WO1992009271A1 - Composition for solid pharmaceutical preparations containing active vitamins d3 and process for preparation thereof - Google Patents

Composition for solid pharmaceutical preparations containing active vitamins d3 and process for preparation thereof Download PDF

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Publication number
WO1992009271A1
WO1992009271A1 PCT/US1991/002846 US9102846W WO9209271A1 WO 1992009271 A1 WO1992009271 A1 WO 1992009271A1 US 9102846 W US9102846 W US 9102846W WO 9209271 A1 WO9209271 A1 WO 9209271A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
vitamins
pharmaceutical preparations
solid pharmaceutical
active vitamins
Prior art date
Application number
PCT/US1991/002846
Other languages
English (en)
French (fr)
Inventor
Motonari Okumura
Masahiro Ariyoshi
Takeshi Noguchi
Original Assignee
Sumitomo Pharmaceuticals Co., Ltd.
Wisconsin Alumni Research Foundation
Taisho Pharmaceuticals Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co., Ltd., Wisconsin Alumni Research Foundation, Taisho Pharmaceuticals Co., Ltd. filed Critical Sumitomo Pharmaceuticals Co., Ltd.
Publication of WO1992009271A1 publication Critical patent/WO1992009271A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PCT/US1991/002846 1990-11-28 1991-04-25 Composition for solid pharmaceutical preparations containing active vitamins d3 and process for preparation thereof WO1992009271A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2/332013 1990-11-28
JP2332013A JPH04198129A (ja) 1990-11-28 1990-11-28 活性型ビタミンｄ↓３類含有組成物

Publications (1)

Publication Number Publication Date
WO1992009271A1 true WO1992009271A1 (en) 1992-06-11

Family

ID=18250168

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1991/002846 WO1992009271A1 (en) 1990-11-28 1991-04-25 Composition for solid pharmaceutical preparations containing active vitamins d3 and process for preparation thereof

Country Status (4)

Country Link
EP (1) EP0559645A1 (ja)
JP (1) JPH04198129A (ja)
AU (1) AU8096591A (ja)
WO (1) WO1992009271A1 (ja)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994000128A1 (en) * 1992-06-22 1994-01-06 Lunar Corporation ORAL 1α-HYDROXYPREVITAMIN D
EP0588539A1 (en) * 1992-09-18 1994-03-23 Teva Pharmaceutical Industries, Ltd. Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
EP0508756B1 (en) * 1991-04-09 1996-10-23 Takeda Chemical Industries, Ltd. Stabilized vitamin D preparation
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
US6004996A (en) * 1997-02-05 1999-12-21 Hoffman-La Roche Inc. Tetrahydrolipstatin containing compositions
KR100688618B1 (ko) * 2001-09-12 2007-03-09 주식회사 유유 비타민 ｄ 경구투여용 서방성 약제 조성물
WO2007068287A1 (en) * 2005-12-15 2007-06-21 Laboratoria Qualiphar Sustained release vitamin preparation
EP2468265A3 (en) * 2010-12-04 2013-01-02 DEEF Pharmaceutical Industries Co. Homogeneous preparations containing vitamin D
US8703187B2 (en) 2007-04-25 2014-04-22 Warner Chilcott Company, Llc Vitamin D content uniformity in pharmaceutical dosage forms
US10300078B2 (en) 2013-03-15 2019-05-28 Opko Ireland Global Holdings, Ltd. Stabilized modified release vitamin D formulation and method of administering same
US10493084B2 (en) 2014-08-07 2019-12-03 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US10668089B2 (en) 2006-06-21 2020-06-02 Opko Ireland Global Holdings, Ltd. Method of treating and preventing secondary hyperparathyroidism
US11007204B2 (en) 2006-02-03 2021-05-18 Opko Renal, Llc Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
US11154509B2 (en) 2007-04-25 2021-10-26 Eirgen Pharma Ltd. Methods for controlled release oral dosage of a vitamin D compound
US11173168B2 (en) 2016-03-28 2021-11-16 Eirgen Pharma Ltd. Methods of treating vitamin D insufficiency in chronic kidney disease
US11672809B2 (en) 2010-03-29 2023-06-13 Eirgen Pharma Ltd. Methods and compositions for reducing parathyroid levels
US11752158B2 (en) 2007-04-25 2023-09-12 Eirgen Pharma Ltd. Method of treating vitamin D insufficiency and deficiency

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7034595B2 (ja) * 2016-03-23 2022-03-14 株式会社ファンケル ビタミンｄ３安定化組成物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116755A1 (en) * 1983-02-22 1984-08-29 Teijin Limited Composition for solid pharmaceutical preparations of active vitamins D3 and process for preparation thereof
EP0215596A2 (en) * 1985-09-05 1987-03-25 Teijin Limited Composition for injection of active type vitamins D3
EP0387808A2 (en) * 1989-03-13 1990-09-19 Ss Pharmaceutical Co., Ltd. Compositions for the preparation of dosage-form active vitamins D3 and process for preparing stable dosage-form active vitamins D3 by using the same
EP0413727A1 (en) * 1988-04-26 1991-02-27 Ellco Food Ab BLOOD PLATELET LYSATE, PROCESS FOR PREPARING SAME, AND CELL CULTURE MEDIUM CONTAINING SUCH A LYSATE.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116755A1 (en) * 1983-02-22 1984-08-29 Teijin Limited Composition for solid pharmaceutical preparations of active vitamins D3 and process for preparation thereof
EP0215596A2 (en) * 1985-09-05 1987-03-25 Teijin Limited Composition for injection of active type vitamins D3
EP0413727A1 (en) * 1988-04-26 1991-02-27 Ellco Food Ab BLOOD PLATELET LYSATE, PROCESS FOR PREPARING SAME, AND CELL CULTURE MEDIUM CONTAINING SUCH A LYSATE.
EP0387808A2 (en) * 1989-03-13 1990-09-19 Ss Pharmaceutical Co., Ltd. Compositions for the preparation of dosage-form active vitamins D3 and process for preparing stable dosage-form active vitamins D3 by using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
STN International Information Services, Data Base: Chemical Abstracts, Accession Number: 100(12): 91354r; & JP-A-58206533 (TEIJIN LTD) 1 December 1983 *

