WO1992012345A1 - Solution pumping system with compressible pump cassette - Google Patents

Solution pumping system with compressible pump cassette Download PDF

Info

Publication number
WO1992012345A1
WO1992012345A1 PCT/US1991/009752 US9109752W WO9212345A1 WO 1992012345 A1 WO1992012345 A1 WO 1992012345A1 US 9109752 W US9109752 W US 9109752W WO 9212345 A1 WO9212345 A1 WO 9212345A1
Authority
WO
WIPO (PCT)
Prior art keywords
cassette
pump
rear body
diaphragm
compression
Prior art date
Application number
PCT/US1991/009752
Other languages
English (en)
French (fr)
Inventor
Sheldon M. Wecker
Kent D. Abrahamson
Thomas P. Joyce
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of WO1992012345A1 publication Critical patent/WO1992012345A1/en

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14224—Diaphragm type
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B7/00—Piston machines or pumps characterised by having positively-driven valving
    • F04B7/0076—Piston machines or pumps characterised by having positively-driven valving the members being actuated by electro-magnetic means

Definitions

  • the present invention relates generally to solution pumping systems for preparation and administration of patient parenteral solutions, and more particularly to a solution pumping system including a disposable pump cassette having a cassette body configured for effecting compression of an internal diaphragm of the cassette attendant to use, thereby avoiding undesirable compression set of the diaphragm material during storage prior to use.
  • This pumping system includes a combination of a pump driver and an associated removable and disposable pump cassette.
  • the pump cassette includes a self-contained positive displacement pump device, which is operated by a reciprocable pump plunger of the associated pump driver.
  • the pump driver further includes selectively operable valve actuators, which cooperate with valve mechanisms provided in the pump cassette for accurate and highly automated administration and infusion of parenteral solutions.
  • Solution pumping systems of the above infusion and compounding types employ preassembled, disposable pump cassettes.
  • Such pump cassettes typically include a cassette body including juxtaposed front and rear body members, between which is positioned a membrane-like elastomeric diaphragm.
  • the diaphragm cooperates with the front body member to provide valve mechanisms at various inlets and outlets defined by the front body member, with openings in the rear body member exposing the diaphragm for operation of the valve mechanisms by valve actuators of the associated pump driver.
  • the front body member of the cassette defines a pump chamber which, together with the internal diaphragm, provides the self-contained positive displacement pump of the cassette.
  • the rear body member defines an opening through which a reciprocable plunger of the associated pump driver is movable for operating the pump, whereby liquid can be pumped through the cassette.
  • the present invention contemplates avoiding the problems of compression set or load decay by assembling a pump cassette under relatively low compression, with the cassette being subjected to compression attendant to use so that high pumping pressures can desirably be achieved.
  • a solution pumping system embodying the principles of the present invention includes a pump driver, and a compressible pump cassette having a body formed from front and rear members which are relatively movable under the influence of a compression mechanism, which can be provided in the pump driver, or which may comprise a separate fixture fitted to the cassette before insertion of the cassette into the driver.
  • a compression mechanism which can be provided in the pump driver, or which may comprise a separate fixture fitted to the cassette before insertion of the cassette into the driver.
  • the pump cassette of the present system is configured for use with a pump driver having a reciprocable pump plunger, and a plurality of valve actuators.
  • the cassette includes a cassette body having a generally plate-like front body member, and a juxtaposed, generally plate-like rear body member.
  • the cassette further includes a membrane-like elastomeric diaphragm positioned in the cassette body between the front and rear body members.
  • the cassette body and the diaphragm cooperate to provide the cassette with at least one liquid inlet, at least one liquid outlet, and a liquid flow path for joining the liquid inlet and outlet in fluid communication with each other.
  • the cassette further includes a positive displacement pump operatively driven by the pump plunger of the associated pump driver for pumping liquid from the inlet to the outlet via the flow path defined by the cassette.
  • the front and rear body members of the cassette body are non-rigidly joined to each other for limited, relative movement toward each other for effecting compression of
  • suBs ⁇ r ⁇ sneer the elastomeric diaphragm when the pump cassette is operatively associated with the pump driver.
  • the generally plate ⁇ like front and rear body members are maintained in substantially parallel relationship to each other, with the internal diaphragm compressed therebetween.
  • the illustrated embodiment includes a plurality of fastening elements in the form of rivets.
  • Each rivet includes a shank portion and a head portion, with at least one of the front and rear body portions being movable along the shank portions of the rivets for providing the desired relative movement of the body portions.
  • the head portions act to maintain the front and rear body portions in juxtaposition to each other, with preferably relatively low compression of the internal diaphragm, such as during storage prior to use.
  • fastening elements other than rivets can be employed for movably joining the body members.
  • the illustrated embodiment of the present invention includes rivets integral with one of the body members, specifically the rear body member, with the other of the body members movable along the shank portions of the rivets.
  • the pump driver of the present system is particularly configured to effect compression of the cassette body when the pump cassette is removably positioned in the driver, thereby effecting the desired limited, relative movement of the front and rear body members of the cassette for compressing the internal diaphragm thereof.
