WO1993015784A1 - Procede d'etirage d'une solution - Google Patents

Procede d'etirage d'une solution Download PDF

Info

Publication number
WO1993015784A1
WO1993015784A1 PCT/US1993/001303 US9301303W WO9315784A1 WO 1993015784 A1 WO1993015784 A1 WO 1993015784A1 US 9301303 W US9301303 W US 9301303W WO 9315784 A1 WO9315784 A1 WO 9315784A1
Authority
WO
WIPO (PCT)
Prior art keywords
encapsulating material
range
material solids
solvent
solution
Prior art date
Application number
PCT/US1993/001303
Other languages
English (en)
Inventor
Gregg S. Sutton
Kenneth D. Dotzenroth
Original Assignee
Navarre Biomedical, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Navarre Biomedical, Ltd. filed Critical Navarre Biomedical, Ltd.
Publication of WO1993015784A1 publication Critical patent/WO1993015784A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A61M25/0012—Making of catheters or other medical or surgical tubes with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00—Processes for applying liquids or other fluent materials
    • B05D1/18—Processes for applying liquids or other fluent materials performed by dipping
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
    • B05D7/20—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to wires
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/14—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of indefinite length
    • B29C39/18—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of indefinite length incorporating preformed parts or layers, e.g. casting around inserts or for coating articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/22—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of indefinite length
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
    • B29C70/04—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts comprising reinforcements only, e.g. self-reinforcing plastics
    • B29C70/06—Fibrous reinforcements only
    • B29C70/10—Fibrous reinforcements only characterised by the structure of fibrous reinforcements, e.g. hollow fibres
    • B29C70/16—Fibrous reinforcements only characterised by the structure of fibrous reinforcements, e.g. hollow fibres using fibres of substantial or continuous length
    • B29C70/20—Fibrous reinforcements only characterised by the structure of fibrous reinforcements, e.g. hollow fibres using fibres of substantial or continuous length oriented in a single direction, e.g. roofing or other parallel fibres
    • B29C70/205—Fibrous reinforcements only characterised by the structure of fibrous reinforcements, e.g. hollow fibres using fibres of substantial or continuous length oriented in a single direction, e.g. roofing or other parallel fibres the structure being shaped to form a three-dimensional configuration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7542—Catheters