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0508756B1 (en) * 1991-04-09 1996-10-23 Takeda Chemical Industries, Ltd. Stabilized vitamin D preparation
US5614513A (en) * 1992-06-22 1997-03-25 Bone Care International, Inc. Oral 1α-hydroxyprevitamin D
US5529991A (en) * 1992-06-22 1996-06-25 Lunar Corporation Oral 1α-hydroxyprevitamin D
US6150346A (en) * 1992-06-22 2000-11-21 Bone Care International, Inc. Method and composition for treating or preventing osteoporosis
US5622941A (en) * 1992-06-22 1997-04-22 Lunar Corporation Oral 1 α-hydroxyprevitamin D
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
WO1994000128A1 (en) * 1992-06-22 1994-01-06 Lunar Corporation ORAL 1α-HYDROXYPREVITAMIN D
US6133250A (en) * 1992-06-22 2000-10-17 Bone Care International, Inc. Oral 1α-hydroxyprevitamin D in methods for increasing blood level of activated vitamin D
US6147064A (en) * 1992-06-22 2000-11-14 Bone Care International, Inc. Oral 1α-hydroxyprevitamin D in composition and method for treating psoriasis
AU667742B2 (en) * 1992-09-18 1996-04-04 Teva Pharmaceutical Industries Ltd. Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
US5565442A (en) * 1992-09-18 1996-10-15 Teva Pharmaceutical Industries Ltd. Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
EP0588539A1 (en) * 1992-09-18 1994-03-23 Teva Pharmaceutical Industries, Ltd. Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3
US5804573A (en) * 1992-09-18 1998-09-08 Teva Pharmaceutical Industries Ltd. Stabilized pharmaceutical composition containing derivative of vitamins D2 and D3
US6004996A (en) * 1997-02-05 1999-12-21 Hoffman-La Roche Inc. Tetrahydrolipstatin containing compositions
KR100688618B1 (ko) * 2001-09-12 2007-03-09 주식회사 유유 비타민 ｄ 경구투여용 서방성 약제 조성물
WO2007068287A1 (en) * 2005-12-15 2007-06-21 Laboratoria Qualiphar Sustained release vitamin preparation
US11007204B2 (en) 2006-02-03 2021-05-18 Opko Renal, Llc Treating vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
US11911398B2 (en) 2006-02-03 2024-02-27 Opko Renal, Llc Treating Vitamin D insufficiency and deficiency with 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3
US10668089B2 (en) 2006-06-21 2020-06-02 Opko Ireland Global Holdings, Ltd. Method of treating and preventing secondary hyperparathyroidism
US8703187B2 (en) 2007-04-25 2014-04-22 Warner Chilcott Company, Llc Vitamin D content uniformity in pharmaceutical dosage forms
US11752158B2 (en) 2007-04-25 2023-09-12 Eirgen Pharma Ltd. Method of treating vitamin D insufficiency and deficiency
US11154509B2 (en) 2007-04-25 2021-10-26 Eirgen Pharma Ltd. Methods for controlled release oral dosage of a vitamin D compound
US11672809B2 (en) 2010-03-29 2023-06-13 Eirgen Pharma Ltd. Methods and compositions for reducing parathyroid levels
EP2468265A3 (en) * 2010-12-04 2013-01-02 DEEF Pharmaceutical Industries Co. Homogeneous preparations containing vitamin D
EP3332773B1 (en) 2013-03-15 2020-08-26 OPKO Ireland Global Holdings, Limited Stabilized modified release vitamin d formulation and method of administering same
EP3650016B1 (en) 2013-03-15 2021-05-05 EirGen Pharma Ltd. Stabilized modified release vitamin d formulation and method of administering same
EP2968172B1 (en) 2013-03-15 2020-07-22 EirGen Pharma Ltd. Stabilized modified release vitamin d formulation and method of administring same
US11253528B2 (en) 2013-03-15 2022-02-22 Eirgen Pharma Ltd. Stabilized modified release Vitamin D formulation and method of administering same
US10357502B2 (en) 2013-03-15 2019-07-23 Opko Ireland Global Holdings, Ltd. Stabilized modified release vitamin D formulation and method of administering same
US10350224B2 (en) 2013-03-15 2019-07-16 Opko Ireland Global Holdings, Ltd. Stabilized modified release vitamin D formulation and method of administering same
US10300078B2 (en) 2013-03-15 2019-05-28 Opko Ireland Global Holdings, Ltd. Stabilized modified release vitamin D formulation and method of administering same
US11007205B2 (en) 2014-08-07 2021-05-18 Eirgen Pharma Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US10493084B2 (en) 2014-08-07 2019-12-03 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US11738033B2 (en) 2014-08-07 2023-08-29 Eirgen Pharma Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
US11173168B2 (en) 2016-03-28 2021-11-16 Eirgen Pharma Ltd. Methods of treating vitamin D insufficiency in chronic kidney disease

Also Published As

Publication number Publication date
AU8096591A (en) 1992-06-25
EP0559645A1 (en) 1993-09-15
JPH04198129A (ja) 1992-07-17

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