  • the pump driver of the present system is particularly configured to effect compression of the cassette body when the pump cassette is removably positioned in the driver, thereby effecting the desired limited, relative movement of the front and rear body members of the cassette for compressing the internal diaphragm thereof.
  • UBSTITUTE SHEET pump driver includes a reciprocably movable cassette door which is movable toward and away from a cassette- receiving faceplate of the driver.
  • the pump cassette is removably positionable between the cassette door and the faceplate, whereby movement of the door toward the faceplate acts to compress the cassette body.
  • the cassette door defines clearance openings in the regions of each of the rivets of the cassette for providing clearance for the head portions of the rivets during compression of the cassette body by the pump driver.
  • a separately provided fixture functioning in the nature of a clip or clamp, can alternately be employed to permit the cassette to be compressed externally of the driver.
  • a fixture can be configured for securement to the cassette prior to disposition of the cassette in operative association with the pump driver, whereby the desired compression is maintained during use.
  • FIGURE 1 is a diagrammatic perspective view of a solution pumping system, embodied as a compounding system for parenteral solutions, embodying the principles of the present invention
  • FIGURE 2 is a diagrammatic view illustrating a casserte-receiving door mechanism of a pump driver of the present system
  • FIGURE 3 is an exploded perspective view of a disposable pump cassette of the present system illustrated, in diagrammatic form, in operative association with the pump driver of the present system;
  • FIGURE 4 is a front, elevational diagrammatic view of the pump cassette of the present system in position within the cassette door or the associated pump driver;
  • FIGURE 5 is a fragmentary, cross-sectional view taken along lines 5-5 of FIGURE 4.
  • FIGURE 6 is a view similar to FIGURE 5 illustrating compression of the pump cassette. Detailed Description
  • a solution pumping system 10 embodying the principles of the present invention.
  • the present system has been particularly configured for compounding of parenteral admixture solutions for intravenous or intramuscular administration to patients.
  • a solution pumping system embodying the principles of the present invention can be used for other applications, including infusion of parenteral solutions.
  • the solution pumping system 10 of the present invention includes a pump driver 12 and an associated disposable pump cassette 14 which is removably
  • the pump cassette 14 is of a compressible or collapsible nature, with the pump driver 12 of the illustrated embodiment configured for effecting compression of the pump cassette when it is positioned within the pump driver for use.
  • the pump cassette is typically associated with a disposable "set" of suitable tubing and connectors, which set is joined to containers of various source solutions. The resultant solution admixtures are introduced into suitable storage containers joined to the tubing set.
  • the pump cassette comprises a generally rectangular cassette body which comprises a front body member 16 and a juxtaposed rear body member 18.
  • the cassette body is preferably formed from rigid thermoplastic material, such as polycarbonate.
  • the pump cassette further includes a deformable elastomeric diaphragm 20 positioned between the front and rear body portion.
  • Diaphragm 20 cooperates with the cassette body, and in particular with the front body member 16, to define and provide at least one liquid inlet, at least one liquid outlet, and a liquid flow path joining the inlet and outlet in fluid communication.
  • the diaphragm cooperates with the front body member 16 to provide a selectively operable valve mechanism at each of the various liquid inlets and outlets.
  • the diaphragm 20 includes a plurality of inlet portions 22 respectively positioned in association with a plurality of liquid inlets 24 defined by front body member 16.
  • the diaphragm includes an outlet portion 26 which cooperates with a liquid outlet 28 defined by front body member 16.
  • the diaphragm 20 and the front body member 16 together define a liquid flow path 30 which joins the liquid inlets and the outlet in fluid communication with each other.
  • the diaphragm 20 includes a flush portion 32 arranged in confronting, cooperating relationship with a flush port 34 defined by the front body member 16, which port facilitates flushing of the cassette and associated tubing during admixture of solutions.
  • the various portions of the diaphragm 20 cooperate with the front body portion to provide a plurality of valve mechanisms, each operated by deformation and relaxation of the diaphragm 20.
  • the rear body member 18 defines a plurality of openings respectively aligned with the portions of the diaphragm which cooperate with the front body member to provide the valve mechanisms.
  • the pump driver 12 of the system includes a plurality of valve actuators 36 (two being diagrammatically illustrated in FIGURE 3) which are configured to extend through the openings in the rear body member 18 and contact the diaphragm for effecting the desired selective opening and closing of the inlets and outlets of the pump cassette.
  • Each of the valve actuators preferably comprises a solenoid-actuated arrangement for reciprocating the actuator, thereby controlling liquid flow through the respective inlet or outlet.
  • a solenoid-operated valve actuator is employed, which actuator is configured to provide the desired closing force while avoiding excessive stress of the diaphragm 20. It is preferred that the solenoid of the valve actuator employed in the
  • SUBSTITUTE SHEET present system be con igured for closing (under the influence of a return spring) in the event of power failure.
  • the pump cassette 14 includes a self-contained positive displacement pump mechanism.
  • the diaphragm 20 defines a generally circular pump portion 38, which is positioned in operative association with a pump chamber 40 defined by front body member 16.
  • Operation of the pump mechanism by deformation and relaxation of the pump portion 38, is effected by a reciprocable pump plunger 42 of the pump driver.
  • Operation of the pump can be in accordance with U.S. Patent No. 4,639,245, to Pastrone et al.
  • liquid flow is effected by reciprocation of the pump plunger 42 in timed relation to operation of selected ones of the valve actuators upstream and downstream of the pump chamber.