Definitions

  • This invention relates to a method of constructing thin film tubes and more particularly a tube for use in an encapsulated reinforcing coil kink resistant tube.
  • BACKGROUND OF THE INVENTION Kink resistant tubing finds application as a material to construct medical catheters for infants, children and adults.
  • the main application of catheters is for central venous access.
  • Central venous access can be used for the administration of drugs, fluids or the monitoring of pressures.
  • Administration of drugs implies the use of intravenous fluids, continuous drips or boluses of drugs.
  • the first route of central access in a neonate is an umbilical artery catheter or venous catheter. Catheters are placed into umbilical artery or vein, in the remaining stump of the umbilical cord in the infant.
  • Such a catheter can be used for monitoring blood pressure, central venous pressure, administering life sustaining drugs, or delivering IV fluids.
  • Other routes of catheterization include the wrist or a radial artery. Usually drugs are not given by this route. In older children, after the neonatal period, the femoral artery and vein can be used, or the right internal jugular veins. Another route less commonly used in children, but nonetheless very useful for treating adults and teenagers, is the subclavian vein for central monitoring.
  • these catheters may also be employed in a procedure known as cardiac catheterization. This is a procedure by which pressures of the heart can be monitored as well as blood withdrawal from the catheter to measure oxygen tension and Ph in the chambers of the heart. Oxygen tension is the oxygen saturation and the partial pressure of oxygen in blood samples in the various chambers of the heart.
  • cardiac catheterization This is a procedure by which pressures of the heart can be monitored as well as blood withdrawal from the catheter to measure oxygen tension and Ph in the chambers of the heart.
  • Oxygen tension is the oxygen saturation and the partial pressure of oxygen in blood samples in the various chambers of the heart.
  • These catheters can be advanced into the heart through either a femoral route, which is the most common router, or through a vein in the arm known as the brachiocephalic.
  • catheters placed in arteries or central veins are convenient routes for blood withdrawal.
  • Prior art catheters for central venous access and cardiac catheterization consist of tubes made of a plastic tubing of a pliable plastic.
  • the plastics come in different types that have various degrees of pliability depending upon the temperature. These catheters are usually fairly stiff at room temperature but become very soft as they are exposed to body temperature.
  • Plastic catheters of the prior art have many disadvantages. As noted above, they are fabricated from plastics which often soften when inserted into a body. As a result, such catheters become more difficult to manipulate. Such prior art catheters have a tendency to kink and buckle when they become pliable while implanted in blood vessels. The mechanism of failure includes kinking which may occur, for example, when the catheter butts up against the wall of a vessel. Such catheters may also kink by folding back on itself while being advanced into a vessel. When a catheter kinks it is no longer able to transport drugs or IV fluids into the vessel. Kinking also effects the withdrawal of backblood from the catheter.
  • Methods of remedying an obstructed catheter can consist of flushing the catheter with a bit of high pressure fluid to try to remove the kink. If the kinking is severe enough, the catheter must be removed and replaced with a new one. Unfortunately, life- threatening conditions can occur from a kinked catheter, as, for example, in the event that the obstruction of flow of a life sustaining drug to the patient is obstructed by kinking.
  • Long-term catheters such as the Hickman and Broviac catheters are implantable catheters that are implanted under the skin into central veins, usually through a subclavian route or an internal jugular route, and occasionally through a femoral route. These catheters are also implanted in an area near the neck where they can be kept clean. These catheters are implanted on a permanent basis. They are usually used for patients with chronic illnesses, such as, for example, in the case of children who receive chemotherapy.
  • Catheters can be placed for temporary and permanent use in jugular and subclavian vessels. Catheters can also be made for use in cardiac catheterization. Small bore catheters such as those provided by the instant invention enjoy a distinct advantage over larger bore catheters because they can form certain shapes for use in areas such as cardiac coronary catheterization.
  • a solution draw thin walled construction method for making a kink resistant tubing out of a solution of a solvent system.
  • the thin walled tube construction method of the invention starts by creating a solution of a predetermined thin walled polymer out of the mixing of solids and a solvent. The resulting solution is then used in a vessel that contains a hole in it.
  • a small layer of solution is then deposited a thin layer of encapsulating material on a mandrel creating a thin walled tube by solvent evaporation.
  • a reinforcing coil is then wound around the thin walled tube.
  • a second layer of encapsulating material may then be deposited on the reinforcing coil using the solution draw process.
  • the kink resistant tube is then removed from the mandrel by first pulling on the ends of the mandrel to shrink it's diameter.
  • the resulting kink resistant tube exhibits superior kink resistance when subjected to severe bending stress.
  • the kink resistant tubing also has a thin wall thicknesses in comparison to the prior art.
  • Figure 1A shows an idealized schematic of the kink resistant tubing apparatus of the invention.
  • Figure IB shows the kink resistant apparatus of the invention in an idealized cross-sectional schematic.
  • Figure 2A shows a schematic of one example of the kink resistant tubing apparatus of the invention
  • Figure 2B shows one example of the kink resistant tubing apparatus of the invention in a cross section shown using a thin wall encapsulation method with a cut away of reinforcing coil supports.
  • Figure 3 shows a schematic of one example of kink resistant tubing as provided by the invention showing a plurality of reinforcing coils.
  • Figure 4 shows one example of the kink resistant tubing of the invention with a cross- sectional view of the thin wall incorporating a composite fiber reinforcement.
