 *
G.A.CANGELOSI ET AL.: "SUGARS INDUCE THE AGROBACTERIUM VIRULENCE GENES...", PROC.NATL.ACAD.SCI.USA, vol. 87, no. 17, September 1990 (1990-09-01), pages 6708 - 6711 *
M.M.OMAR: "PHENOLIC COMPOUNDS...", ABSTR.PAP.AM.CHEM.SOC., vol. 202, no. 1-2, 1991 *
PATENT ABSTRACTS OF JAPAN vol. 12, no. 482 (C - 553)<3329> 15 December 1988 (1988-12-15) *
S.F.PARK ET AL.: "EXPRESSION OF LISTERIOLYSIN...", MOL.MICROBIOL., vol. 8, no. 4, May 1993 (1993-05-01), pages 653 - 661 *
W.WEUFFEN ET AL.: "ZUSAMMENHÄNGE ZWISCHEN...", PHARMAZIE, vol. 25, 1970, pages 480 - 484 *
Y.-Y. MO ET AL.: "PLANT SIGNAL MOLECULES ACTIVATE THE SYRB GENE...", J.BACTERIOL., vol. 173, no. 18, September 1991 (1991-09-01), pages 5784 - 5792 *

Also Published As

Publication number Publication date
AU4714493A (en) 1994-02-14
WO1994002586A2 (en) 1994-02-03
GB9215768D0 (en) 1992-09-09

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