  • a reversible stepping motor acting through a suitable threaded connection, provides reciprocable stroking of the pump plunger for alternately deforming and relaxing the diaphragm portion 38, thus effecting positive displacement of liquid in the pump chamber 40.
  • the front and rear body members 16 and 18 of the cassette are movable toward each other for effecting compression of the diaphragm 20, to thereby securely grip and retain the diaphragm in position during pumping, as well as during operation of the various valve mechanisms.
  • the diaphragm 20 includes a relatively enlarged bead portion 44 surrounding the pump portion 38, which bead portion 44 cooperates with a pair of first clamping ribs 46 and a pair of second clamping ribs 48, respectively positioned on the front and rear body members 16 and 18 about the pump chamber.
  • the first and second clamping ribs are engageable with the diaphragm on respective opposite sides thereof, with the bead portion 44 held and gripped therebetween.
  • the first and second clamping ribs are relatively movable toward each other for effecting compression of the diaphragm 20.
  • the diaphragm 20 can be configured to include air detection portions 50 which project rearwardly through rear body member 18 so that a portion of the liquid flow path extends rearwardly from the rear body member.
  • Each of the air detection portions 50 is received within a respective air detector 52 (one being illustrated in FIGURE 3) .
  • the diaphragm 20 is preferably formed from a translucent, silicone-based elastomer, with the air detector 52 preferably configured to ultrasonically or optically detect the presence of air, and thus the absence of liquid, in the respective portion 50.
  • the cassette includes a plurality of rivets 56 or like fastening members which are each configured to extend within respective openings 58 for staking the body members to each other.
  • the rivets can be separately provided, it is presently preferred that the rivets 56 be integral with either one of the body portions (integral with rear body portion 18 in the illustrated embodiment) , with the other of the body members (front body member 16 in the illustrated form) , being movable along the shank portions of the rivets 56.
  • Each of the rivets 56 also includes a deformed head portion, with the head portions collectively retaining the body members together after assembly of the cassette.
  • the rivets are preferably configured for heat-deformation (such as by ultrasonic staking) , and thus may be of a generally hollow configuration, as illustrated, to facilitate such heat-deformation subsequent to juxtaposition of the body members with the diaphragm 20 therebetween.
  • the cassette 14 be assembled with relatively low compression of the various components, and thus relatively low stress, to avoid problems associated with compression set or load decay during storage prior to use.
  • the diaphragm 20 can be compressed on the order of about 0.005 inches during assembly, with the head portions of the rivets 56 deformed to maintain the assembly in this configuration. Subsequent compression of the cassette 14 by the pump driver 12 acts to relatively move the body members, with the front body member 16 moving along the shank portions of the rivets 56 for effecting the desired degree of compression of the diaphragm 20 for high-pressure operation.
  • the cassette 14 can optionally be configured to include one or more positive stop elements or the like for limiting the relative movement of the front and rear body members 16 and 18, thereby limiting the compression of the elastomeric diaphragm 20.
  • Such an arrangement can take the form of one or more stop flanges 59, such as shown in phantom line in FIGURES 5 and 6, integral with one of the front and rear body members (the rear body member 18 in the illustrated form) .
  • the rivets 56 joining the body members can similarly be provided with such a travel- limiting arrangement. This construction acts to limit the extent of diaphragm compression to a preselected value, and is believed to desirably reduce tolerance stack-up during manufacture and assembly.
  • the cassette- receiving door mechanism of the pump driver 12 is diagrammatically illustrated.
  • the mechanism includes a reciprocable cassette door 62 generally within which the cassette 14 is removably positionable.
  • the cassette door 62 is movable generally inwardly and outwardly relative to a faceplate 64 (not shown in FIGURE 3; see FIGURES 5 and 6) for effecting compression of the pump cassette 14 therebetween.
  • a faceplate 64 not shown in FIGURE 3; see FIGURES 5 and 6
  • compression of the cassette 14 be effected by the action of the door 62
  • the desired compression can alternately be provided, externally of the pump driver 12, such as by the provision of a separate clamp-like or clip-like fixture fitted to the cassette.
  • Such a fixture, diagrammatically illustrated at 61 in FIGURE 6 can be fitted to the cassette prior to its positioning in association with the pump driver 12, thereby maintaining the cassette in compression during use.
  • the illustrated embodiment includes a pair of support arms 66 on which the reciprocable cassette door 62 is mounted, with the arms 66 in turn mounted on a shaft 68.
  • a pair of roller cams 70 are joined to the shaft 68, with the cams 70 being configured for cooperative reaction against a pair of fixed end beam springs 72 attendant to vertical movement of operating lever 74.
  • FIGURES 5 and 6 illustrate compression of the cassette 14, including relative movement of the front and rear body members 16 and 18 for compression of diaphragm 20.
  • the degree of compression is selected to permit operation of the pump cassette at the desired high pressures without any leakage of liquid from the flow path 30, or the pump chamber 40.
  • the door 62 which acts to effect compression of the pump cassette 14, preferably defines clearance openings 76 (one being illustrated) for providing clearance for the head portions of the rivets 56 during compression of the cassette body by the door mechanism of the pump driver 12.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Reciprocating Pumps (AREA)
PCT/US1991/009752 1990-12-28 1991-12-27 Solution pumping system with compressible pump cassette WO1992012345A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US635,906 1990-12-28
US07/635,906 US5098262A (en) 1990-12-28 1990-12-28 Solution pumping system with compressible pump cassette