  • Figure 5 shows an isometric isolation view of a supporting coil as employed in one embodiment of the invention.
  • Figure 6 shows an isometric view of the thin wall kink resistant tubing apparatus of the invention incorporating a reinforcing coil.
  • Figure 7 shows the first step of manufacturing the apparatus of the invention with a mandrel coated with a thin layer of encapsulating material with the encapsulating material cut away.
  • Figure 8 shows a cross-section of a mandrel as employed by the method of the invention with a thin layer of encapsulating material.
  • Figure 9 shows a mandrel and a thin layer of encapsulating material as employed by the method of the invention with a cut away of the coil wound around the thin layer of encapsulating material.
  • Figure 10 shows a kink resistant tubing cross- sectional diagram with a reinforcing coil wrapped around the thin encapsulating layer around the mandrel as employed by one method of the invention.
  • Figure 11 shows the apparatus of the invention in its final constructed state on the mandrel.
  • Figure 12 shows a cross-section of the mandrel with the apparatus of the invention in final constructed state.
  • Figure 13 shows the method of removing the kink resistant tubing apparatus of the invention from a mandrel.
  • Figure 14 shows the kink resistant tubing apparatus being removed from the mandrel in a cross sectional view.
  • FIG. 1A shows a isometric view of one embodiment of the kink resistant tube of the invention.
  • the kink resistant tube 10 is comprised of an ideally substantially circular inside wall 18 and an outside wall 16, which is ideally substantially perfectly smooth.
  • Tube 10 is composed of encapsulating material 12 and an encapsulated coil 14 shown in Figure IB.
  • Figure IB which shows a cross- sectional diagram of the tubing apparatus of the invention shown in Figure 1A.
  • Figure IB shows a thin walled kink resistant tube 10 constructed of an encapsulating material 12 containing a spiral wound reinforcing coil 14.
  • Figure IB shows a cross-section of the tube 10 showing substantially half of the tube 10.
  • FIG. 1B shows one embodiment of the apparatus of the invention which is manufactured with the kink resistant tubing construction method of applicant's copending application KINK RESISTANT TUBING METHOD, Attorney Docket Number 1511 filed on the same date as the instant application.
  • the kink resistant tubing 20 has a ribbed surface 26 and walls 22.
  • the walls 22 contain a reinforcing material 24 as shown in Figure 2B.
  • the ribbed surface 26 comprises a plurality of ribs 25.
  • the ribbed surface 26 closely follows the contours of the reinforcing material 24 embedded within the walls 22 of the kink resistant tubing 20.
  • the kink resistant tubing 20 has a substantially smooth inside wall 28 through which various fluids may pass.
  • Each of the plurality of ribs 25 is comprised of an encapsulating material around embedded reinforcing members 24.
  • Figure 2B shows the kink resistant tubing of Figure 2A in cross-section.
  • the reinforcing members 24 are embedded in a thin encapsulating material 22.
  • the reinforcing members 24 in the example embodiment of Figure 2B are advantageously comprised of a spiral wound rectangular cross-section metallic spring which is wound around and within the encapsulating material 22.
  • Figure 2B also shows the plurality of ribs 25 of the outer surface 26 of the kink resistant tubing 20.
  • the strength and versatility of the kink resistant tube 20 is illustrated by the cross-section in Figure 2B.
  • the tubing is better able to withstand the hoop stresses of any internal pressure indicated by pressure arrows P on the tube wall 28.
  • the hoop stress in the tube encapsulating material 22 is transferred to the reinforcing members 24.
  • the reinforcing members could either be a spiral wound spring-like structure or could be separate, individual rings independent of each other.
  • the quality of the reinforcing material is advantageously such that the radial hoop stress is substantially adsorbed continuously radially around the tube by the reinforcing member.
  • FIG. 3 shows the kink resistant tubing apparatus of the invention in a two- dimensional projection with the reinforcing members 34 in a top down view.
  • Figure 3 also shows the outside surfaces 26 of the kink resistant tubing 30.
  • Encapsulating material 22 comprises the material between the reinforcing members 34.
  • the reinforcing members 34 can alternately be comprised of coiled wire made of various sizes and shapes.
  • the encapsulating material 32 is used for the total encapsulation of the reinforcing coil 34, as the elastomeric medium and for providing a smooth internal and external surface.
  • the materials of choice for the kink resistant tubing 30 are elastomers such as polyurethane or silicone rubber. Different materials will result in various levels of flexibility and kink resistance. Those skilled in the art will also recognize that when increased torque is applied to the kink resistant tubing 30 additional reinforcement in the form of multi-wire braiding, multi-filer windings and other metallic or nonmetallic reinforcement may be used.
  • the preparation of the kink resistant encapsulating materials is accomplished by following a series of steps. The preparation process is similar for all materials.
  • the solid or liquid material is first weighed.
  • the solvent is then prepared.
  • the solvent is added to the solid or liquid material in the appropriate amount to make the desired percent solids. Stirring is necessary to completely solvate plastic materials. Once the plastic is completely in solution the material is ready for use in coating applications for the kink resistant tubing of the invention.
  • the encapsulating material 22 is configured to substantially cover the reinforcing members 34. Those skilled in the art will recognize that if a reinforcing coil is found that has excellent bio- compatibility qualities that the tubing coil may not need encapsulation.
  • encapsulating materials can be used to manufacture the kink resistant tubing encapsulating material. Those include, but are not limited to, polyurethane, silicone rubber, polyurethane/polycarbonate blends, polyurethane/silicone blends, polyvinylchloride, polyimide and latex.
  • FIG. 4 shows another example of the kink resistant tubing apparatus of the invention in an enlarged cross-section diagram.
  • the kink resistant tubing 40 has the encapsulating material 42 which in this example embodiment of the invention is advantageously substantially comprised of silicone rubber.