Publications (1)

Publication Number Publication Date
WO1992012345A1 true WO1992012345A1 (en) 1992-07-23

Family

ID=24549602

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/009752 WO1992012345A1 (en) 1990-12-28 1991-12-27 Solution pumping system with compressible pump cassette

Country Status (4)

Country Link
US (1) US5098262A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0564575A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2111119A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1992012345A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000033898A1 (de) 1998-12-09 2000-06-15 Rheotec Ag Pumpschlauchsystem zur peristaltischen förderung von flüssigen und gasförmigen medien

Families Citing this family (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935099A (en) 1992-09-09 1999-08-10 Sims Deltec, Inc. Drug pump systems and methods
US6241704B1 (en) * 1901-11-22 2001-06-05 Sims Deltec, Inc. Drug pump systems and methods
US5554013A (en) * 1992-05-01 1996-09-10 Mcgaw, Inc. Disposable cassette with negative head height fluid supply
US5344292A (en) * 1992-08-20 1994-09-06 Ryder International Corporation Fluid pumping system and apparatus
DE4336336A1 (de) * 1992-11-23 1994-05-26 Lang Volker Kasetteninfusionssystem
CA2145295A1 (en) * 1992-12-30 1994-07-21 Kent D. Abrahamson Diaphragm for solution pumping system
US5474683A (en) * 1993-03-03 1995-12-12 Deka Products Limited Partnership Peritoneal dialysis systems and methods employing pneumatic pressure and temperature-corrected liquid volume measurements
US5350357A (en) 1993-03-03 1994-09-27 Deka Products Limited Partnership Peritoneal dialysis systems employing a liquid distribution and pumping cassette that emulates gravity flow
DE69413166T2 (de) * 1993-03-03 1999-05-12 Deka Products Ltd. Partnership, Manchester, N.H. Vorrichtung zur peritonaldialyse mit einer zur luftabscheidung ausgerüsteten flüssigkeitsverteil- und pumpenkassette.
US5438510A (en) * 1993-03-03 1995-08-01 Deka Products Limited Partnership User interface and monitoring functions for automated peritoneal dialysis systems
US5431626A (en) * 1993-03-03 1995-07-11 Deka Products Limited Partnership Liquid pumping mechanisms for peritoneal dialysis systems employing fluid pressure
US5385540A (en) * 1993-05-26 1995-01-31 Quest Medical, Inc. Cardioplegia delivery system
US5431627A (en) * 1993-11-12 1995-07-11 Abbott Laboratories Cassette identification system for use with a multi-program drug infusion pump
US5531697A (en) * 1994-04-15 1996-07-02 Sims Deltec, Inc. Systems and methods for cassette identification for drug pumps
US6216573B1 (en) 1995-06-07 2001-04-17 Hydrocision, Inc. Fluid jet cutting system
US6165154A (en) * 1995-06-07 2000-12-26 Deka Products Limited Partnership Cassette for intravenous-line flow-control system
US5853386A (en) 1996-07-25 1998-12-29 Alaris Medical Systems, Inc. Infusion device with disposable elements
DE69828619T2 (de) 1997-08-22 2006-01-05 Deka Products Ltd. Partnership System, verfahren und kassette zum mischen und abgeben intravenösern medikamente
DE19907222A1 (de) * 1999-02-19 2000-08-31 Braun Gmbh Pumpvorrichtung
JP3834745B2 (ja) * 1999-05-11 2006-10-18 応研精工株式会社 小型ポンプ
US6877713B1 (en) 1999-07-20 2005-04-12 Deka Products Limited Partnership Tube occluder and method for occluding collapsible tubes
US8412377B2 (en) 2000-01-24 2013-04-02 Irobot Corporation Obstacle following sensor scheme for a mobile robot
US6497676B1 (en) 2000-02-10 2002-12-24 Baxter International Method and apparatus for monitoring and controlling peritoneal dialysis therapy
US6956348B2 (en) 2004-01-28 2005-10-18 Irobot Corporation Debris sensor for cleaning apparatus
DE10053441B4 (de) * 2000-10-27 2004-04-15 Fresenius Medical Care Deutschland Gmbh Disposablekassette mit Dichtungsmembran sowie Ventilaktor hierfür
FR2817754B1 (fr) * 2000-12-08 2003-09-12 Hospal Internat Marketing Man Dispositif pour la mesure de pression comportant une membrane moulee dans une cassette
US7571511B2 (en) 2002-01-03 2009-08-11 Irobot Corporation Autonomous floor-cleaning robot
US6690134B1 (en) 2001-01-24 2004-02-10 Irobot Corporation Method and system for robot localization and confinement
CA2484061C (en) 2001-04-27 2008-07-15 Hydrocision, Inc. High pressure pumping cartridges for medical and surgical pumping and infusion applications
US7663333B2 (en) 2001-06-12 2010-02-16 Irobot Corporation Method and system for multi-mode coverage for an autonomous robot
US20030125662A1 (en) 2002-01-03 2003-07-03 Tuan Bui Method and apparatus for providing medical treatment therapy based on calculated demand
US8504179B2 (en) 2002-02-28 2013-08-06 Smiths Medical Asd, Inc. Programmable medical infusion pump
US8250483B2 (en) 2002-02-28 2012-08-21 Smiths Medical Asd, Inc. Programmable medical infusion pump displaying a banner
AU2003230862A1 (en) 2002-04-11 2003-10-27 Deka Products Limited Partnership System and method for delivering a target volume of fluid
US20030217957A1 (en) * 2002-05-24 2003-11-27 Bowman Joseph H. Heat seal interface for a disposable medical fluid unit
EP1511524B1 (en) * 2002-05-24 2015-02-25 Baxter International Inc. Automated dialysis system
US7153286B2 (en) * 2002-05-24 2006-12-26 Baxter International Inc. Automated dialysis system
US7087036B2 (en) * 2002-05-24 2006-08-08 Baxter International Inc. Fail safe system for operating medical fluid valves
US7175606B2 (en) 2002-05-24 2007-02-13 Baxter International Inc. Disposable medical fluid unit having rigid frame
US20030220607A1 (en) * 2002-05-24 2003-11-27 Don Busby Peritoneal dialysis apparatus
US6764761B2 (en) * 2002-05-24 2004-07-20 Baxter International Inc. Membrane material for automated dialysis system
DE10224750A1 (de) 2002-06-04 2003-12-24 Fresenius Medical Care De Gmbh Vorrichtung zur Behandlung einer medizinischen Flüssigkeit
US7238164B2 (en) 2002-07-19 2007-07-03 Baxter International Inc. Systems, methods and apparatuses for pumping cassette-based therapies
EP1523347B1 (en) 2002-07-19 2011-05-18 Baxter International Inc. Systems and methods for performing peritoneal dialysis
DE10239597B4 (de) * 2002-08-28 2005-03-17 Fresenius Medical Care Deutschland Gmbh Einwegkassette
US8428778B2 (en) 2002-09-13 2013-04-23 Irobot Corporation Navigational control system for a robotic device
WO2004094823A2 (en) 2003-04-23 2004-11-04 Biovalve Technologies, Inc. Hydraulically actuated pump for long duration medicament administration
EP1680155B2 (en) 2003-10-28 2015-11-04 Baxter International Inc. Dialysis machine with improved integrity test
US8158102B2 (en) * 2003-10-30 2012-04-17 Deka Products Limited Partnership System, device, and method for mixing a substance with a liquid
US7632078B2 (en) * 2003-10-30 2009-12-15 Deka Products Limited Partnership Pump cassette bank
US7662139B2 (en) * 2003-10-30 2010-02-16 Deka Products Limited Partnership Pump cassette with spiking assembly
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
US7776006B2 (en) * 2003-11-05 2010-08-17 Baxter International Inc. Medical fluid pumping system having real time volume determination
US7332890B2 (en) 2004-01-21 2008-02-19 Irobot Corporation Autonomous robot auto-docking and energy management systems and methods
US8954336B2 (en) 2004-02-23 2015-02-10 Smiths Medical Asd, Inc. Server for medical device
US20050209563A1 (en) * 2004-03-19 2005-09-22 Peter Hopping Cassette-based dialysis medical fluid therapy systems, apparatuses and methods
SG174000A1 (en) 2004-06-24 2011-09-29 Irobot Corp Remote control scheduler and method for autonomous robotic device
US9089636B2 (en) * 2004-07-02 2015-07-28 Valeritas, Inc. Methods and devices for delivering GLP-1 and uses thereof
US7706917B1 (en) 2004-07-07 2010-04-27 Irobot Corporation Celestial navigation system for an autonomous robot
US8972052B2 (en) 2004-07-07 2015-03-03 Irobot Corporation Celestial navigation system for an autonomous vehicle
US7389156B2 (en) * 2005-02-18 2008-06-17 Irobot Corporation Autonomous surface cleaning robot for wet and dry cleaning
US7620476B2 (en) 2005-02-18 2009-11-17 Irobot Corporation Autonomous surface cleaning robot for dry cleaning
EP2289384B1 (en) * 2005-02-18 2013-07-03 iRobot Corporation Autonomous surface cleaning robot for wet and dry cleaning
US8392021B2 (en) 2005-02-18 2013-03-05 Irobot Corporation Autonomous surface cleaning robot for wet cleaning
US7935074B2 (en) * 2005-02-28 2011-05-03 Fresenius Medical Care Holdings, Inc. Cassette system for peritoneal dialysis machine
US8930023B2 (en) 2009-11-06 2015-01-06 Irobot Corporation Localization by learning of wave-signal distributions
US8197231B2 (en) 2005-07-13 2012-06-12 Purity Solutions Llc Diaphragm pump and related methods
EP2267568B1 (en) 2005-12-02 2014-09-24 iRobot Corporation Autonomous coverage robot navigation system
EP2544066B1 (en) 2005-12-02 2018-10-17 iRobot Corporation Robot system
US8584305B2 (en) 2005-12-02 2013-11-19 Irobot Corporation Modular robot