  • the reinforcing members 44 comprise a composite wound fiber 44 which comprise the composite tubing's 40 coiled reinforcement member.
  • the outer surface 26 of the composite tube 40 is formed by the encapsulating material 42.
  • Figure 5 shows a schematic isometric drawing of an example of a reinforcing coil 50.
  • the reinforcing coil 50 in the kink resistant tubing apparatus of the invention provides radial strength and hoop strength.
  • the reinforcing coil 50 helps retain the circularity of the tubing 10 and thereby avoids buckling and kinking of the tubing 10.
  • the reinforcing coil 50 also provides a crush-resistance to the reinforcing coil.
  • the reinforcing coil 50 comprises a wire or fiber 54 which may have various cross-sectional shapes, such as, for example, rectangular, circular, or elliptical. Those skilled in the art will recognize that the cross-sectional shapes will effect the load bearing characteristics and strength characteristics of the reinforcing coil 50.
  • the cross-section 52 is rectangular with a flat face 56 and flat body 58.
  • reinforcing coil 50 materials may be used. Further, the reinforcing coil dimensions can vary as well as the reinforcing coil 50 pitch and diameter. Listed below in Table C are some of the alternative coil 50 design parameters that can be used .
  • Coil Wire Size 0.001-0.015
  • Coil Wire Material metals; stainless steel,
  • Coil Pitch 1-5 times maximum coil wire dimension
  • Coil Diameter 0.010-0.375 inches
  • FIG. 6 an isometric view of one embodiment of the kink resistant tubing 60 of the invention is shown using a wire or fiber 54.
  • the kink resistant tube 60 construction method comprises four major steps listed in Table D. These four major process steps are described in detail below with reference to Figures 7-14.
  • Figure 7 shows a mandrel 72 with a thin film encapsulating material 74.
  • the mandrel 72 provides the internal dimensions of the kink resistant tubing.
  • the mandrel may be advantageously constructed from a fluoropolymer such as PTFE or FEP, polyethylene, nylon, or possibly a ductile metal such as silver.
  • the mandrel 72 may be tubular or solid and may advantageously diametrically reduced upon the application of sufficient stretching force. If a tubing is used for the mandrel 72, a support rod, usually metallic, can be used to provide increased straightness and stiffness.
  • the mandrel is coated with a thin layer or layers of the encapsulating material 74 in solution form, using the solution draw process described below. This can require one to several coats depending on tubing specifications and encapsulating material 74 viscosity. Typically inner layers are coated to thicknesses of 0.0005-0.005 inches. Solution draw rates of 6-18 inches per minute are used to apply the encapsulating material 74.
  • the solution draw process is comprised of a number of steps. The first step is to prepare the encapsulating material in a solution form. The mandrel 72 is drawn through the solution of the encapsulating material 74. The solution is held in a container and the container contains a hole slightly larger than the size of the mandrel.
  • the mandrel is then drawn through the solution and the encapsulating material 74 is deposited on the mandrel 72.
  • the resulting encapsulating material thickness is highly controllable due to the propensity of the encapsulating material to adhere to the mandrel 72.
  • FIG. 8 shows a cross sectional diagram of the mandrel 72 and thin coating of encapsulating material 74.
  • the mandrel and encapsulating material 74 must be cured at room temperature for 6-8 hours. This allows total solvent evaporation.
  • the process variables for step one are summarized as follows in Table E.
  • the coil wrapping process involves wrapping the reinforcing coil wire 54 at the proper tension and pitch.
  • the coil wire is wrapped around the coated mandrel 72 encapsulating material substrate uniformly to the desired specifications.
  • the coil's material composition, rotational speed, tension, substrate diameter and pitch determine the size and flexibility of the coil.
  • Figure 9 shows the method of constructing the reinforcing coil 54 on the encapsulating material substrate 74.
  • the coil 54 in one embodiment of the invention is wrapped around the mandrel 72.
  • FIG. 10 shows a cross section of a kink resistant tube being constructed from the method of the invention.
  • the coated mandrel substrate 74 is placed and secured in the coil wrapping apparatus 73.
  • the coil wrapping apparatus 73 may be any suitable coil wrapping machine such as, for example, an Accuwinder (TM) machine as manufactured by the Accuwinder Company of California.
  • the coil wire 54 must adhere to the lead end of the mandrel substrate 75 and allowed to cure.
  • the substrate 74 is then wrapped from end to end using the predetermined coil wrapping parameters. Once the coil wrap is complete, the coil 54 must be locked or secured to the coated mandrel substrate 74 using adhesives. This is done at a coil termination 77. After the adhesive has cured, the wire 54 can be cut and the coiled substrate removed from the machinery 73.
  • the process variables for the coiling operation include the wire wrapping speed and coil wire tension. Experimental trials have determined that the wrapping speed should be between about 500 and 4000 rpm and the coil wire tension should be between about 25 and 200 grams.
  • Figure 11 shows the method of the invention used to apply an over coating to the coil assembly.
  • the coil 54 is over coated to a predetermined thickness using the solution draw process described above.
  • the process variables used in the solution draw of the encapsulating material are discussed above.
  • FIG 12 shows the coil 54 assembly over coated to the predetermined thickness.
  • the solution draw process has covered mandrel 72 forming kink resistant tubing 90 with encapsulating material.
  • the surface 26 of the tubing 90 is formed by the outside of encapsulating material 22 solidifying around the reinforcing coil 54.
  • Figures 13 and 14 show the method of the invention used to extract the mandrel 72 from the kink resistant tubing 90.
  • the final step is to extract the mandrel 72. This is done by securing each exposed termination of the mandrel 72 and applying sufficient and directionally opposite forces indicated by directional arrows 91 and 93 to plastically reduce the diameter of the mandrel 72 by 10-50%. Once this is accomplished, the mandrel 72 can simply be removed from the tubing assembly.