KR101300493B1 (ko) 2005-12-02 2013-09-02 아이로보트 코퍼레이션 커버리지 로봇 이동성
SG173319A1 (en) 2006-03-30 2011-08-29 Valeritas Inc Multi-cartridge fluid delivery device
US20140199193A1 (en) 2007-02-27 2014-07-17 Deka Products Limited Partnership Blood treatment systems and methods
US10537671B2 (en) 2006-04-14 2020-01-21 Deka Products Limited Partnership Automated control mechanisms in a hemodialysis apparatus
CA3123166A1 (en) 2006-04-14 2007-10-25 Deka Products Limited Partnership Systems, devices and methods for fluid pumping, heat exchange, thermal sensing, and conductivity sensing
EP2394553B1 (en) 2006-05-19 2016-04-20 iRobot Corporation Removing debris from cleaning robots
US8417383B2 (en) 2006-05-31 2013-04-09 Irobot Corporation Detecting robot stasis
US8435206B2 (en) 2006-08-03 2013-05-07 Smiths Medical Asd, Inc. Interface for medical infusion pump
US8149131B2 (en) 2006-08-03 2012-04-03 Smiths Medical Asd, Inc. Interface for medical infusion pump
US8965707B2 (en) 2006-08-03 2015-02-24 Smiths Medical Asd, Inc. Interface for medical infusion pump
US8858526B2 (en) 2006-08-03 2014-10-14 Smiths Medical Asd, Inc. Interface for medical infusion pump
US20080058712A1 (en) * 2006-08-31 2008-03-06 Plahey Kulwinder S Peritoneal dialysis machine with dual voltage heater circuit and method of operation
US7731689B2 (en) 2007-02-15 2010-06-08 Baxter International Inc. Dialysis system having inductive heating
US8558964B2 (en) 2007-02-15 2013-10-15 Baxter International Inc. Dialysis system having display with electromagnetic compliance (“EMC”) seal
US8361023B2 (en) * 2007-02-15 2013-01-29 Baxter International Inc. Dialysis system with efficient battery back-up
US7998115B2 (en) * 2007-02-15 2011-08-16 Baxter International Inc. Dialysis system having optical flowrate detection
US8870812B2 (en) * 2007-02-15 2014-10-28 Baxter International Inc. Dialysis system having video display with ambient light adjustment
US8366655B2 (en) 2007-02-27 2013-02-05 Deka Products Limited Partnership Peritoneal dialysis sensor apparatus systems, devices and methods
KR20220131550A (ko) 2007-02-27 2022-09-28 데카 프로덕츠 리미티드 파트너쉽 혈액투석 시스템
US8491184B2 (en) 2007-02-27 2013-07-23 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US8042563B2 (en) 2007-02-27 2011-10-25 Deka Products Limited Partnership Cassette system integrated apparatus
US9028691B2 (en) 2007-02-27 2015-05-12 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US8409441B2 (en) 2007-02-27 2013-04-02 Deka Products Limited Partnership Blood treatment systems and methods
US10463774B2 (en) 2007-02-27 2019-11-05 Deka Products Limited Partnership Control systems and methods for blood or fluid handling medical devices
RU2472967C2 (ru) * 2007-03-13 2013-01-20 Медела Холдинг Аг Узел мембранного отсасывателя
KR20140123110A (ko) 2007-05-09 2014-10-21 아이로보트 코퍼레이션 소형 자율 커버리지 로봇
US11833281B2 (en) 2008-01-23 2023-12-05 Deka Products Limited Partnership Pump cassette and methods for use in medical treatment system using a plurality of fluid lines
US10195330B2 (en) 2008-01-23 2019-02-05 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US11975128B2 (en) 2008-01-23 2024-05-07 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US10201647B2 (en) 2008-01-23 2019-02-12 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
EP2254615B1 (en) 2008-01-23 2016-03-23 DEKA Products Limited Partnership Fluid flow occluder and methods of use for medical treatment systems
US8133197B2 (en) 2008-05-02 2012-03-13 Smiths Medical Asd, Inc. Display for pump
US9514283B2 (en) 2008-07-09 2016-12-06 Baxter International Inc. Dialysis system having inventory management including online dextrose mixing
US8062513B2 (en) 2008-07-09 2011-11-22 Baxter International Inc. Dialysis system and machine having therapy prescription recall
US12171922B2 (en) 2008-08-27 2024-12-24 Deka Products Limited Partnership Blood treatment systems and methods
US8192401B2 (en) 2009-03-20 2012-06-05 Fresenius Medical Care Holdings, Inc. Medical fluid pump systems and related components and methods
JP2012533357A (ja) 2009-07-15 2012-12-27 フレゼニウス メディカル ケア ホールディングス インコーポレーテッド 医療用流体カセットおよびその関連システムおよび方法
US8720913B2 (en) 2009-08-11 2014-05-13 Fresenius Medical Care Holdings, Inc. Portable peritoneal dialysis carts and related systems
ES2364516B1 (es) * 2010-02-25 2012-09-26 Salvador Merce Vives Equipo de pulsación hidráulica aplicable a una bomba de perfusión.
CA3024418C (en) 2010-07-07 2024-05-28 Matthew J. Finch Medical treatment system and methods using a plurality of fluid lines
DE102010053973A1 (de) 2010-12-09 2012-06-14 Fresenius Medical Care Deutschland Gmbh Medizinisches Gerät mit einer Heizung
WO2012087798A2 (en) 2010-12-20 2012-06-28 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US8777590B2 (en) * 2010-12-22 2014-07-15 Hospira, Inc. Fluid delivery device identification and loading system
US9624915B2 (en) 2011-03-09 2017-04-18 Fresenius Medical Care Holdings, Inc. Medical fluid delivery sets and related systems and methods
CA2833537C (en) 2011-04-21 2019-07-30 Fresenius Medical Care Holdings, Inc. Fastening mechanisms for medical fluid pumping systems and related devices and methods
US9999717B2 (en) 2011-05-24 2018-06-19 Deka Products Limited Partnership Systems and methods for detecting vascular access disconnection
CA3240652A1 (en) 2011-05-24 2012-11-29 Deka Products Limited Partnership Blood treatment systems and methods
SG10201809897VA (en) 2011-05-24 2018-12-28 Deka Products Lp Hemodialysis System
US20130081697A1 (en) * 2011-09-30 2013-04-04 Depuy Mitek, Inc. Fluidic manifold
US9186449B2 (en) 2011-11-01 2015-11-17 Fresenius Medical Care Holdings, Inc. Dialysis machine support assemblies and related systems and methods
EP3498316B1 (en) 2011-11-04 2020-07-22 DEKA Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US12303631B2 (en) 2011-11-04 2025-05-20 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US9610392B2 (en) 2012-06-08 2017-04-04 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
US9500188B2 (en) 2012-06-11 2016-11-22 Fresenius Medical Care Holdings, Inc. Medical fluid cassettes and related systems and methods
SG11201505142TA (en) 2013-01-28 2015-07-30 Smiths Medical Asd Inc Medication safety devices and methods
US9561323B2 (en) 2013-03-14 2017-02-07 Fresenius Medical Care Holdings, Inc. Medical fluid cassette leak detection methods and devices
JP6456911B2 (ja) * 2013-03-15 2019-01-23 デカ・プロダクツ・リミテッド・パートナーシップ 血液処置システムおよび方法
US9714650B2 (en) 2013-06-11 2017-07-25 Matthew G. Morris, Jr. Pumping system
US10117985B2 (en) 2013-08-21 2018-11-06 Fresenius Medical Care Holdings, Inc. Determining a volume of medical fluid pumped into or out of a medical fluid cassette
US20150133861A1 (en) 2013-11-11 2015-05-14 Kevin P. McLennan Thermal management system and method for medical devices
US12026271B2 (en) 2014-05-27 2024-07-02 Deka Products Limited Partnership Control systems and methods for blood or fluid handling medical devices
JP6783147B2 (ja) 2014-06-05 2020-11-11 デカ・プロダクツ・リミテッド・パートナーシップ ポンピングチャンバにおける流体体積の変化を計算するシステム
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
JP6855154B2 (ja) * 2014-09-02 2021-04-07 キヤノンメディカルシステムズ株式会社 核酸検出カセット
JP6855155B2 (ja) * 2014-09-02 2021-04-07 キヤノンメディカルシステムズ株式会社 核酸検出カセット
EP3190169A4 (en) 2014-09-02 2018-03-21 Toshiba Medical Systems Corporation Nucleic acid detection cassette
US10293102B2 (en) 2014-12-01 2019-05-21 Carefusion 2200, Inc. Pump cassettes with piston and infusion pump systems
US10376639B2 (en) 2014-12-01 2019-08-13 Carefusion 2200, Inc. Valving system for infusion cassette
US10363360B2 (en) 2014-12-01 2019-07-30 Carefusion 2200, Inc. Pump cassettes with slider and infusion pump systems
US10245373B2 (en) 2014-12-01 2019-04-02 Carefusion 2200, Inc. Pump cassettes with positioning feature and infusion pump systems
DE202015102187U1 (de) * 2015-04-30 2016-08-04 Ulrich Gmbh & Co. Kg Vorrichtung zum Transfer eines Fluids
WO2016189419A1 (en) 2015-05-26 2016-12-01 Hospira, Nc. Disposable infusion fluid delivery device for programmable large volume drug delivery
EP4026893A3 (en) 2015-10-09 2022-09-28 DEKA Products Limited Partnership Fluid pumping and bioreactor system
EP3429659B1 (en) 2016-03-18 2022-03-02 DEKA Products Limited Partnership Pressure control gaskets for operating pump cassette membranes
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
US11179516B2 (en) 2017-06-22 2021-11-23 Baxter International Inc. Systems and methods for incorporating patient pressure into medical fluid delivery
AU2018361950B2 (en) * 2017-10-31 2024-08-01 Nextkidney Sa Automated extracorporeal blood treatment apparatus
CA3095364A1 (en) 2018-03-30 2019-10-03 Deka Products Limited Partnership Liquid pumping cassettes, pressure distribution manifold, and related methods
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
USD1052728S1 (en) 2021-11-12 2024-11-26 Icu Medical, Inc. Medical fluid infusion pump