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Textile Engineering (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Composite Materials (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention se rapporte à un procédé de fabrication de tubes à paroi mince par étirage d'une solution, qu'on utilise pour fabriquer un tube résistant au vrillage (10, 20, 30, 40, 50, 60, 70, 80, 90) à partir d'une solution d'un système de solvant. Ce procédé de fabrication de tubes à paroi mince commence par créer une solution d'un polymère à paroi mince prédéterminé à partir du mélange de matières solides et d'un solvant. La solution qui en résulte est ensuite placée dans un récipient comportant un trou. Une petite couche de la solution est ensuite déposée avec une mince couche d'un matériau enveloppant (74) sur un mandrin (72), créant ainsi un tube à paroi mince (10, 20, 30, 40, 50, 60, 70, 80, 90) par évaporation du solvant. Un serpentin de renforcement (34, 54) est ensuite enroulé autour du tube à paroi mince (10, 20, 30, 40, 50, 60, 70, 80, 90). On peut ensuite déposer une seconde couche de matériau enveloppant (12, 32) sur le serpentin de renforcement en utilisant le processus d'étirage de la solution. On retire ensuite du mandrin (72) le tube résistant au vrillage (10, 20, 30, 40, 50, 60, 70, 80, 90) en tirant d'abord sur les extrémités du mandrin (72) pour obtenir un rétrécissement de son diamètre.
PCT/US1993/001303 1992-02-13 1993-02-12 Procede d'etirage d'une solution WO1993015784A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83560392A 1992-02-13 1992-02-13
US07/835,603 1992-02-13