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4303376A (en) * 1979-07-09 1981-12-01 Baxter Travenol Laboratories, Inc. Flow metering cassette and controller
US4411603A (en) * 1981-06-24 1983-10-25 Cordis Dow Corp. Diaphragm type blood pump for medical use
US4758238A (en) * 1985-09-25 1988-07-19 Alcon Laboratories, Inc. Fast response tubeless vacuum aspiration collection cassette
US5062774A (en) * 1989-12-01 1991-11-05 Abbott Laboratories Solution pumping system including disposable pump cassette

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818186A (en) * 1987-05-01 1989-04-04 Abbott Laboratories Drive mechanism for disposable fluid infusion pumping cassette

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4303376A (en) * 1979-07-09 1981-12-01 Baxter Travenol Laboratories, Inc. Flow metering cassette and controller
US4411603A (en) * 1981-06-24 1983-10-25 Cordis Dow Corp. Diaphragm type blood pump for medical use
US4758238A (en) * 1985-09-25 1988-07-19 Alcon Laboratories, Inc. Fast response tubeless vacuum aspiration collection cassette
US5062774A (en) * 1989-12-01 1991-11-05 Abbott Laboratories Solution pumping system including disposable pump cassette

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000033898A1 (de) 1998-12-09 2000-06-15 Rheotec Ag Pumpschlauchsystem zur peristaltischen förderung von flüssigen und gasförmigen medien
DE19856744A1 (de) * 1998-12-09 2000-06-15 Winfried Schimmelpfennig Pumpschlauchsystem zur peristaltischen Förderung von flüssigen oder gasförmigen Medien
DE19856744C2 (de) * 1998-12-09 2003-06-26 Plasmaselect Ag Pumpschlauchsystem zur peristaltischen Förderung von flüssigen oder gasförmigen Medien

Also Published As

Publication number Publication date
EP0564575A1 (en) 1993-10-13
CA2111119A1 (en) 1992-07-23
EP0564575A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-03-16
US5098262A (en) 1992-03-24

Similar Documents

Publication Publication Date Title
US5098262A (en) Solution pumping system with compressible pump cassette
CN1117236C (zh) 阀组件
US5378126A (en) Diaphragm cassette for solution pumping system
US5415528A (en) Solution pumping for maximizing output while minimizing uneven pumping pressures
US6554587B2 (en) Pump and diaphragm for use therein
US4305702A (en) Pump with expandable chamber
US8087906B2 (en) Fluid pump with disposable component
EP2077888B1 (en) Micro-valve
US4381005A (en) Intravenous pump chamber
US9011379B2 (en) Infusion pump cassette with anti-free-flow valve mechanism
US4515591A (en) Disposable syringe cartridge for fluid delivery apparatus
WO2011020600A1 (de) Einwegelement, system zum pumpen sowie verfahren zum pumpen einer flüssigkeit
JPH08238312A (ja) 管セット及び灌注装置
SG172933A1 (en) Infusion pump cassette with anti-free-flow valve mechanism
IE901698L (en) Pump apparatus for biomedical use
EP1141546A1 (en) Piezoelectric micropump
WO2010088144A1 (en) Infusion pump cassette with ant i -free -flow valve mechanism
CA2156827A1 (en) A pump
CN216342702U (zh) 一种隔膜式电磁泵及使用该泵的装置
AU2007310633B2 (en) Micro-valve
HK40024890A (en) Solenoid pump
HK40024890B (en) Solenoid pump

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LU MC NL SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 1992903511

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2111119

Country of ref document: CA

WWP Wipo information: published in national office

Ref document number: 1992903511

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1992903511

Country of ref document: EP