Publications (1)

Publication Number Publication Date
WO1993015784A1 true WO1993015784A1 (fr) 1993-08-19

Family

ID=25269942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/001303 WO1993015784A1 (fr) 1992-02-13 1993-02-12 Procede d'etirage d'une solution

Country Status (2)

Country Link
AU (1) AU3666393A (fr)
WO (1) WO1993015784A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839548A1 (fr) * 1996-10-29 1998-05-06 Medtronic, Inc. Cathéter de guidage à paroi mince
US6026316A (en) * 1997-05-15 2000-02-15 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US6061587A (en) * 1997-05-15 2000-05-09 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US7048716B1 (en) 1997-05-15 2006-05-23 Stanford University MR-compatible devices
ITPD20130081A1 (it) * 2013-03-29 2014-09-30 Gioachino Coppi Catetere a deformazione controllata
WO2019115809A1 (fr) * 2017-12-15 2019-06-20 Perfuze Limited Cathéters améliorés et dispositifs et systèmes incorporant de tels cathéters
US11446469B2 (en) 2016-07-13 2022-09-20 Perfuze Limited High flexibility, kink resistant catheter shaft

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2647296A (en) * 1950-05-31 1953-08-04 Bentley Harris Mfg Company Method of manufacturing tubular insulation
US3840384A (en) * 1971-03-19 1974-10-08 Ici Ltd Method and device for coating plastics film
US4130676A (en) * 1977-03-14 1978-12-19 Matsushita Electric Industrial Co., Ltd. Coating apparatus and method
US4518633A (en) * 1984-04-06 1985-05-21 Northern Telecom Limited Production of insulated electrical conductors
US4869909A (en) * 1986-12-25 1989-09-26 Sumitomo Electric Industries Process for producing a medical vinyl chloride resin material

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2647296A (en) * 1950-05-31 1953-08-04 Bentley Harris Mfg Company Method of manufacturing tubular insulation
US3840384A (en) * 1971-03-19 1974-10-08 Ici Ltd Method and device for coating plastics film
US4130676A (en) * 1977-03-14 1978-12-19 Matsushita Electric Industrial Co., Ltd. Coating apparatus and method
US4518633A (en) * 1984-04-06 1985-05-21 Northern Telecom Limited Production of insulated electrical conductors
US4869909A (en) * 1986-12-25 1989-09-26 Sumitomo Electric Industries Process for producing a medical vinyl chloride resin material

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0839548A1 (fr) * 1996-10-29 1998-05-06 Medtronic, Inc. Cathéter de guidage à paroi mince
US6026316A (en) * 1997-05-15 2000-02-15 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US6061587A (en) * 1997-05-15 2000-05-09 Regents Of The University Of Minnesota Method and apparatus for use with MR imaging
US7048716B1 (en) 1997-05-15 2006-05-23 Stanford University MR-compatible devices
CN105228681A (zh) * 2013-03-29 2016-01-06 乔阿奇诺·戈比 受控变形导管
WO2014155210A1 (fr) * 2013-03-29 2014-10-02 Gioachino Coppi Cathéter à déformation contrôlée
ITPD20130081A1 (it) * 2013-03-29 2014-09-30 Gioachino Coppi Catetere a deformazione controllata
US20160030711A1 (en) * 2013-03-29 2016-02-04 Gioachino Coppi Controlled deformation catheters
US9662471B2 (en) 2013-03-29 2017-05-30 Gioachino Coppi Controlled deformation catheters
US11446469B2 (en) 2016-07-13 2022-09-20 Perfuze Limited High flexibility, kink resistant catheter shaft
WO2019115809A1 (fr) * 2017-12-15 2019-06-20 Perfuze Limited Cathéters améliorés et dispositifs et systèmes incorporant de tels cathéters
CN111465420A (zh) * 2017-12-15 2020-07-28 佩尔福兹有限公司 改进的导管和结合这种导管的装置和系统
US11197977B2 (en) 2017-12-15 2021-12-14 Perfuze Limited Catheters and devices and systems incorporating such catheters

Also Published As

Publication number Publication date
AU3666393A (en) 1993-09-03

Similar Documents

Publication Publication Date Title
WO1993015785A1 (fr) Tube anti-vrillage
US5472435A (en) Drainage catheter
US5704926A (en) Flexible catheter
WO1993015872A1 (fr) Procede de fabrication d'un tube anti-vrillage
US6217566B1 (en) Peripheral vascular delivery catheter
US5269752A (en) Method of extracorporeal treatment using a kink resistant catheter
US20180221623A1 (en) Medical tubing having variable characteristics and method of making same
AU2005306350B2 (en) Flexible introducer sheath
JP2024023612A (ja) 医療装置のための拡張可能なイントロデューサシース
JP4009324B2 (ja) 成形可能遠位先端を有する強化カテーテル
US8182465B2 (en) Medical device
US6186986B1 (en) Micro-catheters and methods of their manufacture
EP1539290B1 (fr) Procede de fabrication d'un element de renforcement forme pour instrument medical
JP2002505167A (ja) 形成可能な先端を有する柔軟で耐キンク性の低摩擦ガイドワイヤ及びその製造方法
JP2001501846A (ja) ガイドワイヤ追跡を高めたガイドカテーテル
US20170274179A1 (en) Hypotube Construction
EP1718241A1 (fr) Spire contre-enroulee pour gaine de protection pour embolisation
WO1993015784A1 (fr) Procede d'etirage d'une solution
US20240058593A1 (en) Cannula for intravascular blood pump
AU634060B2 (en) Indwelling catheter
WO2001007231A1 (fr) Dispositif introducteur a flexibilite variable et resistant au vrillage et procede de fabrication
US20230063196A1 (en) Intravascular blood pump in combination with catheter configured to control pump position in patient's heart
WO1999037350A1 (fr) Micro-catheters et leurs procedes de fabrication
WO2021194763A1 (fr) Cathéter guide pourvu d'un élément de renfort
JPH0368375A (ja) 医療用フレキシブルワイヤーの製造法

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU BB BG BR CA CZ FI HU JP KP KR LK MG MN MW NO NZ PL RO RU SD SK UA

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA